SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1BO'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AC7_A_ADNA1216_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	3s3f	TYROSINE-PROTEIN PHOSPHATASE 10D (Drosophila melanogaster)	5 / 11	GLY A 272 VAL A 274 GLU A 52 ASP A 269 HIS A 34	None None 1BO A 308 ( 4.7A) None None	1.33A	2ac7A-3s3fA: undetectable 2ac7B-3s3fA: undetectable	2ac7A-3s3fA: 20.38 2ac7B-3s3fA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AC7_B_ADNB1215_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	3s3f	TYROSINE-PROTEIN PHOSPHATASE 10D (Drosophila melanogaster)	5 / 11	HIS A 34 GLY A 272 VAL A 274 GLU A 52 ASP A 269	None None None 1BO A 308 ( 4.7A) None	1.34A	2ac7A-3s3fA: undetectable 2ac7B-3s3fA: undetectable	2ac7A-3s3fA: 20.38 2ac7B-3s3fA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YSI_A_NCAA1001_0 (UBIQUITINATING/DEUBI QUITINATING ENZYME SDEA)	2huf	ALANINE GLYOXYLATE AMINOTRANSFERASE (Aedes aegypti)	4 / 6	ARG A 356 GLY A 24 SER A 155 THR A 316	1BO A 602 (-3.0A) None LLP A 206 (-2.8A) None	1.13A	5ysiA-2hufA: undetectable	5ysiA-2hufA: 17.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AC7_A_ADNA1216_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","3s3f","TYROSINE-PROTEIN PHOSPHATASE 10D","Drosophila melanogaster",5,"GLY A 272;VAL A 274;GLU A  52;ASP A 269;HIS A  34","None;None;1BO A 308 ( 4.7A);None;None","1.33A","2ac7A-3s3fA:undetectable;2ac7B-3s3fA:undetectable",null],["2AC7_B_ADNB1215_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","3s3f","TYROSINE-PROTEIN PHOSPHATASE 10D","Drosophila melanogaster",5,"HIS A  34;GLY A 272;VAL A 274;GLU A  52;ASP A 269","None;None;None;1BO A 308 ( 4.7A);None","1.34A","2ac7A-3s3fA:undetectable;2ac7B-3s3fA:undetectable","2ac7A-3s3fA:20.38;2ac7B-3s3fA:20.38"],["5YSI_A_NCAA1001_0","UBIQUITINATING\/DEUBIQUITINATING ENZYME SDEA","2huf","ALANINE GLYOXYLATE AMINOTRANSFERASE","Aedes aegypti",4,"ARG A 356;GLY A  24;SER A 155;THR A 316","1BO A 602 (-3.0A);None;LLP A 206 (-2.8A);None","1.13A","5ysiA-2hufA:undetectable","2ac7A-3s3fA:20.38;2ac7B-3s3fA:20.38"]]