SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '10A'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHV_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1kph	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 1 (Mycobacterium tuberculosis)	5 / 8	THR A 168 GLY A 137 GLY A 143 PHE A 139 GLY A 203	None CO3  A1902 (-3.1A) None None 10A  A1901 (-3.7A)	1.38A	1jhvA-1kphA: undetectable	1jhvA-1kphA: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F10_A_BCZA382_0 (SIALIDASE 2)	1kpi	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	ILE A 184 GLU A 148 TYR A 280 LEU A 281 TYR A 247	CO3  A 902 ( 4.5A) CO3  A 902 ( 3.4A) None None 10A  A 901 ( 4.3A)	1.12A	2f10A-1kpiA: undetectable	2f10A-1kpiA: 22.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2FK8_A_SAMA302_0 (METHOXY MYCOLIC ACID SYNTHASE 4)	1kph	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 1 (Mycobacterium tuberculosis)	11 / 12	THR A  32 TYR A  33 GLY A  72 GLY A  74 LEU A  95 GLY A 122 TRP A 123 GLU A 124 ILE A 136 ALA A 138 HIS A 141	SAH  A1900 (-4.1A) 10A  A1901 ( 3.5A) SAH  A1900 (-3.1A) SAH  A1900 (-3.2A) SAH  A1900 (-4.4A) SAH  A1900 (-3.2A) SAH  A1900 (-4.3A) SAH  A1900 (-2.9A) SAH  A1900 (-4.2A) SAH  A1900 (-3.2A) SAH  A1900 (-4.4A)	0.43A	2fk8A-1kphA: 40.6	2fk8A-1kphA: 54.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2FK8_A_SAMA302_0 (METHOXY MYCOLIC ACID SYNTHASE 4)	1kpi	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 2 (Mycobacterium tuberculosis)	11 / 12	THR A  40 TYR A  41 ILE A  79 GLY A  80 GLY A  82 LEU A 103 GLY A 130 TRP A 131 GLU A 132 ALA A 146 HIS A 149	SAH  A 900 (-4.4A) 10A  A 901 ( 3.7A) None SAH  A 900 (-3.3A) SAH  A 900 (-3.1A) SAH  A 900 (-4.4A) SAH  A 900 (-3.3A) SAH  A 900 (-4.5A) SAH  A 900 (-3.1A) SAH  A 900 (-3.1A) SAH  A 900 (-4.3A)	0.55A	2fk8A-1kpiA: 36.9	2fk8A-1kpiA: 47.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OPX_A_DXCA1001_0 (ALDEHYDE DEHYDROGENASE A)	1kph	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 1 (Mycobacterium tuberculosis)	4 / 7	LEU A 205 PHE A 191 ILE A 169 PHE A 273	10A  A1901 (-3.9A) None 10A  A1901 ( 4.7A) None	0.90A	2opxA-1kphA: 4.4	2opxA-1kphA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_C_SALC1302_1 (LYSR-TYPE REGULATORY PROTEIN)	1kpi	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	ILE A 243 GLY A 244 TYR A 247 PHE A 288 HIS A 182	None None 10A  A 901 ( 4.3A) 10A  A 901 ( 4.9A) CO3  A 902 (-3.8A)	1.22A	2y7kC-1kpiA: undetectable	2y7kC-1kpiA: 23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW7_A_VPXA2001_1 (PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME)	1kph	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 1 (Mycobacterium tuberculosis)	5 / 12	TYR A  33 HIS A  15 LEU A 243 LEU A 266 ALA A 250	10A  A1901 ( 3.5A) None None None None	1.06A	3vw7A-1kphA: undetectable	3vw7A-1kphA: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M51_A_BEZA501_0 (AMIDOHYDROLASE FAMILY PROTEIN)	1kpi	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 2 (Mycobacterium tuberculosis)	4 / 6	ILE A 184 ILE A 210 PHE A 288 LEU A 251	CO3  A 902 ( 4.5A) None 10A  A 901 ( 4.9A) None	0.99A	4m51A-1kpiA: 0.1	4m51A-1kpiA: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_B_BRLB501_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1kph	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 1 (Mycobacterium tuberculosis)	4 / 6	GLY A 276 ILE A 208 ILE A 177 LEU A 192	None None None 10A  A1901 (-3.7A)	0.74A	4o8fB-1kphA: undetectable	4o8fB-1kphA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_A_PCFA1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	1kph	CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE 1 (Mycobacterium tuberculosis)	5 / 7	LEU A 266 ILE A 278 GLY A 171 LEU A 205 ILE A 199	None 10A  A1901 ( 4.4A) None 10A  A1901 (-3.9A) None	1.31A	5vkqA-1kphA: 2.4 5vkqB-1kphA: 2.4	5vkqA-1kphA: 10.16 5vkqB-1kphA: 10.16