SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '26G'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4mes THIAMINE TRANSPORTER
THIT
(Lactococcus
lactis) 		4 / 8 GLU A  38
LEU A  92
ALA A  40
ALA A  21
 26G  A 203 (-3.8A)
None
None
None
 0.98A 3ns1L-4mesA:
undetectable		 3ns1L-4mesA:
13.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RLB_A_VIBA191_1
(THIT)		 4mes THIAMINE TRANSPORTER
THIT
(Lactococcus
lactis) 		9 / 10 GLU A  38
GLU A  84
TYR A  85
HIS A 125
GLY A 129
TRP A 133
TYR A 146
VAL A 150
ASN A 151
 26G  A 203 (-3.8A)
26G  A 203 (-2.9A)
26G  A 203 (-4.6A)
26G  A 203 (-3.4A)
26G  A 203 (-3.3A)
26G  A 203 (-3.3A)
26G  A 203 (-4.2A)
26G  A 203 ( 4.5A)
26G  A 203 (-3.3A)
 0.16A 3rlbA-4mesA:
34.1		 3rlbA-4mesA:
94.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RLB_A_VIBA191_1
(THIT)		 4mes THIAMINE TRANSPORTER
THIT
(Lactococcus
lactis) 		6 / 10 TRP A  34
GLY A 129
TRP A 133
TYR A 146
VAL A 150
ASN A 151
 PG4  A 210 (-3.9A)
26G  A 203 (-3.3A)
26G  A 203 (-3.3A)
26G  A 203 (-4.2A)
26G  A 203 ( 4.5A)
26G  A 203 (-3.3A)
 1.01A 3rlbA-4mesA:
34.1		 3rlbA-4mesA:
94.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RLB_B_VIBB187_1
(THIT)		 4mes THIAMINE TRANSPORTER
THIT
(Lactococcus
lactis) 		5 / 12 ILE A  36
GLU A  38
GLU A  84
HIS A 125
TYR A 136
 PG4  A 210 (-4.3A)
26G  A 203 (-3.8A)
26G  A 203 (-2.9A)
26G  A 203 (-3.4A)
None
 1.36A 3rlbB-4mesA:
34.4		 3rlbB-4mesA:
94.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RLB_B_VIBB187_1
(THIT)		 4mes THIAMINE TRANSPORTER
THIT
(Lactococcus
lactis) 		11 / 12 ILE A  36
GLU A  38
GLU A  84
TYR A  85
TYR A 122
HIS A 125
GLY A 129
TRP A 133
TYR A 146
VAL A 150
ASN A 151
 PG4  A 210 (-4.3A)
26G  A 203 (-3.8A)
26G  A 203 (-2.9A)
26G  A 203 (-4.6A)
None
26G  A 203 (-3.4A)
26G  A 203 (-3.3A)
26G  A 203 (-3.3A)
26G  A 203 (-4.2A)
26G  A 203 ( 4.5A)
26G  A 203 (-3.3A)
 0.15A 3rlbB-4mesA:
34.4		 3rlbB-4mesA:
94.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RLB_B_VIBB187_1
(THIT)		 4mes THIAMINE TRANSPORTER
THIT
(Lactococcus
lactis) 		6 / 12 TRP A  34
GLY A 129
TRP A 133
TYR A 146
VAL A 150
ASN A 151
 PG4  A 210 (-3.9A)
26G  A 203 (-3.3A)
26G  A 203 (-3.3A)
26G  A 203 (-4.2A)
26G  A 203 ( 4.5A)
26G  A 203 (-3.3A)
 0.99A 3rlbB-4mesA:
34.4		 3rlbB-4mesA:
94.79