SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1GA'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_B_ROCB201_2 (HIV-1 PROTEASE)	4di5	5-EPI-ARISTOLOCHENE SYNTHASE (Nicotiana tabacum)	3 / 3	ARG A 264 VAL A 533 THR A 519	1GA A 603 ( 3.6A) None None	0.84A	3k4vA-4di5A: undetectable	3k4vA-4di5A: 10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_A_OBNA1104_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	4di5	5-EPI-ARISTOLOCHENE SYNTHASE (Nicotiana tabacum)	5 / 12	LEU A 512 GLY A 276 ALA A 274 PHE A 272 ILE A 294	None None None None 1GA A 603 (-4.1A)	1.10A	4hytA-4di5A: undetectable	4hytA-4di5A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_C_OBNC2004_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	4di5	5-EPI-ARISTOLOCHENE SYNTHASE (Nicotiana tabacum)	5 / 12	LEU A 512 GLY A 276 ALA A 274 PHE A 272 ILE A 294	None None None None 1GA A 603 (-4.1A)	1.11A	4hytC-4di5A: undetectable	4hytC-4di5A: 20.28