SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1BH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 11 GLY A  65
HIS A  64
HIS A  67
ILE A  30
GLY A 219
 None
1BH  A 300 ( 3.0A)
None
None
1BH  A 300 (-3.5A)
 1.13A 1gtfS-1bh6A:
undetectable
1gtfT-1bh6A:
undetectable		 1gtfS-1bh6A:
12.69
1gtfT-1bh6A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 11 GLY A  65
HIS A  64
HIS A  67
ILE A  30
GLY A 219
 None
1BH  A 300 ( 3.0A)
None
None
1BH  A 300 (-3.5A)
 1.13A 1utdS-1bh6A:
undetectable
1utdT-1bh6A:
undetectable		 1utdS-1bh6A:
12.69
1utdT-1bh6A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 LEU A 126
ILE A  31
SER A 109
SER A 105
GLY A 110
 1BH  A 300 (-4.0A)
None
None
None
None
 1.39A 3ijxB-1bh6A:
undetectable
3ijxD-1bh6A:
undetectable		 3ijxB-1bh6A:
22.45
3ijxD-1bh6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 LEU A 126
ILE A  31
SER A 109
SER A 105
GLY A 110
 1BH  A 300 (-4.0A)
None
None
None
None
 1.38A 3ik6B-1bh6A:
0.0
3ik6E-1bh6A:
0.0		 3ik6B-1bh6A:
22.45
3ik6E-1bh6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 LEU A 126
ILE A  31
SER A 109
SER A 105
GLY A 110
 1BH  A 300 (-4.0A)
None
None
None
None
 1.34A 3iluB-1bh6A:
0.0
3iluE-1bh6A:
0.0		 3iluB-1bh6A:
22.45
3iluE-1bh6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.05A 3ln1A-1bh6A:
undetectable		 3ln1A-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.04A 3ln1B-1bh6A:
undetectable		 3ln1B-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.04A 3ln1C-1bh6A:
0.0		 3ln1C-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.03A 3ln1D-1bh6A:
undetectable		 3ln1D-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 8 ILE A 107
LEU A 126
ILE A 122
GLY A  65
 1BH  A 300 ( 4.9A)
1BH  A 300 (-4.0A)
None
None
 0.79A 4hb8A-1bh6A:
undetectable		 4hb8A-1bh6A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 6 SER A 221
ALA A 152
HIS A  64
LEU A 126
 1BH  A 300 ( 1.7A)
1BH  A 300 ( 3.7A)
1BH  A 300 ( 3.0A)
1BH  A 300 (-4.0A)
 1.28A 5dzkB-1bh6A:
2.7
5dzkP-1bh6A:
undetectable		 5dzkB-1bh6A:
22.54
5dzkP-1bh6A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 6 ILE A  93
GLY A  63
ASN A  62
ILE A  30
 None
None
1BH  A 300 ( 4.6A)
None
 0.89A 5j4nB-1bh6A:
0.0		 5j4nB-1bh6A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.01A 5kirA-1bh6A:
undetectable		 5kirA-1bh6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.05A 5kirB-1bh6A:
0.0		 5kirB-1bh6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 GLY A 154
SER A 190
ARG A 186
GLY A 157
 1BH  A 300 (-3.5A)
None
None
None
 1.13A 5kprA-1bh6A:
undetectable		 5kprA-1bh6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 ALA A 134
SER A 132
GLY A 131
TYR A 171
 None
None
1BH  A 300 ( 4.8A)
None
 1.18A 5yodB-1bh6A:
0.0		 5yodB-1bh6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 ALA A 134
SER A 132
GLY A 131
TYR A 171
 None
None
1BH  A 300 ( 4.8A)
None
 1.21A 5yodD-1bh6A:
undetectable		 5yodD-1bh6A:
21.23