SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2FD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 10 ARG A  87
THR A  90
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.52A 1jdvA-1z34A:
33.7
1jdvD-1z34A:
33.7		 1jdvA-1z34A:
34.87
1jdvD-1z34A:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 10 ARG A  87
THR A  90
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.50A 1jdvB-1z34A:
33.9
1jdvC-1z34A:
19.4		 1jdvB-1z34A:
34.87
1jdvC-1z34A:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 10 ARG A  87
THR A  90
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.51A 1jdvA-1z34A:
33.7
1jdvD-1z34A:
33.7		 1jdvA-1z34A:
34.87
1jdvD-1z34A:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 12 ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.49A 1jdvE-1z34A:
21.2
1jdvF-1z34A:
33.7		 1jdvE-1z34A:
34.87
1jdvF-1z34A:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.55A 1odiA-1z34A:
36.0		 1odiA-1z34A:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.55A 1odiB-1z34A:
35.7		 1odiB-1z34A:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-2.8A)
None
 1.48A 1odiC-1z34A:
36.1		 1odiC-1z34A:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.48A 1odiC-1z34A:
36.1		 1odiC-1z34A:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.55A 1odiD-1z34A:
36.0		 1odiD-1z34A:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.48A 1odiE-1z34A:
35.9		 1odiE-1z34A:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.51A 1odiF-1z34A:
35.9		 1odiF-1z34A:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 9 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.37A 1pk7A-1z34A:
38.6		 1pk7A-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 8 ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.66A 1pk7B-1z34A:
39.0		 1pk7B-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 10 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.45A 1pk7C-1z34A:
38.8		 1pk7C-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 10 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.36A 1pk9A-1z34A:
38.5		 1pk9A-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 9 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.33A 1pk9B-1z34A:
38.8		 1pk9B-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.49A 1pk9C-1z34A:
37.6		 1pk9C-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.42A 1pw7A-1z34A:
38.5		 1pw7A-1z34A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 9 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
 0.45A 1pw7B-1z34A:
39.0		 1pw7B-1z34A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 9 MET A  64
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.49A 1pw7C-1z34A:
38.9		 1pw7C-1z34A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
 0.34A 1vhwA-1z34A:
39.7
1vhwD-1z34A:
39.8		 1vhwA-1z34A:
54.36
1vhwD-1z34A:
54.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 9 MET A  64
ARG A  87
GLY A  92
VAL A 178
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.32A 1vhwB-1z34A:
39.4
1vhwF-1z34A:
39.6		 1vhwB-1z34A:
54.36
1vhwF-1z34A:
54.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
 0.36A 1vhwC-1z34A:
39.9
1vhwE-1z34A:
39.6		 1vhwC-1z34A:
54.36
1vhwE-1z34A:
54.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
 0.37A 1vhwA-1z34A:
39.7
1vhwD-1z34A:
39.8		 1vhwA-1z34A:
54.36
1vhwD-1z34A:
54.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
 0.34A 1vhwC-1z34A:
39.9
1vhwE-1z34A:
39.6		 1vhwC-1z34A:
54.36
1vhwE-1z34A:
54.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 10 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.31A 1vhwB-1z34A:
39.4
1vhwF-1z34A:
39.6		 1vhwB-1z34A:
54.36
1vhwF-1z34A:
54.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		10 / 10 MET A  64
ARG A  87
THR A  90
GLY A  92
THR A 156
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.4A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.18A 1z35A-1z34A:
45.1		 1z35A-1z34A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		5 / 9 ARG A  87
THR A  90
MET A  64
GLU A 181
SER A 203
 2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.8A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 1.46A 1z37A-1z34A:
44.5		 1z37A-1z34A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 9 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.36A 1z37A-1z34A:
44.5		 1z37A-1z34A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.46A 2ac7A-1z34A:
36.5
2ac7B-1z34A:
36.5		 2ac7A-1z34A:
47.66
2ac7B-1z34A:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.47A 2ac7A-1z34A:
36.5
2ac7B-1z34A:
36.5		 2ac7A-1z34A:
47.66
2ac7B-1z34A:
47.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.4A)
None
2FD  A 300 (-3.7A)
 0.60A 3kvrA-1z34A:
24.1		 3kvrA-1z34A:
26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.4A)
None
2FD  A 300 (-3.7A)
 0.56A 3kvrB-1z34A:
24.0		 3kvrB-1z34A:
26.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 9 MET A  64
ARG A  87
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.56A 3u40A-1z34A:
35.8
3u40F-1z34A:
36.2		 3u40A-1z34A:
45.61
3u40F-1z34A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 10 MET A  64
ARG A  87
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.56A 3u40B-1z34A:
21.8
3u40C-1z34A:
36.3		 3u40B-1z34A:
45.61
3u40C-1z34A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 12 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.49A 3u40B-1z34A:
21.8
3u40C-1z34A:
36.3		 3u40B-1z34A:
45.61
3u40C-1z34A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.49A 3u40D-1z34A:
35.4
3u40E-1z34A:
35.4		 3u40D-1z34A:
45.61
3u40E-1z34A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 12 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.52A 3u40D-1z34A:
35.4
3u40E-1z34A:
35.4		 3u40D-1z34A:
45.61
3u40E-1z34A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 10 MET A  64
ARG A  87
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.50A 3u40A-1z34A:
35.8
3u40F-1z34A:
36.2		 3u40A-1z34A:
45.61
3u40F-1z34A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		10 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.51A 3uawA-1z34A:
23.8		 3uawA-1z34A:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		9 / 10 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-4.2A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
 0.44A 3uayA-1z34A:
37.4		 3uayA-1z34A:
47.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.41A 4d9hA-1z34A:
36.8		 4d9hA-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		5 / 9 MET A  64
GLY A  92
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 (-3.1A)
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.60A 4da6A-1z34A:
36.3		 4da6A-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		5 / 9 MET A  64
GLY A  92
VAL A 178
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.36A 4da6A-1z34A:
36.3		 4da6A-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 10 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.45A 4da7A-1z34A:
36.6		 4da7A-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.50A 4danA-1z34A:
36.1		 4danA-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.40A 4danA-1z34A:
36.1		 4danA-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 12 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
 0.56A 4danA-1z34A:
36.1
4danB-1z34A:
36.4		 4danA-1z34A:
46.51
4danB-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		6 / 12 ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
 0.43A 4danA-1z34A:
36.1
4danB-1z34A:
36.4		 4danA-1z34A:
46.51
4danB-1z34A:
46.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		7 / 9 MET A  64
ARG A  87
GLY A  92
VAL A 178
MET A 180
GLU A 181
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 ( 4.5A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
 0.47A 5i3cA-1z34A:
39.2		 5i3cA-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 10 MET A  64
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ASP A 204
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
None
None
 0.47A 5i3cB-1z34A:
39.3		 5i3cB-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ASP A 204
 2FD  A 300 (-3.8A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.68A 5i3cC-1z34A:
39.1		 5i3cC-1z34A:
58.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Trichomonas
vaginalis) 		8 / 11 MET A  64
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 2FD  A 300 (-3.8A)
2FD  A 300 (-3.1A)
2FD  A 300 (-4.7A)
None
2FD  A 300 (-3.7A)
2FD  A 300 (-2.8A)
2FD  A 300 (-3.6A)
None
 0.50A 5i3cC-1z34A:
39.1		 5i3cC-1z34A:
58.72