SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0T8'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_B_STIB202_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 6 / 12 | LEU A 514VAL A 522ALA A 538PHE A 595GLY A 599ALA A 662 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A) | 0.66A | 1iepB-4feqA:22.8 | 1iepB-4feqA:39.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FUM_A_MIXA539_1 (PROBABLESERINE/THREONINE-PROTEIN KINASE PKNB) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 12 | LEU A 514GLY A 515VAL A 522ALA A 538ASP A 645ASN A 650MET A 652 | 0T8 A 901 (-3.6A)0T8 A 901 ( 3.9A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)NoneNone0T8 A 901 (-3.9A) | 0.97A | 2fumA-4feqA:16.3 | 2fumA-4feqA:26.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ITZ_A_IREA2021_2 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 3 / 3 | LEU A 606LEU A 653MET A 652 | NoneNone0T8 A 901 (-3.9A) | 0.75A | 2itzA-4feqA:25.4 | 2itzA-4feqA:34.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTHFACTOR RECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | GLY A 515VAL A 522ALA A 538LEU A 593MET A 596GLY A 599MET A 652ALA A 662 | 0T8 A 901 ( 3.9A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A)0T8 A 901 (-3.9A)0T8 A 901 ( 4.5A) | 0.81A | 2wgjA-4feqA:29.6 | 2wgjA-4feqA:41.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTHFACTOR RECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | GLY A 515VAL A 522ALA A 538MET A 596GLY A 599MET A 652ALA A 662ASP A 663 | 0T8 A 901 ( 3.9A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)None0T8 A 901 ( 3.8A)0T8 A 901 (-3.9A)0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.92A | 2wgjA-4feqA:29.6 | 2wgjA-4feqA:41.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2XP2_A_VGHA9000_1 (TYROSINE-PROTEINKINASE RECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 9 | LEU A 514VAL A 522ALA A 538LEU A 593MET A 596GLY A 599ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A)0T8 A 901 (-4.5A) | 0.88A | 2xp2A-4feqA:28.1 | 2xp2A-4feqA:36.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 12 | LEU A 514GLY A 515GLU A 524ALA A 538LYS A 540PHE A 595GLY A 599 | 0T8 A 901 (-3.6A)0T8 A 901 ( 3.9A)None0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A) | 0.70A | 3c7qA-4feqA:24.7 | 3c7qA-4feqA:37.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_C_NILC600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 5 / 12 | ALA A 538PHE A 595PHE A 641HIS A 643ALA A 662 | 0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)NoneNone0T8 A 901 ( 4.5A) | 0.64A | 3cs9C-4feqA:23.6 | 3cs9C-4feqA:39.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_C_NILC600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 5 / 12 | PHE A 595PHE A 641HIS A 643ALA A 662ASP A 663 | 0T8 A 901 (-3.9A)NoneNone0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.81A | 3cs9C-4feqA:23.6 | 3cs9C-4feqA:39.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_D_NILD600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 6 / 12 | ALA A 538PHE A 595GLY A 599PHE A 641HIS A 643ALA A 662 | 0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)NoneNone0T8 A 901 ( 4.5A) | 0.60A | 3cs9D-4feqA:23.1 | 3cs9D-4feqA:39.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MIY_B_B49B2_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 5 / 9 | ALA A 538LYS A 540PHE A 595MET A 596GLY A 599 | 0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.9A)None0T8 A 901 ( 3.8A) | 0.72A | 3miyB-4feqA:24.8 | 3miyB-4feqA:34.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 6 / 12 | LEU A 514VAL A 522ALA A 538PHE A 595GLY A 599ALA A 662 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A) | 0.60A | 3ms9B-4feqA:22.7 | 3ms9B-4feqA:39.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 6 / 12 | LEU A 514VAL A 522ALA A 538PHE A 595GLY A 599ALA A 662 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A) | 0.67A | 3mssB-4feqA:23.0 | 3mssB-4feqA:39.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_D_STID1_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 6 / 12 | LEU A 514ALA A 538PHE A 595GLY A 599ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.83A | 3mssD-4feqA:23.0 | 3mssD-4feqA:39.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3WZE_A_BAXA1201_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540PHE A 595GLY A 599LEU A 636HIS A 643 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)NoneNone | 0.74A | 3wzeA-4feqA:22.5 | 3wzeA-4feqA:37.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ZBF_A_VGHA3000_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ROS) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 6 / 12 | LEU A 514ALA A 538MET A 596GLY A 599ASP A 600ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 (-3.2A)None0T8 A 901 ( 3.8A)0T8 A 901 (-3.9A)0T8 A 901 (-4.5A) | 0.93A | 3zbfA-4feqA:29.3 | 3zbfA-4feqA:39.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 9 | LEU A 514VAL A 522ALA A 538LEU A 593MET A 596GLY A 599ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.89A | 4anqA-4feqA:16.8 | 4anqA-4feqA:35.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ANS_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 9 | LEU A 514VAL A 522ALA A 538MET A 596GLY A 599ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)None0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.86A | 4ansA-4feqA:22.2 | 4ansA-4feqA:35.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ASD_A_BAXA1500_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540PHE A 595GLY A 599LEU A 636HIS A 643 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)NoneNone | 0.75A | 4asdA-4feqA:22.4 | 4asdA-4feqA:34.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MKC_A_4MKA1503_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540GLY A 599ASP A 600ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 ( 3.8A)0T8 A 901 (-3.9A)0T8 A 901 (-4.5A) | 0.85A | 4mkcA-4feqA:11.0 | 4mkcA-4feqA:33.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MKC_A_4MKA1503_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540LEU A 593GLY A 599ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.7A)0T8 A 901 ( 3.8A)0T8 A 901 (-4.5A) | 1.01A | 4mkcA-4feqA:11.0 | 4mkcA-4feqA:33.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_A_AXIA601_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 9 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540PHE A 595MET A 596GLY A 599ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.9A)None0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.97A | 4twpA-4feqA:23.1 | 4twpA-4feqA:40.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_A_AXIA601_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | LEU A 514VAL A 522ALA A 538PHE A 595GLY A 599ASN A 650ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)None0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.77A | 4twpA-4feqA:23.1 | 4twpA-4feqA:40.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_B_AXIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540PHE A 595MET A 596GLY A 599ALA A 662 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.9A)None0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A) | 0.82A | 4twpB-4feqA:22.9 | 4twpB-4feqA:40.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_B_AXIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | LEU A 514VAL A 522ALA A 538PHE A 595GLY A 599ASN A 650ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)None0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.80A | 4twpB-4feqA:22.9 | 4twpB-4feqA:40.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_B_AXIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 8 / 12 | LEU A 514VAL A 522ALA A 538PHE A 595MET A 596GLY A 599ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)None0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.78A | 4twpB-4feqA:22.9 | 4twpB-4feqA:40.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4V04_B_0LIB1771_2 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 5 / 12 | MET A 562LEU A 636HIS A 643ALA A 662ASP A 663 | NoneNoneNone0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.91A | 4v04B-4feqA:25.1 | 4v04B-4feqA:39.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XEY_A_1N1A601_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540PHE A 595GLY A 599ALA A 662 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A) | 0.69A | 4xeyA-4feqA:25.0 | 4xeyA-4feqA:33.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAA_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 9 | LEU A 514VAL A 522ALA A 538LEU A 593MET A 596GLY A 599ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A)0T8 A 901 (-4.5A) | 0.90A | 5aaaA-4feqA:20.2 | 5aaaA-4feqA:37.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAB_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 10 | LEU A 514VAL A 522ALA A 538LEU A 593MET A 596GLY A 599ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A)0T8 A 901 (-4.5A) | 0.87A | 5aabA-4feqA:10.7 | 5aabA-4feqA:37.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAB_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 10 | LEU A 514VAL A 522ALA A 538LYS A 540LEU A 593MET A 596GLY A 599 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A) | 0.67A | 5aabA-4feqA:10.7 | 5aabA-4feqA:37.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAC_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 10 | LEU A 514VAL A 522ALA A 538LEU A 593MET A 596GLY A 599ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A)0T8 A 901 (-4.5A) | 0.91A | 5aacA-4feqA:10.6 | 5aacA-4feqA:36.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAC_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 10 | LEU A 514VAL A 522ALA A 538LYS A 540LEU A 593MET A 596GLY A 599 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 (-3.7A)None0T8 A 901 ( 3.8A) | 0.67A | 5aacA-4feqA:10.6 | 5aacA-4feqA:36.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AJQ_A_DB8A800_1 (SERINE/THREONINE-PROTEIN KINASE 10) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 7 / 12 | LEU A 514GLY A 515ALA A 538PHE A 595GLY A 599ALA A 662ASP A 663 | 0T8 A 901 (-3.6A)0T8 A 901 ( 3.9A)0T8 A 901 (-3.2A)0T8 A 901 (-3.9A)0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A)0T8 A 901 (-4.5A) | 0.71A | 5ajqA-4feqA:23.0 | 5ajqA-4feqA:27.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5NKN_A_LOCA201_2 (NEUTROPHILGELATINASE-ASSOCIATED LIPOCALIN) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 3 / 3 | VAL A 574LYS A 540MET A 541 | None0T8 A 901 (-3.5A)None | 0.85A | 5nknA-4feqA:undetectable | 5nknA-4feqA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XV7_A_EMHA705_1 (SERINE-ARGININE (SR)PROTEIN KINASE 1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 5 / 12 | LEU A 514GLY A 515VAL A 522ALA A 538ALA A 662 | 0T8 A 901 (-3.6A)0T8 A 901 ( 3.9A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 ( 4.5A) | 0.32A | 5xv7A-4feqA:19.2 | 5xv7A-4feqA:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZV2_B_LEVB801_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 6 / 12 | LEU A 514VAL A 522ALA A 538LYS A 540GLY A 599ALA A 662 | 0T8 A 901 (-3.6A)0T8 A 901 ( 4.4A)0T8 A 901 (-3.2A)0T8 A 901 (-3.5A)0T8 A 901 ( 3.8A)0T8 A 901 ( 4.5A) | 0.71A | 5zv2B-4feqA:25.4 | 5zv2B-4feqA:13.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6HD4_B_STIB602_1 (TYROSINE-PROTEINKINASE ABL1) |
4feq | TYROSINE-PROTEINKINASE RECEPTORTYRO3 (Musmusculus) | 4 / 6 | LEU A 514PHE A 595MET A 596GLY A 599 | 0T8 A 901 (-3.6A)0T8 A 901 (-3.9A)None0T8 A 901 ( 3.8A) | 0.62A | 6hd4B-4feqA:22.2 | 6hd4B-4feqA:30.89 |