SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0XT'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_2 (PHOSPHOLIPASE A2)	4glw	DNA LIGASE (Streptococcus pneumoniae)	4 / 5	VAL A 275 VAL A 276 GLN A 80 ARG A 94	None 0XT A 402 (-4.6A) None None	1.35A	3bjwB-4glwA: undetectable	3bjwB-4glwA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QWU_A_ADNA501_1 (DNA LIGASE)	4glw	DNA LIGASE (Streptococcus pneumoniae)	5 / 12	GLU A 107 LYS A 109 GLU A 164 VAL A 276 LYS A 278	0XT A 402 (-3.7A) 0XT A 402 ( 4.4A) 0XT A 402 ( 4.5A) 0XT A 402 (-4.6A) 0XT A 402 (-2.8A)	0.52A	3qwuA-4glwA: 10.5	3qwuA-4glwA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QWU_B_ADNB501_1 (DNA LIGASE)	4glw	DNA LIGASE (Streptococcus pneumoniae)	5 / 11	GLU A 107 LYS A 109 GLU A 164 VAL A 276 LYS A 278	0XT A 402 (-3.7A) 0XT A 402 ( 4.4A) 0XT A 402 ( 4.5A) 0XT A 402 (-4.6A) 0XT A 402 (-2.8A)	0.52A	3qwuB-4glwA: 11.1	3qwuB-4glwA: 22.82