SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '13X'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IGT_C_SAMC1003_0 (SAM DEPENDENT METHYLTRANSFERASE)	5mg5	2,4-DIACETYLPHLOROGL UCINOL BIOSYNTHESIS PROTEIN PHLC (Pseudomonas protegens)	5 / 12	TYR C 55 ALA C 348 SER C 349 GLY C 212 TYR C 63	None None 13X C 500 (-4.2A) None None	1.27A	2igtC-5mg5C: undetectable	2igtC-5mg5C: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KZ7_A_RAPA225_1 (FK506-BINDING PROTEIN 3)	5mg5	2,4-DIACETYLPHLOROGL UCINOL BIOSYNTHESIS PROTEIN PHLC (Pseudomonas protegens)	5 / 10	TYR C 298 ASP C 352 LEU C 300 ILE C 128 TYR C 124	SCY C 88 (-4.2A) None None 13X C 500 (-3.9A) 13X C 500 (-4.9A)	1.17A	3kz7A-5mg5C: undetectable	3kz7A-5mg5C: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DF2_A_4CHA506_0 (NADPH DEHYDROGENASE)	5mg5	2,4-DIACETYLPHLOROGL UCINOL BIOSYNTHESIS PROTEIN PHLC (Pseudomonas protegens)	4 / 6	THR C 89 HIS C 144 HIS C 246 TYR C 241	SCY C 88 ( 3.8A) 13X C 500 (-4.5A) None None	1.35A	4df2A-5mg5C: undetectable	4df2A-5mg5C: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODO_A_FK5A205_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD)	5mg5	2,4-DIACETYLPHLOROGL UCINOL BIOSYNTHESIS PROTEIN PHLC (Pseudomonas protegens)	5 / 10	TYR C 298 ASP C 352 LEU C 300 ILE C 128 TYR C 124	SCY C 88 (-4.2A) None None 13X C 500 (-3.9A) 13X C 500 (-4.9A)	1.08A	4odoA-5mg5C: undetectable	4odoA-5mg5C: 16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODO_C_FK5C204_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD)	5mg5	2,4-DIACETYLPHLOROGL UCINOL BIOSYNTHESIS PROTEIN PHLC (Pseudomonas protegens)	5 / 10	TYR C 298 ASP C 352 LEU C 300 ILE C 128 TYR C 124	SCY C 88 (-4.2A) None None 13X C 500 (-3.9A) 13X C 500 (-4.9A)	1.06A	4odoC-5mg5C: undetectable	4odoC-5mg5C: 16.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2IGT_C_SAMC1003_0","SAM DEPENDENT METHYLTRANSFERASE","5mg5","2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESIS PROTEIN PHLC","Pseudomonas protegens",5,"TYR C  55;ALA C 348;SER C 349;GLY C 212;TYR C  63","None;None;13X C 500 (-4.2A);None;None","1.27A","2igtC-5mg5C:undetectable",null],["3KZ7_A_RAPA225_1","FK506-BINDING PROTEIN 3","5mg5","2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESIS PROTEIN PHLC","Pseudomonas protegens",5,"TYR C 298;ASP C 352;LEU C 300;ILE C 128;TYR C 124","SCY C  88 (-4.2A);None;None;13X C 500 (-3.9A);13X C 500 (-4.9A)","1.17A","3kz7A-5mg5C:undetectable","2igtC-5mg5C:undetectable"],["4DF2_A_4CHA506_0","NADPH DEHYDROGENASE","5mg5","2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESIS PROTEIN PHLC","Pseudomonas protegens",4,"THR C  89;HIS C 144;HIS C 246;TYR C 241","SCY C  88 ( 3.8A);13X C 500 (-4.5A);None;None","1.35A","4df2A-5mg5C:undetectable","3kz7A-5mg5C:18.60"],["4ODO_A_FK5A205_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD","5mg5","2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESIS PROTEIN PHLC","Pseudomonas protegens",5,"TYR C 298;ASP C 352;LEU C 300;ILE C 128;TYR C 124","SCY C  88 (-4.2A);None;None;13X C 500 (-3.9A);13X C 500 (-4.9A)","1.08A","4odoA-5mg5C:undetectable","4df2A-5mg5C:undetectable"],["4ODO_C_FK5C204_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD","5mg5","2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESIS PROTEIN PHLC","Pseudomonas protegens",5,"TYR C 298;ASP C 352;LEU C 300;ILE C 128;TYR C 124","SCY C  88 (-4.2A);None;None;13X C 500 (-3.9A);13X C 500 (-4.9A)","1.06A","4odoC-5mg5C:undetectable","4odoA-5mg5C:16.00"]]