SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ZZ'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P2F_A_ACTA653_0 (ACETYL-COENZYME A SYNTHETASE)	3kxw	SAFRAMYCIN MX1 SYNTHETASE B (Legionella pneumophila)	4 / 5	VAL A 451 THR A 452 VAL A 397 GLY A 398	1ZZ  A 589 (-4.4A) None None None	1.06A	2p2fA-3kxwA: 32.6	2p2fA-3kxwA: 24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P2F_A_ACTA653_0 (ACETYL-COENZYME A SYNTHETASE)	3pbk	FATTY ACYL-ADENYLATE LIGASE (Escherichia coli)	4 / 5	VAL A 456 THR A 457 VAL A 411 GLY A 412	1ZZ  A   1 (-4.1A) None None None	1.07A	2p2fA-3pbkA: 31.3	2p2fA-3pbkA: 25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P2F_B_ACTB653_0 (ACETYL-COENZYME A SYNTHETASE)	3pbk	FATTY ACYL-ADENYLATE LIGASE (Escherichia coli)	4 / 4	VAL A 456 THR A 457 VAL A 411 GLY A 412	1ZZ  A   1 (-4.1A) None None None	1.07A	2p2fB-3pbkA: 26.4	2p2fB-3pbkA: 25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QMZ_B_LDPB502_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE)	3kxw	SAFRAMYCIN MX1 SYNTHETASE B (Legionella pneumophila)	4 / 5	GLN A 171 PHE A 169 PHE A  80 GLY A 223	None None None 1ZZ  A 589 (-3.8A)	1.12A	2qmzA-3kxwA: 3.3 2qmzB-3kxwA: 3.7	2qmzA-3kxwA: 16.95 2qmzB-3kxwA: 16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	3kxw	SAFRAMYCIN MX1 SYNTHETASE B (Legionella pneumophila)	5 / 12	ASP A 440 VAL A 451 THR A 335 VAL A 334 ASP A 218	1ZZ  A 589 (-2.8A) 1ZZ  A 589 (-4.4A) None None 1ZZ  A 589 (-2.5A)	0.97A	2x0yA-3kxwA: undetectable	2x0yA-3kxwA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGP_A_PCFA1213_0 (WNT INHIBITORY FACTOR 1)	3pbk	FATTY ACYL-ADENYLATE LIGASE (Escherichia coli)	5 / 12	LEU A 215 ILE A 208 LEU A 344 ILE A 213 VAL A 247	None 1ZZ  A   1 (-4.5A) 1ZZ  A   1 (-4.1A) 1ZZ  A   1 ( 4.8A) None	1.07A	2ygpA-3pbkA: undetectable	2ygpA-3pbkA: 15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9T_C_BEZC264_0 (ECHA1_1)	3kxw	SAFRAMYCIN MX1 SYNTHETASE B (Legionella pneumophila)	4 / 5	ALA A 268 GLU A 534 GLU A 297 MET A 219	None None None 1ZZ  A 589 ( 3.9A)	1.09A	3r9tC-3kxwA: undetectable	3r9tC-3kxwA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_A_ACTA504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	3kxw	SAFRAMYCIN MX1 SYNTHETASE B (Legionella pneumophila)	3 / 3	THR A 438 VAL A 402 GLU A 329	None None 1ZZ  A 589 ( 4.9A)	0.69A	3v4tA-3kxwA: 0.0 3v4tD-3kxwA: undetectable	3v4tA-3kxwA: 21.30 3v4tD-3kxwA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW7_A_VPXA2001_1 (PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME)	3kxw	SAFRAMYCIN MX1 SYNTHETASE B (Legionella pneumophila)	5 / 12	TYR A  41 LEU A 332 LEU A  84 LEU A  11 ALA A  90	None 1ZZ  A 589 (-4.6A) None None None	1.17A	3vw7A-3kxwA: undetectable	3vw7A-3kxwA: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQT_A_TESA1000_1 (ANDROGEN RECEPTOR)	3kxw	SAFRAMYCIN MX1 SYNTHETASE B (Legionella pneumophila)	5 / 12	LEU A 332 LEU A 333 ASN A 193 MET A 203 THR A 227	1ZZ  A 589 (-4.6A) 1ZZ  A 589 ( 4.2A) None None None	1.41A	3zqtA-3kxwA: undetectable	3zqtA-3kxwA: 19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_B_P06B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	3pbk	FATTY ACYL-ADENYLATE LIGASE (Escherichia coli)	4 / 7	ILE A 213 GLY A 212 LEU A  23 PHE A  20	1ZZ  A   1 ( 4.8A) None None None	0.78A	5hieB-3pbkA: undetectable	5hieB-3pbkA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B50_A_OAQA302_0 (SULFOTRANSFERASE OXAMNIQUINE RESISTANCE PROTEIN)	3pbk	FATTY ACYL-ADENYLATE LIGASE (Escherichia coli)	5 / 12	LEU A 245 VAL A 303 VAL A 273 PHE A 236 MET A 334	None None None 1ZZ  A   1 ( 4.3A) None	1.43A	6b50A-3pbkA: undetectable	6b50A-3pbkA: 17.58