SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1N1'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3oht P38A
(Salmo
salar) 		4 / 7 ASP A 151
ASP A 169
TYR A 324
ARG A  74
 None
1N1  A1000 (-3.4A)
None
None
 1.31A 1ceaB-3ohtA:
undetectable		 1ceaB-3ohtA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 3oht P38A
(Salmo
salar) 		4 / 7 ASP A 151
ASP A 169
TYR A 324
ARG A  74
 None
1N1  A1000 (-3.4A)
None
None
 1.32A 1cebB-3ohtA:
undetectable		 1cebB-3ohtA:
13.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
MET B 309
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.81A 1iepA-4xeyB:
35.1		 1iepA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.67A 1iepA-4xeyB:
35.1		 1iepA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.85A 1iepA-4xeyB:
35.1		 1iepA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 VAL B 308
VAL B 318
ILE B 332
MET B 337
 None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.55A 1iepA-4xeyB:
35.1		 1iepA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.5A)
 0.95A 1iepB-4xeyB:
29.0		 1iepB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.5A)
 0.85A 1iepB-4xeyB:
29.0		 1iepB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 7 LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.53A 1iepB-4xeyB:
29.0		 1iepB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 7 VAL B 308
ILE B 332
MET B 337
LEU B 389
 None
1N1  B 601 (-4.1A)
None
1N1  B 601 (-4.3A)
 0.62A 1iepB-4xeyB:
29.0		 1iepB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 7 VAL B 308
VAL B 318
ILE B 332
LEU B 389
 None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-4.3A)
 0.66A 1iepB-4xeyB:
29.0		 1iepB-4xeyB:
71.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 8 LEU B 346
VAL B 390
CYH B 388
GLY B 340
 None
None
None
1N1  B 601 (-3.5A)
 1.02A 1jlfA-4xeyB:
undetectable
1jlfB-4xeyB:
undetectable		 1jlfA-4xeyB:
20.51
1jlfB-4xeyB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M17_A_AQ4A999_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3oht P38A
(Salmo
salar) 		7 / 12 ALA A  52
LYS A  54
GLU A  72
LEU A 105
THR A 107
LEU A 109
MET A 110
 1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.2A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
None
 0.57A 1m17A-3ohtA:
3.8		 1m17A-3ohtA:
27.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M17_A_AQ4A999_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 LEU B 267
ALA B 288
LYS B 290
THR B 334
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.42A 1m17A-4xeyB:
28.0		 1m17A-4xeyB:
28.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 LEU B 267
VAL B 275
ILE B 312
VAL B 318
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.88A 1opjA-4xeyB:
34.0		 1opjA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.80A 1opjA-4xeyB:
34.0		 1opjA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
VAL B 318
THR B 334
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.64A 1opjA-4xeyB:
34.0		 1opjA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
THR B 334
PHE B 336
GLY B 340
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.5A)
 0.87A 1opjB-4xeyB:
27.9		 1opjB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
LYS B 290
VAL B 308
ILE B 332
 1N1  B 601 (-3.7A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-4.1A)
 0.91A 1opjB-4xeyB:
27.9		 1opjB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
VAL B 308
ILE B 332
MET B 337
 1N1  B 601 (-3.7A)
None
1N1  B 601 (-4.1A)
None
 0.64A 1opjB-4xeyB:
27.9		 1opjB-4xeyB:
71.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_1
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
VAL B 318
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.78A 1t46A-4xeyB:
26.6		 1t46A-4xeyB:
29.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 9 LEU B 267
VAL B 275
ALA B 288
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.31A 1xbbA-4xeyB:
29.5		 1xbbA-4xeyB:
33.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 ALA B 288
THR B 334
GLY B 340
LEU B 343
ASP B 344
LEU B 389
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
None
1N1  B 601 (-4.3A)
 0.87A 1xkkA-4xeyB:
26.3		 1xkkA-4xeyB:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 THR B 334
GLY B 340
LEU B 343
ASP B 344
ARG B 347
LEU B 389
 1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
None
None
1N1  B 601 (-4.3A)
 0.68A 1xkkA-4xeyB:
26.3		 1xkkA-4xeyB:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3oht P38A
(Salmo
salar) 		5 / 9 LYS A  54
LEU A  87
LEU A 105
LEU A 109
MET A 110
 1N1  A1000 (-4.5A)
None
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
None
 0.77A 1xkkA-3ohtA:
6.8		 1xkkA-3ohtA:
27.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3oht P38A
(Salmo
salar) 		5 / 9 VAL A  39
LEU A  87
LEU A 105
LEU A 109
MET A 110
 1N1  A1000 (-4.6A)
None
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
None
 0.77A 1xkkA-3ohtA:
6.8		 1xkkA-3ohtA:
27.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 ALA B 288
LYS B 290
MET B 309
VAL B 318
ILE B 332
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.65A 2gqgA-4xeyB:
32.2		 2gqgA-4xeyB:
71.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.52A 2gqgA-4xeyB:
32.2		 2gqgA-4xeyB:
71.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.40A 2gqgB-4xeyB:
38.3		 2gqgB-4xeyB:
71.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.89A 2hyyA-4xeyB:
35.3		 2hyyA-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.78A 2hyyB-4xeyB:
35.8		 2hyyB-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
LYS B 290
VAL B 318
ILE B 332
 1N1  B 601 (-3.7A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.91A 2hyyB-4xeyB:
35.8		 2hyyB-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
VAL B 308
ILE B 332
MET B 337
 1N1  B 601 (-3.7A)
None
1N1  B 601 (-4.1A)
None
 0.68A 2hyyB-4xeyB:
35.8		 2hyyB-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.59A 2hyyB-4xeyB:
35.8		 2hyyB-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
ILE B 312
VAL B 318
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.69A 2hyyC-4xeyB:
36.1		 2hyyC-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 6 LEU B 267
LYS B 290
VAL B 308
MET B 309
ILE B 332
 1N1  B 601 (-3.7A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-3.7A)
1N1  B 601 (-4.1A)
 0.88A 2hyyC-4xeyB:
36.1		 2hyyC-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 6 LEU B 267
VAL B 308
MET B 309
ILE B 332
MET B 337
 1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.7A)
1N1  B 601 (-4.1A)
None
 0.61A 2hyyC-4xeyB:
36.1		 2hyyC-4xeyB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
ILE B 332
THR B 334
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.83A 2hyyD-4xeyB:
35.4		 2hyyD-4xeyB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITO_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
ALA B 288
LYS B 290
MET B 309
THR B 334
GLY B 340
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
 0.67A 2itoA-4xeyB:
26.8		 2itoA-4xeyB:
28.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITO_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 LEU B 267
ALA B 288
LYS B 290
THR B 334
GLY B 340
ASP B 344
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.63A 2itoA-4xeyB:
26.8		 2itoA-4xeyB:
28.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 309
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.69A 2ityA-4xeyB:
26.7		 2ityA-4xeyB:
28.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 309
THR B 334
GLY B 340
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
 0.61A 2itzA-4xeyB:
26.3		 2itzA-4xeyB:
28.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
THR B 334
GLY B 340
ASP B 344
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.68A 2itzA-4xeyB:
26.3		 2itzA-4xeyB:
28.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3oht P38A
(Salmo
salar) 		3 / 3 LEU A 105
LEU A 109
MET A 110
 1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
None
 0.43A 2itzA-3ohtA:
16.6		 2itzA-3ohtA:
26.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 332
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.59A 2oiqA-4xeyB:
32.6		 2oiqA-4xeyB:
36.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.83A 2pl0A-4xeyB:
26.1		 2pl0A-4xeyB:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 VAL B 275
ALA B 288
LYS B 290
MET B 309
VAL B 318
ILE B 332
THR B 334
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
 0.76A 2pl0A-4xeyB:
26.1		 2pl0A-4xeyB:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 VAL B 275
ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
 0.83A 2pl0A-4xeyB:
26.1		 2pl0A-4xeyB:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
ALA B 288
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.41A 2xp2A-4xeyB:
13.4		 2xp2A-4xeyB:
31.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
LYS B 290
MET B 309
ILE B 332
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.61A 2y6oA-4xeyB:
28.0		 2y6oA-4xeyB:
31.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_C_B49C1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 VAL B 275
ALA B 288
MET B 337
GLY B 340
ASP B 344
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.52A 2y7jC-4xeyB:
19.8		 2y7jC-4xeyB:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_D_B49D1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 VAL B 275
ALA B 288
MET B 337
GLY B 340
ASP B 344
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.66A 2y7jD-4xeyB:
25.8		 2y7jD-4xeyB:
26.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZVA_A_1N1A513_1
(TYROSINE-PROTEIN
KINASE LYN)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		11 / 12 LEU B 267
ALA B 288
LYS B 290
MET B 309
VAL B 318
ILE B 332
THR B 334
MET B 337
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.58A 2zvaA-4xeyB:
33.3		 2zvaA-4xeyB:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOX_A_EMHA901_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 10 LEU B 267
ALA B 288
LYS B 290
VAL B 318
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.59A 3aoxA-4xeyB:
25.2		 3aoxA-4xeyB:
32.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BBT_B_FMMB91_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 VAL B 275
ALA B 288
LEU B 320
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.63A 3bbtB-4xeyB:
25.0		 3bbtB-4xeyB:
29.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C7Q_A_XINA1172_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
GLU B 277
ALA B 288
LYS B 290
VAL B 318
PHE B 336
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.83A 3c7qA-4xeyB:
30.8		 3c7qA-4xeyB:
32.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 LEU B 267
VAL B 275
LYS B 290
LYS B 304
ILE B 332
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-4.1A)
None
 1.16A 3cs9A-4xeyB:
35.8		 3cs9A-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 LEU B 267
VAL B 275
LYS B 290
VAL B 318
ILE B 332
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.83A 3cs9A-4xeyB:
35.8		 3cs9A-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 LEU B 267
VAL B 275
LYS B 304
ILE B 332
PHE B 336
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
None
1N1  B 601 (-4.1A)
1N1  B 601 ( 4.2A)
None
 0.98A 3cs9A-4xeyB:
35.8		 3cs9A-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 LEU B 267
VAL B 275
VAL B 318
ILE B 332
PHE B 336
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 ( 4.2A)
None
 0.68A 3cs9A-4xeyB:
35.8		 3cs9A-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 ALA B 288
VAL B 308
MET B 309
LEU B 317
THR B 334
GLY B 340
HIS B 380
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.52A 3cs9A-4xeyB:
35.8		 3cs9A-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 308
MET B 309
ILE B 312
LEU B 317
GLY B 340
HIS B 380
LEU B 389
ALA B 399
 None
1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.66A 3cs9A-4xeyB:
35.8		 3cs9A-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 ALA B 288
VAL B 308
MET B 309
ILE B 312
LEU B 317
GLY B 340
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
 0.68A 3cs9B-4xeyB:
30.5		 3cs9B-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 ALA B 288
VAL B 308
MET B 309
LEU B 317
THR B 334
GLY B 340
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
 0.49A 3cs9B-4xeyB:
30.5		 3cs9B-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 9 LEU B 267
VAL B 275
LYS B 290
VAL B 318
ILE B 332
PHE B 378
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
None
 0.81A 3cs9B-4xeyB:
30.5		 3cs9B-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 9 LEU B 267
VAL B 275
VAL B 318
ILE B 332
PHE B 378
LEU B 389
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
1N1  B 601 (-4.3A)
None
 0.67A 3cs9B-4xeyB:
30.5		 3cs9B-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 ALA B 288
VAL B 308
MET B 309
ILE B 312
LEU B 317
THR B 334
PHE B 336
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
 0.72A 3cs9C-4xeyB:
29.2		 3cs9C-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 VAL B 308
MET B 309
ILE B 312
LEU B 317
THR B 334
PHE B 378
 None
1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-3.3A)
None
 1.48A 3cs9C-4xeyB:
29.2		 3cs9C-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
LYS B 290
VAL B 318
ILE B 332
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.83A 3cs9C-4xeyB:
29.2		 3cs9C-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
VAL B 318
ILE B 332
MET B 337
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
None
 0.67A 3cs9C-4xeyB:
29.2		 3cs9C-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 ALA B 288
VAL B 308
MET B 309
ILE B 312
LEU B 317
PHE B 336
GLY B 340
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
None
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
 0.68A 3cs9D-4xeyB:
33.6		 3cs9D-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 ALA B 288
VAL B 308
MET B 309
LEU B 317
THR B 334
PHE B 336
GLY B 340
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
 0.52A 3cs9D-4xeyB:
33.6		 3cs9D-4xeyB:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0F_B_B49B9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 LEU B 267
VAL B 275
ALA B 288
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.71A 3g0fB-4xeyB:
30.6		 3g0fB-4xeyB:
30.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.41A 3g5dA-4xeyB:
27.3		 3g5dA-4xeyB:
36.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_B_1N1B1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.51A 3g5dB-4xeyB:
27.4		 3g5dB-4xeyB:
36.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		5 / 12 ALA A  52
GLU A  72
LEU A  76
THR A 107
LEU A 168
 1N1  A1000 (-3.7A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
1N1  A1000 (-3.3A)
1N1  A1000 ( 3.7A)
 0.96A 3gcsA-3ohtA:
16.4		 3gcsA-3ohtA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		7 / 12 ALA A  52
LEU A  75
LEU A  76
ILE A  85
THR A 107
ILE A 142
LEU A 168
 1N1  A1000 (-3.7A)
None
1N1  A1000 (-4.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
None
1N1  A1000 ( 3.7A)
 0.74A 3gcsA-3ohtA:
16.4		 3gcsA-3ohtA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		7 / 12 VAL A  39
ALA A  52
LEU A  75
LEU A  76
ILE A  85
THR A 107
ILE A 142
 1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
None
1N1  A1000 (-4.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
None
 0.72A 3gcsA-3ohtA:
16.4		 3gcsA-3ohtA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		5 / 6 MET A  79
VAL A  84
LEU A 109
MET A 110
ILE A 147
 None
None
1N1  A1000 (-4.7A)
None
None
 1.07A 3gcsA-3ohtA:
16.5		 3gcsA-3ohtA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3oht P38A
(Salmo
salar) 		8 / 12 VAL A  39
ALA A  52
GLU A  72
ILE A  85
THR A 107
ALA A 158
LEU A 168
PHE A 170
 1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.2A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
None
1N1  A1000 ( 3.7A)
1N1  A1000 (-4.5A)
 1.01A 3gp0A-3ohtA:
18.9		 3gp0A-3ohtA:
68.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3oht P38A
(Salmo
salar) 		7 / 12 VAL A  39
ALA A  52
GLU A  72
LEU A  75
LEU A  76
THR A 107
LEU A 168
 1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.2A)
None
1N1  A1000 (-4.7A)
1N1  A1000 (-3.3A)
1N1  A1000 ( 3.7A)
 0.64A 3gp0A-3ohtA:
18.9		 3gp0A-3ohtA:
68.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3oht P38A
(Salmo
salar) 		8 / 12 VAL A  39
ALA A  52
GLU A  72
LEU A  76
ILE A  85
THR A 107
ALA A 158
LEU A 168
 1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
None
1N1  A1000 ( 3.7A)
 0.69A 3gp0A-3ohtA:
18.9		 3gp0A-3ohtA:
68.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3oht P38A
(Salmo
salar) 		6 / 7 LYS A  54
VAL A  84
LEU A 105
LEU A 109
MET A 110
ILE A 167
 1N1  A1000 (-4.5A)
None
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
None
None
 0.82A 3gp0A-3ohtA:
18.9		 3gp0A-3ohtA:
68.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.78A 3gvuA-4xeyB:
29.1		 3gvuA-4xeyB:
64.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		5 / 12 ALA A  52
ILE A  85
THR A 107
LEU A 109
PHE A 170
 1N1  A1000 (-3.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
1N1  A1000 (-4.5A)
 0.71A 3hecA-3ohtA:
35.2		 3hecA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		5 / 12 ALA A  52
ILE A  85
THR A 107
LEU A 168
PHE A 170
 1N1  A1000 (-3.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
1N1  A1000 ( 3.7A)
1N1  A1000 (-4.5A)
 0.85A 3hecA-3ohtA:
35.2		 3hecA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		9 / 12 VAL A  31
ALA A  52
LYS A  54
GLU A  72
LEU A  75
LEU A  76
ILE A  85
THR A 107
LEU A 168
 1N1  A1000 ( 4.3A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
None
1N1  A1000 (-4.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
1N1  A1000 ( 3.7A)
 0.63A 3hecA-3ohtA:
35.2		 3hecA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		8 / 12 VAL A  31
ALA A  52
LYS A  54
GLU A  72
LEU A  76
ILE A  85
THR A 107
LEU A 109
 1N1  A1000 ( 4.3A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
 0.64A 3hecA-3ohtA:
35.2		 3hecA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		6 / 12 VAL A  31
VAL A  39
ALA A  52
LEU A 152
ILE A  85
THR A 107
 1N1  A1000 ( 4.3A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
None
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
 1.48A 3hegA-3ohtA:
18.6		 3hegA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		8 / 12 VAL A  31
VAL A  39
ALA A  52
LYS A  54
GLU A  72
LEU A  75
LEU A  76
THR A 107
 1N1  A1000 ( 4.3A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
None
1N1  A1000 (-4.7A)
1N1  A1000 (-3.3A)
 0.77A 3hegA-3ohtA:
18.6		 3hegA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		9 / 12 VAL A  31
VAL A  39
ALA A  52
LYS A  54
LEU A  75
LEU A  76
ILE A  85
THR A 107
ILE A 142
 1N1  A1000 ( 4.3A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
None
1N1  A1000 (-4.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
None
 0.68A 3hegA-3ohtA:
18.6		 3hegA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		7 / 12 VAL A  31
VAL A  39
ALA A  52
LYS A  54
LEU A  76
THR A 107
ILE A 147
 1N1  A1000 ( 4.3A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.7A)
1N1  A1000 (-3.3A)
None
 1.33A 3hegA-3ohtA:
18.6		 3hegA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		6 / 12 VAL A  39
LYS A  54
GLU A  72
LEU A  76
THR A 107
ASP A 151
 1N1  A1000 (-4.6A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
1N1  A1000 (-3.3A)
None
 1.44A 3hegA-3ohtA:
18.6		 3hegA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		5 / 6 MET A  79
VAL A  84
ILE A 147
ILE A 167
LEU A 168
 None
None
None
None
1N1  A1000 ( 3.7A)
 0.67A 3hegA-3ohtA:
18.6		 3hegA-3ohtA:
87.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
MET B 309
ILE B 312
LEU B 317
HIS B 380
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
None
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.63A 3ik3A-4xeyB:
36.3		 3ik3A-4xeyB:
92.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 7 LEU B 267
VAL B 308
ILE B 332
MET B 337
 1N1  B 601 (-3.7A)
None
1N1  B 601 (-4.1A)
None
 0.60A 3ik3A-4xeyB:
36.3		 3ik3A-4xeyB:
92.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
MET B 309
ILE B 312
LEU B 317
HIS B 380
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
None
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.59A 3ik3B-4xeyB:
30.1		 3ik3B-4xeyB:
92.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 7 LEU B 267
VAL B 308
ILE B 332
MET B 337
 1N1  B 601 (-3.7A)
None
1N1  B 601 (-4.1A)
None
 0.63A 3ik3B-4xeyB:
30.1		 3ik3B-4xeyB:
92.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
ALA B 288
LYS B 290
MET B 309
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.55A 3k54A-4xeyB:
26.7		 3k54A-4xeyB:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.79A 3k5vA-4xeyB:
34.2		 3k5vA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
LYS B 290
VAL B 318
ILE B 332
 1N1  B 601 (-3.7A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.82A 3k5vA-4xeyB:
34.2		 3k5vA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.77A 3k5vB-4xeyB:
34.2		 3k5vB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
LYS B 290
VAL B 318
ILE B 332
 1N1  B 601 (-3.7A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.91A 3k5vB-4xeyB:
34.2		 3k5vB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3oht P38A
(Salmo
salar) 		8 / 8 VAL A  31
ALA A  52
LYS A  54
GLU A  72
LEU A 105
THR A 107
LEU A 109
MET A 110
 1N1  A1000 ( 4.3A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.2A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
None
 0.47A 3lfaA-3ohtA:
15.7		 3lfaA-3ohtA:
84.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 11 ALA B 288
LYS B 290
VAL B 318
PHE B 336
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.79A 3miyA-4xeyB:
26.2		 3miyA-4xeyB:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_B_B49B2_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 ALA B 288
LYS B 290
PHE B 336
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.59A 3miyB-4xeyB:
27.2		 3miyB-4xeyB:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.86A 3ms9A-4xeyB:
35.1		 3ms9A-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.73A 3ms9A-4xeyB:
35.1		 3ms9A-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 VAL B 308
VAL B 318
ILE B 332
MET B 337
 None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.51A 3ms9A-4xeyB:
35.1		 3ms9A-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.86A 3ms9B-4xeyB:
35.4		 3ms9B-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.86A 3mssA-4xeyB:
35.4		 3mssA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.74A 3mssA-4xeyB:
35.4		 3mssA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 VAL B 308
VAL B 318
ILE B 332
MET B 337
 None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.54A 3mssA-4xeyB:
35.4		 3mssA-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
MET B 309
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.46A 3mssB-4xeyB:
29.7		 3mssB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 VAL B 275
ALA B 288
MET B 309
THR B 334
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.66A 3mssB-4xeyB:
29.7		 3mssB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 7 LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.82A 3mssB-4xeyB:
29.7		 3mssB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 7 VAL B 308
VAL B 318
ILE B 332
MET B 337
 None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.55A 3mssB-4xeyB:
29.7		 3mssB-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.87A 3mssC-4xeyB:
35.3		 3mssC-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.74A 3mssC-4xeyB:
35.3		 3mssC-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 VAL B 308
VAL B 318
ILE B 332
MET B 337
 None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.57A 3mssC-4xeyB:
35.3		 3mssC-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.74A 3mssD-4xeyB:
35.4		 3mssD-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.91A 3mssD-4xeyB:
35.4		 3mssD-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 6 VAL B 275
LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 ( 4.9A)
1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.75A 3mssD-4xeyB:
35.4		 3mssD-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 6 VAL B 275
VAL B 308
VAL B 318
ILE B 332
MET B 337
 1N1  B 601 ( 4.9A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
None
 0.60A 3mssD-4xeyB:
35.4		 3mssD-4xeyB:
71.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.51A 3octA-4xeyB:
13.6		 3octA-4xeyB:
33.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
THR B 334
GLY B 340
GLU B 348
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 1.11A 3octA-4xeyB:
13.6		 3octA-4xeyB:
33.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.59A 3oezA-4xeyB:
24.4		 3oezA-4xeyB:
36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.59A 3oezA-4xeyB:
24.4		 3oezA-4xeyB:
36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
LYS B 290
VAL B 308
MET B 309
ILE B 332
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-3.7A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.53A 3oezB-4xeyB:
25.1		 3oezB-4xeyB:
36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 ALA B 288
MET B 309
ILE B 312
LEU B 317
VAL B 318
THR B 334
GLY B 340
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
 0.56A 3oxzA-4xeyB:
30.8		 3oxzA-4xeyB:
93.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 9 LEU B 267
LYS B 290
VAL B 308
ILE B 332
VAL B 398
 1N1  B 601 (-3.7A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-4.1A)
None
 0.84A 3oxzA-4xeyB:
30.8		 3oxzA-4xeyB:
93.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 308
ILE B 332
MET B 337
LEU B 389
VAL B 398
 1N1  B 601 (-3.7A)
None
1N1  B 601 (-4.1A)
None
1N1  B 601 (-4.3A)
None
 0.50A 3oxzA-4xeyB:
30.8		 3oxzA-4xeyB:
93.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.57A 3pyyA-4xeyB:
29.9		 3pyyA-4xeyB:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
THR B 334
PHE B 336
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
 0.70A 3pyyA-4xeyB:
29.9		 3pyyA-4xeyB:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LYS B 290
VAL B 308
VAL B 318
ILE B 332
 1N1  B 601 (-4.6A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
 0.97A 3pyyA-4xeyB:
29.9		 3pyyA-4xeyB:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.72A 3pyyB-4xeyB:
31.0		 3pyyB-4xeyB:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.66A 3pyyB-4xeyB:
31.0		 3pyyB-4xeyB:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.45A 3qlgA-4xeyB:
32.4		 3qlgA-4xeyB:
36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
LYS B 290
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.60A 3qlgA-4xeyB:
32.4		 3qlgA-4xeyB:
36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_B_1N1B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.44A 3qlgB-4xeyB:
27.3		 3qlgB-4xeyB:
36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.57A 3sxrA-4xeyB:
33.4		 3sxrA-4xeyB:
30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.44A 3sxrA-4xeyB:
33.4		 3sxrA-4xeyB:
30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.53A 3sxrB-4xeyB:
33.7		 3sxrB-4xeyB:
30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
VAL B 318
THR B 334
GLY B 340
LEU B 389
PHE B 401
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
None
 0.86A 3sxrB-4xeyB:
33.7		 3sxrB-4xeyB:
30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_A_DB8A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
ALA B 288
LYS B 290
VAL B 318
ILE B 332
THR B 334
PHE B 336
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.38A 3ue4A-4xeyB:
34.3		 3ue4A-4xeyB:
93.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_B_DB8B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
PHE B 336
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.33A 3ue4B-4xeyB:
40.5		 3ue4B-4xeyB:
93.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG2_A_IREA1_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 337
GLY B 340
ASP B 344
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.61A 3ug2A-4xeyB:
28.5		 3ug2A-4xeyB:
28.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZBF_A_VGHA3000_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 12 LEU B 267
ALA B 288
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.30A 3zbfA-4xeyB:
32.7		 3zbfA-4xeyB:
33.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 LEU B 267
ALA B 288
LYS B 290
THR B 334
HIS B 380
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.81A 3zosA-4xeyB:
29.8		 3zosA-4xeyB:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
VAL B 318
PHE B 336
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.74A 4ag8A-4xeyB:
26.2		 4ag8A-4xeyB:
29.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGD_A_B49A2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 11 LEU B 267
ALA B 288
LYS B 290
PHE B 336
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.68A 4agdA-4xeyB:
30.9		 4agdA-4xeyB:
32.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGD_A_B49A2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 11 LEU B 267
ALA B 288
VAL B 318
PHE B 336
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.56A 4agdA-4xeyB:
30.9		 4agdA-4xeyB:
32.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
ALA B 288
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.67A 4anqA-4xeyB:
25.6		 4anqA-4xeyB:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
ALA B 288
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.36A 4anqA-4xeyB:
25.6		 4anqA-4xeyB:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
ALA B 288
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.65A 4ansA-4xeyB:
25.5		 4ansA-4xeyB:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
ALA B 288
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.34A 4ansA-4xeyB:
25.5		 4ansA-4xeyB:
32.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 VAL B 275
ALA B 288
MET B 309
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.88A 4bkjB-4xeyB:
30.1		 4bkjB-4xeyB:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
LYS B 290
ILE B 332
THR B 334
HIS B 380
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.64A 4c8bA-4xeyB:
26.1		 4c8bA-4xeyB:
24.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 VAL B 275
ALA B 288
MET B 309
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.56A 4csvA-4xeyB:
27.2		 4csvA-4xeyB:
48.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HJO_A_AQ4A1001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
THR B 334
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.42A 4hjoA-4xeyB:
30.3		 4hjoA-4xeyB:
28.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 309
VAL B 318
ILE B 332
THR B 334
GLY B 340
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
 0.66A 4mxoA-4xeyB:
33.6		 4mxoA-4xeyB:
36.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.47A 4mxoB-4xeyB:
33.1		 4mxoB-4xeyB:
36.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
ALA B 288
LYS B 290
MET B 309
VAL B 318
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.73A 4mxxA-4xeyB:
33.2		 4mxxA-4xeyB:
36.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
ALA B 288
LYS B 290
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.49A 4mxxA-4xeyB:
33.2		 4mxxA-4xeyB:
36.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
VAL B 318
THR B 334
MET B 337
GLY B 340
LEU B 389
PHE B 401
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
None
 0.57A 4mxxB-4xeyB:
32.5		 4mxxB-4xeyB:
36.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 LEU B 267
VAL B 275
ALA B 288
VAL B 318
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.51A 4mxyB-4xeyB:
26.8		 4mxyB-4xeyB:
35.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 LEU B 267
VAL B 275
ALA B 288
VAL B 318
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.51A 4mxzB-4xeyB:
26.8		 4mxzB-4xeyB:
35.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 VAL B 275
ALA B 288
LYS B 290
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.3A)
 0.52A 4o0uA-4xeyB:
8.2		 4o0uA-4xeyB:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3oht P38A
(Salmo
salar) 		5 / 12 LEU A  87
LEU A  76
GLY A  86
VAL A  53
THR A 351
 None
1N1  A1000 (-4.7A)
None
None
None
 1.41A 4oktA-3ohtA:
undetectable		 4oktA-3ohtA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
LYS B 290
VAL B 318
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.55A 4otwA-4xeyB:
25.7		 4otwA-4xeyB:
27.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 VAL B 275
ALA B 288
LYS B 290
MET B 309
THR B 334
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
 0.55A 4r7iA-4xeyB:
31.4		 4r7iA-4xeyB:
31.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 3oht P38A
(Salmo
salar) 		5 / 10 ALA A  52
LYS A  54
ILE A  85
THR A 107
LEU A 109
 1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
 0.43A 4rz7A-3ohtA:
17.0		 4rz7A-3ohtA:
18.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
LYS B 290
PHE B 336
MET B 337
ASN B 387
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.2A)
None
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.73A 4twpA-4xeyB:
34.2		 4twpA-4xeyB:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
PHE B 336
MET B 337
GLY B 340
ASN B 387
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.58A 4twpA-4xeyB:
34.2		 4twpA-4xeyB:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
LYS B 290
PHE B 336
MET B 337
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.77A 4twpB-4xeyB:
33.1		 4twpB-4xeyB:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
PHE B 336
MET B 337
GLY B 340
ASN B 387
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.62A 4twpB-4xeyB:
33.1		 4twpB-4xeyB:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
LYS B 290
PHE B 336
MET B 337
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.76A 4twpB-4xeyB:
33.1		 4twpB-4xeyB:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
PHE B 336
MET B 337
GLY B 340
ASN B 387
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.58A 4twpB-4xeyB:
33.1		 4twpB-4xeyB:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 ALA B 288
MET B 309
ILE B 312
HIS B 380
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.61A 4tyjA-4xeyB:
32.4		 4tyjA-4xeyB:
32.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 11 LEU B 267
VAL B 275
ALA B 288
MET B 337
GLY B 340
ASN B 387
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.53A 4u5jA-4xeyB:
34.3		 4u5jA-4xeyB:
36.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
ALA B 288
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.27A 4u5jB-4xeyB:
28.1		 4u5jB-4xeyB:
36.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3oht P38A
(Salmo
salar) 		4 / 7 VAL A  39
LYS A  54
ILE A  85
ILE A 167
 1N1  A1000 (-4.6A)
1N1  A1000 (-4.5A)
1N1  A1000 ( 4.1A)
None
 0.66A 4uxqA-3ohtA:
17.2		 4uxqA-3ohtA:
26.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 ALA B 288
MET B 309
ILE B 312
LEU B 373
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
None
None
1N1  B 601 (-3.5A)
 0.92A 4v01A-4xeyB:
31.2		 4v01A-4xeyB:
31.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 12 ALA B 288
MET B 309
LEU B 373
HIS B 380
ALA B 399
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-3.5A)
 0.78A 4v01B-4xeyB:
31.4		 4v01B-4xeyB:
31.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 11 LEU B 267
ALA B 288
LYS B 290
THR B 334
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.72A 4wa9A-4xeyB:
37.7		 4wa9A-4xeyB:
78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 11 LEU B 267
ALA B 288
THR B 334
MET B 337
GLY B 340
ASN B 387
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.46A 4wa9A-4xeyB:
37.7		 4wa9A-4xeyB:
78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 11 LEU B 267
ALA B 288
THR B 334
MET B 337
GLY B 340
LEU B 389
ALA B 399
PHE B 401
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
None
 0.76A 4wa9A-4xeyB:
37.7		 4wa9A-4xeyB:
78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
THR B 334
PHE B 336
MET B 337
GLY B 340
ASN B 387
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.48A 4wa9B-4xeyB:
40.8		 4wa9B-4xeyB:
78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
THR B 334
PHE B 336
MET B 337
GLY B 340
LEU B 389
ALA B 399
PHE B 401
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
None
 1.09A 4wa9B-4xeyB:
40.8		 4wa9B-4xeyB:
78.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 6 LEU B 267
ALA B 288
MET B 337
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.60A 4wboC-4xeyB:
22.4		 4wboC-4xeyB:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WKQ_A_IREA1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
ALA B 288
LYS B 290
MET B 309
THR B 334
GLY B 340
ASP B 344
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.73A 4wkqA-4xeyB:
33.7		 4wkqA-4xeyB:
28.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
ALA B 288
LYS B 290
MET B 309
VAL B 318
THR B 334
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.55A 4xliA-4xeyB:
32.5		 4xliA-4xeyB:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
ALA B 288
MET B 309
VAL B 318
THR B 334
MET B 337
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.40A 4xliA-4xeyB:
32.5		 4xliA-4xeyB:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		10 / 12 LEU B 267
ALA B 288
LYS B 290
MET B 309
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.65A 4xliB-4xeyB:
38.9		 4xliB-4xeyB:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 9 LEU B 267
VAL B 275
ALA B 288
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.36A 5aaaA-4xeyB:
31.0		 5aaaA-4xeyB:
32.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 10 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.41A 5aabA-4xeyB:
24.8		 5aabA-4xeyB:
32.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAC_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 10 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.46A 5aacA-4xeyB:
24.7		 5aacA-4xeyB:
31.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
ALA B 288
LYS B 290
PHE B 336
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.76A 5ajqA-4xeyB:
23.3		 5ajqA-4xeyB:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
ALA B 288
PHE B 336
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.76A 5ajqA-4xeyB:
23.3		 5ajqA-4xeyB:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 309
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.78A 5bvwA-4xeyB:
30.4		 5bvwA-4xeyB:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
THR B 334
GLY B 340
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
 0.62A 5h2uA-4xeyB:
30.9		 5h2uA-4xeyB:
29.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
VAL B 275
ALA B 288
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.46A 5h2uA-4xeyB:
30.9		 5h2uA-4xeyB:
29.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_C_1N1C501_1
(PROTEIN-TYROSINE
KINASE 6)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
ALA B 288
ILE B 332
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.52A 5h2uC-4xeyB:
30.8		 5h2uC-4xeyB:
29.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_C_1N1C501_1
(PROTEIN-TYROSINE
KINASE 6)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
ALA B 288
LYS B 290
ILE B 332
THR B 334
GLY B 340
 1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
 0.61A 5h2uC-4xeyB:
30.8		 5h2uC-4xeyB:
29.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_D_1N1D504_1
(PROTEIN-TYROSINE
KINASE 6)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
VAL B 275
ALA B 288
ILE B 332
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.38A 5h2uD-4xeyB:
25.5		 5h2uD-4xeyB:
29.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_D_1N1D504_1
(PROTEIN-TYROSINE
KINASE 6)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
VAL B 275
ALA B 288
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.44A 5h2uD-4xeyB:
25.5		 5h2uD-4xeyB:
29.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 12 VAL B 275
ALA B 288
ILE B 332
THR B 334
ASP B 344
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
None
 0.59A 5hesA-4xeyB:
25.9		 5hesA-4xeyB:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 VAL B 275
ALA B 288
LYS B 290
ILE B 332
THR B 334
ASP B 344
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
None
 0.65A 5hesB-4xeyB:
25.9		 5hesB-4xeyB:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 12 VAL B 275
ALA B 288
LYS B 290
ILE B 332
THR B 334
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
 0.33A 5hieA-4xeyB:
26.6		 5hieA-4xeyB:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 12 VAL B 275
ALA B 288
LYS B 290
ILE B 332
THR B 334
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
 0.34A 5hieB-4xeyB:
26.6		 5hieB-4xeyB:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 12 VAL B 275
ALA B 288
LYS B 290
ILE B 332
THR B 334
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
 0.32A 5hieD-4xeyB:
26.6		 5hieD-4xeyB:
25.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 ALA B 288
ILE B 332
THR B 334
GLY B 340
GLU B 348
LEU B 389
 1N1  B 601 (-3.5A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.52A 5i9xA-4xeyB:
32.2		 5i9xA-4xeyB:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
LYS B 290
MET B 309
THR B 334
GLY B 340
GLU B 348
LEU B 389
 1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
 0.69A 5i9yA-4xeyB:
25.2		 5i9yA-4xeyB:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3oht P38A
(Salmo
salar) 		5 / 9 GLY A  32
VAL A  39
ALA A  52
ILE A  85
MET A 110
 1N1  A1000 (-3.4A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 ( 4.1A)
None
 0.67A 5lw1B-3ohtA:
29.9		 5lw1B-3ohtA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3oht P38A
(Salmo
salar) 		6 / 10 GLY A  32
VAL A  39
ALA A  52
ILE A  85
LEU A 109
LEU A 168
 1N1  A1000 (-3.4A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-4.7A)
1N1  A1000 ( 3.7A)
 1.01A 5lw1E-3ohtA:
17.1		 5lw1E-3ohtA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3oht P38A
(Salmo
salar) 		6 / 10 GLY A  32
VAL A  39
ALA A  52
ILE A  85
LEU A 109
MET A 110
 1N1  A1000 (-3.4A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-4.7A)
None
 0.76A 5lw1E-3ohtA:
17.1		 5lw1E-3ohtA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3oht P38A
(Salmo
salar) 		5 / 9 GLY A  32
VAL A  39
ALA A  52
LEU A 109
LEU A 168
 1N1  A1000 (-3.4A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.7A)
1N1  A1000 ( 3.7A)
 0.79A 5lw1H-3ohtA:
30.0		 5lw1H-3ohtA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3oht P38A
(Salmo
salar) 		5 / 9 GLY A  32
VAL A  39
ALA A  52
LEU A 109
MET A 110
 1N1  A1000 (-3.4A)
1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.7A)
None
 0.58A 5lw1H-3ohtA:
30.0		 5lw1H-3ohtA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MO4_A_NILA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 10 LEU B 267
VAL B 275
ILE B 332
PHE B 336
MET B 337
GLY B 340
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-4.1A)
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
 0.78A 5mo4A-4xeyB:
28.4		 5mo4A-4xeyB:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
VAL B 308
MET B 309
ILE B 312
LEU B 317
HIS B 380
LEU B 389
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
None
None
1N1  B 601 (-4.3A)
 0.67A 5mo4A-4xeyB:
28.4		 5mo4A-4xeyB:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
VAL B 308
MET B 309
LEU B 317
HIS B 380
LEU B 389
ALA B 399
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.60A 5mo4A-4xeyB:
28.4		 5mo4A-4xeyB:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 ALA B 288
VAL B 308
MET B 309
LEU B 317
VAL B 318
HIS B 380
LEU B 389
 1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
None
1N1  B 601 (-4.3A)
 0.65A 5mo4A-4xeyB:
28.4		 5mo4A-4xeyB:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5P9I_A_1E8A701_1
(TYROSINE-PROTEIN
KINASE BTK)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 VAL B 275
ALA B 288
LYS B 290
ILE B 332
THR B 334
GLY B 340
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.60A 5p9iA-4xeyB:
25.2		 5p9iA-4xeyB:
35.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 ALA B 288
MET B 309
VAL B 318
PHE B 336
GLY B 340
LEU B 389
 1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.58A 5te0A-4xeyB:
24.0		 5te0A-4xeyB:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_1
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3oht P38A
(Salmo
salar) 		6 / 12 ALA A  52
LYS A  54
GLU A  72
LEU A 105
THR A 107
GLY A 111
 1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.2A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
 0.50A 5vcvA-3ohtA:
18.2		 5vcvA-3ohtA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_1
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3oht P38A
(Salmo
salar) 		7 / 12 VAL A  39
ALA A  52
LYS A  54
GLU A  72
LEU A 105
THR A 107
GLY A 111
 1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 (-4.2A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
 0.66A 5vcyA-3ohtA:
17.9		 5vcyA-3ohtA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		6 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
GLY B 340
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.5A)
 0.77A 5zv2A-4xeyB:
31.7		 5zv2A-4xeyB:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3oht P38A
(Salmo
salar) 		8 / 12 VAL A  39
ALA A  52
LYS A  54
GLU A  72
ILE A  85
THR A 107
GLY A 111
ASP A 169
 1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
1N1  A1000 (-4.7A)
1N1  A1000 (-3.4A)
 0.73A 6bsdA-3ohtA:
8.3		 6bsdA-3ohtA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3oht P38A
(Salmo
salar) 		8 / 12 VAL A  39
ALA A  52
LYS A  54
GLU A  72
ILE A  85
THR A 107
MET A 110
ASP A 169
 1N1  A1000 (-4.6A)
1N1  A1000 (-3.7A)
1N1  A1000 (-4.5A)
1N1  A1000 (-4.2A)
1N1  A1000 ( 4.1A)
1N1  A1000 (-3.3A)
None
1N1  A1000 (-3.4A)
 0.60A 6bsdA-3ohtA:
8.3		 6bsdA-3ohtA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 VAL B 275
ALA B 288
MET B 309
THR B 334
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.57A 6bsdA-4xeyB:
24.3		 6bsdA-4xeyB:
12.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FNM_A_1N1A1001_1
(-)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
LYS B 290
ILE B 332
THR B 334
MET B 337
GLY B 340
LEU B 389
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
None
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
 0.43A 6fnmA-4xeyB:
27.1		 6fnmA-4xeyB:
32.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
LYS B 290
MET B 309
ILE B 312
VAL B 318
ILE B 332
THR B 334
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
 0.67A 6hd4A-4xeyB:
27.9		 6hd4A-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
ILE B 332
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.75A 6hd4A-4xeyB:
27.9		 6hd4A-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 5 VAL B 308
PHE B 336
MET B 337
GLY B 340
 None
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
 0.35A 6hd4A-4xeyB:
27.9		 6hd4A-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 VAL B 275
ALA B 288
LYS B 290
MET B 309
ILE B 312
VAL B 318
ILE B 332
THR B 334
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
 0.73A 6hd4B-4xeyB:
34.1		 6hd4B-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
ILE B 332
THR B 334
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.74A 6hd4B-4xeyB:
34.1		 6hd4B-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		5 / 6 LEU B 267
VAL B 308
PHE B 336
MET B 337
GLY B 340
 1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.2A)
None
1N1  B 601 (-3.5A)
 0.74A 6hd4B-4xeyB:
34.1		 6hd4B-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		7 / 12 VAL B 275
ALA B 288
LYS B 290
MET B 309
VAL B 318
ILE B 332
THR B 334
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
 0.62A 6hd6A-4xeyB:
34.3		 6hd6A-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 VAL B 275
ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
PHE B 336
LEU B 389
ALA B 399
 1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.63A 6hd6A-4xeyB:
34.3		 6hd6A-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		4 / 5 LEU B 267
ILE B 312
MET B 337
GLY B 340
 1N1  B 601 (-3.7A)
None
None
1N1  B 601 (-3.5A)
 0.98A 6hd6A-4xeyB:
34.3		 6hd6A-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		8 / 12 LEU B 267
VAL B 275
ALA B 288
LYS B 290
MET B 309
ILE B 312
VAL B 318
THR B 334
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.6A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
 0.83A 6hd6B-4xeyB:
34.1		 6hd6B-4xeyB:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens) 		9 / 12 LEU B 267
VAL B 275
ALA B 288
MET B 309
ILE B 312
VAL B 318
THR B 334
PHE B 336
LEU B 389
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
None
1N1  B 601 ( 4.3A)
1N1  B 601 (-3.3A)
1N1  B 601 ( 4.2A)
1N1  B 601 (-4.3A)
 0.83A 6hd6B-4xeyB:
34.1		 6hd6B-4xeyB:
40.64