SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2HN'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIK_A_ADNA799_1 (ADENOSINE KINASE)	4b6s	3-DEHYDROQUINATE DEHYDRATASE (Helicobacter pylori)	5 / 10	THR A 104 GLY A 130 VAL A 101 ASN A 76 ILE A 30	2HN A 200 (-2.9A) None None 2HN A 200 (-3.0A) None	1.11A	1likA-4b6sA: undetectable	1likA-4b6sA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ECX_A_SAMA1301_0 (STIE PROTEIN)	4b6s	3-DEHYDROQUINATE DEHYDRATASE (Helicobacter pylori)	5 / 12	LEU A 11 GLY A 133 GLY A 130 VAL A 101 ILE A 74	2HN A 200 (-4.3A) None None None None	0.98A	6ecxA-4b6sA: undetectable	6ecxA-4b6sA: 16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6JOG_A_ASCA201_0 (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE)	4b6s	3-DEHYDROQUINATE DEHYDRATASE (Helicobacter pylori)	4 / 6	GLY A 119 THR A 118 HIS A 102 ARG A 113	None None 2HN A 200 (-4.0A) 2HN A 200 (-3.7A)	1.07A	6jogA-4b6sA: undetectable	6jogA-4b6sA: 22.09