SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2F1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_A_MOAA1332_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	5 / 11	ASN A 273 GLY A 296 CYH A 301 THR A 303 GLY A 385	IMP A 500 ( 4.1A) None IMP A 500 ( 3.1A) 2F1 A 501 (-4.1A) IMP A 500 ( 3.3A)	0.35A	1jr1A-4mz1A: 53.8	1jr1A-4mz1A: 37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_A_MOAA1332_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	5 / 11	ASP A 244 ASN A 273 GLY A 296 THR A 303 GLY A 385	None IMP A 500 ( 4.1A) None 2F1 A 501 (-4.1A) IMP A 500 ( 3.3A)	0.78A	1jr1A-4mz1A: 53.8	1jr1A-4mz1A: 37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_A_MOAA1332_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	5 / 11	ASP A 244 SER A 245 GLY A 296 THR A 303 GLY A 385	None None None 2F1 A 501 (-4.1A) IMP A 500 ( 3.3A)	1.15A	1jr1A-4mz1A: 53.8	1jr1A-4mz1A: 37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_A_MOAA1332_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	5 / 11	SER A 245 GLY A 296 CYH A 301 THR A 303 GLY A 385	None None IMP A 500 ( 3.1A) 2F1 A 501 (-4.1A) IMP A 500 ( 3.3A)	0.70A	1jr1A-4mz1A: 53.8	1jr1A-4mz1A: 37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_B_MOAB1333_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	4 / 8	ASN A 273 GLY A 296 THR A 303 GLY A 385	IMP A 500 ( 4.1A) None 2F1 A 501 (-4.1A) IMP A 500 ( 3.3A)	0.30A	1jr1B-4mz1A: 53.6	1jr1B-4mz1A: 37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JR1_B_MOAB1333_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	4 / 8	ASP A 244 ASN A 273 GLY A 296 THR A 303	None IMP A 500 ( 4.1A) None 2F1 A 501 (-4.1A)	0.82A	1jr1B-4mz1A: 53.6	1jr1B-4mz1A: 37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FO4_A_MOAA502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	7 / 8	ASP A 244 SER A 245 ASN A 273 CYH A 301 THR A 303 MET A 384 GLY A 385	None None IMP A 500 ( 4.1A) IMP A 500 ( 3.1A) 2F1 A 501 (-4.1A) None IMP A 500 ( 3.3A)	0.37A	4fo4A-4mz1A: 55.9	4fo4A-4mz1A: 59.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FO4_B_MOAB502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	7 / 8	SER A 245 ASN A 273 GLY A 296 CYH A 301 THR A 303 MET A 384 GLY A 385	None IMP A 500 ( 4.1A) None IMP A 500 ( 3.1A) 2F1 A 501 (-4.1A) None IMP A 500 ( 3.3A)	0.31A	4fo4B-4mz1A: 51.3	4fo4B-4mz1A: 59.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FXS_A_MOAA702_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	4mz1	INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE (Campylobacter jejuni)	7 / 9	SER A 245 ASN A 273 ILE A 295 GLY A 296 CYH A 301 THR A 303 ASP A 334	None IMP A 500 ( 4.1A) None None IMP A 500 ( 3.1A) 2F1 A 501 (-4.1A) IMP A 500 (-2.6A)	0.31A	4fxsA-4mz1A: 57.6	4fxsA-4mz1A: 48.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JR1_A_MOAA1332_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",5,"ASN A 273;GLY A 296;CYH A 301;THR A 303;GLY A 385","IMP A 500 ( 4.1A);None;IMP A 500 ( 3.1A);2F1 A 501 (-4.1A);IMP A 500 ( 3.3A)","0.35A","1jr1A-4mz1A:53.8",null],["1JR1_A_MOAA1332_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",5,"ASP A 244;ASN A 273;GLY A 296;THR A 303;GLY A 385","None;IMP A 500 ( 4.1A);None;2F1 A 501 (-4.1A);IMP A 500 ( 3.3A)","0.78A","1jr1A-4mz1A:53.8","1jr1A-4mz1A:37.02"],["1JR1_A_MOAA1332_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",5,"ASP A 244;SER A 245;GLY A 296;THR A 303;GLY A 385","None;None;None;2F1 A 501 (-4.1A);IMP A 500 ( 3.3A)","1.15A","1jr1A-4mz1A:53.8","1jr1A-4mz1A:37.02"],["1JR1_A_MOAA1332_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",5,"SER A 245;GLY A 296;CYH A 301;THR A 303;GLY A 385","None;None;IMP A 500 ( 3.1A);2F1 A 501 (-4.1A);IMP A 500 ( 3.3A)","0.70A","1jr1A-4mz1A:53.8","1jr1A-4mz1A:37.02"],["1JR1_B_MOAB1333_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",4,"ASN A 273;GLY A 296;THR A 303;GLY A 385","IMP A 500 ( 4.1A);None;2F1 A 501 (-4.1A);IMP A 500 ( 3.3A)","0.30A","1jr1B-4mz1A:53.6","1jr1A-4mz1A:37.02"],["1JR1_B_MOAB1333_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",4,"ASP A 244;ASN A 273;GLY A 296;THR A 303","None;IMP A 500 ( 4.1A);None;2F1 A 501 (-4.1A)","0.82A","1jr1B-4mz1A:53.6","1jr1B-4mz1A:37.02"],["4FO4_A_MOAA502_1","INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",7,"ASP A 244;SER A 245;ASN A 273;CYH A 301;THR A 303;MET A 384;GLY A 385","None;None;IMP A 500 ( 4.1A);IMP A 500 ( 3.1A);2F1 A 501 (-4.1A);None;IMP A 500 ( 3.3A)","0.37A","4fo4A-4mz1A:55.9","1jr1B-4mz1A:37.02"],["4FO4_B_MOAB502_1","INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",7,"SER A 245;ASN A 273;GLY A 296;CYH A 301;THR A 303;MET A 384;GLY A 385","None;IMP A 500 ( 4.1A);None;IMP A 500 ( 3.1A);2F1 A 501 (-4.1A);None;IMP A 500 ( 3.3A)","0.31A","4fo4B-4mz1A:51.3","4fo4A-4mz1A:59.02"],["4FXS_A_MOAA702_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","4mz1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","Campylobacter jejuni",7,"SER A 245;ASN A 273;ILE A 295;GLY A 296;CYH A 301;THR A 303;ASP A 334","None;IMP A 500 ( 4.1A);None;None;IMP A 500 ( 3.1A);2F1 A 501 (-4.1A);IMP A 500 (-2.6A)","0.31A","4fxsA-4mz1A:57.6","4fo4B-4mz1A:59.02"]]