SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '19S'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FMO_E_ADNE351_1 (CAMP-DEPENDENT PROTEIN KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 VAL A 884 ASN A 954 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.68A	1fmoE-4hviA: 24.4	1fmoE-4hviA: 23.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IEP_A_STIA201_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.55A	1iepA-4hviA: 29.9	1iepA-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 LEU A 900 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.88A	1m17A-4hviA: 28.2	1m17A-4hviA: 34.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MUO_A_ADNA1_1 (AURORA-RELATED KINASE 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 GLY A 829 VAL A 836 ALA A 853 TYR A 904 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A)	0.65A	1muoA-4hviA: 18.3	1muoA-4hviA: 26.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OPJ_A_STIA3_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.58A	1opjA-4hviA: 29.5	1opjA-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OPJ_B_STIB4_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 GLU A 871 VAL A 884 GLY A 908 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 ( 3.8A) 19S  A1201 ( 4.1A)	0.71A	1opjB-4hviA: 24.1	1opjB-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1T46_A_STIA3_1 (HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 LEU A 875 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.60A	1t46A-4hviA: 23.7	1t46A-4hviA: 33.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWH_A_BAXA1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 12	ALA A 853 GLU A 871 LEU A 875 LEU A 940 HIS A 947	19S  A1201 (-3.3A) None None None None	0.66A	1uwhA-4hviA: 27.2	1uwhA-4hviA: 29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 LYS A 855 GLU A 871 LEU A 875 LEU A 940 HIS A 947	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None None	0.64A	1uwhB-4hviA: 27.0	1uwhB-4hviA: 29.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XBB_A_STIA1_1 (TYROSINE-PROTEIN KINASE SYK)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 VAL A 836 ALA A 853 MET A 902 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.55A	1xbbA-4hviA: 34.4	1xbbA-4hviA: 35.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XKK_A_FMMA91_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLY A 908 CYH A 909 ASP A 912 LEU A 956 PHE A 968	19S  A1201 (-3.3A) 19S  A1201 ( 3.8A) None None 19S  A1201 (-4.5A) None	0.85A	1xkkA-4hviA: 30.4	1xkkA-4hviA: 33.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XKK_A_FMMA91_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	GLY A 908 CYH A 909 ASP A 912 LEU A 956 ASP A 967 PHE A 968	19S  A1201 ( 3.8A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) None	0.94A	1xkkA-4hviA: 30.4	1xkkA-4hviA: 33.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 LYS A 855 VAL A 884 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-4.4A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.60A	2eufB-4hviA: 26.3	2eufB-4hviA: 25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EVA_A_ADNA498_1 (TAK1 KINASE - TAB1 CHIMERA FUSION PROTEIN)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 11	GLY A 829 VAL A 836 ALA A 853 MET A 902 TYR A 904 LEU A 956	19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A)	0.32A	2evaA-4hviA: 27.0	2evaA-4hviA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_A_MIXA539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 ASP A 949 ASN A 954 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 ( 4.1A)	0.54A	2fumA-4hviA: 26.6	2fumA-4hviA: 26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_B_MIXB1539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 MET A 902 TYR A 904 ASN A 954 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) None 19S  A1201 ( 4.1A)	0.52A	2fumB-4hviA: 26.6	2fumB-4hviA: 26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_C_MIXC2539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 MET A 902 TYR A 904 ASN A 954	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) None	0.45A	2fumC-4hviA: 18.0	2fumC-4hviA: 26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_D_MIXD3539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 GLY A 829 GLY A 831 VAL A 836 ALA A 853 MET A 902 ASN A 954	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) None	0.56A	2fumD-4hviA: 24.8	2fumD-4hviA: 26.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2GQG_B_1N1B502_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.67A	2gqgB-4hviA: 33.7	2gqgB-4hviA: 35.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2HYY_A_STIA600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.69A	2hyyA-4hviA: 25.3	2hyyA-4hviA: 34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2HYY_B_STIB600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.64A	2hyyB-4hviA: 30.4	2hyyB-4hviA: 34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2HYY_C_STIC600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 ALA A 853 GLU A 871 VAL A 884 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.55A	2hyyC-4hviA: 30.3	2hyyC-4hviA: 34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ITO_A_IREA2020_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 LEU A 900 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.91A	2itoA-4hviA: 31.9	2itoA-4hviA: 34.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ITY_A_IREA2020_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 LYS A 855 GLU A 871 LEU A 900 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	1.01A	2ityA-4hviA: 31.8	2ityA-4hviA: 34.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4L_A_TPVA403_1 (PROTEASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 12	LEU A 910 ASP A 949 ASP A 967 VAL A 963 ILE A 955	None None 19S  A1201 ( 4.1A) None None	1.23A	2o4lA-4hviA: undetectable	2o4lA-4hviA: 15.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OIQ_A_STIA1001_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 GLU A 871 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.62A	2oiqA-4hviA: 29.6	2oiqA-4hviA: 33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2PL0_A_STIA200_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 GLU A 871 VAL A 884 TYR A 904 ALA A 966 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.91A	2pl0A-4hviA: 24.1	2pl0A-4hviA: 35.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2PL0_A_STIA200_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 GLU A 871 VAL A 884 TYR A 904 LEU A 956 ALA A 966	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.73A	2pl0A-4hviA: 24.1	2pl0A-4hviA: 35.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	GLY A 829 ALA A 853 TYR A 904 GLY A 908 ALA A 966 ASP A 967	19S  A1201 (-3.7A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.64A	2wgjA-4hviA: 29.2	2wgjA-4hviA: 33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ZVA_A_1N1A513_1 (TYROSINE-PROTEIN KINASE LYN)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 VAL A 884 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.86A	2zvaA-4hviA: 31.3	2zvaA-4hviA: 32.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 GLY A 829 ALA A 853 LYS A 855 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.74A	3c7qA-4hviA: 23.8	3c7qA-4hviA: 33.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_A_NILA600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLU A 871 GLY A 908 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.54A	3cs9A-4hviA: 30.4	3cs9A-4hviA: 35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_B_NILB600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 9	LEU A 828 VAL A 836 LYS A 855 VAL A 884 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.5A)	0.48A	3cs9B-4hviA: 30.1	3cs9B-4hviA: 35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_D_NILD600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 6	LEU A 828 VAL A 836 LYS A 855 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) 19S  A1201 (-4.5A)	0.66A	3cs9D-4hviA: 28.7	3cs9D-4hviA: 35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3EYG_A_MI1A1_1 (TYROSINE-PROTEIN KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	10 / 12	LEU A 828 GLY A 829 GLY A 831 GLY A 834 VAL A 836 ALA A 853 LYS A 855 MET A 902 ASN A 954 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 ( 4.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 (-3.6A) None 19S  A1201 (-4.5A)	0.59A	3eygA-4hviA: 39.2	3eygA-4hviA: 48.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3FUP_A_MI1A1_1 (TYROSINE-PROTEIN KINASE JAK2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	10 / 12	LEU A 828 GLY A 829 GLY A 831 GLY A 834 VAL A 836 ALA A 853 LYS A 855 MET A 902 TYR A 904 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 ( 4.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A)	0.64A	3fupA-4hviA: 40.3	3fupA-4hviA: 61.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3FUP_B_MI1B1_1 (TYROSINE-PROTEIN KINASE JAK2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	11 / 12	LEU A 828 GLY A 829 GLY A 831 VAL A 836 ALA A 853 LYS A 855 VAL A 884 MET A 902 TYR A 904 LEU A 905 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 (-4.4A) 19S  A1201 (-4.5A)	0.32A	3fupB-4hviA: 32.3	3fupB-4hviA: 61.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3FUP_B_MI1B1_1 (TYROSINE-PROTEIN KINASE JAK2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 GLY A 834 VAL A 836 ALA A 853 VAL A 884 MET A 902 TYR A 904 LEU A 905	19S  A1201 (-3.9A) 19S  A1201 ( 4.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 (-4.4A)	0.99A	3fupB-4hviA: 32.3	3fupB-4hviA: 61.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G0E_A_B49A9000_1 (MAST/STEM CELL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 11	LEU A 828 VAL A 836 ALA A 853 VAL A 884 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.49A	3g0eA-4hviA: 27.5	3g0eA-4hviA: 31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G0F_A_B49A9001_1 (MAST/STEM CELL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 11	LEU A 828 VAL A 836 ALA A 853 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.49A	3g0fA-4hviA: 29.2	3g0fA-4hviA: 31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G0F_B_B49B9001_1 (MAST/STEM CELL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 10	LEU A 828 VAL A 836 ALA A 853 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.39A	3g0fB-4hviA: 29.3	3g0fB-4hviA: 31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G5D_A_1N1A1_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 TYR A 904 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.70A	3g5dA-4hviA: 25.8	3g5dA-4hviA: 33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G5D_A_1N1A1_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.61A	3g5dA-4hviA: 25.8	3g5dA-4hviA: 33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G5D_B_1N1B1_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	10 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.83A	3g5dB-4hviA: 25.7	3g5dB-4hviA: 33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GVU_A_STIA1001_1 (TYROSINE-PROTEIN KINASE ABL2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.55A	3gvuA-4hviA: 25.2	3gvuA-4hviA: 35.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3IK3_A_0LIA1_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLU A 871 VAL A 884 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.69A	3ik3A-4hviA: 29.8	3ik3A-4hviA: 35.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3IK3_B_0LIB2_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 12	ALA A 853 GLU A 871 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.48A	3ik3B-4hviA: 24.7	3ik3B-4hviA: 35.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3K5V_A_STIA2_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.65A	3k5vA-4hviA: 29.1	3k5vA-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3K5V_B_STIB2_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.64A	3k5vB-4hviA: 24.1	3k5vB-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LXK_A_MI1A1125_1 (TYROSINE-PROTEIN KINASE JAK3)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	11 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 LYS A 855 VAL A 884 MET A 902 TYR A 904 CYH A 909 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.66A	3lxkA-4hviA: 43.1	3lxkA-4hviA: 99.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LXK_A_MI1A1125_1 (TYROSINE-PROTEIN KINASE JAK3)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 GLY A 829 VAL A 884 TYR A 904 CYH A 909 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) None 19S  A1201 (-4.7A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.89A	3lxkA-4hviA: 43.1	3lxkA-4hviA: 99.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LXN_A_MI1A1_1 (NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 GLY A 829 GLY A 831 VAL A 836 ALA A 853 LYS A 855 TYR A 904	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A)	0.55A	3lxnA-4hviA: 31.0	3lxnA-4hviA: 45.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LXN_A_MI1A1_1 (NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 LYS A 855 TYR A 904 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A)	0.21A	3lxnA-4hviA: 31.0	3lxnA-4hviA: 45.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MS9_B_STIB1_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.65A	3ms9B-4hviA: 29.7	3ms9B-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_B_STIB1_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.55A	3mssB-4hviA: 25.2	3mssB-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_B_STIB1_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.65A	3mssB-4hviA: 25.2	3mssB-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_C_STIC1_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.69A	3mssC-4hviA: 29.7	3mssC-4hviA: 35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_D_STID1_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 ALA A 853 GLU A 871 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.55A	3mssD-4hviA: 29.7	3mssD-4hviA: 35.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OCT_A_1N1A663_1 (TYROSINE-PROTEIN KINASE BTK)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 VAL A 884 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.63A	3octA-4hviA: 29.5	3octA-4hviA: 29.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OEZ_A_STIA601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.3A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.48A	3oezA-4hviA: 24.4	3oezA-4hviA: 33.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_B_1N1B1000_1 (P38A)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	GLY A 829 VAL A 836 ALA A 853 LYS A 855 LEU A 875 GLY A 908	19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A)	0.86A	3ohtB-4hviA: 16.8	3ohtB-4hviA: 23.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OXZ_A_0LIA1_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLU A 871 VAL A 884 GLY A 908 HIS A 947 ALA A 966	19S  A1201 (-3.3A) None None 19S  A1201 ( 3.8A) None 19S  A1201 ( 4.1A)	0.51A	3oxzA-4hviA: 25.3	3oxzA-4hviA: 34.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PYY_B_STIB4_1 (V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.54A	3pyyB-4hviA: 29.9	3pyyB-4hviA: 34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QLG_A_1N1A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	10 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.86A	3qlgA-4hviA: 30.0	3qlgA-4hviA: 33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QLG_B_1N1B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.80A	3qlgB-4hviA: 30.9	3qlgB-4hviA: 33.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGF_A_BAXA465_1 (CYCLIN-DEPENDENT KINASE 8)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	VAL A 836 ALA A 853 GLU A 871 LEU A 875 TYR A 904 LEU A 940 HIS A 947 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.7A) None None 19S  A1201 ( 4.1A)	0.97A	3rgfA-4hviA: 16.1	3rgfA-4hviA: 24.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SXR_A_1N1A1_1 (CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 VAL A 884 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.44A	3sxrA-4hviA: 30.9	3sxrA-4hviA: 32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SXR_B_1N1B2_1 (CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 VAL A 884 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.44A	3sxrB-4hviA: 30.6	3sxrB-4hviA: 32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UE4_A_DB8A601_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.79A	3ue4A-4hviA: 34.0	3ue4A-4hviA: 35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UE4_B_DB8B601_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.72A	3ue4B-4hviA: 33.6	3ue4B-4hviA: 35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UG2_A_IREA1_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 ALA A 853 LYS A 855 LEU A 900 MET A 902 GLY A 908 ASP A 912 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-3.6A) 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A)	0.90A	3ug2A-4hviA: 33.6	3ug2A-4hviA: 34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UG2_A_IREA1_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 LEU A 900 GLY A 908 ASP A 912 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A)	0.90A	3ug2A-4hviA: 33.6	3ug2A-4hviA: 34.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V5W_A_8PRA701_1 (G-PROTEIN COUPLED RECEPTOR KINASE 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	GLY A 831 GLY A 834 VAL A 836 ALA A 853 LYS A 855 VAL A 884	19S  A1201 ( 4.3A) 19S  A1201 ( 4.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None	0.77A	3v5wA-4hviA: 7.4	3v5wA-4hviA: 18.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WZD_A_LEVA1201_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 LEU A 875 GLY A 908	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 ( 3.8A)	0.59A	3wzdA-4hviA: 29.7	3wzdA-4hviA: 35.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WZD_A_LEVA1201_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 5	LYS A 855 ILE A 874 LEU A 956 ASP A 967	19S  A1201 (-3.5A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	1.12A	3wzdA-4hviA: 29.7	3wzdA-4hviA: 35.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WZD_A_LEVA1201_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 5	LYS A 855 ILE A 874 VAL A 884 LEU A 956	19S  A1201 (-3.5A) None None 19S  A1201 (-4.5A)	0.58A	3wzdA-4hviA: 29.7	3wzdA-4hviA: 35.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WZE_A_BAXA1201_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 LEU A 875 GLY A 908 LEU A 940 HIS A 947	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) None None	0.65A	3wzeA-4hviA: 30.5	3wzeA-4hviA: 35.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZOS_A_0LIA1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 LEU A 940 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.53A	3zosA-4hviA: 22.8	3zosA-4hviA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZOS_A_0LIA1000_2 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 9	ILE A 874 LEU A 878 ILE A 883 TYR A 904 ILE A 965	None None None 19S  A1201 (-4.7A) None	0.62A	3zosA-4hviA: 22.8	3zosA-4hviA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 LYS A 855 GLU A 871 HIS A 947 ARG A 948 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	1.29A	3zosB-4hviA: 29.2	3zosB-4hviA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 GLU A 871 LEU A 940 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.54A	3zosB-4hviA: 29.2	3zosB-4hviA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZOS_B_0LIB1000_2 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 ILE A 874 LEU A 878 ILE A 883 TYR A 904 ILE A 965	19S  A1201 (-3.9A) None None None 19S  A1201 (-4.7A) None	0.66A	3zosB-4hviA: 29.2	3zosB-4hviA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.45A	4ag8A-4hviA: 30.4	4ag8A-4hviA: 34.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.44A	4agcA-4hviA: 29.8	4agcA-4hviA: 31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGD_A_B49A2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 11	LEU A 828 ALA A 853 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.42A	4agdA-4hviA: 29.2	4agdA-4hviA: 31.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 ALA A 853 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.68A	4anqA-4hviA: 29.8	4anqA-4hviA: 28.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ANS_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	ALA A 853 MET A 902 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.54A	4ansA-4hviA: 29.7	4ansA-4hviA: 28.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ANS_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 9	LEU A 828 VAL A 836 ALA A 853 MET A 902 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.80A	4ansA-4hviA: 29.7	4ansA-4hviA: 28.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4ASD_A_BAXA1500_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 LEU A 875 GLY A 908 LEU A 940 HIS A 947	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) None None	0.78A	4asdA-4hviA: 30.0	4asdA-4hviA: 31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BKJ_A_STIA1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 ALA A 853 GLU A 871 ILE A 874 TYR A 904 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.87A	4bkjA-4hviA: 23.3	4bkjA-4hviA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 GLU A 871 ILE A 874 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.77A	4bkjB-4hviA: 23.1	4bkjB-4hviA: 33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 LYS A 855 GLU A 871 LEU A 875 HIS A 947 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.99A	4c8bA-4hviA: 25.7	4c8bA-4hviA: 29.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_A_0LIA1000_2 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 5	VAL A 836 ILE A 883 TYR A 904 ILE A 965	19S  A1201 (-4.4A) None 19S  A1201 (-4.7A) None	0.60A	4c8bA-4hviA: 25.7	4c8bA-4hviA: 29.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 LYS A 855 GLU A 871 LEU A 875 ILE A 883 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.53A	4c8bB-4hviA: 18.7	4c8bB-4hviA: 29.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LYS A 855 GLU A 871 LEU A 875 ILE A 883 HIS A 947 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.5A) None None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.97A	4c8bB-4hviA: 18.7	4c8bB-4hviA: 29.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4CKJ_A_ADNA2014_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 10	LEU A 828 GLY A 829 GLY A 831 VAL A 836 ALA A 853 TYR A 904 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A)	0.39A	4ckjA-4hviA: 35.2	4ckjA-4hviA: 34.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4CSV_A_STIA1265_1 (SRC-ABL TYROSINE KINASE ANCESTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	VAL A 836 ALA A 853 GLU A 871 ILE A 874 VAL A 884 TYR A 904 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None None 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.71A	4csvA-4hviA: 29.9	4csvA-4hviA: 37.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4I22_A_IREA9001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 GLY A 829 ALA A 853 LYS A 855 LEU A 900 MET A 902 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-3.6A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.85A	4i22A-4hviA: 29.9	4i22A-4hviA: 34.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4I22_A_IREA9001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 GLY A 829 VAL A 836 ALA A 853 LYS A 855 LEU A 900 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.71A	4i22A-4hviA: 29.9	4i22A-4hviA: 34.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KS8_A_B49A701_1 (SERINE/THREONINE-PRO TEIN KINASE PAK 6)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 10	ALA A 853 VAL A 884 MET A 902 LEU A 905 GLY A 908 LEU A 956	19S  A1201 (-3.3A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.4A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.37A	4ks8A-4hviA: 20.1	4ks8A-4hviA: 25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.79A	4mkcA-4hviA: 30.1	4mkcA-4hviA: 27.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXO_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 VAL A 884 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.84A	4mxoB-4hviA: 25.7	4mxoB-4hviA: 33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXX_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.85A	4mxxA-4hviA: 25.6	4mxxA-4hviA: 33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXY_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 GLU A 871 VAL A 884 MET A 902 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.3A) None None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.87A	4mxyA-4hviA: 24.8	4mxyA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXY_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 LYS A 855 VAL A 884 MET A 902 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.83A	4mxyA-4hviA: 24.8	4mxyA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXY_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	1.11A	4mxyA-4hviA: 24.8	4mxyA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXY_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.97A	4mxyA-4hviA: 24.8	4mxyA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXY_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 VAL A 884 MET A 902 TYR A 904 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.3A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.72A	4mxyB-4hviA: 24.9	4mxyB-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXY_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 ALA A 853 LYS A 855 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.87A	4mxyB-4hviA: 24.9	4mxyB-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXY_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 TYR A 904 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.91A	4mxyB-4hviA: 24.9	4mxyB-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXZ_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 GLU A 871 VAL A 884 MET A 902 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.3A) None None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.87A	4mxzA-4hviA: 24.8	4mxzA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXZ_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 LYS A 855 VAL A 884 MET A 902 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.83A	4mxzA-4hviA: 24.8	4mxzA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXZ_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	1.11A	4mxzA-4hviA: 24.8	4mxzA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXZ_A_DB8A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.97A	4mxzA-4hviA: 24.8	4mxzA-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXZ_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	ALA A 853 VAL A 884 MET A 902 TYR A 904 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.3A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.72A	4mxzB-4hviA: 24.9	4mxzB-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXZ_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 ALA A 853 LYS A 855 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.87A	4mxzB-4hviA: 24.9	4mxzB-4hviA: 34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXZ_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 TYR A 904 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.91A	4mxzB-4hviA: 24.9	4mxzB-4hviA: 34.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O0W_A_ADNA501_1 (AURORA KINASE A)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 6	LEU A 828 GLY A 829 VAL A 836 ALA A 853 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.5A)	0.39A	4o0wA-4hviA: 20.2	4o0wA-4hviA: 26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_E_ADNE401_1 (CYCLIN-DEPENDENT KINASE 9)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 7	GLY A 829 ALA A 853 ASN A 954 LEU A 956 ASP A 967	19S  A1201 (-3.7A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.63A	4ogrE-4hviA: 25.2	4ogrE-4hviA: 26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTI_A_MI1A1001_1 (SERINE/THREONINE-PRO TEIN KINASE N1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 GLY A 829 GLY A 831 GLY A 834 VAL A 836 ALA A 853 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 ( 4.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.55A	4otiA-4hviA: 19.7	4otiA-4hviA: 29.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTI_A_MI1A1001_1 (SERINE/THREONINE-PRO TEIN KINASE N1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 GLY A 831 VAL A 836 ALA A 853 LYS A 855 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 ( 4.3A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.70A	4otiA-4hviA: 19.7	4otiA-4hviA: 29.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OTW_A_DB8A1101_1 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 LYS A 855 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.77A	4otwA-4hviA: 24.7	4otwA-4hviA: 33.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OTW_A_DB8A1101_1 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.83A	4otwA-4hviA: 24.7	4otwA-4hviA: 33.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMN_A_DB8A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 GLU A 871 MET A 902 TYR A 904 ALA A 966 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.95A	4qmnA-4hviA: 27.9	4qmnA-4hviA: 27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMN_A_DB8A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 GLU A 871 TYR A 904 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.75A	4qmnA-4hviA: 27.9	4qmnA-4hviA: 27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMS_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 11	ALA A 853 GLU A 871 MET A 902 TYR A 904 LEU A 905 ASP A 967	19S  A1201 (-3.3A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 (-4.4A) 19S  A1201 ( 4.1A)	0.78A	4qmsA-4hviA: 21.3	4qmsA-4hviA: 27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMS_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 11	ALA A 853 GLU A 871 TYR A 904 LEU A 905 LEU A 956 ASP A 967	19S  A1201 (-3.3A) None 19S  A1201 (-4.7A) 19S  A1201 (-4.4A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.57A	4qmsA-4hviA: 21.3	4qmsA-4hviA: 27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMS_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 11	ALA A 853 LYS A 855 TYR A 904 LEU A 905 LEU A 956 ASP A 967	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.4A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.75A	4qmsA-4hviA: 21.3	4qmsA-4hviA: 27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMZ_A_B49A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	GLY A 829 VAL A 836 ALA A 853 MET A 902 TYR A 904 LEU A 905 LEU A 956	19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 (-4.4A) 19S  A1201 (-4.5A)	0.52A	4qmzA-4hviA: 21.1	4qmzA-4hviA: 27.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4QRC_A_0LIA802_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLU A 871 LEU A 940 CYH A 945 ARG A 948 ALA A 966	19S  A1201 (-3.3A) None None None None 19S  A1201 ( 4.1A)	0.98A	4qrcA-4hviA: 30.6	4qrcA-4hviA: 33.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R7I_A_STIA1001_1 (MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 LYS A 855 GLU A 871 CYH A 945 LEU A 956	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.5A)	0.55A	4r7iA-4hviA: 29.8	4r7iA-4hviA: 28.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLY A 908 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.54A	4twpA-4hviA: 34.0	4twpA-4hviA: 35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLY A 908 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.56A	4twpB-4hviA: 33.7	4twpB-4hviA: 35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TYJ_A_0LIA801_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLU A 871 CYH A 945 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.58A	4tyjA-4hviA: 30.0	4tyjA-4hviA: 33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TYJ_A_0LIA801_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 6	LEU A 828 VAL A 836 LYS A 855 ILE A 883 ILE A 965	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) None None	0.56A	4tyjA-4hviA: 30.0	4tyjA-4hviA: 33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U0I_A_0LIA1001_1 (MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 10	LEU A 828 VAL A 836 GLU A 871 LEU A 878 ILE A 883 VAL A 884 TYR A 904 ILE A 965	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) None None None None 19S  A1201 (-4.7A) None	0.64A	4u0iA-4hviA: 30.0	4u0iA-4hviA: 32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U0I_A_0LIA1001_2 (MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	ALA A 853 LYS A 855 LEU A 875 GLY A 908 CYH A 945 HIS A 947 LEU A 956	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) None None 19S  A1201 (-4.5A)	0.66A	4u0iA-4hviA: 30.0	4u0iA-4hviA: 32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U5J_A_RXTA601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	10 / 11	LEU A 828 GLY A 831 VAL A 836 ALA A 853 TYR A 904 GLY A 908 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 ( 4.3A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.73A	4u5jA-4hviA: 26.1	4u5jA-4hviA: 33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U5J_A_RXTA601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 11	LEU A 828 GLY A 834 VAL A 836 ALA A 853 TYR A 904 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 ( 4.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	1.25A	4u5jA-4hviA: 26.1	4u5jA-4hviA: 33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U5J_B_RXTB601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 VAL A 836 ALA A 853 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.50A	4u5jB-4hviA: 26.3	4u5jB-4hviA: 33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 ALA A 853 GLU A 871 LEU A 940 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.63A	4uxqA-4hviA: 30.4	4uxqA-4hviA: 34.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LEU A 940 CYH A 945 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.53A	4uxqA-4hviA: 30.4	4uxqA-4hviA: 34.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_A_0LIA1776_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 12	ALA A 853 GLU A 871 LEU A 940 HIS A 947 ALA A 966	19S  A1201 (-3.3A) None None None 19S  A1201 ( 4.1A)	0.64A	4v01A-4hviA: 29.5	4v01A-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_A_0LIA1776_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 VAL A 836 LYS A 855 TYR A 904 LEU A 956 ILE A 883	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) None	1.13A	4v01A-4hviA: 29.5	4v01A-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_A_0LIA1776_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 VAL A 836 LYS A 855 TYR A 904 LEU A 956 ILE A 965	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) None	0.63A	4v01A-4hviA: 29.5	4v01A-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_B_0LIB1770_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLU A 871 LEU A 940 CYH A 945 HIS A 947 ALA A 966	19S  A1201 (-3.3A) None None None None 19S  A1201 ( 4.1A)	0.55A	4v01B-4hviA: 29.9	4v01B-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_B_0LIB1770_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 VAL A 836 LYS A 855 TYR A 904 LEU A 956 ILE A 965	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) None	0.58A	4v01B-4hviA: 29.9	4v01B-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V04_A_0LIA1772_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 ALA A 853 GLU A 871 LEU A 940 CYH A 945 HIS A 947 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None None None None 19S  A1201 ( 4.1A)	0.73A	4v04A-4hviA: 29.2	4v04A-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V04_A_0LIA1772_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 8	LYS A 855 TYR A 904 LEU A 956 ILE A 965	19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) None	0.79A	4v04A-4hviA: 29.2	4v04A-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V04_B_0LIB1771_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 10	LEU A 828 VAL A 836 LYS A 855 TYR A 904 LEU A 956 ILE A 883	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) None	0.98A	4v04B-4hviA: 29.8	4v04B-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V04_B_0LIB1771_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 10	LEU A 828 VAL A 836 LYS A 855 TYR A 904 LEU A 956 ILE A 965	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A) None	0.62A	4v04B-4hviA: 29.8	4v04B-4hviA: 35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V04_B_0LIB1771_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 GLU A 871 LEU A 940 CYH A 945 HIS A 947 ALA A 966	19S  A1201 (-3.3A) None None None None 19S  A1201 ( 4.1A)	0.65A	4v04B-4hviA: 29.8	4v04B-4hviA: 35.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WBO_B_ANWB601_0 (RHODOPSIN KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 8	LEU A 828 ALA A 853 MET A 902 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 (-4.5A)	0.47A	4wboB-4hviA: 20.1	4wboB-4hviA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WBO_C_ANWC601_0 (RHODOPSIN KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 6	LEU A 828 ALA A 853 MET A 902 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.6A) 19S  A1201 (-4.5A)	0.48A	4wboC-4hviA: 23.5	4wboC-4hviA: 20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WKQ_A_IREA1101_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 LEU A 900 GLY A 908 ASP A 912 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A)	0.96A	4wkqA-4hviA: 34.2	4wkqA-4hviA: 34.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_2 (ESTROGEN RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 5	LEU A 956 GLU A 958 LEU A 875 HIS A 947	19S  A1201 (-4.5A) None None None	1.25A	4xi3B-4hviA: undetectable	4xi3B-4hviA: 22.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XLI_A_1N1A601_1 (NON-SPECIFIC PROTEIN-TYROSINE KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.80A	4xliA-4hviA: 34.4	4xliA-4hviA: 36.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XLI_B_1N1B600_1 (NON-SPECIFIC PROTEIN-TYROSINE KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 VAL A 884 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.68A	4xliB-4hviA: 34.2	4xliB-4hviA: 36.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AAA_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 9	LEU A 828 VAL A 836 ALA A 853 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.79A	5aaaA-4hviA: 23.4	5aaaA-4hviA: 29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AAB_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 10	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.85A	5aabA-4hviA: 23.4	5aabA-4hviA: 29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AJQ_A_DB8A800_1 (SERINE/THREONINE-PRO TEIN KINASE 10)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LYS A 855 GLY A 908 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	1.21A	5ajqA-4hviA: 22.7	5ajqA-4hviA: 29.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5BVW_A_1N1A1009_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 TYR A 904 GLY A 908 LEU A 956 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.44A	5bvwA-4hviA: 29.7	5bvwA-4hviA: 33.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HI2_A_BAXA801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	ALA A 853 LYS A 855 GLU A 871 LEU A 875 LEU A 940 HIS A 947	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None None	0.69A	5hi2A-4hviA: 26.9	5hi2A-4hviA: 28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZJ_F_AZ1F2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAR-DAR-DAR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 7	GLY A 829 GLY A 831 GLY A 834 VAL A 836	19S  A1201 (-3.7A) 19S  A1201 ( 4.3A) 19S  A1201 ( 4.9A) 19S  A1201 (-4.4A)	0.27A	5izjB-4hviA: 23.6	5izjB-4hviA: 24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	GLY A 829 VAL A 836 ALA A 853 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.56A	5l2iA-4hviA: 22.9	5l2iA-4hviA: 26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENT KINASE 6)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	GLY A 829 VAL A 836 ALA A 853 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.83A	5l2tA-4hviA: 23.1	5l2tA-4hviA: 26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LVN_A_ADNA402_1 (3-PHOSPHOINOSITIDE-D EPENDENT PROTEIN KINASE 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 11	LEU A 828 GLY A 829 VAL A 836 ALA A 853 VAL A 884 TYR A 904 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.7A) 19S  A1201 (-4.5A)	0.53A	5lvnA-4hviA: 13.9	5lvnA-4hviA: 24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MO4_A_NILA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 10	LEU A 828 VAL A 836 LYS A 855 GLU A 871 GLY A 908	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A)	0.53A	5mo4A-4hviA: 23.9	5mo4A-4hviA: 26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MO4_A_NILA601_2 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 12	ALA A 853 VAL A 884 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.63A	5mo4A-4hviA: 23.9	5mo4A-4hviA: 26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N3H_A_NCAA401_0 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 10	LEU A 828 VAL A 836 ALA A 853 VAL A 884 MET A 902 TYR A 904 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-3.6A) 19S  A1201 (-4.7A) 19S  A1201 (-4.5A)	0.53A	5n3hA-4hviA: 24.8	5n3hA-4hviA: 24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OWR_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 10)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	4 / 8	ALA A 853 GLU A 871 LEU A 956 ASP A 967	19S  A1201 (-3.3A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.46A	5owrA-4hviA: 14.9	5owrA-4hviA: 28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 838 ALA A 853 GLU A 871 VAL A 884 GLY A 908 LEU A 956	None 19S  A1201 (-3.3A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.54A	5te0A-4hviA: 25.2	5te0A-4hviA: 25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCV_A_1N1A404_1 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 LEU A 900 GLY A 908	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A)	1.05A	5vcvA-4hviA: 24.3	5vcvA-4hviA: 24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCV_A_1N1A404_1 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 VAL A 884 GLY A 908	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A)	1.03A	5vcvA-4hviA: 24.3	5vcvA-4hviA: 24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCY_A_DB8A401_1 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 LEU A 900	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None	0.90A	5vcyA-4hviA: 24.4	5vcyA-4hviA: 24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W5V_A_ANWA701_0 (SERINE/THREONINE-PRO TEIN KINASE TBK1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	5 / 9	LEU A 828 ALA A 853 VAL A 884 MET A 902 GLY A 908	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) None 19S  A1201 (-3.6A) 19S  A1201 ( 3.8A)	0.69A	5w5vA-4hviA: 11.8	5w5vA-4hviA: 18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.70A	5y7zA-4hviA: 24.7	5y7zA-4hviA: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.70A	5y7zA-4hviA: 24.7	5y7zA-4hviA: 23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_B_IREB401_0 (CYCLIN-G-ASSOCIATED KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.69A	5y7zB-4hviA: 24.8	5y7zB-4hviA: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_B_IREB401_0 (CYCLIN-G-ASSOCIATED KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 LEU A 900 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.64A	5y7zB-4hviA: 24.8	5y7zB-4hviA: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y80_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.67A	5y80A-4hviA: 24.2	5y80A-4hviA: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YU9_C_1E8C1101_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 LEU A 900 GLY A 908 CYH A 909 ASP A 912	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 ( 3.8A) None None	0.91A	5yu9C-4hviA: 29.4	5yu9C-4hviA: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YU9_D_1E8D1101_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	VAL A 836 ALA A 853 GLY A 908 CYH A 909 ASP A 912 LEU A 956	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 ( 3.8A) None None 19S  A1201 (-4.5A)	0.63A	5yu9D-4hviA: 29.8	5yu9D-4hviA: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZV2_A_LEVA801_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 GLU A 871 TYR A 904 GLY A 908 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 ( 4.1A)	0.57A	5zv2A-4hviA: 29.7	5zv2A-4hviA: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZV2_B_LEVB801_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 GLY A 908 ALA A 966	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 ( 4.1A)	0.50A	5zv2B-4hviA: 24.1	5zv2B-4hviA: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZV2_B_LEVB801_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	3 / 3	TYR A 904 LEU A 956 ASP A 967	19S  A1201 (-4.7A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.86A	5zv2B-4hviA: 24.1	5zv2B-4hviA: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BSD_A_1N1A901_0 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 ALA A 853 LYS A 855 GLU A 871 TYR A 904 GLY A 908 LEU A 956	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 (-4.7A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.31A	6bsdA-4hviA: 29.1	6bsdA-4hviA: 14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_A_STIA604_0 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.66A	6hd4A-4hviA: 29.0	6hd4A-4hviA: 12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_B_STIB602_0 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.66A	6hd4B-4hviA: 29.1	6hd4B-4hviA: 12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_A_STIA603_0 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 LEU A 956 ALA A 966	19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.64A	6hd6A-4hviA: 29.1	6hd6A-4hviA: 12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_B_STIB601_0 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 (-4.5A)	0.67A	6hd6B-4hviA: 23.9	6hd6B-4hviA: 12.70