SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1BN'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N2O_C_AG2C1002_1 (BIOSYNTHETIC ARGININE DECARBOXYLASE)	3pb9	GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIK E PROTEIN (Homo sapiens)	4 / 8	ASP X 186 LEU X 270 ASP X 326 ASP X 327	ZN X 400 ( 2.1A) 1BN X 390 ( 4.7A) 1BN X 390 ( 4.2A) None	1.21A	3n2oC-3pb9X: undetectable 3n2oD-3pb9X: undetectable	3n2oC-3pb9X: 20.57 3n2oD-3pb9X: 20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OI8_A_ADNA2_1 (UNCHARACTERIZED PROTEIN)	3pb9	GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIK E PROTEIN (Homo sapiens)	4 / 6	HIS X 351 PRO X 347 LEU X 270 ASP X 326	ZN X 400 ( 3.2A) None 1BN X 390 ( 4.7A) 1BN X 390 ( 4.2A)	1.10A	3oi8A-3pb9X: undetectable	3oi8A-3pb9X: 17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PQA_A_X8ZA401_1 (SUCCINYL-DIAMINOPIME LATE DESUCCINYLASE)	3pb9	GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIK E PROTEIN (Homo sapiens)	5 / 11	HIS X 168 ASP X 186 GLU X 225 GLU X 226 HIS X 351	None ZN X 400 ( 2.1A) 1BN X 390 (-3.6A) ZN X 400 ( 2.1A) ZN X 400 ( 3.2A)	0.32A	4pqaA-3pb9X: 22.5	4pqaA-3pb9X: 22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_F_PARF500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	3pb9	GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIK E PROTEIN (Homo sapiens)	5 / 11	PHE X 174 ASP X 269 ASP X 327 TYR X 238 GLY X 224	None 1BN X 390 (-3.3A) None None None	1.45A	4qb9F-3pb9X: 0.8	4qb9F-3pb9X: 23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWU_A_ACAA18_2 (WTFP-TAG,GP41)	3pb9	GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIK E PROTEIN (Homo sapiens)	3 / 3	LEU X 271 LEU X 270 TRP X 350	None 1BN X 390 ( 4.7A) 1BN X 390 (-4.8A)	0.94A	5nwuA-3pb9X: undetectable	5nwuA-3pb9X: 10.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3N2O_C_AG2C1002_1","BIOSYNTHETIC ARGININE DECARBOXYLASE;BIOSYNTHETIC ARGININE DECARBOXYLASE","3pb9","GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN","Homo sapiens",4,"ASP X 186;LEU X 270;ASP X 326;ASP X 327"," ZN X 400 ( 2.1A);1BN X 390 ( 4.7A);1BN X 390 ( 4.2A);None","1.21A","3n2oC-3pb9X:undetectable;3n2oD-3pb9X:undetectable",null],["3OI8_A_ADNA2_1","UNCHARACTERIZED PROTEIN","3pb9","GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN","Homo sapiens",4,"HIS X 351;PRO X 347;LEU X 270;ASP X 326"," ZN X 400 ( 3.2A);None;1BN X 390 ( 4.7A);1BN X 390 ( 4.2A)","1.10A","3oi8A-3pb9X:undetectable","3n2oC-3pb9X:20.57;3n2oD-3pb9X:20.57"],["4PQA_A_X8ZA401_1","SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE","3pb9","GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN","Homo sapiens",5,"HIS X 168;ASP X 186;GLU X 225;GLU X 226;HIS X 351","None; ZN X 400 ( 2.1A);1BN X 390 (-3.6A); ZN X 400 ( 2.1A); ZN X 400 ( 3.2A)","0.32A","4pqaA-3pb9X:22.5","3oi8A-3pb9X:17.26"],["4QB9_F_PARF500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","3pb9","GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN","Homo sapiens",5,"PHE X 174;ASP X 269;ASP X 327;TYR X 238;GLY X 224","None;1BN X 390 (-3.3A);None;None;None","1.45A","4qb9F-3pb9X:0.8","4pqaA-3pb9X:22.49"],["5NWU_A_ACAA18_2","WTFP-TAG,GP41","3pb9","GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN","Homo sapiens",3,"LEU X 271;LEU X 270;TRP X 350","None;1BN X 390 ( 4.7A);1BN X 390 (-4.8A)","0.94A","5nwuA-3pb9X:undetectable","4qb9F-3pb9X:23.27"]]