SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0X9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BTE_A_LEUA1894_0 (AMINOACYL-TRNA SYNTHETASE)	6f79	- (-)	4 / 8	ASP A 260 TYR A 149 HIS A 69 HIS A 68	0X9 A 407 (-4.3A) None ZN A 401 ( 3.1A) None	1.25A	2bteA-6f79A: undetectable	2bteA-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BTE_D_LEUD1893_0 (AMINOACYL-TRNA SYNTHETASE)	6f79	- (-)	4 / 8	ASP A 260 TYR A 149 HIS A 69 HIS A 68	0X9 A 407 (-4.3A) None ZN A 401 ( 3.1A) None	1.21A	2bteD-6f79A: 1.4	2bteD-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYT_A_LEUA1301_0 (LEUCYL-TRNA SYNTHETASE)	6f79	- (-)	4 / 7	ASP A 260 TYR A 149 HIS A 69 HIS A 68	0X9 A 407 (-4.3A) None ZN A 401 ( 3.1A) None	1.27A	2bytA-6f79A: undetectable	2bytA-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYT_D_LEUD1601_0 (LEUCYL-TRNA SYNTHETASE)	6f79	- (-)	4 / 7	ASP A 260 TYR A 149 HIS A 69 HIS A 68	0X9 A 407 (-4.3A) None ZN A 401 ( 3.1A) None	1.26A	2bytD-6f79A: undetectable	2bytD-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_B_NCAB1246_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	6f79	- (-)	4 / 7	GLY A 286 SER A 207 PHE A 287 GLU A 277	None None None 0X9 A 407 (-3.2A)	1.02A	2c8aB-6f79A: undetectable	2c8aB-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_D_NCAD1247_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	6f79	- (-)	4 / 7	GLY A 286 SER A 207 PHE A 287 GLU A 277	None None None 0X9 A 407 (-3.2A)	1.09A	2c8aD-6f79A: undetectable	2c8aD-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0G_A_LEUA1887_0 (AMINOACYL-TRNA SYNTHETASE)	6f79	- (-)	4 / 8	ASP A 260 TYR A 149 HIS A 69 HIS A 68	0X9 A 407 (-4.3A) None ZN A 401 ( 3.1A) None	1.24A	2v0gA-6f79A: 1.7	2v0gA-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_A_HSMA1162_1 (ALLERGEN ARG R 1)	6f79	- (-)	4 / 4	GLU A 277 ASP A 144 HIS A 69 GLU A 72	0X9 A 407 (-3.2A) 0X9 A 407 ( 4.9A) ZN A 401 ( 3.1A) ZN A 401 ( 1.9A)	1.48A	2x45A-6f79A: undetectable	2x45A-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_B_HSMB1162_1 (ALLERGEN ARG R 1)	6f79	- (-)	3 / 3	GLU A 277 HIS A 69 GLU A 72	0X9 A 407 (-3.2A) ZN A 401 ( 3.1A) ZN A 401 ( 1.9A)	0.77A	2x45B-6f79A: undetectable	2x45B-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_C_HSMC1162_1 (ALLERGEN ARG R 1)	6f79	- (-)	3 / 3	GLU A 277 HIS A 69 GLU A 72	0X9 A 407 (-3.2A) ZN A 401 ( 3.1A) ZN A 401 ( 1.9A)	0.80A	2x45C-6f79A: undetectable	2x45C-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_I_Z80I401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	6f79	- (-)	4 / 9	PHE A 174 ASN A 146 ASP A 263 TRP A 264	None 0X9 A 407 (-3.9A) None SO4 A 406 (-3.8A)	1.02A	5lg3I-6f79A: undetectable	5lg3I-6f79A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G31_B_ZOLB401_0 (GERANYLGERANYL PYROPHOSPHATE SYNTHASE)	6f79	- (-)	4 / 6	ASP A 260 ASP A 263 ARG A 147 GLN A 211	0X9 A 407 (-4.3A) None 0X9 A 407 (-2.9A) 0X9 A 407 (-3.0A)	1.39A	6g31B-6f79A: undetectable	6g31B-6f79A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BTE_A_LEUA1894_0","AMINOACYL-TRNA SYNTHETASE","6f79","-","-",4,"ASP A 260;TYR A 149;HIS A  69;HIS A  68","0X9 A 407 (-4.3A);None; ZN A 401 ( 3.1A);None","1.25A","2bteA-6f79A:undetectable",null],["2BTE_D_LEUD1893_0","AMINOACYL-TRNA SYNTHETASE","6f79","-","-",4,"ASP A 260;TYR A 149;HIS A  69;HIS A  68","0X9 A 407 (-4.3A);None; ZN A 401 ( 3.1A);None","1.21A","2bteD-6f79A:1.4","2bteA-6f79A:undetectable"],["2BYT_A_LEUA1301_0","LEUCYL-TRNA SYNTHETASE","6f79","-","-",4,"ASP A 260;TYR A 149;HIS A  69;HIS A  68","0X9 A 407 (-4.3A);None; ZN A 401 ( 3.1A);None","1.27A","2bytA-6f79A:undetectable","2bteD-6f79A:undetectable"],["2BYT_D_LEUD1601_0","LEUCYL-TRNA SYNTHETASE","6f79","-","-",4,"ASP A 260;TYR A 149;HIS A  69;HIS A  68","0X9 A 407 (-4.3A);None; ZN A 401 ( 3.1A);None","1.26A","2bytD-6f79A:undetectable","2bytA-6f79A:undetectable"],["2C8A_B_NCAB1246_0","MONO-ADP-RIBOSYLTRANSFERASE C3","6f79","-","-",4,"GLY A 286;SER A 207;PHE A 287;GLU A 277","None;None;None;0X9 A 407 (-3.2A)","1.02A","2c8aB-6f79A:undetectable","2bytD-6f79A:undetectable"],["2C8A_D_NCAD1247_0","MONO-ADP-RIBOSYLTRANSFERASE C3","6f79","-","-",4,"GLY A 286;SER A 207;PHE A 287;GLU A 277","None;None;None;0X9 A 407 (-3.2A)","1.09A","2c8aD-6f79A:undetectable","2c8aB-6f79A:undetectable"],["2V0G_A_LEUA1887_0","AMINOACYL-TRNA SYNTHETASE","6f79","-","-",4,"ASP A 260;TYR A 149;HIS A  69;HIS A  68","0X9 A 407 (-4.3A);None; ZN A 401 ( 3.1A);None","1.24A","2v0gA-6f79A:1.7","2c8aD-6f79A:undetectable"],["2X45_A_HSMA1162_1","ALLERGEN ARG R 1","6f79","-","-",4,"GLU A 277;ASP A 144;HIS A  69;GLU A  72","0X9 A 407 (-3.2A);0X9 A 407 ( 4.9A); ZN A 401 ( 3.1A); ZN A 401 ( 1.9A)","1.48A","2x45A-6f79A:undetectable","2v0gA-6f79A:undetectable"],["2X45_B_HSMB1162_1","ALLERGEN ARG R 1","6f79","-","-",3,"GLU A 277;HIS A  69;GLU A  72","0X9 A 407 (-3.2A); ZN A 401 ( 3.1A); ZN A 401 ( 1.9A)","0.77A","2x45B-6f79A:undetectable","2x45A-6f79A:undetectable"],["2X45_C_HSMC1162_1","ALLERGEN ARG R 1","6f79","-","-",3,"GLU A 277;HIS A  69;GLU A  72","0X9 A 407 (-3.2A); ZN A 401 ( 3.1A); ZN A 401 ( 1.9A)","0.80A","2x45C-6f79A:undetectable","2x45B-6f79A:undetectable"],["5LG3_I_Z80I401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","6f79","-","-",4,"PHE A 174;ASN A 146;ASP A 263;TRP A 264","None;0X9 A 407 (-3.9A);None;SO4 A 406 (-3.8A)","1.02A","5lg3I-6f79A:undetectable","2x45C-6f79A:undetectable"],["6G31_B_ZOLB401_0","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","6f79","-","-",4,"ASP A 260;ASP A 263;ARG A 147;GLN A 211","0X9 A 407 (-4.3A);None;0X9 A 407 (-2.9A);0X9 A 407 (-3.0A)","1.39A","6g31B-6f79A:undetectable","5lg3I-6f79A:undetectable"]]