SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1TA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ARG A  80
MET A 115
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.45A 1a28A-5ufsA:
37.7		 1a28A-5ufsA:
58.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ARG A  80
MET A 115
CYH A 205
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.51A 1a28B-5ufsA:
37.2		 1a28B-5ufsA:
58.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
LEU A  32
LEU A  77
ARG A  80
MET A 108
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.01A 1g50B-5ufsA:
27.4		 1g50B-5ufsA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
GLN A  39
TRP A  69
MET A  70
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.0A)
 1.29A 1gs4A-5ufsA:
35.3		 1gs4A-5ufsA:
55.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
GLY A  36
GLN A  39
MET A 108
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-4.0A)
 0.89A 1gs4A-5ufsA:
35.3		 1gs4A-5ufsA:
55.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLY A  36
GLN A  39
TRP A  69
MET A  70
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.0A)
 0.75A 1gs4A-5ufsA:
35.3		 1gs4A-5ufsA:
55.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
MET A 115
CYH A 205
THR A 208
PHE A 218
LEU A 222
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
None
 0.48A 1m2zA-5ufsA:
38.8		 1m2zA-5ufsA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLY A  37
GLN A  39
TRP A  69
MET A  70
CYH A 205
THR A 208
PHE A 218
LEU A 222
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
None
 0.92A 1m2zA-5ufsA:
38.8		 1m2zA-5ufsA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
CYH A 205
THR A 208
PHE A 218
LEU A 222
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
None
 0.47A 1m2zA-5ufsA:
38.8		 1m2zA-5ufsA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 ASN A  33
GLY A  37
GLN A  39
MET A  70
CYH A 205
THR A 208
PHE A 218
LEU A 222
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
None
 0.93A 1m2zD-5ufsA:
38.6		 1m2zD-5ufsA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
MET A  70
ARG A  80
MET A 115
CYH A 205
THR A 208
PHE A 218
LEU A 222
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
None
 0.53A 1m2zD-5ufsA:
38.6		 1m2zD-5ufsA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
VAL A  40
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.5A)
 0.93A 1nhzA-5ufsA:
31.9		 1nhzA-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
GLY A  36
GLN A  39
VAL A  40
MET A  73
LEU A  77
ARG A  80
MET A 115
LEU A 201
 1TA  A 301 (-3.5A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 0.58A 1nhzA-5ufsA:
31.9		 1nhzA-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 VAL A  40
MET A  73
LEU A  77
ARG A  80
GLN A 111
MET A 115
 None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 2.8A)
 1.31A 1nhzA-5ufsA:
31.9		 1nhzA-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
ASN A  33
LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
MET A 115
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
 0.59A 1p93A-5ufsA:
37.0		 1p93A-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
MET A  70
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
 0.79A 1p93A-5ufsA:
37.0		 1p93A-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
GLY A  36
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.45A 1p93B-5ufsA:
37.1		 1p93B-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
MET A  70
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.02A 1p93B-5ufsA:
37.1		 1p93B-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 MET A  29
ASN A  33
GLY A  36
MET A  70
CYH A 205
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-4.0A)
 0.80A 1p93B-5ufsA:
37.1		 1p93B-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
GLY A  36
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
LEU A 201
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.62A 1p93C-5ufsA:
36.7		 1p93C-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  37
MET A  70
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 1.11A 1p93C-5ufsA:
36.7		 1p93C-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 GLN A  39
MET A  70
LEU A  77
ARG A  80
GLN A 111
MET A 115
CYH A 205
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 1.42A 1p93C-5ufsA:
36.7		 1p93C-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 MET A  29
ASN A  33
GLY A  36
MET A  70
LEU A 201
CYH A 205
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
 0.88A 1p93C-5ufsA:
36.7		 1p93C-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
GLY A  36
GLN A  39
MET A  70
ARG A  80
PHE A  92
MET A 115
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.56A 1p93D-5ufsA:
36.8		 1p93D-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
MET A  70
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.05A 1p93D-5ufsA:
36.8		 1p93D-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
MET A  70
CYH A 205
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-4.0A)
 0.72A 1p93D-5ufsA:
36.8		 1p93D-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 5 LEU A  32
TRP A  69
MET A  73
LEU A  77
 1TA  A 301 (-3.5A)
None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
 0.43A 1p93D-5ufsA:
36.8		 1p93D-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 5 TRP A  69
MET A  73
LEU A  77
GLN A 111
 None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
None
 1.17A 1p93D-5ufsA:
36.8		 1p93D-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A  73
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 2.8A)
 0.80A 1sqnA-5ufsA:
37.2		 1sqnA-5ufsA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A 115
CYH A 205
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 0.48A 1sqnA-5ufsA:
37.2		 1sqnA-5ufsA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A 115
LEU A 201
CYH A 205
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
 0.52A 1sqnB-5ufsA:
37.1		 1sqnB-5ufsA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
LEU A  35
GLN A  39
MET A  70
MET A  73
MET A 115
LEU A 201
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 0.86A 1sqnB-5ufsA:
37.1		 1sqnB-5ufsA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
MET A 108
LEU A  77
MET A 115
LEU A  90
 1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 ( 2.8A)
None
 0.89A 1sqnB-5ufsA:
37.1		 1sqnB-5ufsA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 ASN A  33
LEU A  35
GLN A  39
LEU A  77
ARG A  80
MET A 108
MET A 115
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
 1.01A 1ya3A-5ufsA:
35.5		 1ya3A-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.46A 1ya3A-5ufsA:
35.5		 1ya3A-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  28
LEU A  35
GLN A  39
LEU A  77
ARG A  80
MET A 108
MET A 115
 None
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
 1.44A 1ya3A-5ufsA:
35.5		 1ya3A-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 ASN A  33
GLN A  39
MET A  70
LEU A  77
ARG A  80
LEU A 201
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.38A 1ya3B-5ufsA:
35.4		 1ya3B-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  90
LEU A 201
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 1.28A 1ya3B-5ufsA:
35.4		 1ya3B-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
LEU A  35
ARG A  80
MET A 108
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
 1.12A 1ya3C-5ufsA:
35.3		 1ya3C-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ARG A  80
LEU A 201
CYH A 205
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.40A 1ya3C-5ufsA:
35.3		 1ya3C-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 GLY A  37
GLN A  39
MET A  70
MET A  73
ARG A  80
ILE A 226
 None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
None
 1.08A 1z95A-5ufsA:
34.5		 1z95A-5ufsA:
55.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  70
MET A  73
ARG A  80
ILE A 226
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
None
 0.83A 1z95A-5ufsA:
34.5		 1z95A-5ufsA:
55.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 10 ASN A  33
GLN A  39
LEU A  77
ARG A  80
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.48A 1zucA-5ufsA:
37.6		 1zucA-5ufsA:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
THR A 208
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.68A 1zucB-5ufsA:
37.0		 1zucB-5ufsA:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  32
ASN A  33
LEU A  90
THR A 208
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.28A 1zucB-5ufsA:
37.0		 1zucB-5ufsA:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLN A  39
MET A  73
LEU A  77
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 0.96A 1zucB-5ufsA:
37.0		 1zucB-5ufsA:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
LEU A  35
GLN A  39
LEU A  77
ARG A  80
MET A 108
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
 1.07A 2aa5A-5ufsA:
36.4		 2aa5A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.49A 2aa5A-5ufsA:
36.4		 2aa5A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  35
ARG A  80
MET A 108
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
 1.06A 2aa5B-5ufsA:
36.5		 2aa5B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.41A 2aa5B-5ufsA:
36.5		 2aa5B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
LEU A  77
ARG A  80
MET A 108
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
 0.92A 2aa6A-5ufsA:
36.8		 2aa6A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
CYH A 205
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.40A 2aa6A-5ufsA:
36.8		 2aa6A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  35
ARG A  80
MET A 108
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
 0.97A 2aa6B-5ufsA:
36.6		 2aa6B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
LEU A 201
CYH A 205
THR A 208
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.43A 2aa6B-5ufsA:
36.6		 2aa6B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
GLN A  39
ARG A  80
PHE A  92
MET A 108
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.09A 2ab2A-5ufsA:
36.7		 2ab2A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLN A  39
MET A  70
ARG A  80
PHE A  92
MET A 115
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.53A 2ab2A-5ufsA:
36.7		 2ab2A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  28
GLN A  39
ARG A  80
PHE A  92
MET A 115
 None
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
 1.49A 2ab2A-5ufsA:
36.7		 2ab2A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 6 LEU A  32
LEU A  35
LEU A  77
CYH A 112
LEU A 201
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.4A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.8A)
 0.40A 2ab2A-5ufsA:
36.7		 2ab2A-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
GLN A  39
ARG A  80
PHE A  92
MET A 108
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.09A 2ab2B-5ufsA:
36.5		 2ab2B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLN A  39
MET A  70
ARG A  80
PHE A  92
MET A 115
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.55A 2ab2B-5ufsA:
36.5		 2ab2B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  28
GLN A  39
ARG A  80
PHE A  92
MET A 115
 None
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
 1.48A 2ab2B-5ufsA:
36.5		 2ab2B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 5 LEU A  32
LEU A  35
LEU A  77
CYH A 112
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.4A)
1TA  A 301 ( 3.6A)
 0.30A 2ab2B-5ufsA:
36.5		 2ab2B-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
LEU A  35
TRP A  69
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.83A 2am9A-5ufsA:
35.8		 2am9A-5ufsA:
52.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
TRP A  69
MET A  70
MET A  73
ARG A  80
LEU A 201
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
 0.82A 2am9A-5ufsA:
35.8		 2am9A-5ufsA:
52.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 GLN A  39
TRP A  69
MET A  70
MET A  73
ARG A  80
LEU A 201
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
 0.98A 2am9A-5ufsA:
35.8		 2am9A-5ufsA:
52.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  35
GLN A  39
TRP A  69
MET A  70
MET A  73
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 1.04A 2am9A-5ufsA:
35.8		 2am9A-5ufsA:
52.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 ASN A  33
LEU A  35
GLN A  39
LEU A  77
ARG A  80
MET A 108
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.05A 2oaxA-5ufsA:
35.2		 2oaxA-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.53A 2oaxA-5ufsA:
35.2		 2oaxA-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
LEU A  90
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.18A 2oaxA-5ufsA:
35.2		 2oaxA-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.45A 2oaxB-5ufsA:
35.3		 2oaxB-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  90
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.15A 2oaxB-5ufsA:
35.3		 2oaxB-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
GLN A  39
LEU A  77
ARG A  80
MET A 108
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.16A 2oaxC-5ufsA:
34.4		 2oaxC-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLN A  39
TRP A  69
MET A  70
LEU A  77
ARG A  80
LEU A 201
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.46A 2oaxC-5ufsA:
34.4		 2oaxC-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  90
LEU A 201
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.27A 2oaxC-5ufsA:
34.4		 2oaxC-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
LEU A  35
GLN A  39
LEU A  77
ARG A  80
MET A 108
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-4.0A)
 1.10A 2oaxD-5ufsA:
35.8		 2oaxD-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
LEU A  35
GLN A  39
TRP A  69
MET A  70
LEU A  77
ARG A  80
LEU A 201
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-4.0A)
 0.48A 2oaxD-5ufsA:
35.8		 2oaxD-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
LEU A  35
GLN A  39
ARG A  80
MET A 108
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-4.0A)
 1.00A 2oaxE-5ufsA:
35.6		 2oaxE-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
LEU A 201
CYH A 205
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-4.0A)
 0.57A 2oaxE-5ufsA:
35.6		 2oaxE-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  90
LEU A 201
CYH A 205
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-4.0A)
 1.13A 2oaxE-5ufsA:
35.6		 2oaxE-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 ASN A  33
LEU A  35
GLN A  39
TRP A  69
MET A  70
LEU A  77
ARG A  80
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.52A 2oaxF-5ufsA:
35.7		 2oaxF-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  90
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.13A 2oaxF-5ufsA:
35.7		 2oaxF-5ufsA:
62.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLY A  36
GLN A  39
ARG A  80
MET A 108
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-4.0A)
 1.09A 2oz7A-5ufsA:
34.4		 2oz7A-5ufsA:
54.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 6 MET A  70
MET A  73
MET A 115
LEU A 201
 1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 0.83A 2oz7A-5ufsA:
34.4		 2oz7A-5ufsA:
54.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 6 TRP A  69
MET A  70
MET A 115
LEU A 201
 None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 1.35A 2oz7A-5ufsA:
34.4		 2oz7A-5ufsA:
54.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
ARG A  80
MET A 108
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.07A 2q7iA-5ufsA:
34.9		 2q7iA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.84A 2q7iA-5ufsA:
34.9		 2q7iA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  35
GLN A  39
ARG A  80
MET A 108
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.17A 2q7jA-5ufsA:
35.6		 2q7jA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
LEU A  35
GLN A  39
TRP A  69
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.85A 2q7jA-5ufsA:
35.6		 2q7jA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  28
LEU A  35
GLN A  39
ARG A  80
MET A 108
 None
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.47A 2q7jA-5ufsA:
35.6		 2q7jA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLN A  39
MET A  70
ARG A  80
LEU A 201
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
 0.70A 2q7kA-5ufsA:
35.1		 2q7kA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
ARG A  80
MET A 108
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.05A 2q7kA-5ufsA:
35.1		 2q7kA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
 0.75A 2q7kA-5ufsA:
35.1		 2q7kA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  37
GLN A  39
TRP A  69
MET A  70
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
 1.30A 2q7lA-5ufsA:
35.5		 2q7lA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
GLY A  36
GLN A  39
ARG A  80
MET A 108
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.02A 2q7lA-5ufsA:
35.5		 2q7lA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
 0.73A 2q7lA-5ufsA:
35.5		 2q7lA-5ufsA:
53.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 GLY A  37
GLN A  39
TRP A  69
MET A  70
CYH A 205
 None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
 1.04A 2w8yA-5ufsA:
37.1		 2w8yA-5ufsA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  35
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
CYH A 205
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.6A)
 0.42A 2w8yA-5ufsA:
37.1		 2w8yA-5ufsA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  35
GLY A  36
GLN A  39
TRP A  69
MET A  70
MET A  73
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.79A 2w8yA-5ufsA:
37.1		 2w8yA-5ufsA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ARG A  80
MET A 115
CYH A 205
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 0.53A 2w8yB-5ufsA:
37.6		 2w8yB-5ufsA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A  73
ARG A  80
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
 0.79A 2w8yB-5ufsA:
37.6		 2w8yB-5ufsA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  37
GLN A  39
MET A  70
MET A  73
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
 1.43A 2yhdA-5ufsA:
35.1		 2yhdA-5ufsA:
54.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
LEU A  35
GLY A  36
GLN A  39
ARG A  80
MET A 108
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.04A 2yhdA-5ufsA:
35.1		 2yhdA-5ufsA:
54.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
LEU A  35
GLY A  36
GLN A  39
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.79A 2yhdA-5ufsA:
35.1		 2yhdA-5ufsA:
54.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
MET A  70
MET A  73
ARG A  80
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.0A)
 0.89A 2yloA-5ufsA:
35.2		 2yloA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLN A  39
MET A  70
MET A  73
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 1.01A 2yloA-5ufsA:
35.2		 2yloA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 11 ASN A  33
GLN A  39
MET A  70
MET A  73
ARG A  80
LEU A 201
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
 0.82A 2ylpA-5ufsA:
35.5		 2ylpA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 11 ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.85A 2ylpA-5ufsA:
35.5		 2ylpA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLQ_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 11 ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.84A 2ylqA-5ufsA:
35.5		 2ylqA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
GLY A  37
GLN A  39
MET A  70
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.07A 3cldA-5ufsA:
38.2		 3cldA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		12 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
MET A  70
LEU A  77
ARG A  80
CYH A 112
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.41A 3cldA-5ufsA:
38.2		 3cldA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 MET A  29
ASN A  33
LEU A  90
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.31A 3cldA-5ufsA:
38.2		 3cldA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 9 LEU A  32
LEU A  35
MET A  73
ALA A  74
MET A 108
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.7A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
 0.74A 3cldA-5ufsA:
38.2		 3cldA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 9 LEU A  32
LEU A  35
MET A  73
MET A 108
GLN A 111
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.0A)
None
1TA  A 301 ( 2.8A)
 0.84A 3cldA-5ufsA:
38.2		 3cldA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 9 LEU A  32
LEU A  35
TRP A  69
MET A  73
ALA A  74
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.7A)
1TA  A 301 ( 2.8A)
 0.36A 3cldA-5ufsA:
38.2		 3cldA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 9 LEU A  32
LEU A  35
TRP A  69
MET A  73
GLN A 111
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
None
1TA  A 301 (-4.2A)
None
1TA  A 301 ( 2.8A)
 0.65A 3cldA-5ufsA:
38.2		 3cldA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
MET A  70
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.94A 3cldB-5ufsA:
38.3		 3cldB-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
MET A  70
ARG A  80
CYH A 112
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.45A 3cldB-5ufsA:
38.3		 3cldB-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 MET A  29
GLY A  36
GLN A  39
ARG A  80
MET A 108
CYH A 112
LEU A 201
 1TA  A 301 ( 2.9A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.8A)
 0.80A 3cldB-5ufsA:
38.3		 3cldB-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 8 LEU A  32
MET A  73
ALA A  74
LEU A  77
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.7A)
1TA  A 301 ( 3.4A)
1TA  A 301 ( 2.8A)
 0.40A 3cldB-5ufsA:
38.3		 3cldB-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 8 LEU A  32
MET A  73
LEU A  77
GLN A 111
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
None
1TA  A 301 ( 2.8A)
 0.53A 3cldB-5ufsA:
38.3		 3cldB-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
LEU A  35
GLN A  39
MET A  70
MET A  73
ARG A  80
MET A 115
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
 0.91A 3d90A-5ufsA:
36.5		 3d90A-5ufsA:
57.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ARG A  80
MET A 115
CYH A 205
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 0.60A 3d90A-5ufsA:
36.5		 3d90A-5ufsA:
57.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
CYH A 205
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 0.67A 3d90B-5ufsA:
36.4		 3d90B-5ufsA:
57.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
LEU A  32
LEU A  77
ARG A  80
MET A 108
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.19A 3erdA-5ufsA:
27.9		 3erdA-5ufsA:
29.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
LEU A  32
LEU A 201
LEU A  77
ARG A  80
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 1.17A 3erdA-5ufsA:
27.9		 3erdA-5ufsA:
29.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
GLY A  37
TRP A  69
MET A  70
CYH A 205
THR A 208
VAL A 216
 1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.3A)
 0.84A 3gn8A-5ufsA:
40.5		 3gn8A-5ufsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
MET A 115
CYH A 205
THR A 208
VAL A 216
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.3A)
 0.44A 3gn8A-5ufsA:
40.5		 3gn8A-5ufsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 TRP A  69
MET A  70
ARG A  80
GLN A 111
MET A 115
CYH A 205
 None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 1.37A 3gn8A-5ufsA:
40.5		 3gn8A-5ufsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLY A  37
GLN A  39
TRP A  69
MET A  70
CYH A 205
THR A 208
VAL A 216
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.3A)
1TA  A 301 (-4.0A)
 0.92A 3gn8B-5ufsA:
40.5		 3gn8B-5ufsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		12 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
MET A 115
CYH A 205
THR A 208
VAL A 216
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.3A)
1TA  A 301 (-4.0A)
 0.43A 3gn8B-5ufsA:
40.5		 3gn8B-5ufsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
VAL A  40
ARG A  80
MET A 115
LEU A 201
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 0.57A 3h52A-5ufsA:
26.8		 3h52A-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
GLY A  36
GLN A  39
VAL A  40
MET A  70
ARG A  80
MET A 115
LEU A 201
 1TA  A 301 (-3.5A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 0.58A 3h52A-5ufsA:
26.8		 3h52A-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 10 LEU A  32
TRP A  69
MET A  70
MET A  73
LEU A 201
 1TA  A 301 (-3.5A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.8A)
 0.85A 3h52B-5ufsA:
29.3		 3h52B-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 10 LEU A  35
MET A  70
MET A  73
MET A 221
LEU A 222
 1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
None
None
 1.41A 3h52B-5ufsA:
29.3		 3h52B-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 GLY A  36
GLN A  39
LEU A  77
ARG A  80
CYH A 112
MET A 115
ILE A 226
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
None
 1.32A 3h52B-5ufsA:
29.3		 3h52B-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 GLY A  36
GLY A  37
GLN A  39
VAL A  40
LEU A  77
ARG A  80
MET A 108
CYH A 112
MET A 115
CYH A 205
ILE A 225
 1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
None
 0.78A 3h52B-5ufsA:
29.3		 3h52B-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 GLY A  37
GLN A  39
VAL A  40
CYH A 205
ILE A 225
 None
1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.6A)
None
 1.09A 3h52B-5ufsA:
29.3		 3h52B-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 MET A  29
GLY A  36
GLY A  37
VAL A  40
ARG A  80
MET A 108
CYH A 112
ILE A 225
 1TA  A 301 ( 2.9A)
1TA  A 301 (-2.9A)
None
None
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 3.6A)
None
 0.90A 3h52B-5ufsA:
29.3		 3h52B-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 GLY A  36
GLN A  39
VAL A  40
TRP A  69
MET A  70
LEU A  77
ARG A  80
PHE A  92
MET A 115
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
 0.64A 3h52C-5ufsA:
27.3		 3h52C-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 GLY A  36
GLN A  39
VAL A  40
TRP A  69
MET A  70
LEU A  77
MET A 108
MET A 115
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
 1.06A 3h52C-5ufsA:
27.3		 3h52C-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 GLY A  37
GLN A  39
VAL A  40
TRP A  69
MET A  70
 None
1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
 0.96A 3h52C-5ufsA:
27.3		 3h52C-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
GLY A  36
GLN A  39
VAL A  40
TRP A  69
MET A  70
PHE A  92
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
 0.92A 3h52C-5ufsA:
27.3		 3h52C-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 GLY A  36
GLN A  39
VAL A  40
MET A  70
LEU A  77
ARG A  80
MET A 108
MET A 115
CYH A 205
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 0.89A 3h52D-5ufsA:
28.9		 3h52D-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 GLY A  36
GLN A  39
VAL A  40
MET A  70
LEU A  77
ARG A  80
MET A 108
MET A 115
LEU A 201
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 0.71A 3h52D-5ufsA:
28.9		 3h52D-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 GLY A  37
GLN A  39
VAL A  40
MET A  70
CYH A 205
 None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
 1.23A 3h52D-5ufsA:
28.9		 3h52D-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
VAL A  40
MET A  70
MET A 108
LEU A 201
 1TA  A 301 ( 2.9A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 3.8A)
 1.08A 3h52D-5ufsA:
28.9		 3h52D-5ufsA:
76.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 11 LEU A  32
LEU A  35
LEU A  77
ARG A  80
MET A 108
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 0.84A 3hm1B-5ufsA:
28.3		 3hm1B-5ufsA:
30.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 11 MET A  29
LEU A  35
LEU A  77
ARG A  80
MET A 108
 1TA  A 301 ( 2.9A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.20A 3hm1B-5ufsA:
28.3		 3hm1B-5ufsA:
30.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
MET A 115
LEU A 201
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.53A 3mneA-5ufsA:
37.4		 3mneA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 MET A  29
ASN A  33
GLY A  37
TRP A  69
MET A  70
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.90A 3mneA-5ufsA:
37.4		 3mneA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
GLY A  36
GLN A  39
MET A  70
ARG A  80
MET A 115
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.66A 3mnoA-5ufsA:
38.1		 3mnoA-5ufsA:
76.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
MET A  70
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.86A 3mnoA-5ufsA:
38.1		 3mnoA-5ufsA:
76.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 6 MET A  29
LEU A  32
TRP A  69
MET A  73
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
None
1TA  A 301 (-4.2A)
 0.14A 3mnoA-5ufsA:
38.1		 3mnoA-5ufsA:
76.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLY A  36
GLN A  39
MET A  70
ARG A  80
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.32A 3mnpA-5ufsA:
38.6		 3mnpA-5ufsA:
75.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
MET A  70
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.87A 3mnpA-5ufsA:
38.6		 3mnpA-5ufsA:
75.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 GLY A  36
GLN A  39
MET A  70
ARG A  80
MET A 115
LEU A 201
CYH A 205
THR A 208
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.72A 3mnpA-5ufsA:
38.6		 3mnpA-5ufsA:
75.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 6 MET A  29
LEU A  32
TRP A  69
MET A  73
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
None
1TA  A 301 (-4.2A)
 0.18A 3mnpA-5ufsA:
38.6		 3mnpA-5ufsA:
75.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 10 LEU A  32
LEU A  35
MET A  70
LEU A  77
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 0.45A 3ollA-5ufsA:
28.1		 3ollA-5ufsA:
31.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 10 MET A  29
LEU A  35
MET A  70
LEU A  77
ARG A  80
 1TA  A 301 ( 2.9A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 0.68A 3ollA-5ufsA:
28.1		 3ollA-5ufsA:
31.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  32
LEU A  35
MET A  70
LEU A  77
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 0.47A 3olsA-5ufsA:
29.2		 3olsA-5ufsA:
31.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 ASN A  33
GLN A  39
LEU A  77
ARG A  80
MET A 108
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.04A 3vhuA-5ufsA:
36.7		 3vhuA-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLN A  39
MET A  70
LEU A  77
ARG A  80
LEU A 201
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.38A 3vhuA-5ufsA:
36.7		 3vhuA-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
LEU A  90
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.16A 3vhuA-5ufsA:
36.7		 3vhuA-5ufsA:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
LEU A  35
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.87A 3zqtA-5ufsA:
35.5		 3zqtA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLN A  39
MET A  70
MET A  73
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.97A 3zqtA-5ufsA:
35.5		 3zqtA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
ARG A  80
MET A 108
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
 0.87A 4fn9A-5ufsA:
38.0		 4fn9A-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ALA A  74
ARG A  80
CYH A 205
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.7A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
 0.49A 4fn9A-5ufsA:
38.0		 4fn9A-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
ARG A  80
MET A 108
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-3.0A)
 1.02A 4fn9B-5ufsA:
38.0		 4fn9B-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
TRP A  69
MET A  70
ARG A  80
THR A 208
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
 0.48A 4fn9B-5ufsA:
38.0		 4fn9B-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
GLN A  39
TRP A  69
MET A  70
MET A  73
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
 1.36A 4hlwA-5ufsA:
35.2		 4hlwA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
MET A  73
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.83A 4hlwA-5ufsA:
35.2		 4hlwA-5ufsA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  32
LEU A  35
MET A  70
LEU A  77
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 0.51A 4j24A-5ufsA:
29.2		 4j24A-5ufsA:
31.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
ARG A  80
MET A 108
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 0.88A 4ltwA-5ufsA:
38.4		 4ltwA-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
ASN A  33
LEU A  35
GLN A  39
MET A  70
ARG A  80
LEU A 201
CYH A 205
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
 0.46A 4ltwA-5ufsA:
38.4		 4ltwA-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 8 TRP A  69
ALA A  74
MET A 115
PHE A 204
THR A 208
VAL A 216
PHE A 218
 None
1TA  A 301 ( 3.7A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.7A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.3A)
1TA  A 301 (-4.0A)
 0.62A 4ltwA-5ufsA:
38.4		 4ltwA-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 8 TRP A  69
MET A  73
ALA A  74
MET A 115
THR A 208
VAL A 216
PHE A 218
 None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.7A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.3A)
1TA  A 301 (-4.0A)
 0.68A 4ltwA-5ufsA:
38.4		 4ltwA-5ufsA:
73.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
 0.58A 4ojbA-5ufsA:
34.5		 4ojbA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  73
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.88A 4ojbA-5ufsA:
34.5		 4ojbA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		4 / 7 ASN A  33
LEU A 201
ILE A 225
ILE A 226
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.8A)
None
None
 0.59A 4ojbA-5ufsA:
34.5		 4ojbA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 GLY A  37
GLN A  39
MET A  70
ARG A  80
ILE A 226
 None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
None
 1.04A 4ok1A-5ufsA:
35.0		 4ok1A-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 LEU A  32
LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
ILE A 226
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
None
 0.76A 4ok1A-5ufsA:
35.0		 4ok1A-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
ILE A 226
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
None
 0.79A 4okbA-5ufsA:
34.3		 4okbA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  73
ARG A  80
ILE A 226
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
None
 0.95A 4okbA-5ufsA:
34.3		 4okbA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 GLY A  37
GLN A  39
MET A  70
ARG A  80
ILE A 226
 None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
None
 1.04A 4oktA-5ufsA:
34.7		 4oktA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 LEU A  32
LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
MET A 115
ILE A 226
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
None
 0.85A 4oktA-5ufsA:
34.7		 4oktA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
ILE A 226
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
None
 0.66A 4okwA-5ufsA:
34.4		 4okwA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  73
ARG A  80
ILE A 226
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
None
 0.84A 4okwA-5ufsA:
34.4		 4okwA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
 0.58A 4okxA-5ufsA:
34.5		 4okxA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  73
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.87A 4okxA-5ufsA:
34.5		 4okxA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
LEU A  35
GLY A  36
GLN A  39
MET A  70
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
 0.71A 4olmA-5ufsA:
34.0		 4olmA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
GLY A  36
GLN A  39
MET A  73
ARG A  80
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
 0.87A 4olmA-5ufsA:
34.0		 4olmA-5ufsA:
54.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  36
LEU A  96
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.43A 4p6xA-5ufsA:
38.2		 4p6xA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  37
MET A  70
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.95A 4p6xA-5ufsA:
38.2		 4p6xA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 GLN A  39
MET A  70
LEU A  77
ARG A  80
GLN A 111
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
None
 1.19A 4p6xA-5ufsA:
38.2		 4p6xA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
MET A  70
LEU A  77
ARG A  80
THR A 208
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.35A 4p6xA-5ufsA:
38.2		 4p6xA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 MET A  29
LEU A  32
ASN A  33
GLY A  36
GLN A  39
MET A  70
ARG A  80
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.49A 4p6xA-5ufsA:
38.2		 4p6xA-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 11 MET A  29
ASN A  33
LEU A  35
GLN A  39
TRP A  69
MET A  70
MET A  73
ARG A  80
THR A 208
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
 0.33A 4p6xC-5ufsA:
38.9		 4p6xC-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 11 TRP A  69
MET A  70
MET A  73
ARG A  80
GLN A 111
 None
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
None
 1.04A 4p6xC-5ufsA:
38.9		 4p6xC-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  36
LEU A  96
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.42A 4p6xE-5ufsA:
38.3		 4p6xE-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  37
MET A  70
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.95A 4p6xE-5ufsA:
38.3		 4p6xE-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
MET A  70
MET A  73
LEU A  77
ARG A  80
THR A 208
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.27A 4p6xE-5ufsA:
38.3		 4p6xE-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  70
MET A  73
LEU A  77
ARG A  80
GLN A 111
 1TA  A 301 ( 3.1A)
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
None
 1.11A 4p6xE-5ufsA:
38.3		 4p6xE-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
LEU A  77
ARG A  80
MET A 115
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.44A 4p6xG-5ufsA:
38.8		 4p6xG-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  36
LEU A  96
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.42A 4p6xG-5ufsA:
38.8		 4p6xG-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
TRP A  69
MET A  70
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.89A 4p6xG-5ufsA:
38.8		 4p6xG-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 GLN A  39
TRP A  69
MET A  70
LEU A  77
ARG A  80
GLN A 111
MET A 115
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 2.8A)
 1.05A 4p6xG-5ufsA:
38.8		 4p6xG-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLY A  36
LEU A  96
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.44A 4p6xI-5ufsA:
38.7		 4p6xI-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
GLN A  39
MET A  70
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.12A 4p6xI-5ufsA:
38.7		 4p6xI-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 GLN A  39
MET A  70
LEU A  77
ARG A  80
GLN A 111
MET A 115
 1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 2.8A)
 1.17A 4p6xI-5ufsA:
38.7		 4p6xI-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 LEU A  32
ASN A  33
GLY A  36
GLN A  39
MET A  70
LEU A  77
ARG A  80
MET A 115
THR A 208
PHE A 218
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.45A 4p6xI-5ufsA:
38.7		 4p6xI-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
MET A 115
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.47A 4p6xK-5ufsA:
38.8		 4p6xK-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
TRP A  69
MET A  70
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.90A 4p6xK-5ufsA:
38.8		 4p6xK-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 GLN A  39
TRP A  69
MET A  70
ARG A  80
GLN A 111
MET A 115
 1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 2.8A)
 1.17A 4p6xK-5ufsA:
38.8		 4p6xK-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.33A 4p6xK-5ufsA:
38.8		 4p6xK-5ufsA:
76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 ASN A  33
GLN A  39
ARG A  80
MET A 108
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 (-4.0A)
 0.89A 4udaA-5ufsA:
37.3		 4udaA-5ufsA:
62.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		8 / 12 ASN A  33
GLN A  39
MET A  70
ARG A  80
MET A 115
LEU A 201
CYH A 205
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
1TA  A 301 (-4.0A)
 0.36A 4udaA-5ufsA:
37.3		 4udaA-5ufsA:
62.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
TRP A  69
MET A  70
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.92A 4udcA-5ufsA:
38.9		 4udcA-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 MET A  29
LEU A  32
ASN A  33
GLY A  36
GLN A  39
TRP A  69
MET A  70
ARG A  80
MET A 115
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.51A 4udcA-5ufsA:
38.9		 4udcA-5ufsA:
71.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  35
TRP A  69
LEU A  77
ARG A  80
MET A 108
 1TA  A 301 ( 3.6A)
None
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 0.67A 4xi3C-5ufsA:
24.8		 4xi3C-5ufsA:
30.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
LEU A  32
LEU A  77
ARG A  80
MET A 108
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 1.21A 4zn7A-5ufsA:
28.1		 4zn7A-5ufsA:
30.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
LEU A  35
LEU A  77
ARG A  80
MET A 108
 1TA  A 301 ( 2.9A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
 0.85A 5gs4A-5ufsA:
27.0		 5gs4A-5ufsA:
30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSG_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.36A 5ksgB-5ufsA:
1.1		 5ksgB-5ufsA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSN_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.36A 5ksnA-5ufsA:
0.6		 5ksnA-5ufsA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSN_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.36A 5ksnB-5ufsA:
0.7		 5ksnB-5ufsA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KT8_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.35A 5kt8B-5ufsA:
0.3		 5kt8B-5ufsA:
16.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 LEU A  32
ASN A  33
TRP A  69
MET A  70
LEU A  77
LEU A 201
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 ( 3.8A)
 0.42A 5mwyA-5ufsA:
36.9		 5mwyA-5ufsA:
53.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 TRP A  69
MET A  70
LEU A  77
MET A 115
LEU A 201
 None
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 1.01A 5mwyA-5ufsA:
36.9		 5mwyA-5ufsA:
53.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 6 GLN A  39
ARG A  80
PHE A  92
CYH A 205
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 (-3.6A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.32A 5mwyA-5ufsA:
36.9		 5mwyA-5ufsA:
53.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 ASN A  33
GLY A  37
GLN A  39
MET A  70
THR A 208
PHE A 218
 1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 1.12A 5nfpA-5ufsA:
38.9		 5nfpA-5ufsA:
71.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 GLY A  36
GLN A  39
ARG A  80
GLN A 111
CYH A 112
MET A 115
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
 1.35A 5nfpA-5ufsA:
38.9		 5nfpA-5ufsA:
71.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 GLY A  36
GLN A  39
MET A  70
ARG A  80
MET A 108
CYH A 112
MET A 115
 1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
 0.83A 5nfpA-5ufsA:
38.9		 5nfpA-5ufsA:
71.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 MET A  29
ASN A  33
GLY A  36
GLN A  39
MET A  70
ARG A  80
CYH A 112
MET A 115
THR A 208
PHE A 218
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.1A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.0A)
 0.45A 5nfpA-5ufsA:
38.9		 5nfpA-5ufsA:
71.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXS_B_NIZB806_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.35A 5sxsB-5ufsA:
0.2		 5sxsB-5ufsA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYI_B_NIZB805_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.35A 5syiB-5ufsA:
0.4		 5syiB-5ufsA:
16.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 LEU A  32
LEU A  35
MET A  70
LEU A  77
ARG A  80
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 0.47A 5toaA-5ufsA:
26.4		 5toaA-5ufsA:
30.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 12 MET A  29
LEU A  35
MET A  70
LEU A  77
ARG A  80
 1TA  A 301 ( 2.9A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 3.1A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
 0.71A 5toaB-5ufsA:
26.4		 5toaB-5ufsA:
30.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 LEU A  32
LEU A  35
GLY A  36
GLY A  37
GLN A  39
VAL A  40
MET A  73
LEU A  77
ARG A  80
CYH A 112
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
 0.67A 5uc1A-5ufsA:
25.7		 5uc1A-5ufsA:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		11 / 12 LEU A  35
GLY A  36
GLY A  37
GLN A  39
VAL A  40
TRP A  69
MET A  73
LEU A  77
ARG A  80
CYH A 112
MET A 115
 1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
None
None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
 0.85A 5uc1A-5ufsA:
25.7		 5uc1A-5ufsA:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		12 / 12 LEU A  32
ASN A  33
LEU A  35
GLY A  36
GLY A  37
GLN A  39
VAL A  40
MET A  73
LEU A  77
ARG A  80
CYH A 112
MET A 115
 1TA  A 301 (-3.5A)
1TA  A 301 (-3.0A)
1TA  A 301 ( 3.6A)
1TA  A 301 (-2.9A)
None
1TA  A 301 (-3.0A)
None
1TA  A 301 (-4.2A)
1TA  A 301 ( 3.4A)
1TA  A 301 (-3.5A)
1TA  A 301 ( 3.6A)
1TA  A 301 ( 2.8A)
 0.71A 5uc1B-5ufsA:
25.8		 5uc1B-5ufsA:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		9 / 12 ASN A  33
GLY A  36
GLN A  39
MET A  73
ARG A  80
PHE A  92
MET A 108
MET A 115
LEU A 201
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-4.2A)
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
 0.62A 5uc3A-5ufsA:
33.2		 5uc3A-5ufsA:
75.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 ASN A  33
GLY A  36
GLN A  39
TRP A  69
ARG A  80
PHE A  92
MET A 108
MET A 115
LEU A 201
CYH A 205
 1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 3.0A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
 0.72A 5uc3A-5ufsA:
33.2		 5uc3A-5ufsA:
75.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		7 / 12 MET A  29
ASN A  33
GLY A  36
TRP A  69
MET A 108
LEU A 201
CYH A 205
 1TA  A 301 ( 2.9A)
1TA  A 301 (-3.0A)
1TA  A 301 (-2.9A)
None
1TA  A 301 ( 3.0A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
 1.11A 5uc3A-5ufsA:
33.2		 5uc3A-5ufsA:
75.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		10 / 12 LEU A  32
GLY A  36
GLN A  39
VAL A  40
TRP A  69
ARG A  80
PHE A  92
MET A 115
LEU A 201
CYH A 205
 1TA  A 301 (-3.5A)
1TA  A 301 (-2.9A)
1TA  A 301 (-3.0A)
None
None
1TA  A 301 (-3.5A)
1TA  A 301 (-4.4A)
1TA  A 301 ( 2.8A)
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
 0.53A 5uc3B-5ufsA:
33.0		 5uc3B-5ufsA:
75.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 MET A  29
GLY A  36
VAL A  40
TRP A  69
LEU A 201
CYH A 205
 1TA  A 301 ( 2.9A)
1TA  A 301 (-2.9A)
None
None
1TA  A 301 ( 3.8A)
1TA  A 301 (-3.6A)
 0.97A 5uc3B-5ufsA:
33.0		 5uc3B-5ufsA:
75.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		6 / 12 VAL A  40
TRP A  69
ARG A  80
GLN A 111
MET A 115
CYH A 205
 None
None
1TA  A 301 (-3.5A)
None
1TA  A 301 ( 2.8A)
1TA  A 301 (-3.6A)
 1.46A 5uc3B-5ufsA:
33.0		 5uc3B-5ufsA:
75.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDQ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.40A 6cdqA-5ufsA:
undetectable		 6cdqA-5ufsA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.38A 6cdqB-5ufsA:
0.6		 6cdqB-5ufsA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CFQ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5ufs ANCESTRAL
GLUCOCORTICOID
RECEPTOR2
(unidentified) 		5 / 9 ARG A  80
VAL A  12
GLY A  78
SER A  81
LEU A  77
 1TA  A 301 (-3.5A)
None
None
None
1TA  A 301 ( 3.4A)
 1.36A 6cfqB-5ufsA:
0.3		 6cfqB-5ufsA:
17.27