SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '18C'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 ASN A 213
GLU A 214
HIS A 291
TYR A 293
TRP A 365
 BGC  A 604 (-3.2A)
18C  A 607 (-3.0A)
None
18C  A 607 (-4.0A)
BGC  A 604 (-3.6A)
 0.57A 2v3dA-5j7zA:
7.0		 2v3dA-5j7zA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 GLY A 134
ASP A 133
LEU A 171
ASP A 176
GLU A 214
 None
BGC  A 604 (-2.6A)
None
None
18C  A 607 (-3.0A)
 1.05A 2zw9B-5j7zA:
undetectable		 2zw9B-5j7zA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 ARG A  89
ASP A 129
HIS A 131
ASP A 133
TYR A 293
 None
None
BGC  A 604 (-4.5A)
BGC  A 604 (-2.6A)
18C  A 607 (-4.0A)
 1.49A 3lmyA-5j7zA:
7.1		 3lmyA-5j7zA:
19.70