SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2BA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5f29 NA+/H+
ANTIPORTER-LIKE
PROTEIN
(Staphylococcus
aureus) 		4 / 7 PRO A 183
THR A 187
GLY A 185
LEU A 195
 2BA  A 301 (-4.6A)
None
2BA  A 301 (-2.9A)
None
 1.03A 2vl2B-5f29A:
undetectable		 2vl2B-5f29A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4s1b LMO1466 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLN A 558
ASP A 648
VAL A 518
ASP A 544
HIS A 605
 2BA  A 803 ( 4.2A)
FE  A 802 ( 2.6A)
None
FE  A 802 (-2.7A)
FE  A 801 ( 3.5A)
 1.24A 2x2iB-4s1bA:
undetectable		 2x2iB-4s1bA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4s1b LMO1466 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLN A 558
ASP A 648
VAL A 518
ASP A 544
HIS A 605
 2BA  A 803 ( 4.2A)
FE  A 802 ( 2.6A)
None
FE  A 802 (-2.7A)
FE  A 801 ( 3.5A)
 1.26A 2x2iD-4s1bA:
undetectable		 2x2iD-4s1bA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_C_SPMC503_1
(SPERMIDINE SYNTHASE)		 4s1b LMO1466 PROTEIN
(Listeria
monocytogenes) 		5 / 12 HIS A 604
ASP A 648
ASP A 544
SER A 573
ILE A 577
 FE  A 801 (-3.5A)
FE  A 802 ( 2.6A)
FE  A 802 (-2.7A)
None
2BA  A 803 (-3.9A)
 1.32A 3b7pC-4s1bA:
undetectable		 3b7pC-4s1bA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4s1b LMO1466 PROTEIN
(Listeria
monocytogenes) 		4 / 5 THR A 581
GLY A 546
GLU A 556
HIS A 514
 None
None
2BA  A 803 (-2.9A)
FE  A 802 ( 3.4A)
 1.17A 5c0oH-4s1bA:
undetectable		 5c0oH-4s1bA:
21.45