SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0XW'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_C_DVAC8_0 (GRAMICIDIN A)	4h2h	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Salipiger bermudensis)	3 / 4	VAL A 52 TRP A 28 TRP A 295	0XW A 403 ( 4.6A) None None	1.38A	1gmkC-4h2hA: undetectable 1gmkD-4h2hA: undetectable	1gmkC-4h2hA: 3.88 1gmkD-4h2hA: 3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BUE_A_RIOA1201_0 (AAC(6')-IB)	4h2h	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Salipiger bermudensis)	5 / 11	TRP A 320 TYR A 325 TYR A 56 SER A 24 ASP A 241	0XW A 403 (-4.0A) None 0XW A 403 (-4.7A) None MG A 401 ( 3.1A)	1.13A	2bueA-4h2hA: 0.4	2bueA-4h2hA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	4h2h	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Salipiger bermudensis)	5 / 8	GLY A 318 ALA A 319 ASP A 292 PRO A 346 ILE A 343	None None 0XW A 403 ( 4.4A) None None	1.28A	3el0A-4h2hA: undetectable	3el0A-4h2hA: 13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_A_PARA500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	4h2h	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Salipiger bermudensis)	5 / 10	PHE A 281 ASP A 293 ASP A 292 TYR A 239 GLY A 263	None None 0XW A 403 ( 4.4A) None None	1.38A	4qb9A-4h2hA: undetectable	4qb9A-4h2hA: 24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_C_PARC500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	4h2h	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Salipiger bermudensis)	5 / 10	PHE A 281 ASP A 293 ASP A 292 TYR A 239 GLY A 263	None None 0XW A 403 ( 4.4A) None None	1.46A	4qb9C-4h2hA: undetectable	4qb9C-4h2hA: 24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_E_PARE500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	4h2h	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Salipiger bermudensis)	5 / 12	PHE A 281 ASP A 293 ASP A 292 TYR A 239 GLY A 263	None None 0XW A 403 ( 4.4A) None None	1.48A	4qb9E-4h2hA: undetectable	4qb9E-4h2hA: 24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB302_1 (CHITOSANASE)	4h2h	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Salipiger bermudensis)	4 / 5	GLU A 218 TYR A 134 THR A 290 TYR A 56	MG A 401 ( 2.9A) None None 0XW A 403 (-4.7A)	1.33A	4qwpB-4h2hA: undetectable	4qwpB-4h2hA: 23.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GMK_C_DVAC8_0","GRAMICIDIN A","4h2h","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME","Salipiger bermudensis",3,"VAL A  52;TRP A  28;TRP A 295","0XW A 403 ( 4.6A);None;None","1.38A","1gmkC-4h2hA:undetectable;1gmkD-4h2hA:undetectable",null],["2BUE_A_RIOA1201_0","AAC(6')-IB","4h2h","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME","Salipiger bermudensis",5,"TRP A 320;TYR A 325;TYR A  56;SER A  24;ASP A 241","0XW A 403 (-4.0A);None;0XW A 403 (-4.7A);None; MG A 401 ( 3.1A)","1.13A","2bueA-4h2hA:0.4","1gmkC-4h2hA:3.88;1gmkD-4h2hA:3.88"],["3EL0_A_1UNA201_1","PROTEASE","4h2h","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME","Salipiger bermudensis",5,"GLY A 318;ALA A 319;ASP A 292;PRO A 346;ILE A 343","None;None;0XW A 403 ( 4.4A);None;None","1.28A","3el0A-4h2hA:undetectable","2bueA-4h2hA:18.21"],["4QB9_A_PARA500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","4h2h","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME","Salipiger bermudensis",5,"PHE A 281;ASP A 293;ASP A 292;TYR A 239;GLY A 263","None;None;0XW A 403 ( 4.4A);None;None","1.38A","4qb9A-4h2hA:undetectable","3el0A-4h2hA:13.82"],["4QB9_C_PARC500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","4h2h","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME","Salipiger bermudensis",5,"PHE A 281;ASP A 293;ASP A 292;TYR A 239;GLY A 263","None;None;0XW A 403 ( 4.4A);None;None","1.46A","4qb9C-4h2hA:undetectable","4qb9A-4h2hA:24.45"],["4QB9_E_PARE500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","4h2h","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME","Salipiger bermudensis",5,"PHE A 281;ASP A 293;ASP A 292;TYR A 239;GLY A 263","None;None;0XW A 403 ( 4.4A);None;None","1.48A","4qb9E-4h2hA:undetectable","4qb9C-4h2hA:24.45"],["4QWP_B_GCSB302_1","CHITOSANASE","4h2h","MANDELATE RACEMASE\/MUCONATE LACTONIZING ENZYME","Salipiger bermudensis",4,"GLU A 218;TYR A 134;THR A 290;TYR A  56"," MG A 401 ( 2.9A);None;None;0XW A 403 (-4.7A)","1.33A","4qwpB-4h2hA:undetectable","4qb9E-4h2hA:24.45"]]