SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1DF'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SG9_B_KANB305_1 (APH(2'')-ID)	4ng3	5-CARBOXYVANILLATE DECARBOXYLASE (Sphingomonas paucimobilis)	4 / 8	ASN A 143 SER A 271 HIS A 226 GLU A 8	None None 1DF A 402 (-4.2A) None	1.04A	3sg9B-4ng3A: undetectable	3sg9B-4ng3A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_0U9A601_1 (CHOLESTEROL 24-HYDROXYLASE)	4ng3	5-CARBOXYVANILLATE DECARBOXYLASE (Sphingomonas paucimobilis)	5 / 12	LEU A 34 VAL A 38 ARG A 175 THR A 11 ALA A 77	1DF A 402 (-4.5A) None None None 1DF A 402 (-3.7A)	1.28A	4fiaA-4ng3A: undetectable	4fiaA-4ng3A: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_198A602_1 (CHOLESTEROL 24-HYDROXYLASE)	4ng3	5-CARBOXYVANILLATE DECARBOXYLASE (Sphingomonas paucimobilis)	5 / 12	LEU A 34 VAL A 38 ARG A 175 THR A 11 ALA A 77	1DF A 402 (-4.5A) None None None 1DF A 402 (-3.7A)	1.28A	4fiaA-4ng3A: undetectable	4fiaA-4ng3A: 22.02