SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1SY'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4ksy STIMULATOR OF
INTERFERON GENES
PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 299
TYR A 163
TYR A 167
LEU A 172
 None
None
1SY  A 500 (-3.9A)
None
 1.06A 3v81A-4ksyA:
undetectable		 3v81A-4ksyA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 4ksy STIMULATOR OF
INTERFERON GENES
PROTEIN
(Homo
sapiens) 		4 / 6 TYR A 240
LEU A 172
GLU A 260
LEU A 198
 1SY  A 500 (-4.7A)
None
1SY  A 500 (-4.2A)
None
 1.32A 5xooA-4ksyA:
undetectable		 5xooA-4ksyA:
13.15