SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2IP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1i9z PHOSPHATIDYLINOSITOL
PHOSPHATE
PHOSPHATASE
(Schizosaccharomy
ces
pombe) 		4 / 8 ARG A 744
HIS A 839
ASP A 816
ALA A 702
 2IP  A 302 (-2.8A)
None
None
2IP  A 302 ( 3.8A)
 0.94A 2rk8A-1i9zA:
3.1		 2rk8A-1i9zA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1i9z PHOSPHATIDYLINOSITOL
PHOSPHATE
PHOSPHATASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 744
ASP A 713
ASN A 706
 2IP  A 302 (-2.8A)
None
None
 0.58A 2zzmA-1i9zA:
1.8		 2zzmA-1i9zA:
21.56