SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '23J'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		4 / 6 ASP A  79
HIS A  83
HIS A 212
HIS A  77
 MN  A 301 ( 2.5A)
23J  A 302 (-3.6A)
23J  A 302 (-4.0A)
MN  A 301 ( 3.3A)
 0.61A 5ncdA-4m8dA:
undetectable
5ncdD-4m8dA:
undetectable		 5ncdA-4m8dA:
23.02
5ncdD-4m8dA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		4 / 6 ASP A  79
HIS A  83
HIS A 212
HIS A  77
 MN  A 301 ( 2.5A)
23J  A 302 (-3.6A)
23J  A 302 (-4.0A)
MN  A 301 ( 3.3A)
 0.57A 5ncdB-4m8dA:
undetectable
5ncdC-4m8dA:
undetectable		 5ncdB-4m8dA:
23.02
5ncdC-4m8dA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		4 / 8 ASP A  79
HIS A  83
HIS A 212
HIS A  77
 MN  A 301 ( 2.5A)
23J  A 302 (-3.6A)
23J  A 302 (-4.0A)
MN  A 301 ( 3.3A)
 0.70A 5nekB-4m8dA:
undetectable		 5nekB-4m8dA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		4 / 8 ASP A  79
HIS A  83
HIS A 212
HIS A  77
 MN  A 301 ( 2.5A)
23J  A 302 (-3.6A)
23J  A 302 (-4.0A)
MN  A 301 ( 3.3A)
 0.66A 5nekD-4m8dA:
undetectable		 5nekD-4m8dA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		4 / 6 ASP A  79
HIS A  83
HIS A 212
HIS A  77
 MN  A 301 ( 2.5A)
23J  A 302 (-3.6A)
23J  A 302 (-4.0A)
MN  A 301 ( 3.3A)
 0.68A 5nelA-4m8dA:
undetectable
5nelD-4m8dA:
undetectable		 5nelA-4m8dA:
23.02
5nelD-4m8dA:
23.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
LEU A  35
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-4.8A)
None
None
None
23J  A 302 (-4.0A)
 1.38A 5nnaA-4m8dA:
39.4		 5nnaA-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
PRO A 169
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 1.39A 5nnaA-4m8dA:
39.4		 5nnaA-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		7 / 12 LEU A  35
HIS A  83
TRP A  84
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 23J  A 302 (-4.8A)
23J  A 302 (-3.6A)
None
None
None
None
23J  A 302 (-4.0A)
 1.45A 5nnaA-4m8dA:
39.4		 5nnaA-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		9 / 12 LEU A  37
HIS A  83
TRP A  84
PRO A 169
SER A 171
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-3.6A)
None
None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 0.33A 5nnaA-4m8dA:
39.4		 5nnaA-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
LEU A  35
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-4.8A)
None
None
None
23J  A 302 (-4.0A)
 1.35A 5nnaB-4m8dA:
39.4		 5nnaB-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
PRO A 169
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 1.38A 5nnaB-4m8dA:
39.4		 5nnaB-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		7 / 12 LEU A  35
HIS A  83
TRP A  84
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 23J  A 302 (-4.8A)
23J  A 302 (-3.6A)
None
None
None
None
23J  A 302 (-4.0A)
 1.46A 5nnaB-4m8dA:
39.4		 5nnaB-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		9 / 12 LEU A  37
HIS A  83
TRP A  84
PRO A 169
SER A 171
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-3.6A)
None
None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 0.38A 5nnaB-4m8dA:
39.4		 5nnaB-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
LEU A  35
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-4.8A)
None
None
None
23J  A 302 (-4.0A)
 1.33A 5nnaC-4m8dA:
39.5		 5nnaC-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
PRO A 169
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 1.37A 5nnaC-4m8dA:
39.5		 5nnaC-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		7 / 12 LEU A  35
HIS A  83
TRP A  84
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 23J  A 302 (-4.8A)
23J  A 302 (-3.6A)
None
None
None
None
23J  A 302 (-4.0A)
 1.43A 5nnaC-4m8dA:
39.5		 5nnaC-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		9 / 12 LEU A  37
HIS A  83
TRP A  84
PRO A 169
SER A 171
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-3.6A)
None
None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 0.35A 5nnaC-4m8dA:
39.5		 5nnaC-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
LEU A  35
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-4.8A)
None
None
None
23J  A 302 (-4.0A)
 1.43A 5nnaD-4m8dA:
39.1		 5nnaD-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		6 / 12 ILE A 195
PRO A 169
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 1.42A 5nnaD-4m8dA:
39.1		 5nnaD-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		7 / 12 LEU A  35
HIS A  83
TRP A  84
PRO A 169
ASP A 198
GLY A 200
HIS A 212
 23J  A 302 (-4.8A)
23J  A 302 (-3.6A)
None
None
None
None
23J  A 302 (-4.0A)
 1.50A 5nnaD-4m8dA:
39.1		 5nnaD-4m8dA:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 4m8d PUTATIVE
UNCHARACTERIZED
PROTEIN
(Labrenzia
aggregata) 		9 / 12 LEU A  37
HIS A  83
TRP A  84
PRO A 169
SER A 171
GLY A 196
ASP A 198
GLY A 200
HIS A 212
 None
23J  A 302 (-3.6A)
None
None
None
23J  A 302 (-3.5A)
None
None
23J  A 302 (-4.0A)
 0.37A 5nnaD-4m8dA:
39.1		 5nnaD-4m8dA:
49.44