SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2AN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 PHE A  16
PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 4.3A)
2AN  A 201 ( 4.0A)
None
2AN  A 201 ( 4.9A)
None
 0.70A 1cbrA-3wbgA:
19.3		 1cbrA-3wbgA:
39.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 PHE A  16
PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 4.3A)
2AN  A 201 ( 4.0A)
None
2AN  A 201 ( 4.9A)
None
 0.70A 1cbrB-3wbgA:
19.3		 1cbrB-3wbgA:
39.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 PHE A  16
PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 4.3A)
2AN  A 201 ( 4.0A)
None
2AN  A 201 ( 4.9A)
None
 0.75A 1cbsA-3wbgA:
19.0		 1cbsA-3wbgA:
41.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 TYR A  19
LEU A 104
THR A  53
ASP A  76
 2AN  A 201 (-4.8A)
None
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
 1.02A 1dz9A-3wbgA:
undetectable		 1dz9A-3wbgA:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
ALA A  33
PRO A  38
SER A  55
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.2A)
None
 0.70A 1kglA-3wbgA:
19.8		 1kglA-3wbgA:
32.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
TYR A  19
ALA A  33
PRO A  38
THR A  40
 2AN  A 201 ( 4.9A)
2AN  A 201 (-4.8A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.3A)
None
 1.07A 1mx8A-3wbgA:
17.1		 1mx8A-3wbgA:
34.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
TYR A  19
ALA A  33
PRO A  38
THR A  53
 2AN  A 201 ( 4.9A)
2AN  A 201 (-4.8A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.3A)
2AN  A 201 ( 4.0A)
 1.11A 1mx8A-3wbgA:
17.1		 1mx8A-3wbgA:
34.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 TYR A  19
LEU A 104
THR A  53
ASP A  76
 2AN  A 201 (-4.8A)
None
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
 1.06A 1o76B-3wbgA:
undetectable		 1o76B-3wbgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 TYR A  19
LEU A 104
THR A  60
ASP A  76
 2AN  A 201 (-4.8A)
None
None
2AN  A 201 (-3.9A)
 0.89A 1o76B-3wbgA:
undetectable		 1o76B-3wbgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 TYR A  19
LEU A 104
THR A  53
ASP A  76
 2AN  A 201 (-4.8A)
None
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
 1.03A 1uyuA-3wbgA:
undetectable		 1uyuA-3wbgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 TYR A  19
LEU A 104
THR A  53
ASP A  76
 2AN  A 201 (-4.8A)
None
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
 1.03A 1uyuB-3wbgA:
undetectable		 1uyuB-3wbgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		4 / 5 GLY A 139
PRO A  36
ALA A  57
ILE A  55
 2AN  A 716 (-3.7A)
2AN  A 715 (-4.4A)
2AN  A 716 (-3.4A)
2AN  A 716 (-4.2A)
 0.96A 2aofA-1txcA:
undetectable		 2aofA-1txcA:
23.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 PHE A  16
VAL A  32
THR A  53
LEU A 115
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
None
2AN  A 201 ( 4.0A)
None
2AN  A 201 ( 4.9A)
None
 0.87A 2cbrA-3wbgA:
19.3		 2cbrA-3wbgA:
39.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 PHE A  16
PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 4.3A)
2AN  A 201 ( 4.0A)
None
2AN  A 201 ( 4.9A)
None
 0.77A 2fr3A-3wbgA:
19.2		 2fr3A-3wbgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
ALA A  33
THR A  40
ARG A 106
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 (-3.8A)
None
None
None
 1.07A 2g78A-3wbgA:
19.2		 2g78A-3wbgA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		10 / 12 PHE A  16
VAL A  25
ALA A  33
SER A  55
THR A  60
ALA A  75
ASP A  76
ARG A  78
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
None
2AN  A 201 (-3.8A)
2AN  A 201 (-3.2A)
None
2AN  A 201 ( 3.8A)
2AN  A 201 (-3.9A)
2AN  A 201 ( 4.8A)
2AN  A 201 ( 4.9A)
None
 0.66A 2qm9A-3wbgA:
25.0		 2qm9A-3wbgA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		7 / 12 VAL A  25
ALA A  33
SER A  55
ALA A  75
ASP A  76
CYH A 124
TYR A 128
 None
2AN  A 201 (-3.8A)
2AN  A 201 (-3.2A)
2AN  A 201 ( 3.8A)
2AN  A 201 (-3.9A)
None
None
 1.28A 2qm9A-3wbgA:
25.0		 2qm9A-3wbgA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 VAL A  25
ALA A  33
THR A  53
ASP A  76
ARG A  78
 None
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
2AN  A 201 ( 4.8A)
 1.09A 2qm9A-3wbgA:
25.0		 2qm9A-3wbgA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 VAL A  25
ALA A  33
THR A  53
ASP A  76
CYH A 124
 None
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
None
 1.04A 2qm9A-3wbgA:
25.0		 2qm9A-3wbgA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		9 / 12 PHE A  16
TYR A  19
VAL A  25
SER A  55
THR A  60
ALA A  75
ARG A  78
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 (-4.8A)
None
2AN  A 201 (-3.2A)
None
2AN  A 201 ( 3.8A)
2AN  A 201 ( 4.8A)
2AN  A 201 ( 4.9A)
None
 0.62A 2qm9B-3wbgA:
25.5		 2qm9B-3wbgA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 VAL A  25
SER A  55
ALA A  75
CYH A 124
TYR A 128
 None
2AN  A 201 (-3.2A)
2AN  A 201 ( 3.8A)
None
None
 1.21A 2qm9B-3wbgA:
25.5		 2qm9B-3wbgA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 4 MET A  20
PRO A  38
ASP A  76
ARG A 106
 2AN  A 201 ( 3.9A)
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.9A)
None
 0.51A 2qm9B-3wbgA:
25.5		 2qm9B-3wbgA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
MET A  20
ALA A  33
THR A  53
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
None
 0.73A 2rctA-3wbgA:
20.2		 2rctA-3wbgA:
38.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 TYR A  19
LEU A 104
THR A  53
ASP A  76
 2AN  A 201 (-4.8A)
None
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
 1.02A 2zaxA-3wbgA:
undetectable		 2zaxA-3wbgA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 TYR A  19
LEU A 104
THR A  53
ASP A  76
 2AN  A 201 (-4.8A)
None
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
 1.05A 3fwgB-3wbgA:
undetectable		 3fwgB-3wbgA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 2wor PROTEIN S100-A7
(Homo
sapiens) 		4 / 8 GLY A  79
ILE A   9
MET A  12
PHE A  16
 None
None
2AN  A1098 ( 3.8A)
None
 0.70A 3ko0O-2worA:
11.3
3ko0Q-2worA:
11.8		 3ko0O-2worA:
25.71
3ko0Q-2worA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		5 / 12 PHE A 119
TYR A  82
TYR A  80
PHE A 142
ILE A  55
 None
None
None
2AN  A 716 ( 4.2A)
2AN  A 716 (-4.2A)
 1.43A 3ld6B-1txcA:
undetectable		 3ld6B-1txcA:
15.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		9 / 12 PHE A  16
MET A  20
VAL A  25
PRO A  38
ASP A  76
ARG A  78
ARG A 106
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
None
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.9A)
2AN  A 201 ( 4.8A)
None
2AN  A 201 ( 4.9A)
None
 0.72A 3p6gA-3wbgA:
24.8		 3p6gA-3wbgA:
59.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		8 / 12 PHE A  16
MET A  20
VAL A  25
PRO A  38
ASP A  76
CYH A 124
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
None
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.9A)
None
2AN  A 201 ( 4.9A)
None
 1.16A 3p6gA-3wbgA:
24.8		 3p6gA-3wbgA:
59.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 7 PHE A  16
MET A  20
ASP A  76
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.9A)
2AN  A 201 ( 4.9A)
None
 0.51A 3p6hA-3wbgA:
24.8		 3p6hA-3wbgA:
59.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		5 / 12 ASP A  27
LYS A  53
ILE A  55
VAL A  66
TYR A  80
 None
None
2AN  A 716 (-4.2A)
2AN  A 716 (-4.0A)
None
 0.80A 4a81A-1txcA:
21.9		 4a81A-1txcA:
40.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 GLN A  95
PHE A  70
THR A  53
THR A  60
 None
None
2AN  A 201 ( 4.0A)
None
 0.84A 4n16A-3wbgA:
undetectable		 4n16A-3wbgA:
18.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
MET A  20
ALA A  33
THR A  53
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
None
 0.80A 4qynA-3wbgA:
20.6		 4qynA-3wbgA:
37.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
MET A  20
THR A  53
LEU A 115
LEU A 117
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 ( 4.0A)
None
None
 0.81A 4qynB-3wbgA:
20.6		 4qynB-3wbgA:
37.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 6 TYR A  19
GLU A  72
THR A  74
GLN A  95
 2AN  A 201 (-4.8A)
None
None
None
 0.75A 4qztA-3wbgA:
20.9		 4qztA-3wbgA:
37.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
MET A  20
ALA A  33
THR A  53
LEU A 104
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
None
 1.33A 4qzuB-3wbgA:
21.1		 4qzuB-3wbgA:
37.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
MET A  20
ALA A  33
THR A  53
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
None
 0.72A 4qzuB-3wbgA:
21.1		 4qzuB-3wbgA:
37.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 6 TYR A  19
GLU A  72
THR A  74
GLN A  95
LEU A 117
 2AN  A 201 (-4.8A)
None
None
None
None
 0.69A 4qzuC-3wbgA:
21.0		 4qzuC-3wbgA:
37.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 PHE A  16
MET A  20
ALA A  33
THR A  53
LEU A 115
LEU A 117
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
None
None
 0.63A 4qzuC-3wbgA:
21.0		 4qzuC-3wbgA:
37.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_B_QDNB602_1
(CYTOCHROME P450 2D6)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		5 / 9 LEU A  90
PHE A 119
ALA A 135
ASP A 134
ALA A 130
 None
None
2AN  A 716 ( 4.3A)
None
None
 1.14A 4wnuB-1txcA:
undetectable		 4wnuB-1txcA:
16.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
TYR A  19
ALA A  33
SER A  55
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 (-4.8A)
2AN  A 201 (-3.8A)
2AN  A 201 (-3.2A)
None
 0.63A 5h8tA-3wbgA:
20.5		 5h8tA-3wbgA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		7 / 12 PHE A  16
TYR A  19
VAL A  25
ALA A  33
PRO A  38
SER A  55
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 (-4.8A)
None
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.2A)
None
 0.81A 5hbsA-3wbgA:
20.3		 5hbsA-3wbgA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 PHE A  16
TYR A  19
ALA A  33
PRO A  38
SER A  55
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 (-4.8A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.2A)
None
 0.93A 5ljbA-3wbgA:
20.3		 5ljbA-3wbgA:
32.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
TYR A  19
ALA A  33
SER A  55
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 (-4.8A)
2AN  A 201 (-3.8A)
2AN  A 201 (-3.2A)
None
 0.75A 5ljcA-3wbgA:
20.5		 5ljcA-3wbgA:
33.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 TYR A  19
ALA A  33
PRO A  38
SER A  55
LEU A 115
 2AN  A 201 (-4.8A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.2A)
None
 0.83A 5ljcA-3wbgA:
20.5		 5ljcA-3wbgA:
33.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PHE A  16
ALA A  33
PRO A  38
SER A  55
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.3A)
2AN  A 201 (-3.2A)
None
 0.77A 5ljeA-3wbgA:
20.7		 5ljeA-3wbgA:
33.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 GLN A  95
PHE A  70
THR A  53
THR A  60
 None
None
2AN  A 201 ( 4.0A)
None
 0.95A 5m78A-3wbgA:
undetectable		 5m78A-3wbgA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3wbg FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 TYR A  19
LEU A 104
THR A  53
ASP A  76
 2AN  A 201 (-4.8A)
None
2AN  A 201 ( 4.0A)
2AN  A 201 (-3.9A)
 1.00A 6cp4A-3wbgA:
undetectable		 6cp4A-3wbgA:
16.63