SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '18W'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4htg PORPHOBILINOGEN
DEAMINASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 LEU A 199
ALA A 178
LEU A 183
GLN A 210
ARG A 142
 None
None
None
ACT  A 402 ( 4.9A)
18W  A 401 (-3.8A)
 1.26A 1kt6A-4htgA:
undetectable		 1kt6A-4htgA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4htg PORPHOBILINOGEN
DEAMINASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 SER A 140
GLY A 211
GLU A 113
ARG A 142
 18W  A 401 (-2.5A)
None
None
18W  A 401 (-3.8A)
 1.09A 5cdqR-4htgA:
undetectable
5cdqS-4htgA:
undetectable
5cdqT-4htgA:
undetectable		 5cdqR-4htgA:
22.07
5cdqS-4htgA:
22.97
5cdqT-4htgA:
22.07