SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2HA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1un9 DIHYDROXYACETONE
KINASE
(Citrobacter
freundii) 		6 / 11 LEU A  32
ALA A  90
GLY A  57
GLY A  56
VAL A  42
ILE A  40
 None
None
2HA  A1554 (-3.3A)
None
None
None
 1.40A 1sduA-1un9A:
undetectable		 1sduA-1un9A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 1un9 DIHYDROXYACETONE
KINASE
(Citrobacter
freundii) 		4 / 6 HIS A  61
PHE A   4
GLN A 200
PRO A 199
 2HA  A1554 (-3.7A)
None
None
None
 1.33A 2qqtA-1un9A:
0.0		 2qqtA-1un9A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 1un9 DIHYDROXYACETONE
KINASE
(Citrobacter
freundii) 		5 / 12 ALA A  90
GLY A  57
GLY A  56
VAL A  42
ILE A  40
 None
2HA  A1554 (-3.3A)
None
None
None
 0.91A 3cyxB-1un9A:
undetectable		 3cyxB-1un9A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 1un9 DIHYDROXYACETONE
KINASE
(Citrobacter
freundii) 		4 / 6 HIS A  61
PHE A   4
GLN A 200
PRO A 199
 2HA  A1554 (-3.7A)
None
None
None
 1.32A 3gclA-1un9A:
0.3		 3gclA-1un9A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_SALA601_1
(SALICYLATE-AMP
LIGASE)		 1un9 DIHYDROXYACETONE
KINASE
(Citrobacter
freundii) 		5 / 9 GLY A  58
VAL A  82
GLY A  60
LEU A 298
LYS A 109
 2HA  A1554 (-3.7A)
None
None
None
2HA  A1554 (-2.4A)
 1.36A 5wm2A-1un9A:
4.1		 5wm2A-1un9A:
9.42