SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1YA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 4lxy WLARD, A SUGAR
3N-FORMYL
TRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ARG A 192
PRO A 112
SER A 120
GLY A 105
 1YA  A 301 (-4.3A)
None
None
None
 1.13A 2qd3A-4lxyA:
2.8		 2qd3A-4lxyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4lxy WLARD, A SUGAR
3N-FORMYL
TRANSFERASE
(Campylobacter
jejuni) 		4 / 8 GLU A  85
ASN A  86
ASN A 129
ILE A 127
 None
None
None
1YA  A 301 (-4.3A)
 1.31A 3kp6A-4lxyA:
undetectable
3kp6B-4lxyA:
undetectable		 3kp6A-4lxyA:
21.66
3kp6B-4lxyA:
21.66