SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1EU'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1AJ6_A_NOVA1_1 (GYRASE) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 9 | ASN A 42GLU A 46ASP A 69ARG A 72PRO A 75ALA A 86ILE A 90THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-4.5A)1EU A 2 (-3.7A) | 0.69A | 1aj6A-3fv5A:26.7 | 1aj6A-3fv5A:47.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KIJ_A_NOVA400_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | ASP A 45GLU A 46ASP A 69ARG A 72PRO A 75ILE A 90ARG A 132THR A 163 | None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.56A | 1kijA-3fv5A:27.2 | 1kijA-3fv5A:29.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KIJ_A_NOVA400_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | GLU A 46ASP A 69ARG A 72PRO A 75ASP A 77ILE A 90ARG A 132THR A 163 | 1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.95A | 1kijA-3fv5A:27.2 | 1kijA-3fv5A:29.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KIJ_B_NOVB444_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 9 / 12 | ASN A 42GLU A 46ASP A 69ARG A 72PRO A 75ASP A 77ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.91A | 1kijB-3fv5A:27.6 | 1kijB-3fv5A:29.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1S14_A_NOVA1300_1 (TOPOISOMERASE IVSUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 11 / 12 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.38A | 1s14A-3fv5A:29.5 | 1s14A-3fv5A:88.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1S14_A_NOVA1300_1 (TOPOISOMERASE IVSUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 11 / 12 | ASN A 42SER A 43GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ASP A 77ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)None1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.72A | 1s14A-3fv5A:29.5 | 1s14A-3fv5A:88.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1S14_B_NOVB2300_1 (TOPOISOMERASE IVSUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 11 / 12 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ALA A 86ILE A 90ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)None1EU A 2 (-4.5A)1EU A 2 (-3.9A) | 0.45A | 1s14B-3fv5A:32.1 | 1s14B-3fv5A:88.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1S14_B_NOVB2300_1 (TOPOISOMERASE IVSUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 11 / 12 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ASP A 77ILE A 90ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)None1EU A 2 (-4.5A)1EU A 2 (-3.9A) | 0.77A | 1s14B-3fv5A:32.1 | 1s14B-3fv5A:88.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3LPS_A_NOVA901_1 (TOPOISOMERASE IVSUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 11 / 12 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.54A | 3lpsA-3fv5A:31.0 | 3lpsA-3fv5A:40.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3LPS_A_NOVA901_1 (TOPOISOMERASE IVSUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 9 / 12 | SER A 43GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ASP A 77ARG A 132THR A 163 | 1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)None1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 1.01A | 3lpsA-3fv5A:31.0 | 3lpsA-3fv5A:40.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_A_NOVA2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 9 / 11 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.81A | 4urnA-3fv5A:28.1 | 4urnA-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_A_NOVA2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 10 / 11 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.66A | 4urnA-3fv5A:28.1 | 4urnA-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_A_NOVA2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 5 / 11 | ASP A 45GLU A 46ASP A 69ILE A 116THR A 163 | None1EU A 2 (-3.4A)1EU A 2 (-3.3A)None1EU A 2 (-3.7A) | 1.31A | 4urnA-3fv5A:28.1 | 4urnA-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_B_NOVB2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 10 / 11 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.57A | 4urnB-3fv5A:26.5 | 4urnB-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_B_NOVB2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 10 / 11 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72PRO A 75ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.69A | 4urnB-3fv5A:26.5 | 4urnB-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_B_NOVB2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 5 / 11 | ASP A 45GLU A 46ASP A 69ILE A 116THR A 163 | None1EU A 2 (-3.4A)1EU A 2 (-3.3A)None1EU A 2 (-3.7A) | 1.44A | 4urnB-3fv5A:26.5 | 4urnB-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_C_NOVC2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 11 / 11 | ASN A 42SER A 43ASP A 45GLU A 46ASP A 69ARG A 72MET A 74PRO A 75ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)None1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.4A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.64A | 4urnC-3fv5A:28.5 | 4urnC-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URN_C_NOVC2000_1 (DNA TOPOISOMERASEIV, B SUBUNIT) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 5 / 11 | ASP A 45GLU A 46ASP A 69ILE A 116THR A 163 | None1EU A 2 (-3.4A)1EU A 2 (-3.3A)None1EU A 2 (-3.7A) | 1.42A | 4urnC-3fv5A:28.5 | 4urnC-3fv5A:45.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_A_NOVA2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | ASN A 42SER A 43GLU A 46ASP A 69ARG A 72PRO A 75ASP A 77ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-3.9A) | 1.05A | 4uroA-3fv5A:28.0 | 4uroA-3fv5A:46.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_A_NOVA2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | ASN A 42SER A 43GLU A 46ASP A 69ARG A 72PRO A 75ILE A 90ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A) | 0.69A | 4uroA-3fv5A:28.0 | 4uroA-3fv5A:46.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_B_NOVB2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | ASN A 42SER A 43GLU A 46ASP A 69ARG A 72PRO A 75ASP A 77ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-3.9A) | 1.03A | 4uroB-3fv5A:28.3 | 4uroB-3fv5A:46.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_B_NOVB2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | ASN A 42SER A 43GLU A 46ASP A 69ARG A 72PRO A 75ILE A 90ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A) | 0.64A | 4uroB-3fv5A:28.3 | 4uroB-3fv5A:46.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_C_NOVC2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | ASN A 42GLU A 46ASP A 69ARG A 72PRO A 75ALA A 86ILE A 90ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-4.5A)1EU A 2 (-3.9A) | 0.63A | 4uroC-3fv5A:28.5 | 4uroC-3fv5A:46.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_C_NOVC2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 7 / 12 | ASN A 42GLU A 46ASP A 69ARG A 72PRO A 75ASP A 77ARG A 132 | 1EU A 2 (-4.9A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-3.9A) | 1.16A | 4uroC-3fv5A:28.5 | 4uroC-3fv5A:46.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_D_NOVD2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 9 / 12 | ASN A 42SER A 43GLU A 46ASP A 69ARG A 72PRO A 75ILE A 90ARG A 132THR A 163 | 1EU A 2 (-4.9A)1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)1EU A 2 (-4.5A)1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.62A | 4uroD-3fv5A:27.8 | 4uroD-3fv5A:46.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4URO_D_NOVD2000_1 (DNA GYRASE SUBUNIT B) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 8 / 12 | SER A 43GLU A 46ASP A 69ARG A 72PRO A 75ASP A 77ARG A 132THR A 163 | 1EU A 2 (-3.0A)1EU A 2 (-3.4A)1EU A 2 (-3.3A)1EU A 2 (-3.3A)1EU A 2 (-4.2A)None1EU A 2 (-3.9A)1EU A 2 (-3.7A) | 0.97A | 4uroD-3fv5A:27.8 | 4uroD-3fv5A:46.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5NY7_A_NCAA303_0 (AMIDASE) |
3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) | 4 / 6 | ARG A 72PRO A 75THR A 163GLU A 46 | 1EU A 2 (-3.3A)1EU A 2 (-4.2A)1EU A 2 (-3.7A)1EU A 2 (-3.4A) | 1.07A | 5ny7A-3fv5A:2.0 | 5ny7A-3fv5A:20.73 |