SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '15O'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA1_1 (CES1 PROTEIN)	4hjl	NAPHTHALENE 1,2-DIOXYGENASE SUBUNIT ALPHA (Pseudomonas sp. C18)	5 / 12	PHE A 224 GLY A 251 LEU A 307 MET A 306 LEU A 170	None None 15O A 503 ( 4.6A) None None	0.97A	1ya4A-4hjlA: undetectable	1ya4A-4hjlA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA1_1 (CES1 PROTEIN)	4hjl	NAPHTHALENE 1,2-DIOXYGENASE SUBUNIT ALPHA (Pseudomonas sp. C18)	5 / 12	PHE A 224 SER A 305 LEU A 307 MET A 306 LEU A 170	None None 15O A 503 ( 4.6A) None None	1.04A	1ya4A-4hjlA: undetectable	1ya4A-4hjlA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_B_RBFB502_1 (RIBOFLAVIN LYASE)	4hjl	NAPHTHALENE 1,2-DIOXYGENASE SUBUNIT ALPHA (Pseudomonas sp. C18)	5 / 12	SER A 406 ALA A 206 GLY A 204 GLY A 390 SER A 412	None 15O A 503 ( 4.3A) None None None	0.93A	5w4zB-4hjlA: undetectable	5w4zB-4hjlA: 11.32