SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1PS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2rfq 3-HSA HYDROXYLASE,
OXYGENASE
(Rhodococcus
jostii) 		4 / 8 PHE A 338
SER A 341
ALA A 347
LEU A 346
 None
1PS  A 392 ( 4.1A)
1PS  A 392 ( 3.8A)
None
 1.01A 2o01A-2rfqA:
undetectable		 2o01A-2rfqA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6g0c UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA
(Legionella
pneumophila) 		5 / 12 ILE A 326
ALA A 329
ASN A 404
VAL A 293
ILE A 315
 None
None
1PS  A1001 (-2.9A)
None
None
 1.07A 3e00A-6g0cA:
2.7		 3e00A-6g0cA:
10.96