SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '14X'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		7 / 7 TRP A  81
PRO A  82
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
 None
14X  A 201 (-4.4A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
14X  A 201 (-3.5A)
 0.37A 3u5jA-4hbxA:
25.2		 3u5jA-4hbxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		8 / 8 TRP A  81
PRO A  82
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
 None
14X  A 201 (-4.4A)
14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
14X  A 201 (-3.5A)
 0.48A 3u5kA-4hbxA:
25.0		 3u5kA-4hbxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		7 / 7 TRP A  81
PRO A  82
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
 None
14X  A 201 (-4.4A)
14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
 0.49A 3u5kB-4hbxA:
24.6		 3u5kB-4hbxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		8 / 8 TRP A  81
PRO A  82
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
 None
14X  A 201 (-4.4A)
14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
14X  A 201 (-3.5A)
 0.45A 3u5kC-4hbxA:
24.0		 3u5kC-4hbxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		8 / 8 TRP A  81
PRO A  82
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
 None
14X  A 201 (-4.4A)
14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
14X  A 201 (-3.5A)
 0.58A 3u5kD-4hbxA:
24.2		 3u5kD-4hbxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		5 / 5 VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
 14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
 0.38A 4a9jA-4hbxA:
20.5		 4a9jA-4hbxA:
70.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		5 / 5 VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
 14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
 0.39A 4a9jB-4hbxA:
20.8		 4a9jB-4hbxA:
70.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		5 / 5 VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
 14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
 0.47A 4a9jC-4hbxA:
20.0		 4a9jC-4hbxA:
70.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		4 / 6 VAL A  87
LEU A  92
TYR A 139
ASN A 140
 14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
 0.56A 4a9kA-4hbxA:
16.9		 4a9kA-4hbxA:
32.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		9 / 9 TRP A  81
PRO A  82
GLN A  85
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
 None
14X  A 201 (-4.4A)
None
14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
14X  A 201 (-3.5A)
 0.57A 4c66A-4hbxA:
24.7		 4c66A-4hbxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		4 / 7 TYR A  97
MET A 132
ASN A 140
ILE A 146
 None
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
 0.53A 4y03A-4hbxA:
14.3		 4y03A-4hbxA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		4 / 6 PRO A  82
VAL A  87
TYR A  97
ILE A 146
 14X  A 201 (-4.4A)
14X  A 201 (-4.7A)
None
14X  A 201 ( 4.0A)
 0.88A 5pbeA-4hbxA:
15.4		 5pbeA-4hbxA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		4 / 6 VAL A  87
TYR A  97
ASN A 140
ILE A 146
 14X  A 201 (-4.7A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
 0.40A 5pbeA-4hbxA:
15.4		 5pbeA-4hbxA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4
(Homo
sapiens) 		8 / 8 PRO A  82
VAL A  87
LEU A  92
LEU A  94
CYH A 136
TYR A 139
ASN A 140
ILE A 146
 14X  A 201 (-4.4A)
14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 ( 3.9A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
 0.39A 5y1yA-4hbxA:
24.4		 5y1yA-4hbxA:
100.00