SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1EY'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 4inw PHEROMONE-BINDING
PROTEIN 1
(Amyelois
transitella) 		3 / 3 MET A   5
LEU A   8
SER A   9
 1EY  A 201 (-4.6A)
1EY  A 201 (-3.9A)
None
 0.61A 1ee2A-4inwA:
undetectable		 1ee2A-4inwA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 4inw PHEROMONE-BINDING
PROTEIN 1
(Amyelois
transitella) 		4 / 4 LYS A  20
LEU A  16
LEU A  55
SER A  56
 None
None
None
1EY  A 201 (-3.5A)
 1.25A 1tt6A-4inwA:
undetectable		 1tt6A-4inwA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 4inw PHEROMONE-BINDING
PROTEIN 1
(Amyelois
transitella) 		5 / 12 ALA A  15
GLY A  13
LEU A  16
PHE A  33
VAL A 111
 None
None
None
None
1EY  A 201 (-4.0A)
 1.21A 1vpoH-4inwA:
undetectable
1vpoL-4inwA:
undetectable		 1vpoH-4inwA:
18.40
1vpoL-4inwA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4inw PHEROMONE-BINDING
PROTEIN 1
(Amyelois
transitella) 		3 / 3 LEU A 112
MET A 109
MET A  61
 None
None
1EY  A 201 ( 4.2A)
 1.02A 2vavF-4inwA:
undetectable		 2vavF-4inwA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4inw PHEROMONE-BINDING
PROTEIN 1
(Amyelois
transitella) 		4 / 7 PHE A  12
MET A   5
VAL A 134
TRP A  37
 1EY  A 201 (-3.4A)
1EY  A 201 (-4.6A)
None
None
 1.47A 5ad4A-4inwA:
undetectable
5ad4B-4inwA:
undetectable		 5ad4A-4inwA:
15.40
5ad4B-4inwA:
15.40