SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '261'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1oh9 ACETYLGLUTAMATE
KINASE
(Escherichia
coli) 		4 / 5 LEU A  14
SER A 147
LEU A  80
GLY A  10
 None
NLG  A1260 ( 3.7A)
NLG  A1260 ( 4.7A)
ALF  A1261 ( 3.1A)
 0.81A 1a4lC-1oh9A:
undetectable		 1a4lC-1oh9A:
22.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 7 HIS A  94
HIS A  96
HIS A 119
THR A 198
THR A 199
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
ZN  A 261 ( 4.4A)
None
None
 0.33A 1am6A-3uyqA:
40.8		 1am6A-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		4 / 7 HIS A 119
HIS A  94
HIS A  96
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
 1.02A 1am6A-3uyqA:
40.8		 1am6A-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 8 HIS A  94
HIS A  96
HIS A 119
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
ZN  A 261 ( 4.4A)
None
 0.27A 1azmA-3uyqA:
41.0		 1azmA-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		4 / 8 HIS A 119
HIS A  94
HIS A  96
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
 1.05A 1azmA-3uyqA:
41.0		 1azmA-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		4 / 8 PHE A 130
HIS A  96
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.4A)
None
 0.87A 1azmA-3uyqA:
41.0		 1azmA-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 8 HIS A  94
HIS A  96
HIS A 119
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
ZN  A 261 ( 4.4A)
None
 0.30A 1bzmA-3uyqA:
41.0		 1bzmA-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.20A 1cilA-3uyqA:
41.0		 1cilA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 12 HIS A  64
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 1cilA-3uyqA:
41.0		 1cilA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 1dmyA-3uyqA:
36.5		 1dmyA-3uyqA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A 119
HIS A  94
HIS A  96
TYR A 193
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.15A 1dmyA-3uyqA:
36.5		 1dmyA-3uyqA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.33A 1dmyB-3uyqA:
36.6		 1dmyB-3uyqA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.31A 1dmyB-3uyqA:
36.6		 1dmyB-3uyqA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A 119
HIS A  94
HIS A  96
TYR A 193
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.13A 1dmyB-3uyqA:
36.6		 1dmyB-3uyqA:
42.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		5 / 12 SER A 151
VAL A 152
GLY A 153
GLY A 195
SER A 218
 NAP  A1261 ( 3.4A)
None
None
None
None
 1.09A 1fduA-2zatA:
26.6		 1fduA-2zatA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		5 / 12 SER A 151
VAL A 152
GLY A 153
TYR A 164
GLY A 195
 NAP  A1261 ( 3.4A)
None
None
NAP  A1261 ( 4.6A)
None
 0.65A 1fduA-2zatA:
26.6		 1fduA-2zatA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		5 / 12 SER A 151
VAL A 152
GLY A 153
GLY A 195
SER A 218
 NAP  A1261 ( 3.4A)
None
None
None
None
 0.87A 1fduC-2zatA:
26.6		 1fduC-2zatA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		5 / 12 SER A 151
VAL A 152
GLY A 153
TYR A 164
GLY A 195
 NAP  A1261 ( 3.4A)
None
None
NAP  A1261 ( 4.6A)
None
 0.63A 1fduC-2zatA:
26.6		 1fduC-2zatA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		5 / 12 ILE B1882
PHE B1883
GLY B1948
MET B2010
LEU B1758
 None
None
None
CU  B2610 ( 3.9A)
None
 1.28A 1fm6X-5k8dB:
undetectable		 1fm6X-5k8dB:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 10 PRO A  57
LEU A 375
PHE A 376
THR A 311
GLY A 261
 PRO  A  57 ( 1.1A)
LEU  A 375 ( 0.6A)
PHE  A 376 ( 1.3A)
THR  A 311 ( 0.8A)
GLY  A 261 ( 0.0A)
 0.92A 1h4oA-4kqnA:
undetectable
1h4oB-4kqnA:
undetectable		 1h4oA-4kqnA:
17.39
1h4oB-4kqnA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 GLU A 147
HIS A 150
ASP A 175
 SAH  A4261 (-2.7A)
SAH  A4261 (-3.6A)
None
 0.85A 1i9gA-1x1bA:
12.9		 1i9gA-1x1bA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		5 / 11 SER A 151
VAL A 152
GLY A 153
TYR A 164
GLY A 195
 NAP  A1261 ( 3.4A)
None
None
NAP  A1261 ( 4.6A)
None
 0.53A 1iolA-2zatA:
27.4		 1iolA-2zatA:
28.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.47A 1jd0A-3uyqA:
36.8		 1jd0A-3uyqA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.28A 1jd0A-3uyqA:
36.8		 1jd0A-3uyqA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.47A 1jd0B-3uyqA:
36.4		 1jd0B-3uyqA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.50A 1jd0B-3uyqA:
36.4		 1jd0B-3uyqA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.33A 1jd0B-3uyqA:
36.4		 1jd0B-3uyqA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.72A 1jd0B-3uyqA:
36.4		 1jd0B-3uyqA:
35.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 4hne PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens) 		4 / 7 GLN A 261
GLU A 193
PHE A 364
ALA A 343
 GLN  A 261 (-0.6A)
GLU  A 193 ( 0.5A)
PHE  A 364 ( 1.3A)
ALA  A 343 ( 0.0A)
 1.36A 1linA-4hneA:
undetectable		 1linA-4hneA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 LEU A 240
LEU A 228
LEU A  60
HIS A  94
TRP A   5
 None
None
None
ZN  A 261 (-3.3A)
None
 1.41A 1mmkA-3uyqA:
undetectable		 1mmkA-3uyqA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4bpt PHENYLALANINE-4-HYDR
OXYLASE (PAH)
(PHE-4-MONOOXYGENASE
)
(Legionella
pneumophila) 		5 / 12 PHE A  91
GLU A 123
HIS A 127
TRP A 163
GLU A 167
 PEG  A1260 (-3.8A)
None
None
PEG  A1262 ( 4.4A)
PEG  A1261 (-3.1A)
 0.89A 1mmkA-4bptA:
26.5		 1mmkA-4bptA:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4bpt PHENYLALANINE-4-HYDR
OXYLASE (PAH)
(PHE-4-MONOOXYGENASE
)
(Legionella
pneumophila) 		5 / 12 VAL A  82
PHE A  91
GLU A 123
HIS A 127
GLU A 167
 None
PEG  A1260 (-3.8A)
None
None
PEG  A1261 (-3.1A)
 0.94A 1mmkA-4bptA:
26.5		 1mmkA-4bptA:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4bpt PHENYLALANINE-4-HYDR
OXYLASE (PAH)
(PHE-4-MONOOXYGENASE
)
(Legionella
pneumophila) 		5 / 11 VAL A  82
PHE A  91
GLU A 123
HIS A 127
GLU A 167
 None
PEG  A1260 (-3.8A)
None
None
PEG  A1261 (-3.1A)
 0.94A 1mmtA-4bptA:
26.6		 1mmtA-4bptA:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  43
THR A  44
SER A  64
MET A  67
HIS A 105
 EDO  A 261 ( 3.9A)
None
None
EDO  A 261 ( 4.1A)
EDO  A 261 ( 4.6A)
 0.83A 1nbiC-3egeA:
14.2		 1nbiC-3egeA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  43
THR A  44
SER A  64
MET A  67
HIS A 105
 EDO  A 261 ( 3.9A)
None
None
EDO  A 261 ( 4.1A)
EDO  A 261 ( 4.6A)
 0.82A 1nbiD-3egeA:
13.6		 1nbiD-3egeA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.86A 1oe1A-5k8dB:
20.7		 1oe1A-5k8dB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 5 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.85A 1oe2A-5k8dB:
20.7		 1oe2A-5k8dB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.84A 1oe3A-5k8dB:
20.8		 1oe3A-5k8dB:
17.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 198
PRO A 201
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
 0.47A 1oq5A-3uyqA:
41.0		 1oq5A-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
 0.38A 1oq5A-3uyqA:
41.0		 1oq5A-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.29A 1oq5A-3uyqA:
41.0		 1oq5A-3uyqA:
58.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 11 GLY A  43
GLY A  45
TYR A  47
ILE A 100
LEU A 179
 EDO  A 261 ( 3.9A)
None
None
None
None
 1.20A 1p91A-3egeA:
12.8		 1p91A-3egeA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 TYR A 246
GLY A 177
TYR A 310
LEU A 245
TYR A 233
 None
SAH  A4261 (-3.8A)
None
None
None
 1.22A 1pj7A-1x1bA:
3.0		 1pj7A-1x1bA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 177
GLY A 178
GLY A 179
LEU A 201
ASP A 227
 SAH  A4261 (-3.8A)
SAH  A4261 ( 4.2A)
SAH  A4261 (-3.3A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
 0.43A 1qzzA-1x1bA:
13.1		 1qzzA-1x1bA:
26.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.45A 1rj6A-3uyqA:
36.7		 1rj6A-3uyqA:
36.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.24A 1rj6A-3uyqA:
36.7		 1rj6A-3uyqA:
36.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.43A 1rj6A-3uyqA:
36.7		 1rj6A-3uyqA:
36.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.45A 1rj6B-3uyqA:
36.4		 1rj6B-3uyqA:
36.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.24A 1rj6B-3uyqA:
36.4		 1rj6B-3uyqA:
36.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 ILE A  40
GLY A  41
GLY A  43
ILE A 100
SER A  64
 None
EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
None
 0.87A 1sg9B-3egeA:
4.1		 1sg9B-3egeA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 12 ASP A  79
HIS A  59
HIS A  54
ASP A  58
HIS A  56
 None
ZN  A 262 ( 3.3A)
ZN  A 261 ( 3.4A)
ZN  A 262 (-2.7A)
ZN  A 261 ( 3.3A)
 1.41A 1t69A-1qh5A:
undetectable		 1t69A-1qh5A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		5 / 12 ASP A 146
HIS A  91
ASP A  43
ASP A 205
TYR A 174
 None
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.4A)
EDO  A 261 (-4.3A)
None
 1.29A 1t69A-3hftA:
undetectable		 1t69A-3hftA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  43
SER A  64
ALA A  84
ILE A 100
HIS A 105
 EDO  A 261 ( 3.9A)
None
None
None
EDO  A 261 ( 4.6A)
 0.80A 1ve3A-3egeA:
16.1		 1ve3A-3egeA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  43
SER A  64
ALA A  84
ILE A 100
HIS A 105
 EDO  A 261 ( 3.9A)
None
None
None
EDO  A 261 ( 4.6A)
 0.85A 1ve3B-3egeA:
16.1		 1ve3B-3egeA:
27.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		6 / 12 ALA A 157
GLY A 177
ILE A 183
ASP A 227
ILE A 228
TYR A 229
 None
SAH  A4261 (-3.8A)
SAH  A4261 ( 4.8A)
SAH  A4261 (-2.9A)
SAH  A4261 (-3.9A)
SAH  A4261 (-4.8A)
 1.37A 1x1aA-1x1bA:
48.6		 1x1aA-1x1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		7 / 12 TYR A 135
ALA A 154
GLY A 178
ILE A 183
LEU A 201
ASP A 227
TYR A 229
 None
SAH  A4261 ( 4.0A)
SAH  A4261 ( 4.2A)
SAH  A4261 ( 4.8A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
SAH  A4261 (-4.8A)
 1.25A 1x1aA-1x1bA:
48.6		 1x1aA-1x1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		12 / 12 TYR A 135
GLU A 147
HIS A 150
ALA A 154
GLY A 177
GLY A 179
ILE A 183
LEU A 201
ASP A 227
ILE A 228
TYR A 229
CYH A 242
 None
SAH  A4261 (-2.7A)
SAH  A4261 (-3.6A)
SAH  A4261 ( 4.0A)
SAH  A4261 (-3.8A)
SAH  A4261 (-3.3A)
SAH  A4261 ( 4.8A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
SAH  A4261 (-3.9A)
SAH  A4261 (-4.8A)
SAH  A4261 (-3.0A)
 0.28A 1x1aA-1x1bA:
48.6		 1x1aA-1x1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		6 / 12 TYR A 135
GLU A 147
HIS A 150
GLY A 178
LEU A 201
CYH A 242
 None
SAH  A4261 (-2.7A)
SAH  A4261 (-3.6A)
SAH  A4261 ( 4.2A)
SAH  A4261 (-4.0A)
SAH  A4261 (-3.0A)
 1.11A 1x1aA-1x1bA:
48.6		 1x1aA-1x1bA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 177
GLY A 178
GLY A 179
LEU A 201
ASP A 227
 SAH  A4261 (-3.8A)
SAH  A4261 ( 4.2A)
SAH  A4261 (-3.3A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
 0.46A 1xdsA-1x1bA:
5.4		 1xdsA-1x1bA:
26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 177
GLY A 178
GLY A 179
LEU A 201
ASP A 227
 SAH  A4261 (-3.8A)
SAH  A4261 ( 4.2A)
SAH  A4261 (-3.3A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
 0.50A 1xdsB-1x1bA:
14.6		 1xdsB-1x1bA:
26.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.41A 1ydaA-3uyqA:
40.4		 1ydaA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
VAL A 142
PHE A 197
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.53A 1ydbA-3uyqA:
40.5		 1ydbA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
PHE A 197
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
 1.41A 1ydbA-3uyqA:
40.5		 1ydbA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 142
PHE A 197
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
 0.97A 1ydbA-3uyqA:
40.5		 1ydbA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A 119
HIS A  96
VAL A 142
PHE A 197
THR A 198
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.35A 1ydbA-3uyqA:
40.5		 1ydbA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
 0.35A 1yddA-3uyqA:
40.9		 1yddA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.23A 1yddA-3uyqA:
40.9		 1yddA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 1z9yA-3uyqA:
40.9		 1z9yA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.34A 1zgfA-3uyqA:
41.0		 1zgfA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.18A 1zgfA-3uyqA:
41.0		 1zgfA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.46A 1zsbA-3uyqA:
41.4		 1zsbA-3uyqA:
58.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.41A 1zsbA-3uyqA:
41.4		 1zsbA-3uyqA:
58.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.28A 1zsbA-3uyqA:
41.4		 1zsbA-3uyqA:
58.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.71A 1zsbA-3uyqA:
41.4		 1zsbA-3uyqA:
58.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.39A 2aw1A-3uyqA:
40.6		 2aw1A-3uyqA:
58.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 4b4d FERREDOXIN-NADP
REDUCTASE
(Xanthomonas
citri) 		5 / 12 LEU A 205
ILE A 140
LEU A 192
THR A 193
LEU A 195
 None
None
None
CL  A1261 (-4.0A)
None
 0.73A 2bdmA-4b4dA:
undetectable		 2bdmA-4b4dA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		5 / 12 GLY A  16
ARG A  41
ASP A  66
ASN A  94
ALA A  95
 NDP  A 261 (-3.4A)
NDP  A 261 (-3.6A)
NDP  A 261 (-4.1A)
NDP  A 261 (-3.3A)
NDP  A 261 (-4.0A)
 1.02A 2bm9E-1ipfA:
5.9		 2bm9E-1ipfA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		5 / 12 GLY A  16
ARG A  41
ASP A  66
SER A  68
ALA A  95
 NDP  A 261 (-3.4A)
NDP  A 261 (-3.6A)
NDP  A 261 (-4.1A)
NDP  A 261 ( 4.9A)
NDP  A 261 (-4.0A)
 0.98A 2br4C-1ipfA:
5.8		 2br4C-1ipfA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 5e37 EF-HAND
DOMAIN-CONTAINING
THIOREDOXIN
(Chlamydomonas
reinhardtii) 		5 / 11 PHE A 261
ALA A 203
LEU A 220
ALA A 223
VAL A 229
 PHE  A 261 ( 1.3A)
ALA  A 203 ( 0.0A)
LEU  A 220 ( 0.6A)
ALA  A 223 ( 0.0A)
VAL  A 229 ( 0.6A)
 1.02A 2bxeB-5e37A:
undetectable		 2bxeB-5e37A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLU A 147
ASN A  98
ILE A 158
GLY A 181
ASN A 211
 SAH  A4261 (-2.7A)
None
None
None
None
 1.27A 2e7fB-1x1bA:
undetectable		 2e7fB-1x1bA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		6 / 12 ILE A  40
GLY A  41
GLY A  43
GLU A  85
ILE A 100
HIS A 105
 None
EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
None
EDO  A 261 ( 4.6A)
 1.02A 2fk8A-3egeA:
15.2		 2fk8A-3egeA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		6 / 12 ILE A  40
GLY A  41
GLY A  43
ILE A 100
ALA A 102
HIS A 105
 None
EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
EDO  A 261 ( 3.8A)
EDO  A 261 ( 4.6A)
 1.01A 2fk8A-3egeA:
15.2		 2fk8A-3egeA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.70A 2fqdA-5k8dB:
17.9		 2fqdA-5k8dB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.68A 2fqeA-5k8dB:
18.0		 2fqeA-5k8dB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.67A 2fqfA-5k8dB:
18.0		 2fqfA-5k8dB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.70A 2fqgA-5k8dB:
18.0		 2fqgA-5k8dB:
19.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.36A 2gehA-3uyqA:
40.9		 2gehA-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
GLY A  43
ALA A  84
GLU A  85
HIS A 105
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
None
EDO  A 261 ( 4.6A)
 0.92A 2gluA-3egeA:
17.3		 2gluA-3egeA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
ALA A  84
ALA A 102
HIS A 104
PHE A 106
 EDO  A 261 (-3.2A)
None
EDO  A 261 ( 3.8A)
None
None
 0.97A 2gluB-3egeA:
16.7		 2gluB-3egeA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		6 / 12 GLY A  41
GLY A  43
ALA A  84
ALA A 102
HIS A 105
PHE A 106
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
EDO  A 261 ( 3.8A)
EDO  A 261 ( 4.6A)
None
 0.47A 2gluB-3egeA:
16.7		 2gluB-3egeA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5oms CYTOCHROME P450
(Amycolatopsis
sp.
ATCC
39116) 		5 / 12 ALA A  79
ILE A  80
ALA A 295
LEU A 319
ILE A 292
 None
HEM  A 501 (-4.4A)
261  A 502 ( 3.9A)
None
HEM  A 501 ( 3.5A)
 0.95A 2h42B-5omsA:
undetectable		 2h42B-5omsA:
12.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  96
HIS A 119
VAL A 121
PHE A 130
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.46A 2h4nA-3uyqA:
41.3		 2h4nA-3uyqA:
58.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 THR A 216
LEU A 183
SER A 218
LEU A 118
HIS A 119
 None
None
None
None
ZN  A 261 (-3.2A)
 1.45A 2idkA-3uyqA:
undetectable
2idkB-3uyqA:
0.5
2idkC-3uyqA:
undetectable
2idkD-3uyqA:
0.2		 2idkA-3uyqA:
21.32
2idkB-3uyqA:
21.32
2idkC-3uyqA:
21.32
2idkD-3uyqA:
21.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
 0.28A 2it4A-3uyqA:
41.0		 2it4A-3uyqA:
55.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3a9l POLY-GAMMA-GLUTAMATE
HYDROLASE
(Bacillus
virus
NIT1) 		4 / 7 ASN A 154
GLY A 117
THR A 145
SER A  81
 None
None
None
PO4  A 261 (-2.5A)
 0.92A 2o5yH-3a9lA:
undetectable
2o5yL-3a9lA:
undetectable		 2o5yH-3a9lA:
19.51
2o5yL-3a9lA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 6 THR A   8
ASP A 120
THR A  17
ASP A  47
 None
None
ADP  A 261 (-3.5A)
None
 1.07A 2okcB-3r9jA:
undetectable		 2okcB-3r9jA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 LEU A 201
ILE A 205
GLY A 178
HIS A 150
 SAH  A4261 (-4.0A)
None
SAH  A4261 ( 4.2A)
SAH  A4261 (-3.6A)
 1.02A 2otfA-1x1bA:
undetectable		 2otfA-1x1bA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 177
GLY A 179
GLY A 181
LEU A 201
ILE A 228
 SAH  A4261 (-3.8A)
SAH  A4261 (-3.3A)
None
SAH  A4261 (-4.0A)
SAH  A4261 (-3.9A)
 0.78A 2oxtB-1x1bA:
8.2		 2oxtB-1x1bA:
21.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.38A 2pouA-3uyqA:
40.8		 2pouA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.21A 2pouA-3uyqA:
40.8		 2pouA-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 11 ASP A  58
HIS A  59
HIS A 110
ASP A 134
HIS A 173
 ZN  A 262 (-2.7A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
ZN  A 262 ( 2.4A)
ZN  A 262 (-3.3A)
 0.41A 2q0jB-1qh5A:
15.4		 2q0jB-1qh5A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 PRO A   3
THR A 112
ILE A 119
ASP A 121
PHE A 115
 None
None
None
None
IMD  A 261 (-4.5A)
 1.29A 2v95A-3qzyA:
undetectable		 2v95A-3qzyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3cjy PUTATIVE
THIOESTERASE
(Novosphingobium
aromaticivorans) 		5 / 10 PHE A  35
ALA A  38
ALA A 181
LEU A 239
VAL A 237
 None
None
None
None
GOL  A 261 ( 4.5A)
 1.24A 2wuzA-3cjyA:
undetectable		 2wuzA-3cjyA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3cjy PUTATIVE
THIOESTERASE
(Novosphingobium
aromaticivorans) 		5 / 10 PHE A  35
ALA A 181
LEU A 239
MET A 223
VAL A 237
 None
None
None
None
GOL  A 261 ( 4.5A)
 1.17A 2wuzA-3cjyA:
undetectable		 2wuzA-3cjyA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3cjy PUTATIVE
THIOESTERASE
(Novosphingobium
aromaticivorans) 		5 / 10 PHE A  35
ALA A  38
ALA A 181
LEU A 239
VAL A 237
 None
None
None
None
GOL  A 261 ( 4.5A)
 1.23A 2wuzB-3cjyA:
undetectable		 2wuzB-3cjyA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3cjy PUTATIVE
THIOESTERASE
(Novosphingobium
aromaticivorans) 		5 / 10 PHE A  35
ALA A 181
LEU A 239
MET A 223
VAL A 237
 None
None
None
None
GOL  A 261 ( 4.5A)
 1.16A 2wuzB-3cjyA:
undetectable		 2wuzB-3cjyA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3cjy PUTATIVE
THIOESTERASE
(Novosphingobium
aromaticivorans) 		5 / 10 TYR A 144
ALA A 181
LEU A 239
MET A 223
VAL A 237
 None
None
None
None
GOL  A 261 ( 4.5A)
 1.44A 2wuzB-3cjyA:
undetectable		 2wuzB-3cjyA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 GLY A 179
HIS A 150
ILE A 158
ASN A  98
 SAH  A4261 (-3.3A)
SAH  A4261 (-3.6A)
None
None
 0.94A 2x0pA-1x1bA:
undetectable		 2x0pA-1x1bA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3a9l POLY-GAMMA-GLUTAMATE
HYDROLASE
(Bacillus
virus
NIT1) 		3 / 3 GLU A 165
HIS A  78
GLU A  45
 PO4  A 261 (-3.2A)
PO4  A 261 (-3.9A)
ZN  A 251 ( 2.1A)
 0.79A 2x45B-3a9lA:
undetectable		 2x45B-3a9lA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3a9l POLY-GAMMA-GLUTAMATE
HYDROLASE
(Bacillus
virus
NIT1) 		3 / 3 GLU A 165
HIS A  78
GLU A  45
 PO4  A 261 (-3.2A)
PO4  A 261 (-3.9A)
ZN  A 251 ( 2.1A)
 0.81A 2x45C-3a9lA:
undetectable		 2x45C-3a9lA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1fxj UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Escherichia
coli) 		4 / 5 ARG A 237
ASP A 261
ILE A 279
GLU A 236
 ARG  A 237 ( 0.6A)
ASP  A 261 ( 0.6A)
ILE  A 279 ( 0.7A)
GLU  A 236 ( 0.6A)
 1.40A 2xrzA-1fxjA:
0.4
2xrzB-1fxjA:
0.3		 2xrzA-1fxjA:
20.79
2xrzB-1fxjA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.81A 2xxgA-5k8dB:
undetectable		 2xxgA-5k8dB:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 5 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.86A 2xxgC-5k8dB:
undetectable		 2xxgC-5k8dB:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3a9l POLY-GAMMA-GLUTAMATE
HYDROLASE
(Bacillus
virus
NIT1) 		5 / 12 GLY A  68
GLY A  42
ALA A  22
HIS A  78
LEU A  77
 None
None
None
PO4  A 261 (-3.9A)
None
 1.01A 2yqzA-3a9lA:
undetectable		 2yqzA-3a9lA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 2jc4 EXODEOXYRIBONUCLEASE
III
(Neisseria
meningitidis) 		4 / 6 TYR A  62
SER A  57
GLN A  39
ASP A  86
 2HP  A1261 ( 4.0A)
None
None
None
 1.31A 2zvjA-2jc4A:
undetectable		 2zvjA-2jc4A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 10 GLU A 244
GLY A 236
VAL A 217
LEU A 179
THR A  18
 None
None
ADP  A 261 (-4.4A)
None
ADP  A 261 (-3.8A)
 1.38A 3a3yA-3r9jA:
3.2		 3a3yA-3r9jA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PHE A 178
LEU A 171
ALA A  51
SER A  79
SER A 132
 None
None
None
None
C  A1261 (-2.8A)
 1.43A 3apvA-2x63A:
undetectable		 3apvA-2x63A:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.54A 3bl1A-3uyqA:
40.5		 3bl1A-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 6 ASP A  79
HIS A  59
HIS A  54
ASP A  58
HIS A  56
 None
ZN  A 262 ( 3.3A)
ZN  A 261 ( 3.4A)
ZN  A 262 (-2.7A)
ZN  A 261 ( 3.3A)
 1.36A 3c0zC-1qh5A:
undetectable		 3c0zC-1qh5A:
19.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
THR A 198
THR A 199
PRO A 201
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.49A 3cajA-3uyqA:
40.7		 3cajA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
THR A 198
THR A 199
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.35A 3cajA-3uyqA:
40.7		 3cajA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.31A 3cajA-3uyqA:
40.7		 3cajA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		8 / 8 HIS A 109
GLY A 136
ASN A 140
TRP A 166
TRP A 207
PHE A 211
TYR A 249
ARG A 251
 BEZ  A 261 (-3.7A)
BEZ  A 261 ( 3.7A)
BEZ  A 261 (-3.1A)
BEZ  A 261 (-3.7A)
BEZ  A 261 ( 4.6A)
BEZ  A 261 (-3.6A)
BEZ  A 261 (-4.2A)
BEZ  A 261 (-3.9A)
 0.00A 3ccfA-3ccfA:
41.2		 3ccfA-3ccfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		6 / 8 HIS A 109
GLY A 136
TRP A 110
PHE A 211
TYR A 249
ARG A 251
 BEZ  A 261 (-3.7A)
BEZ  A 261 ( 3.7A)
None
BEZ  A 261 (-3.6A)
BEZ  A 261 (-4.2A)
BEZ  A 261 (-3.9A)
 1.47A 3ccfA-3ccfA:
41.2		 3ccfA-3ccfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		8 / 8 HIS A 109
ASN A 140
ILE A 141
TRP A 166
TRP A 207
PHE A 211
TYR A 249
ARG A 251
 BEZ  A 261 (-3.7A)
BEZ  A 261 (-3.1A)
None
BEZ  A 261 (-3.7A)
BEZ  A 261 ( 4.6A)
BEZ  A 261 (-3.6A)
BEZ  A 261 (-4.2A)
BEZ  A 261 (-3.9A)
 0.67A 3ccfB-3ccfA:
35.6		 3ccfB-3ccfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 8 ILE A 144
TRP A 166
TRP A 207
PHE A 211
 None
BEZ  A 261 (-3.7A)
BEZ  A 261 ( 4.6A)
BEZ  A 261 (-3.6A)
 1.21A 3ccfB-3ccfA:
35.6		 3ccfB-3ccfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
 0.60A 3czvA-3uyqA:
41.5
3czvB-3uyqA:
41.5		 3czvA-3uyqA:
59.16
3czvB-3uyqA:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.51A 3czvB-3uyqA:
41.5		 3czvB-3uyqA:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.41A 3dazA-3uyqA:
41.4		 3dazA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.20A 3dazA-3uyqA:
41.4		 3dazA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.31A 3dazA-3uyqA:
41.4		 3dazA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.39A 3dazA-3uyqA:
41.4		 3dazA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.48A 3dc3A-3uyqA:
41.3		 3dc3A-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.42A 3dc3A-3uyqA:
41.3		 3dc3A-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.74A 3dc3A-3uyqA:
41.3		 3dc3A-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 3dcsA-3uyqA:
41.3		 3dcsA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.25A 3dcsA-3uyqA:
41.3		 3dcsA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.31A 3dcsA-3uyqA:
41.3		 3dcsA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.37A 3dcsA-3uyqA:
41.3		 3dcsA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
PRO A 201
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.50A 3dcwA-3uyqA:
41.4		 3dcwA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 3dcwA-3uyqA:
41.4		 3dcwA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
PRO A 201
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.53A 3dd0A-3uyqA:
41.2		 3dd0A-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 3dd0A-3uyqA:
41.2		 3dd0A-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 11 ASP A 230
ALA A 233
ASP A 234
ILE A 211
LEU A 218
 None
None
None
ADP  A 261 (-4.6A)
None
 0.94A 3em4U-3r9jA:
undetectable		 3em4U-3r9jA:
17.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
THR A 199
PRO A 201
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
None
None
 0.56A 3f4xA-3uyqA:
40.4		 3f4xA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 12 ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
ILE A 140
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.68A 3fw3A-3uyqA:
32.7		 3fw3A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  64
HIS A  96
ILE A 140
VAL A 121
THR A 199
 None
None
ZN  A 261 (-3.3A)
None
None
None
 1.47A 3fw3A-3uyqA:
32.7		 3fw3A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
ILE A 140
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.45A 3fw3A-3uyqA:
32.7		 3fw3A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
ILE A 140
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.56A 3fw3B-3uyqA:
32.5		 3fw3B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
ILE A 140
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.33A 3fw3B-3uyqA:
32.5		 3fw3B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 HIS A  94
HIS A  96
VAL A 121
ILE A 140
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
 1.33A 3fw3B-3uyqA:
32.5		 3fw3B-3uyqA:
34.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.63A 3g88A-3ccfA:
14.3		 3g88A-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.61A 3g88B-3ccfA:
14.3		 3g88B-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.59A 3g89A-3ccfA:
14.2		 3g89A-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.57A 3g89B-3ccfA:
14.2		 3g89B-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.62A 3g8bA-3ccfA:
14.2		 3g8bA-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.58A 3g8bB-3ccfA:
12.9		 3g8bB-3ccfA:
24.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 199
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
None
None
 0.46A 3hkuA-3uyqA:
41.0		 3hkuA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.26A 3hkuA-3uyqA:
41.0		 3hkuA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		3 / 3 GLU A 106
HIS A 119
THR A 198
 ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
ZN  A 261 ( 4.4A)
 0.17A 3hkuA-3uyqA:
41.0		 3hkuA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.41A 3hs4A-3uyqA:
41.3		 3hs4A-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.24A 3hs4A-3uyqA:
41.3		 3hs4A-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.29A 3hs4A-3uyqA:
41.3		 3hs4A-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3a9l POLY-GAMMA-GLUTAMATE
HYDROLASE
(Bacillus
virus
NIT1) 		5 / 9 ASP A 150
HIS A 103
GLU A 165
HIS A  40
ILE A 152
 None
ZN  A 251 ( 3.2A)
PO4  A 261 (-3.2A)
ZN  A 251 ( 3.2A)
None
 1.12A 3hy7A-3a9lA:
undetectable		 3hy7A-3a9lA:
18.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 3iaiA-3uyqA:
34.4		 3iaiA-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.14A 3iaiA-3uyqA:
34.4		 3iaiA-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.72A 3iaiA-3uyqA:
34.4		 3iaiA-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.43A 3iaiB-3uyqA:
34.4		 3iaiB-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.16A 3iaiB-3uyqA:
34.4		 3iaiB-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.71A 3iaiB-3uyqA:
34.4		 3iaiB-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.41A 3iaiC-3uyqA:
34.4		 3iaiC-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.15A 3iaiC-3uyqA:
34.4		 3iaiC-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.72A 3iaiC-3uyqA:
34.4		 3iaiC-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.43A 3iaiD-3uyqA:
34.4		 3iaiD-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.15A 3iaiD-3uyqA:
34.4		 3iaiD-3uyqA:
34.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.70A 3iaiD-3uyqA:
34.4		 3iaiD-3uyqA:
34.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 12 GLY A  77
ASP A 107
ASP A 166
ASP A 216
LEU A 190
 SAH  A 258 (-3.4A)
SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
EDO  A 261 (-2.7A)
SAH  A 258 (-4.2A)
 0.96A 3iv6B-3tosA:
8.5		 3iv6B-3tosA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		6 / 12 ILE A 153
GLY A 152
GLY A   8
PRO A  11
ALA A 163
TYR A  18
 C  A1261 (-4.3A)
None
C  A1261 (-3.0A)
C  A1261 (-4.8A)
None
None
 1.25A 3jayA-2x63A:
undetectable		 3jayA-2x63A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 12 ILE A 211
ARG A 251
SER A  19
ILE A  23
LEU A 246
 ADP  A 261 (-4.6A)
None
None
None
None
 1.09A 3k2hB-3r9jA:
3.9		 3k2hB-3r9jA:
19.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
PRO A 201
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
None
 0.48A 3kwaA-3uyqA:
40.3		 3kwaA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
VAL A 121
PHE A 130
THR A 199
 None
ZN  A 261 (-3.3A)
None
None
None
 1.10A 3kwaA-3uyqA:
40.3		 3kwaA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A 119
THR A 198
PRO A 200
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
ZN  A 261 ( 4.4A)
None
None
 1.33A 3kwaA-3uyqA:
40.3		 3kwaA-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2qiw PEP PHOSPHONOMUTASE
(Corynebacterium
glutamicum) 		5 / 12 ALA A 106
MET A   1
SER A  76
GLY A 143
ALA A 139
 None
None
None
GOL  A 261 (-3.9A)
None
 1.48A 3lbdA-2qiwA:
undetectable		 3lbdA-2qiwA:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 142
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 0.56A 3lxeA-3uyqA:
41.1		 3lxeA-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 142
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 0.55A 3lxeB-3uyqA:
41.2		 3lxeB-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
PRO A 201
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.47A 3mdzA-3uyqA:
39.7		 3mdzA-3uyqA:
47.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 3mdzA-3uyqA:
39.7		 3mdzA-3uyqA:
47.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.67A 3mdzA-3uyqA:
39.7		 3mdzA-3uyqA:
47.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 3ml5A-3uyqA:
41.0		 3ml5A-3uyqA:
50.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.22A 3ml5A-3uyqA:
41.0		 3ml5A-3uyqA:
50.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.21A 3ml5A-3uyqA:
41.0		 3ml5A-3uyqA:
50.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
GLY A  43
PRO A  63
ALA A  84
GLU A  85
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
EDO  A 261 ( 4.9A)
None
None
 0.75A 3mteB-3egeA:
10.3		 3mteB-3egeA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_1
(METHYLTRANSFERASE)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 9 GLY A  41
GLU A  62
PRO A  63
SER A  64
HIS A 105
 EDO  A 261 (-3.2A)
EDO  A 261 (-3.0A)
EDO  A 261 ( 4.9A)
None
EDO  A 261 ( 4.6A)
 0.94A 3ndiA-3egeA:
11.6		 3ndiA-3egeA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
GLY A  43
PRO A  63
ALA A  84
GLU A  85
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
EDO  A 261 ( 4.9A)
None
None
 0.71A 3p2kB-3egeA:
10.6		 3p2kB-3egeA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		5 / 12 TYR A  23
GLY A  24
GLU A  27
GLY A  16
VAL A  36
 None
None
None
NDP  A 261 (-3.4A)
None
 1.28A 3qowA-1ipfA:
4.5		 3qowA-1ipfA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 5 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.53A 3qpkA-5k8dB:
5.0		 3qpkA-5k8dB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.53A 3qpkB-5k8dB:
16.5		 3qpkB-5k8dB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 5vgm DIHYDROOROTASE
(Vibrio
cholerae) 		5 / 12 ASP A 246
HIS A  13
HIS A  15
ALA A 262
CYH A 217
 ZN  A 402 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.3A)
CSX  A 261 ( 3.6A)
None
 1.07A 3r2jC-5vgmA:
2.1		 3r2jC-5vgmA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ALA A 214
PHE A 215
TYR A 249
ILE A 141
LEU A 145
 None
None
BEZ  A 261 (-4.2A)
None
None
 0.99A 3rukA-3ccfA:
undetectable		 3rukA-3ccfA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 1szs 4-AMINOBUTYRATE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 VAL A 115
SER A 112
TYR A 138
GLY A 140
 None
PLP  A1261 ( 2.6A)
PMP  A1271 (-4.2A)
PLP  A1261 ( 3.9A)
 1.13A 3tj7C-1szsA:
0.0
3tj7D-1szsA:
0.0		 3tj7C-1szsA:
20.66
3tj7D-1szsA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		4 / 5 SER A 146
ILE A  21
TYR A 159
GLY A 190
 TNE  A 262 ( 2.9A)
NDP  A 261 (-4.1A)
TNE  A 262 ( 4.2A)
NDP  A 261 ( 4.9A)
 0.96A 3uboB-1ipfA:
6.4		 3uboB-1ipfA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		4 / 5 SER A 148
ILE A 144
TYR A 159
GLY A 190
 TNE  A 262 (-2.9A)
NDP  A 261 (-4.6A)
TNE  A 262 ( 4.2A)
NDP  A 261 ( 4.9A)
 0.99A 3uboB-1ipfA:
6.4		 3uboB-1ipfA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		4 / 5 SER A 151
ILE A  26
TYR A 164
GLY A 195
 NAP  A1261 ( 3.4A)
NAP  A1261 ( 3.7A)
NAP  A1261 ( 4.6A)
None
 1.04A 3uboB-2zatA:
7.1		 3uboB-2zatA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 TYR A 162
SER A 132
ASP A 242
ILE A 243
 C  A1261 (-4.2A)
C  A1261 (-2.8A)
None
None
 1.11A 3uj7B-2x63A:
undetectable		 3uj7B-2x63A:
24.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.35A 3v2jA-3uyqA:
41.3		 3v2jA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.21A 3v2jA-3uyqA:
41.3		 3v2jA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.29A 3v2jA-3uyqA:
41.3		 3v2jA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 130
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.33A 3v2mA-3uyqA:
41.3		 3v2mA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
 1.24A 3v2mA-3uyqA:
41.3		 3v2mA-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		5 / 12 GLY A  17
GLY A  22
GLU A  27
ALA A  62
LEU A  46
 NDP  A 261 ( 4.8A)
None
None
None
None
 1.18A 3vywA-1ipfA:
5.3		 3vywA-1ipfA:
21.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
ZN  A 261 ( 4.4A)
None
 0.48A 3w6hA-3uyqA:
40.9		 3w6hA-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 9 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 198
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
ZN  A 261 ( 4.4A)
None
 0.49A 3w6hB-3uyqA:
40.9		 3w6hB-3uyqA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.49A 3zncA-3uyqA:
31.6		 3zncA-3uyqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.32A 3zncA-3uyqA:
31.6		 3zncA-3uyqA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		5 / 11 ILE A  25
ILE A  21
GLY A  20
VAL A 250
GLY A 223
 None
NDP  A 261 (-4.1A)
NDP  A 261 (-3.5A)
None
None
 0.87A 4ac9B-1ipfA:
6.1
4ac9C-1ipfA:
4.3		 4ac9B-1ipfA:
19.14
4ac9C-1ipfA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		5 / 11 ILE A  30
ILE A  26
GLY A  25
VAL A 252
GLY A 225
 None
NAP  A1261 ( 3.7A)
NAP  A1261 ( 3.0A)
None
None
 1.01A 4ac9B-2zatA:
6.7
4ac9C-2zatA:
6.4		 4ac9B-2zatA:
18.88
4ac9C-2zatA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		4 / 7 GLY A 153
SER A 202
THR A 199
PHE A 201
 None
NAP  A1261 ( 3.4A)
NAP  A1261 ( 2.7A)
NAP  A1261 ( 4.9A)
 0.61A 4ac9C-2zatA:
6.4		 4ac9C-2zatA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ASP A 154
ILE A 153
GLY A 152
SER A  79
 None
C  A1261 (-4.3A)
None
None
 0.80A 4acbB-2x63A:
undetectable
4acbC-2x63A:
undetectable		 4acbB-2x63A:
20.49
4acbC-2x63A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 10 HIS A  54
HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.67A 4c1dB-1qh5A:
4.0		 4c1dB-1qh5A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 11 HIS A  54
HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.74A 4c1fA-1qh5A:
16.3
4c1fB-1qh5A:
15.3		 4c1fA-1qh5A:
24.82
4c1fB-1qh5A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 9 HIS A  54
HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.68A 4c1hA-1qh5A:
16.4		 4c1hA-1qh5A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 9 HIS A  56
ASP A  58
HIS A  54
GLY A 142
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 ( 3.4A)
GSH  A 463 (-3.5A)
ZN  A 262 (-3.3A)
 1.01A 4c1hA-1qh5A:
16.4		 4c1hA-1qh5A:
23.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.41A 4coqA-3uyqA:
31.3		 4coqA-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.21A 4coqA-3uyqA:
31.3		 4coqA-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4coqB-3uyqA:
31.3		 4coqB-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.20A 4coqB-3uyqA:
31.3		 4coqB-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 10 GLN A  92
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.35A 4e3hA-3uyqA:
40.9		 4e3hA-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
HIS B2005
MET B2010
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.6A)
CU  B2610 ( 3.9A)
 0.74A 4ef3A-5k8dB:
17.8		 4ef3A-5k8dB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.69A 4exsB-1qh5A:
2.3		 4exsB-1qh5A:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
PHE A 130
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.34A 4g0cA-3uyqA:
41.2		 4g0cA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.18A 4g0cA-3uyqA:
41.2		 4g0cA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.74A 4g0cA-3uyqA:
41.2		 4g0cA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.45A 4g7aA-3uyqA:
29.6		 4g7aA-3uyqA:
30.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4g7aA-3uyqA:
29.6		 4g7aA-3uyqA:
30.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.19A 4g7aA-3uyqA:
29.6		 4g7aA-3uyqA:
30.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.78A 4g7aA-3uyqA:
29.6		 4g7aA-3uyqA:
30.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.47A 4g7aB-3uyqA:
29.5		 4g7aB-3uyqA:
30.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.45A 4g7aB-3uyqA:
29.5		 4g7aB-3uyqA:
30.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.22A 4g7aB-3uyqA:
29.5		 4g7aB-3uyqA:
30.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.77A 4g7aB-3uyqA:
29.5		 4g7aB-3uyqA:
30.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		5 / 8 SER A 151
LEU A 174
LEU A 171
SER A 150
THR A 249
 NAP  A1261 ( 3.4A)
None
None
None
None
 1.33A 4ikjA-2zatA:
undetectable
4ikjB-2zatA:
undetectable		 4ikjA-2zatA:
19.54
4ikjB-2zatA:
19.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.37A 4k0sA-3uyqA:
41.2		 4k0sA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.18A 4k0sA-3uyqA:
41.2		 4k0sA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A  96
HIS A 119
LEU A 134
VAL A 142
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
 1.07A 4k0sA-3uyqA:
41.2		 4k0sA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.19A 4k0sA-3uyqA:
41.2		 4k0sA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
PRO A 201
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.50A 4k0zA-3uyqA:
41.2		 4k0zA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 4k0zA-3uyqA:
41.2		 4k0zA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  94
HIS A  96
HIS A 119
LEU A 134
VAL A 142
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
 1.02A 4k0zA-3uyqA:
41.2		 4k0zA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.35A 4k13A-3uyqA:
41.2		 4k13A-3uyqA:
57.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		4 / 5 LEU A 210
ARG A 221
PRO A 189
SER A 146
 TNE  A 262 (-4.9A)
None
NDP  A 261 ( 4.1A)
TNE  A 262 ( 2.9A)
 1.28A 4kmmB-1ipfA:
2.7		 4kmmB-1ipfA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
GLY A  43
SER A  64
ALA A  84
HIS A 105
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
None
EDO  A 261 ( 4.6A)
 0.91A 4krhA-3egeA:
16.2		 4krhA-3egeA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
GLY A  43
SER A  64
ALA A  84
HIS A 105
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
None
EDO  A 261 ( 4.6A)
 0.82A 4krhB-3egeA:
10.8		 4krhB-3egeA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 3a9l POLY-GAMMA-GLUTAMATE
HYDROLASE
(Bacillus
virus
NIT1) 		3 / 3 ARG A 143
LEU A 114
GLU A 165
 None
None
PO4  A 261 (-3.2A)
 0.59A 4l3gF-3a9lA:
undetectable		 4l3gF-3a9lA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 8 THR A 242
LEU A 179
VAL A 227
VAL A 217
 None
None
None
ADP  A 261 (-4.4A)
 1.07A 4l4bA-3r9jA:
undetectable		 4l4bA-3r9jA:
21.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.38A 4lu3A-3uyqA:
36.3		 4lu3A-3uyqA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.17A 4lu3A-3uyqA:
36.3		 4lu3A-3uyqA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
HIS A 119
LEU A 134
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
 1.08A 4lu3A-3uyqA:
36.3		 4lu3A-3uyqA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.73A 4lu3A-3uyqA:
36.3		 4lu3A-3uyqA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
PRO A 201
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
None
 0.54A 4m2rA-3uyqA:
41.4		 4m2rA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.25A 4m2rA-3uyqA:
41.4		 4m2rA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
 1.22A 4m2uA-3uyqA:
41.4		 4m2uA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		11 / 12 TRP A   5
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.47A 4m2uA-3uyqA:
41.4		 4m2uA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 TRP A  16
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
None
 1.43A 4m2uA-3uyqA:
41.4		 4m2uA-3uyqA:
58.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.25A 4m2vA-3uyqA:
41.4		 4m2vA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.38A 4m2vA-3uyqA:
41.4		 4m2vA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 4m2wA-3uyqA:
41.4		 4m2wA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.24A 4m2wA-3uyqA:
41.4		 4m2wA-3uyqA:
57.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
PHE A 130
THR A 198
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.43A 4n16A-3uyqA:
41.5		 4n16A-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 8 GLN A  92
HIS A  94
HIS A  96
PHE A 130
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.36A 4n16A-3uyqA:
41.5		 4n16A-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  16
PRO A  17
ILE A  65
THR A  66
LEU A 115
 CL  A 261 (-3.2A)
CL  A 261 ( 4.7A)
None
None
None
 1.06A 4n48A-3ucxA:
6.9		 4n48A-3ucxA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  16
PRO A  17
ILE A  65
THR A  66
LEU A 115
 CL  A 261 (-3.2A)
CL  A 261 ( 4.7A)
None
None
None
 1.01A 4n49A-3ucxA:
7.3		 4n49A-3ucxA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		4 / 8 LEU A  91
ASN A  93
LEU A  76
ILE A 117
 None
None
None
NDP  A 261 ( 4.1A)
 1.00A 4ok1A-1ipfA:
undetectable		 4ok1A-1ipfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 2vbf BRANCHED-CHAIN
ALPHA-KETOACID
DECARBOXYLASE
(Lactococcus
lactis) 		5 / 12 LEU A 261
GLY A 259
THR A 237
ILE A 211
VAL A 209
 LEU  A 261 ( 0.6A)
GLY  A 259 ( 0.0A)
THR  A 237 ( 0.8A)
ILE  A 211 ( 0.7A)
VAL  A 209 ( 0.6A)
 1.14A 4okwA-2vbfA:
undetectable		 4okwA-2vbfA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 CYH A  66
LEU A 225
HIS A 119
ALA A 116
LEU A 147
 None
None
ZN  A 261 (-3.2A)
None
None
 1.25A 4p65A-3uyqA:
undetectable
4p65B-3uyqA:
undetectable
4p65F-3uyqA:
undetectable
4p65H-3uyqA:
undetectable		 4p65A-3uyqA:
11.50
4p65B-3uyqA:
12.72
4p65F-3uyqA:
12.72
4p65H-3uyqA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 4bpt PHENYLALANINE-4-HYDR
OXYLASE (PAH)
(PHE-4-MONOOXYGENASE
)
(Legionella
pneumophila) 		4 / 6 PHE A  91
HIS A 122
HIS A 127
GLU A 167
 PEG  A1260 (-3.8A)
None
None
PEG  A1261 (-3.1A)
 0.80A 4pahA-4bptA:
28.4		 4pahA-4bptA:
29.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1yns E-1 ENZYME
(Homo
sapiens) 		5 / 12 ASP A 212
VAL A 213
SER A 154
GLY A  19
PHE A  32
 MG  A1258 (-2.6A)
None
HPO  A1261 (-2.3A)
MG  A1258 ( 4.4A)
HPO  A1261 (-4.6A)
 1.24A 4pevB-1ynsA:
4.2		 4pevB-1ynsA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 11 GLY A 177
GLY A 178
LEU A 201
ASP A 227
ILE A 244
 SAH  A4261 (-3.8A)
SAH  A4261 ( 4.2A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
None
 0.70A 4pghA-1x1bA:
18.2		 4pghA-1x1bA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 ASP A 175
GLY A 177
LEU A 201
ASP A 227
ILE A 244
 None
SAH  A4261 (-3.8A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
None
 0.65A 4pghB-1x1bA:
18.1		 4pghB-1x1bA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 177
GLY A 178
LEU A 201
ASP A 227
ILE A 244
 SAH  A4261 (-3.8A)
SAH  A4261 ( 4.2A)
SAH  A4261 (-4.0A)
SAH  A4261 (-2.9A)
None
 0.99A 4pghD-1x1bA:
23.6		 4pghD-1x1bA:
23.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
PHE A 130
THR A 198
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.38A 4pxxA-3uyqA:
41.5		 4pxxA-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 1zps PHOSPHORIBOSYL-AMP
CYCLOHYDROLASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 TYR A  58
HIS A  16
ASP A  87
ASP A  85
GLY A  88
 None
CD  A2611 ( 4.5A)
CD  A2606 (-2.2A)
CD  A2607 ( 2.5A)
None
 1.18A 4qa0A-1zpsA:
undetectable		 4qa0A-1zpsA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 1zps PHOSPHORIBOSYL-AMP
CYCLOHYDROLASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 TYR A  58
HIS A  16
ASP A  87
ASP A  85
GLY A  88
 None
CD  A2611 ( 4.5A)
CD  A2606 (-2.2A)
CD  A2607 ( 2.5A)
None
 1.20A 4qa0B-1zpsA:
undetectable		 4qa0B-1zpsA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 1zps PHOSPHORIBOSYL-AMP
CYCLOHYDROLASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 TYR A  58
HIS A  16
ASP A  87
ASP A  85
GLY A  88
 None
CD  A2611 ( 4.5A)
CD  A2606 (-2.2A)
CD  A2607 ( 2.5A)
None
 1.18A 4qa2A-1zpsA:
undetectable		 4qa2A-1zpsA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1zps PHOSPHORIBOSYL-AMP
CYCLOHYDROLASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 TYR A  58
HIS A  16
ASP A  87
ASP A  85
GLY A  88
 None
CD  A2611 ( 4.5A)
CD  A2606 (-2.2A)
CD  A2607 ( 2.5A)
None
 1.18A 4qa2B-1zpsA:
undetectable		 4qa2B-1zpsA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		6 / 12 GLY A  41
GLY A  43
SER A  64
MET A  67
ILE A 100
ALA A 102
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
EDO  A 261 ( 4.1A)
None
EDO  A 261 ( 3.8A)
 0.83A 4qtuB-3egeA:
15.8		 4qtuB-3egeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
GLY A  43
SER A  64
ILE A 100
ALA A 102
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
None
EDO  A 261 ( 3.8A)
 0.58A 4qtuD-3egeA:
16.4		 4qtuD-3egeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY
(Trichormus
variabilis) 		5 / 12 GLY A  41
GLY A  43
SER A  64
MET A  67
ILE A 100
 EDO  A 261 (-3.2A)
EDO  A 261 ( 3.9A)
None
EDO  A 261 ( 4.1A)
None
 0.79A 4qtuD-3egeA:
16.4		 4qtuD-3egeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1yns E-1 ENZYME
(Homo
sapiens) 		4 / 8 GLU A  36
VAL A  27
LEU A  31
GLY A 115
 None
HPO  A1261 ( 4.8A)
None
None
 0.89A 4r3aA-1ynsA:
undetectable		 4r3aA-1ynsA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 4bpt PHENYLALANINE-4-HYDR
OXYLASE (PAH)
(PHE-4-MONOOXYGENASE
)
(Legionella
pneumophila) 		5 / 12 HIS A 122
GLU A 123
HIS A 127
PHE A 162
GLU A 167
 None
None
None
None
PEG  A1261 (-3.1A)
 1.18A 4r7lA-4bptA:
undetectable		 4r7lA-4bptA:
18.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 HIS A  96
VAL A 121
VAL A 142
PHE A 197
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
 0.57A 4twlA-3uyqA:
28.3		 4twlA-3uyqA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 HIS A  96
VAL A 121
VAL A 142
PHE A 197
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
 0.50A 4twlB-3uyqA:
28.3		 4twlB-3uyqA:
32.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3ggd SAM-DEPENDENT
METHYLTRANSFERASE
(Trichormus
variabilis) 		4 / 7 GLY A 218
ARG A  48
ALA A 236
ILE A 161
 EDO  A 261 (-3.9A)
EDO  A 261 ( 3.8A)
None
EDO  A 255 (-4.5A)
 0.93A 4txnA-3ggdA:
undetectable		 4txnA-3ggdA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3ggd SAM-DEPENDENT
METHYLTRANSFERASE
(Trichormus
variabilis) 		4 / 7 GLY A 218
ARG A  48
ALA A 236
ILE A 161
 EDO  A 261 (-3.9A)
EDO  A 261 ( 3.8A)
None
EDO  A 255 (-4.5A)
 0.97A 4txnB-3ggdA:
undetectable		 4txnB-3ggdA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3ggd SAM-DEPENDENT
METHYLTRANSFERASE
(Trichormus
variabilis) 		4 / 7 GLY A 218
ARG A  48
ALA A 236
ILE A 161
 EDO  A 261 (-3.9A)
EDO  A 261 ( 3.8A)
None
EDO  A 255 (-4.5A)
 0.93A 4txnD-3ggdA:
undetectable		 4txnD-3ggdA:
20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4uovA-3uyqA:
31.1		 4uovA-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.29A 4uovA-3uyqA:
31.1		 4uovA-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.80A 4uovA-3uyqA:
31.1		 4uovA-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.42A 4uovB-3uyqA:
31.2		 4uovB-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.24A 4uovB-3uyqA:
31.2		 4uovB-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.80A 4uovB-3uyqA:
31.2		 4uovB-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.43A 4uovC-3uyqA:
31.1		 4uovC-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.29A 4uovC-3uyqA:
31.1		 4uovC-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.79A 4uovC-3uyqA:
31.1		 4uovC-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.43A 4uovD-3uyqA:
31.1		 4uovD-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.30A 4uovD-3uyqA:
31.1		 4uovD-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.80A 4uovD-3uyqA:
31.1		 4uovD-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.42A 4uovE-3uyqA:
31.2		 4uovE-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.29A 4uovE-3uyqA:
31.2		 4uovE-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.79A 4uovE-3uyqA:
31.2		 4uovE-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.43A 4uovF-3uyqA:
31.2		 4uovF-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.25A 4uovF-3uyqA:
31.2		 4uovF-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.79A 4uovF-3uyqA:
31.2		 4uovF-3uyqA:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 4uy8 TRYPTOPHANASE
(Escherichia
coli) 		4 / 4 ILE 7  15
ASN 7  17
ILE 7  19
VAL 7  20
 TRP  71002 (-3.3A)
TRP  71002 (-3.9A)
C  A2610 ( 3.9A)
TRP  71002 (-4.5A)
 0.00A 4uy87-4uy87:
undetectable		 4uy87-4uy87:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4x5sA-3uyqA:
29.5		 4x5sA-3uyqA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.25A 4x5sA-3uyqA:
29.5		 4x5sA-3uyqA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.74A 4x5sA-3uyqA:
29.5		 4x5sA-3uyqA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4x5sB-3uyqA:
29.5		 4x5sB-3uyqA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.25A 4x5sB-3uyqA:
29.5		 4x5sB-3uyqA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.74A 4x5sB-3uyqA:
29.5		 4x5sB-3uyqA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.47A 4xiwA-3uyqA:
25.8
4xiwH-3uyqA:
25.9		 4xiwA-3uyqA:
31.05
4xiwH-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.21A 4xiwA-3uyqA:
25.8
4xiwH-3uyqA:
25.9		 4xiwA-3uyqA:
31.05
4xiwH-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.69A 4xiwA-3uyqA:
25.8
4xiwH-3uyqA:
25.9		 4xiwA-3uyqA:
31.05
4xiwH-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.46A 4xiwB-3uyqA:
25.8
4xiwE-3uyqA:
26.0		 4xiwB-3uyqA:
31.05
4xiwE-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.70A 4xiwB-3uyqA:
25.8
4xiwE-3uyqA:
26.0		 4xiwB-3uyqA:
31.05
4xiwE-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.36A 4xiwC-3uyqA:
25.7		 4xiwC-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.47A 4xiwC-3uyqA:
25.7		 4xiwC-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.61A 4xiwC-3uyqA:
25.7		 4xiwC-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.41A 4xiwD-3uyqA:
26.1		 4xiwD-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4xiwD-3uyqA:
26.1		 4xiwD-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.16A 4xiwD-3uyqA:
26.1		 4xiwD-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.68A 4xiwD-3uyqA:
26.1		 4xiwD-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4xiwE-3uyqA:
26.0		 4xiwE-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.26A 4xiwE-3uyqA:
26.0		 4xiwE-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.75A 4xiwE-3uyqA:
26.0		 4xiwE-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.44A 4xiwF-3uyqA:
25.9		 4xiwF-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.19A 4xiwF-3uyqA:
25.9		 4xiwF-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.78A 4xiwF-3uyqA:
25.9		 4xiwF-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.52A 4xiwG-3uyqA:
25.8		 4xiwG-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.19A 4xiwG-3uyqA:
25.8		 4xiwG-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.84A 4xiwG-3uyqA:
25.8		 4xiwG-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 142
TRP A 208
 None
None
ZN  A 261 (-3.2A)
None
None
None
 1.43A 4xiwH-3uyqA:
25.9		 4xiwH-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.48A 4xiwH-3uyqA:
25.9		 4xiwH-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 142
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.21A 4xiwH-3uyqA:
25.9		 4xiwH-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.72A 4xiwH-3uyqA:
25.9		 4xiwH-3uyqA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.43A 4ygfA-3uyqA:
26.3		 4ygfA-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.50A 4ygfB-3uyqA:
26.0		 4ygfB-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.42A 4ygfC-3uyqA:
19.5		 4ygfC-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.46A 4ygfD-3uyqA:
11.5		 4ygfD-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 12 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.41A 4ygfE-3uyqA:
26.6		 4ygfE-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.36A 4ygfF-3uyqA:
26.3		 4ygfF-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.45A 4ygfG-3uyqA:
6.5		 4ygfG-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.40A 4ygfH-3uyqA:
26.3		 4ygfH-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.46A 4yhaA-3uyqA:
26.4		 4yhaA-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
 0.57A 4yhaB-3uyqA:
25.6		 4yhaB-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.44A 4yhaC-3uyqA:
26.7		 4yhaC-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.47A 4yhaD-3uyqA:
25.4		 4yhaD-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
PRO A 201
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.52A 4yhaE-3uyqA:
26.5		 4yhaE-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.51A 4yhaE-3uyqA:
26.5		 4yhaE-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.64A 4yhaF-3uyqA:
24.2		 4yhaF-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.49A 4yhaG-3uyqA:
25.9		 4yhaG-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.41A 4yhaH-3uyqA:
26.1		 4yhaH-3uyqA:
30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.70A 5a5zA-1qh5A:
4.7		 5a5zA-1qh5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		6 / 11 HIS A  54
HIS A  56
ASP A  58
HIS A  59
HIS A 110
ARG A 249
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
GSH  A 463 (-2.8A)
 0.78A 5ayaA-1qh5A:
15.7		 5ayaA-1qh5A:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		6 / 11 HIS A  54
HIS A  56
ASP A  58
HIS A  59
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.29A 5ayaA-1qh5A:
15.7		 5ayaA-1qh5A:
25.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
PRO A 201
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.55A 5c8iA-3uyqA:
41.4		 5c8iA-3uyqA:
58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.42A 5c8iA-3uyqA:
41.4		 5c8iA-3uyqA:
58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 6 GLU A 225
GLY A  13
ARG A 182
GLY A  15
 None
ADP  A 261 (-3.4A)
ADP  A 261 (-3.5A)
ADP  A 261 (-3.2A)
 0.84A 5cdnA-3r9jA:
undetectable
5cdnB-3r9jA:
3.2		 5cdnA-3r9jA:
21.58
5cdnB-3r9jA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 3zty MANNOSYL-3-PHOSPHOGL
YCERATE PHOSPHATASE
(Thermus
thermophilus) 		4 / 8 ASP A 202
ASP A   6
ASP A 206
ILE A  56
 GD  A 261 (-2.4A)
GD  A 261 ( 2.9A)
None
None
 1.05A 5cfsA-3ztyA:
undetectable		 5cfsA-3ztyA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4
(Sus
scrofa) 		3 / 3 HIS A  71
SER A  97
ASN A 123
 NAP  A1261 ( 3.6A)
None
None
 0.92A 5cprB-2zatA:
undetectable		 5cprB-2zatA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ghg FIBRINOGEN GAMMA
CHAIN
(Homo
sapiens) 		4 / 6 ARG C 247
ASP C 285
GLY C 284
ASP C 261
 ARG  C 247 ( 0.6A)
ASP  C 285 ( 0.6A)
GLY  C 284 ( 0.0A)
ASP  C 261 ( 0.6A)
 1.34A 5hp1A-3ghgC:
undetectable		 5hp1A-3ghgC:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		5 / 12 ILE A  21
VAL A  26
ALA A  12
LEU A  88
GLY A 139
 NDP  A 261 (-4.1A)
None
None
None
None
 0.98A 5igtA-1ipfA:
0.0		 5igtA-1ipfA:
24.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.34A 5jn8A-3uyqA:
32.5		 5jn8A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.40A 5jn8A-3uyqA:
32.5		 5jn8A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.38A 5jn8B-3uyqA:
32.9		 5jn8B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.12A 5jn8B-3uyqA:
32.9		 5jn8B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.80A 5jn8B-3uyqA:
32.9		 5jn8B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.35A 5jn8C-3uyqA:
32.2		 5jn8C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.12A 5jn8C-3uyqA:
32.2		 5jn8C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.41A 5jn8C-3uyqA:
32.2		 5jn8C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 5jn8D-3uyqA:
32.1		 5jn8D-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.78A 5jn8D-3uyqA:
32.1		 5jn8D-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.41A 5jn8D-3uyqA:
32.1		 5jn8D-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.29A 5jn9A-3uyqA:
32.5		 5jn9A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.15A 5jn9A-3uyqA:
32.5		 5jn9A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.44A 5jn9A-3uyqA:
32.5		 5jn9A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.37A 5jn9B-3uyqA:
32.9		 5jn9B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.29A 5jn9B-3uyqA:
32.9		 5jn9B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.40A 5jn9B-3uyqA:
32.9		 5jn9B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.29A 5jn9C-3uyqA:
32.3		 5jn9C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.12A 5jn9C-3uyqA:
32.3		 5jn9C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.30A 5jn9D-3uyqA:
32.1		 5jn9D-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
 1.23A 5jn9D-3uyqA:
32.1		 5jn9D-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.57A 5jnaA-3uyqA:
32.4		 5jnaA-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.79A 5jnaA-3uyqA:
32.4		 5jnaA-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.56A 5jnaB-3uyqA:
32.8		 5jnaB-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 11 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.56A 5jnaC-3uyqA:
32.1		 5jnaC-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.54A 5jnaD-3uyqA:
32.0		 5jnaD-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.35A 5jncA-3uyqA:
32.5		 5jncA-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.09A 5jncA-3uyqA:
32.5		 5jncA-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.3A)
ZN  A 261 ( 4.9A)
None
ZN  A 261 ( 4.4A)
None
 0.76A 5jncA-3uyqA:
32.5		 5jncA-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.38A 5jncB-3uyqA:
32.9		 5jncB-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.37A 5jncB-3uyqA:
32.9		 5jncB-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.31A 5jncC-3uyqA:
32.2		 5jncC-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.41A 5jncC-3uyqA:
32.2		 5jncC-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.34A 5jncD-3uyqA:
32.1		 5jncD-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.43A 5jncD-3uyqA:
32.1		 5jncD-3uyqA:
34.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  20
VAL A  51
THR A  52
ALA A  37
LEU A  36
 CL  A 261 (-3.8A)
None
None
None
None
 1.04A 5kocA-3ucxA:
5.4		 5kocA-3ucxA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 143
SER A 144
ASN A 194
ASP A 195
 None
None
None
SO4  A 261 ( 4.5A)
 1.50A 5kpcA-3ozbA:
undetectable		 5kpcA-3ozbA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASN A  68
ASP A  89
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.73A 5kpcB-3ccfA:
14.5		 5kpcB-3ccfA:
21.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.33A 5ku6A-3uyqA:
32.4		 5ku6A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.13A 5ku6A-3uyqA:
32.4		 5ku6A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.40A 5ku6A-3uyqA:
32.4		 5ku6A-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.36A 5ku6B-3uyqA:
32.9		 5ku6B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.39A 5ku6B-3uyqA:
32.9		 5ku6B-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.32A 5ku6C-3uyqA:
32.2		 5ku6C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 GLN A  92
HIS A  94
HIS A  96
VAL A 121
THR A 199
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
 1.14A 5ku6C-3uyqA:
32.2		 5ku6C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.43A 5ku6C-3uyqA:
32.2		 5ku6C-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
None
 0.31A 5ku6D-3uyqA:
32.1		 5ku6D-3uyqA:
34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 142
THR A 198
THR A 199
 ZN  A 261 (-3.2A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
 1.39A 5ku6D-3uyqA:
32.1		 5ku6D-3uyqA:
34.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 9 ILE A 194
PHE A 220
VAL A 134
THR A 131
ILE A 153
 None
None
None
C  A1261 (-3.0A)
C  A1261 (-4.3A)
 1.43A 5lg3C-2x63A:
undetectable		 5lg3C-2x63A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 9 ILE A 194
PHE A 220
VAL A 134
THR A 131
ILE A 153
 None
None
None
C  A1261 (-3.0A)
C  A1261 (-4.3A)
 1.47A 5lg3D-2x63A:
undetectable		 5lg3D-2x63A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		6 / 12 PHE A 215
LEU A 148
ALA A 212
PRO A 165
PHE A 211
ILE A 141
 None
None
None
None
BEZ  A 261 (-3.6A)
None
 1.46A 5ljeA-3ccfA:
undetectable		 5ljeA-3ccfA:
19.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 7 GLN A  92
HIS A  94
VAL A 121
PHE A 130
THR A 198
THR A 199
 None
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
 0.29A 5m78A-3uyqA:
41.1		 5m78A-3uyqA:
40.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 7 GLN A  92
HIS A  94
VAL A 121
PHE A 130
THR A 199
 None
ZN  A 261 (-3.3A)
None
None
None
 1.04A 5m78A-3uyqA:
41.1		 5m78A-3uyqA:
40.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		4 / 7 ASN A  47
LEU A  50
VAL A  64
SER A  40
 None
None
None
NDP  A 261 (-3.8A)
 1.05A 5m8rA-1ipfA:
0.0		 5m8rA-1ipfA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 HIS A 150
SER A 247
HIS A 290
LEU A 302
 SAH  A4261 (-3.6A)
None
None
None
 1.03A 5m8rB-1x1bA:
undetectable		 5m8rB-1x1bA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		4 / 8 ASN A  47
LEU A  50
VAL A  64
SER A  40
 None
None
None
NDP  A 261 (-3.8A)
 1.02A 5m8rC-1ipfA:
undetectable		 5m8rC-1ipfA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 HIS A 150
SER A 247
HIS A 290
LEU A 302
 SAH  A4261 (-3.6A)
None
None
None
 1.01A 5m8rD-1x1bA:
undetectable		 5m8rD-1x1bA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA504_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.63A 5mejA-5k8dB:
13.1		 5mejA-5k8dB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA504_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.61A 5mewA-5k8dB:
13.1		 5mewA-5k8dB:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA504_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.60A 5mhuA-5k8dB:
13.0		 5mhuA-5k8dB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA504_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.60A 5mhvA-5k8dB:
18.5		 5mhvA-5k8dB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.60A 5mhwA-5k8dB:
18.5		 5mhwA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.60A 5mhxA-5k8dB:
13.1		 5mhxA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.60A 5mhyA-5k8dB:
13.1		 5mhyA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.59A 5mhzA-5k8dB:
13.1		 5mhzA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.59A 5mi1A-5k8dB:
13.1		 5mi1A-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.59A 5mi2A-5k8dB:
13.1		 5mi2A-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.60A 5miaA-5k8dB:
13.1		 5miaA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.59A 5mibA-5k8dB:
18.5		 5mibA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.59A 5micA-5k8dB:
13.1		 5micA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.59A 5midA-5k8dB:
18.5		 5midA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.59A 5mieA-5k8dB:
13.1		 5mieA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA604_0
(LACCASE 2)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		4 / 4 HIS B1954
CYH B2000
ILE B2002
HIS B2005
 CU  B2610 (-3.0A)
CU  B2610 (-1.9A)
CU  B2610 (-3.3A)
CU  B2610 (-3.6A)
 0.58A 5migA-5k8dB:
13.1		 5migA-5k8dB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		3 / 3 THR A 199
HIS A  96
ASN A 243
 None
ZN  A 261 (-3.3A)
None
 0.98A 5n4tA-3uyqA:
undetectable		 5n4tA-3uyqA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 2k3v TETRAHEME CYTOCHROME
C-TYPE
(Shewanella
frigidimarina) 		3 / 3 HIS A  49
ASN A  48
ALA A  85
 HEM  A 261 (-3.2A)
None
HEM  A 261 ( 2.8A)
 0.81A 5n4tB-2k3vA:
undetectable		 5n4tB-2k3vA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		5 / 6 ASP A  43
ASP A  45
HIS A  91
HIS A 126
HIS A 207
 EDO  A 261 (-3.4A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.8A)
 0.76A 5ncdA-3hftA:
10.7
5ncdD-3hftA:
10.4		 5ncdA-3hftA:
24.41
5ncdD-3hftA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		5 / 6 ASP A  43
ASP A  45
HIS A  91
HIS A 126
HIS A 207
 EDO  A 261 (-3.4A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.8A)
 0.70A 5ncdB-3hftA:
10.8
5ncdC-3hftA:
10.8		 5ncdB-3hftA:
24.41
5ncdC-3hftA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		4 / 4 ASP A  43
HIS A  91
HIS A 126
HIS A 207
 EDO  A 261 (-3.4A)
ZN  A 257 ( 3.4A)
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.8A)
 0.75A 5ncdD-3hftA:
10.3		 5ncdD-3hftA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1x1b CRTF-RELATED PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 VAL A 208
GLU A 210
LEU A 201
ALA A 204
ARG A 140
 None
None
SAH  A4261 (-4.0A)
None
None
 1.27A 5nd4B-1x1bA:
undetectable		 5nd4B-1x1bA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		5 / 8 ASP A  43
ASP A  45
HIS A  91
HIS A 126
HIS A 207
 EDO  A 261 (-3.4A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.8A)
 0.72A 5nekB-3hftA:
10.9		 5nekB-3hftA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		5 / 8 ASP A  43
ASP A  45
HIS A  91
HIS A 126
HIS A 207
 EDO  A 261 (-3.4A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.8A)
 0.71A 5nekD-3hftA:
10.6		 5nekD-3hftA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		5 / 6 ASP A  43
ASP A  45
HIS A  91
HIS A 126
HIS A 207
 EDO  A 261 (-3.4A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.8A)
 0.76A 5nelA-3hftA:
10.8
5nelD-3hftA:
10.2		 5nelA-3hftA:
24.41
5nelD-3hftA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		4 / 6 ASP A  43
HIS A  91
HIS A 126
HIS A 207
 EDO  A 261 (-3.4A)
ZN  A 257 ( 3.4A)
ZN  A 257 ( 3.4A)
EDO  A 261 (-3.8A)
 0.74A 5nelB-3hftA:
10.7
5nelC-3hftA:
10.7		 5nelB-3hftA:
24.41
5nelC-3hftA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 10 HIS A  54
HIS A  56
HIS A  59
HIS A 110
ASP A 134
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
ZN  A 262 ( 2.4A)
 0.30A 5nzwA-1qh5A:
6.5		 5nzwA-1qh5A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		3 / 3 HIS A 207
ASP A  45
HIS A  91
 EDO  A 261 (-3.8A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
 0.74A 5oexB-3hftA:
undetectable		 5oexB-3hftA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		3 / 3 HIS A 207
ASP A  45
HIS A  91
 EDO  A 261 (-3.8A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
 0.72A 5oexC-3hftA:
undetectable		 5oexC-3hftA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3hft WBMS, POLYSACCHARIDE
DEACETYLASE INVOLVED
IN O-ANTIGEN
BIOSYNTHESIS
(Bordetella
bronchiseptica) 		3 / 3 HIS A 207
ASP A  45
HIS A  91
 EDO  A 261 (-3.8A)
ZN  A 257 (-2.1A)
ZN  A 257 ( 3.4A)
 0.72A 5oexD-3hftA:
undetectable		 5oexD-3hftA:
20.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 6 HIS A  94
HIS A 119
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.40A 5ogjA-3uyqA:
41.2		 5ogjA-3uyqA:
58.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 6 HIS A  94
HIS A 119
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.38A 5ogjB-3uyqA:
41.3		 5ogjB-3uyqA:
58.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		4 / 5 HIS A  94
HIS A 119
VAL A 142
THR A 198
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
 0.31A 5ohhA-3uyqA:
41.2		 5ohhA-3uyqA:
58.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		5 / 6 HIS A  94
HIS A 119
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.40A 5ohhB-3uyqA:
41.2		 5ohhB-3uyqA:
58.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50
(Geobacillus
stearothermophil
us) 		4 / 8 GLU A 261
VAL A 142
GLY A 245
LEU A 241
 GLU  A 261 ( 0.6A)
VAL  A 142 ( 0.4A)
GLY  A 245 ( 0.0A)
LEU  A 241 ( 0.6A)
 0.99A 5sxqA-2ogsA:
undetectable		 5sxqA-2ogsA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50
(Geobacillus
stearothermophil
us) 		4 / 8 GLU A 261
VAL A 142
GLY A 245
LEU A 241
 GLU  A 261 ( 0.6A)
VAL  A 142 ( 0.4A)
GLY  A 245 ( 0.0A)
LEU  A 241 ( 0.6A)
 1.00A 5sxtB-2ogsA:
undetectable		 5sxtB-2ogsA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50
(Geobacillus
stearothermophil
us) 		4 / 8 GLU A 261
VAL A 142
GLY A 245
LEU A 241
 GLU  A 261 ( 0.6A)
VAL  A 142 ( 0.4A)
GLY  A 245 ( 0.0A)
LEU  A 241 ( 0.6A)
 1.00A 5syjB-2ogsA:
undetectable		 5syjB-2ogsA:
22.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
PRO A 201
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.49A 5tt3A-3uyqA:
26.2		 5tt3A-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.42A 5tt3A-3uyqA:
26.2		 5tt3A-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.48A 5tt3B-3uyqA:
24.5		 5tt3B-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
PRO A 201
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.58A 5tt3C-3uyqA:
26.5		 5tt3C-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.36A 5tt3C-3uyqA:
26.5		 5tt3C-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.53A 5tt3E-3uyqA:
26.4		 5tt3E-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.47A 5tt3F-3uyqA:
25.8		 5tt3F-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		7 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 142
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
None
ZN  A 261 ( 4.4A)
None
 0.51A 5tt3G-3uyqA:
25.8		 5tt3G-3uyqA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
THR A 198
TRP A 208
 ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
ZN  A 261 (-3.2A)
None
ZN  A 261 ( 4.4A)
None
 0.38A 5tt3H-3uyqA:
25.8		 5tt3H-3uyqA:
30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 2jc4 EXODEOXYRIBONUCLEASE
III
(Neisseria
meningitidis) 		4 / 7 GLY A 145
TRP A 123
GLN A  88
TYR A 119
 None
None
2HP  A1261 ( 3.9A)
None
 1.18A 5vlmG-2jc4A:
undetectable		 5vlmG-2jc4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1yns E-1 ENZYME
(Homo
sapiens) 		5 / 11 GLY A 155
GLY A 115
GLN A 114
THR A 107
THR A 108
 HPO  A1261 ( 3.8A)
None
None
None
None
 1.24A 5x1bG-1ynsA:
0.0
5x1bN-1ynsA:
0.0
5x1bO-1ynsA:
0.0		 5x1bG-1ynsA:
13.79
5x1bN-1ynsA:
17.94
5x1bO-1ynsA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1ipf TROPINONE
REDUCTASE-II
(Datura
stramonium) 		5 / 9 ILE A 214
ASP A 251
LEU A 254
GLY A 190
ALA A 256
 None
None
None
NDP  A 261 ( 4.9A)
None
 1.42A 5x66C-1ipfA:
undetectable		 5x66C-1ipfA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		3 / 3 GLU A 106
TRP A 208
HIS A  94
 ZN  A 261 ( 4.9A)
None
ZN  A 261 (-3.3A)
 0.93A 5xipA-3uyqA:
undetectable		 5xipA-3uyqA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		3 / 3 GLU A 117
TRP A 208
HIS A  94
 None
None
ZN  A 261 (-3.3A)
 1.07A 5xipA-3uyqA:
undetectable		 5xipA-3uyqA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 LEU A 235
ILE A 144
ILE A 208
MET A 204
HIS A 109
 None
None
None
None
BEZ  A 261 (-3.7A)
 1.21A 5y2tB-3ccfA:
undetectable		 5y2tB-3ccfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 5oms CYTOCHROME P450
(Amycolatopsis
sp.
ATCC
39116) 		4 / 8 ILE A 196
LEU A 165
ALA A 246
LEU A 144
 None
None
261  A 502 ( 3.5A)
None
 0.81A 5y7pE-5omsA:
undetectable		 5y7pE-5omsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.75A 5zj8A-1qh5A:
15.8		 5zj8A-1qh5A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A 171
LEU A  54
ALA A  51
SER A  79
GLY A   8
 None
None
None
None
C  A1261 (-3.0A)
 0.94A 6b0iB-2x63A:
undetectable		 6b0iB-2x63A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3skd PUTATIVE
UNCHARACTERIZED
PROTEIN TTHB187
(Thermus
thermophilus) 		3 / 3 HIS A  24
HIS A  19
ARG A 218
 NI  A 261 (-3.5A)
None
None
 0.92A 6b58A-3skdA:
undetectable		 6b58A-3skdA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2uz0 TRIBUTYRIN ESTERASE
(Streptococcus
pneumoniae) 		3 / 3 LEU A 119
THR A  74
ASN A  73
 None
None
EDO  A1261 (-3.5A)
 0.68A 6baaE-2uz0A:
undetectable		 6baaE-2uz0A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2uz0 TRIBUTYRIN ESTERASE
(Streptococcus
pneumoniae) 		3 / 3 LEU A 119
THR A  74
ASN A  73
 None
None
EDO  A1261 (-3.5A)
 0.67A 6baaF-2uz0A:
undetectable		 6baaF-2uz0A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2uz0 TRIBUTYRIN ESTERASE
(Streptococcus
pneumoniae) 		3 / 3 LEU A 119
THR A  74
ASN A  73
 None
None
EDO  A1261 (-3.5A)
 0.68A 6baaG-2uz0A:
undetectable		 6baaG-2uz0A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2uz0 TRIBUTYRIN ESTERASE
(Streptococcus
pneumoniae) 		3 / 3 LEU A 119
THR A  74
ASN A  73
 None
None
EDO  A1261 (-3.5A)
 0.68A 6baaH-2uz0A:
undetectable		 6baaH-2uz0A:
10.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 TRP A   5
ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
PHE A 130
THR A 198
THR A 199
TRP A 208
 None
None
None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
ZN  A 261 ( 4.4A)
None
None
 0.73A 6bbsA-3uyqA:
33.4		 6bbsA-3uyqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 TRP A   5
HIS A  64
HIS A  94
THR A 198
THR A 199
TRP A 208
 None
None
ZN  A 261 (-3.3A)
ZN  A 261 ( 4.4A)
None
None
 1.40A 6bbsA-3uyqA:
33.4		 6bbsA-3uyqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 198
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
 1.22A 6bc9A-3uyqA:
41.3		 6bc9A-3uyqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 TRP A   5
ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 198
THR A 199
PRO A 201
 None
None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.56A 6bc9A-3uyqA:
41.3		 6bc9A-3uyqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		10 / 12 TRP A   5
ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
THR A 198
THR A 199
TRP A 208
 None
None
None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
ZN  A 261 ( 4.4A)
None
None
 0.50A 6bc9A-3uyqA:
41.3		 6bc9A-3uyqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		4 / 5 HIS A  64
GLU A 106
HIS A 119
VAL A 142
 None
ZN  A 261 ( 4.9A)
ZN  A 261 (-3.2A)
None
 0.44A 6bc9A-3uyqA:
41.3		 6bc9A-3uyqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
PRO A 201
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.52A 6bccA-3uyqA:
41.3		 6bccA-3uyqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3uyq CARBONIC ANHYDRASE 3
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 130
VAL A 142
THR A 198
THR A 199
TRP A 208
 None
ZN  A 261 (-3.3A)
ZN  A 261 (-3.3A)
None
None
None
ZN  A 261 ( 4.4A)
None
None
 0.35A 6bccA-3uyqA:
41.3		 6bccA-3uyqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2jc4 EXODEOXYRIBONUCLEASE
III
(Neisseria
meningitidis) 		3 / 3 GLN A  59
TYR A  62
ASN A  63
 None
2HP  A1261 ( 4.0A)
None
 0.56A 6dwdC-2jc4A:
undetectable		 6dwdC-2jc4A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION
(Homo
sapiens) 		3 / 3 HIS B2005
ARG B1917
ILE B1882
 CU  B2610 (-3.6A)
None
None
 0.80A 6fgdA-5k8dB:
undetectable		 6fgdA-5k8dB:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 4bpt PHENYLALANINE-4-HYDR
OXYLASE (PAH)
(PHE-4-MONOOXYGENASE
)
(Legionella
pneumophila) 		4 / 6 PRO A 118
HIS A 122
HIS A 127
GLU A 167
 None
None
None
PEG  A1261 (-3.1A)
 0.75A 6pahA-4bptA:
28.4		 6pahA-4bptA:
29.32