SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '14W'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	1qw5	NITRIC OXIDE SYNTHASE, INDUCIBLE (Mus musculus)	4 / 5	PRO A 344 VAL A 346 TYR A 367 MET A 368	14W A 902 ( 4.4A) None None HEM A 900 ( 4.5A)	0.16A	1m8dA-1qw5A: 62.1	1m8dA-1qw5A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_B_CLWB907_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	1qw5	NITRIC OXIDE SYNTHASE, INDUCIBLE (Mus musculus)	4 / 5	PRO A 344 VAL A 346 TYR A 367 MET A 368	14W A 902 ( 4.4A) None None HEM A 900 ( 4.5A)	0.18A	1m8dB-1qw5A: 61.7	1m8dB-1qw5A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	1qw5	NITRIC OXIDE SYNTHASE, INDUCIBLE (Mus musculus)	4 / 5	PRO A 344 VAL A 346 TYR A 367 MET A 368	14W A 902 ( 4.4A) None None HEM A 900 ( 4.5A)	0.26A	1m9jA-1qw5A: 56.3	1m9jA-1qw5A: 62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	1qw5	NITRIC OXIDE SYNTHASE, INDUCIBLE (Mus musculus)	4 / 5	PRO A 344 VAL A 346 TYR A 367 MET A 368	14W A 902 ( 4.4A) None None HEM A 900 ( 4.5A)	0.18A	1m9jB-1qw5A: 56.5	1m9jB-1qw5A: 62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	1qw5	NITRIC OXIDE SYNTHASE, INDUCIBLE (Mus musculus)	4 / 5	VAL A 346 TYR A 367 MET A 368 GLU A 371	None None HEM A 900 ( 4.5A) 14W A 902 ( 3.2A)	1.25A	1m9jB-1qw5A: 56.5	1m9jB-1qw5A: 62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4KCN_A_MTLA804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	1qw5	NITRIC OXIDE SYNTHASE, INDUCIBLE (Mus musculus)	6 / 6	ARG A 260 GLU A 371 ARG A 375 ASP A 376 ASP A 379 ARG A 382	None 14W A 902 ( 3.2A) H4B A 901 (-3.4A) None None None	0.45A	4kcnA-1qw5A: 58.1	4kcnA-1qw5A: 63.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4KCN_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	1qw5	NITRIC OXIDE SYNTHASE, INDUCIBLE (Mus musculus)	6 / 6	ARG A 260 GLU A 371 ARG A 375 ASP A 376 ASP A 379 ARG A 382	None 14W A 902 ( 3.2A) H4B A 901 (-3.4A) None None None	0.45A	4kcnB-1qw5A: 57.9	4kcnB-1qw5A: 63.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1M8D_A_CLWA906_1","INDUCIBLE NITRIC OXIDE SYNTHASE","1qw5","NITRIC OXIDE SYNTHASE, INDUCIBLE","Mus musculus",4,"PRO A 344;VAL A 346;TYR A 367;MET A 368","14W A 902 ( 4.4A);None;None;HEM A 900 ( 4.5A)","0.16A","1m8dA-1qw5A:62.1",null],["1M8D_B_CLWB907_1","INDUCIBLE NITRIC OXIDE SYNTHASE","1qw5","NITRIC OXIDE SYNTHASE, INDUCIBLE","Mus musculus",4,"PRO A 344;VAL A 346;TYR A 367;MET A 368","14W A 902 ( 4.4A);None;None;HEM A 900 ( 4.5A)","0.18A","1m8dB-1qw5A:61.7","1m8dA-1qw5A:100.00"],["1M9J_A_CLWA906_1","ENDOTHELIAL NITRIC-OXIDE SYNTHASE","1qw5","NITRIC OXIDE SYNTHASE, INDUCIBLE","Mus musculus",4,"PRO A 344;VAL A 346;TYR A 367;MET A 368","14W A 902 ( 4.4A);None;None;HEM A 900 ( 4.5A)","0.26A","1m9jA-1qw5A:56.3","1m8dB-1qw5A:100.00"],["1M9J_B_CLWB907_1","ENDOTHELIAL NITRIC-OXIDE SYNTHASE","1qw5","NITRIC OXIDE SYNTHASE, INDUCIBLE","Mus musculus",4,"PRO A 344;VAL A 346;TYR A 367;MET A 368","14W A 902 ( 4.4A);None;None;HEM A 900 ( 4.5A)","0.18A","1m9jB-1qw5A:56.5","1m9jA-1qw5A:62.17"],["1M9J_B_CLWB907_1","ENDOTHELIAL NITRIC-OXIDE SYNTHASE","1qw5","NITRIC OXIDE SYNTHASE, INDUCIBLE","Mus musculus",4,"VAL A 346;TYR A 367;MET A 368;GLU A 371","None;None;HEM A 900 ( 4.5A);14W A 902 ( 3.2A)","1.25A","1m9jB-1qw5A:56.5","1m9jB-1qw5A:62.17"],["4KCN_A_MTLA804_0","NITRIC OXIDE SYNTHASE, BRAIN","1qw5","NITRIC OXIDE SYNTHASE, INDUCIBLE","Mus musculus",6,"ARG A 260;GLU A 371;ARG A 375;ASP A 376;ASP A 379;ARG A 382","None;14W A 902 ( 3.2A);H4B A 901 (-3.4A);None;None;None","0.45A","4kcnA-1qw5A:58.1","1m9jB-1qw5A:62.17"],["4KCN_B_MTLB805_0","NITRIC OXIDE SYNTHASE, BRAIN","1qw5","NITRIC OXIDE SYNTHASE, INDUCIBLE","Mus musculus",6,"ARG A 260;GLU A 371;ARG A 375;ASP A 376;ASP A 379;ARG A 382","None;14W A 902 ( 3.2A);H4B A 901 (-3.4A);None;None;None","0.45A","4kcnB-1qw5A:57.9","4kcnA-1qw5A:63.90"]]