SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2H3'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 4n54 INOSITOL
DEHYDROGENASE
(Lactobacillus
casei) 		4 / 6 TYR A 247
ARG A 290
PHE A 287
PHE A 295
 2H3  A 402 (-4.5A)
None
NAI  A 401 ( 3.7A)
NAI  A 401 (-4.9A)
 0.97A 3af3A-4n54A:
undetectable		 3af3A-4n54A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 4n54 INOSITOL
DEHYDROGENASE
(Lactobacillus
casei) 		4 / 8 PHE A 170
PHE A 167
GLY A  14
MET A 183
 NAI  A 401 (-4.1A)
None
NAI  A 401 (-3.1A)
2H3  A 402 (-3.5A)
 0.97A 3ko0B-4n54A:
undetectable
3ko0J-4n54A:
undetectable		 3ko0B-4n54A:
13.88
3ko0J-4n54A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 4n54 INOSITOL
DEHYDROGENASE
(Lactobacillus
casei) 		4 / 7 GLY A  14
MET A 183
PHE A 170
PHE A 167
 NAI  A 401 (-3.1A)
2H3  A 402 (-3.5A)
NAI  A 401 (-4.1A)
None
 0.88A 3ko0M-4n54A:
undetectable
3ko0P-4n54A:
undetectable		 3ko0M-4n54A:
13.88
3ko0P-4n54A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 4n54 INOSITOL
DEHYDROGENASE
(Lactobacillus
casei) 		4 / 7 PHE A 170
PHE A 167
GLY A  14
MET A 183
 NAI  A 401 (-4.1A)
None
NAI  A 401 (-3.1A)
2H3  A 402 (-3.5A)
 0.92A 3ko0K-4n54A:
undetectable
3ko0S-4n54A:
undetectable		 3ko0K-4n54A:
13.88
3ko0S-4n54A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 4n54 INOSITOL
DEHYDROGENASE
(Lactobacillus
casei) 		4 / 7 PHE A 170
PHE A 167
GLY A  14
MET A 183
 NAI  A 401 (-4.1A)
None
NAI  A 401 (-3.1A)
2H3  A 402 (-3.5A)
 0.99A 3ko0R-4n54A:
undetectable
3ko0T-4n54A:
undetectable		 3ko0R-4n54A:
13.88
3ko0T-4n54A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 4n54 INOSITOL
DEHYDROGENASE
(Lactobacillus
casei) 		4 / 5 ARG A 290
PRO A 266
TYR A 247
VAL A 265
 None
None
2H3  A 402 (-4.5A)
None
 1.39A 3sufC-4n54A:
undetectable		 3sufC-4n54A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 4n54 INOSITOL
DEHYDROGENASE
(Lactobacillus
casei) 		5 / 12 ASP A 159
SER A  97
HIS A 186
GLY A 322
TYR A 247
 2H3  A 402 (-2.8A)
None
2H3  A 402 ( 3.8A)
None
2H3  A 402 (-4.5A)
 1.22A 4kn2C-4n54A:
undetectable		 4kn2C-4n54A:
19.08