SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1B0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A99_D_MIYD393_1 (TETX2 PROTEIN)	2xde	GAG POLYPROTEIN (Human immunodeficiency virus 1)	4 / 5	ILE A 73 ILE A 129 TYR A 130 GLU A 128	1B0 A1148 ( 4.1A) None None None	1.12A	4a99D-2xdeA: undetectable	4a99D-2xdeA: 16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_B_FK5B201_1 (FK506-BINDING PROTEIN 1)	2xde	GAG POLYPROTEIN (Human immunodeficiency virus 1)	5 / 11	PHE A 32 VAL A 59 TRP A 23 ILE A 73 PHE A 40	None None None 1B0 A1148 ( 4.1A) None	1.31A	5hw8B-2xdeA: undetectable	5hw8B-2xdeA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_D_FK5D201_1 (FK506-BINDING PROTEIN 1)	2xde	GAG POLYPROTEIN (Human immunodeficiency virus 1)	5 / 11	PHE A 32 VAL A 59 TRP A 23 ILE A 73 PHE A 40	None None None 1B0 A1148 ( 4.1A) None	1.21A	5hw8D-2xdeA: undetectable	5hw8D-2xdeA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZWR_A_9KLA402_0 (EST-Y29)	2xde	GAG POLYPROTEIN (Human immunodeficiency virus 1)	5 / 12	PHE A 40 ILE A 134 LEU A 56 GLY A 46 ALA A 47	None None 1B0 A1148 (-4.1A) None None	1.24A	5zwrA-2xdeA: undetectable	5zwrA-2xdeA: 15.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A99_D_MIYD393_1","TETX2 PROTEIN","2xde","GAG POLYPROTEIN","Human immunodeficiency virus 1",4,"ILE A  73;ILE A 129;TYR A 130;GLU A 128","1B0 A1148 ( 4.1A);None;None;None","1.12A","4a99D-2xdeA:undetectable",null],["5HW8_B_FK5B201_1","FK506-BINDING PROTEIN 1","2xde","GAG POLYPROTEIN","Human immunodeficiency virus 1",5,"PHE A  32;VAL A  59;TRP A  23;ILE A  73;PHE A  40","None;None;None;1B0 A1148 ( 4.1A);None","1.31A","5hw8B-2xdeA:undetectable","4a99D-2xdeA:16.13"],["5HW8_D_FK5D201_1","FK506-BINDING PROTEIN 1","2xde","GAG POLYPROTEIN","Human immunodeficiency virus 1",5,"PHE A  32;VAL A  59;TRP A  23;ILE A  73;PHE A  40","None;None;None;1B0 A1148 ( 4.1A);None","1.21A","5hw8D-2xdeA:undetectable","5hw8B-2xdeA:20.00"],["5ZWR_A_9KLA402_0","EST-Y29","2xde","GAG POLYPROTEIN","Human immunodeficiency virus 1",5,"PHE A  40;ILE A 134;LEU A  56;GLY A  46;ALA A  47","None;None;1B0 A1148 (-4.1A);None;None","1.24A","5zwrA-2xdeA:undetectable","5hw8D-2xdeA:20.00"]]