SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1DA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		7 / 7 ASP A 210
PHE A 213
ASN A 215
TRP A 217
PHE A 254
SER A 269
ARG A 270
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
1DA  A 301 (-3.3A)
None
None
 0.72A 1rqpB-5lmzA:
43.1		 1rqpB-5lmzA:
87.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		8 / 8 ASP A 210
PHE A 213
ASN A 215
TRP A 217
PHE A 254
SER A 269
ARG A 270
ALA A 276
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
1DA  A 301 (-3.3A)
None
None
1DA  A 301 (-3.0A)
 0.68A 1rqpC-5lmzA:
42.8		 1rqpC-5lmzA:
87.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		8 / 8 ASP A 210
PHE A 213
ASN A 215
TRP A 217
PHE A 254
SER A 269
ARG A 270
ALA A 276
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
1DA  A 301 (-3.3A)
None
None
1DA  A 301 (-3.0A)
 0.64A 1rqpA-5lmzA:
43.0		 1rqpA-5lmzA:
87.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		7 / 8 ASP A 210
PHE A 213
ASN A 215
TRP A 217
PHE A 254
SER A 269
ALA A 276
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
1DA  A 301 (-3.3A)
None
1DA  A 301 (-3.0A)
 0.35A 2v7uA-5lmzA:
42.9		 2v7uA-5lmzA:
87.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		7 / 8 ASP A 210
PHE A 213
ASN A 215
TRP A 217
SER A 269
ARG A 270
ALA A 276
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
None
None
1DA  A 301 (-3.0A)
 0.73A 2v7uA-5lmzA:
42.9		 2v7uA-5lmzA:
87.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		6 / 7 ASP A 210
PHE A 213
ASN A 215
TRP A 217
PHE A 254
SER A 269
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
1DA  A 301 (-3.3A)
None
 0.38A 2v7uB-5lmzA:
42.9		 2v7uB-5lmzA:
87.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		6 / 7 ASP A 210
PHE A 213
ASN A 215
TRP A 217
SER A 269
ARG A 270
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
None
None
 0.81A 2v7uB-5lmzA:
42.9		 2v7uB-5lmzA:
87.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_B_SAMB1300_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		8 / 9 ASP A 210
PHE A 213
ASN A 215
TRP A 217
PHE A 254
SER A 269
ALA A 276
ASN A 278
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
1DA  A 301 (-3.3A)
None
1DA  A 301 (-3.0A)
1DA  A 301 ( 4.4A)
 0.35A 2v7uC-5lmzA:
42.9		 2v7uC-5lmzA:
87.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_B_SAMB1300_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		8 / 9 ASP A 210
PHE A 213
ASN A 215
TRP A 217
PHE A 254
SER A 269
ARG A 270
ALA A 276
 None
1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
None
1DA  A 301 (-3.3A)
None
None
1DA  A 301 (-3.0A)
 0.69A 2v7uC-5lmzA:
42.9		 2v7uC-5lmzA:
87.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_A_ADNA501_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		4 / 4 PHE A 213
ASN A 215
PHE A 254
ASN A 278
 1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
1DA  A 301 (-3.3A)
1DA  A 301 ( 4.4A)
 0.27A 2zbuA-5lmzA:
30.3		 2zbuA-5lmzA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_C_ADNC503_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		4 / 4 PHE A 213
ASN A 215
PHE A 254
ASN A 278
 1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
1DA  A 301 (-3.3A)
1DA  A 301 ( 4.4A)
 0.28A 2zbuC-5lmzA:
30.4		 2zbuC-5lmzA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 5lmz FLUORINASE
(Streptomyces
sp.
MA37) 		3 / 3 PHE A 213
ASN A 215
PHE A 254
 1DA  A 301 (-3.0A)
1DA  A 301 (-2.0A)
1DA  A 301 (-3.3A)
 0.25A 2zbuD-5lmzA:
30.3		 2zbuD-5lmzA:
29.17