SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0SF'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y69_C_CHDC1265_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.22A	2y69C-4f2aA: undetectable 2y69J-4f2aA: undetectable	2y69C-4f2aA: 19.43 2y69J-4f2aA: 12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y69_P_CHDP1265_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.29A	2y69P-4f2aA: undetectable 2y69W-4f2aA: undetectable	2y69P-4f2aA: 19.43 2y69W-4f2aA: 12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.24A	3abmC-4f2aA: undetectable 3abmJ-4f2aA: undetectable	3abmC-4f2aA: 19.43 3abmJ-4f2aA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.25A	3abmP-4f2aA: undetectable 3abmW-4f2aA: undetectable	3abmP-4f2aA: 19.43 3abmW-4f2aA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.25A	3ag3C-4f2aA: undetectable 3ag3J-4f2aA: undetectable	3ag3C-4f2aA: 19.43 3ag3J-4f2aA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZU_A_X89A411_1 (FLAVOHEMOPROTEIN)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	5 / 12	ILE A 11 PHE A 263 LEU A 457 ALA A 373 LEU A 380	0SF A 610 (-3.2A) 0SF A 610 ( 4.1A) 2OB A 606 (-4.5A) 2OB A 606 ( 3.8A) None	0.99A	3ozuA-4f2aA: undetectable	3ozuA-4f2aA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MSD_A_BEZA1202_0 (CARBOXYLIC ACID REDUCTASE)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	HIS A 232 ILE A 215 PHE A 263 ALA A 202	0SF A 610 (-3.3A) 0SF A 610 (-3.4A) 0SF A 610 ( 4.1A) 0SF A 610 (-2.6A)	1.18A	5msdA-4f2aA: undetectable	5msdA-4f2aA: 17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.20A	5wauC-4f2aA: undetectable 5wauJ-4f2aA: undetectable	5wauC-4f2aA: 19.43 5wauJ-4f2aA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.22A	5wauc-4f2aA: undetectable 5wauj-4f2aA: undetectable	5wauc-4f2aA: 19.43 5wauj-4f2aA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDQ_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.24A	5xdqC-4f2aA: undetectable 5xdqJ-4f2aA: undetectable	5xdqC-4f2aA: 19.43 5xdqJ-4f2aA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDQ_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4f2a	CHOLESTERYL ESTER TRANSFER PROTEIN (Homo sapiens)	4 / 5	PHE A 463 PHE A 461 LEU A 261 PHE A 263	2OB A 605 (-4.6A) 2OB A 605 (-3.9A) 0SF A 610 ( 4.3A) 0SF A 610 ( 4.1A)	1.25A	5xdqP-4f2aA: undetectable 5xdqW-4f2aA: undetectable	5xdqP-4f2aA: 19.43 5xdqW-4f2aA: 13.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y69_C_CHDC1265_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.22A","2y69C-4f2aA:undetectable;2y69J-4f2aA:undetectable",null],["2Y69_P_CHDP1265_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.29A","2y69P-4f2aA:undetectable;2y69W-4f2aA:undetectable","2y69C-4f2aA:19.43;2y69J-4f2aA:12.89"],["3ABM_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.24A","3abmC-4f2aA:undetectable;3abmJ-4f2aA:undetectable","2y69P-4f2aA:19.43;2y69W-4f2aA:12.89"],["3ABM_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.25A","3abmP-4f2aA:undetectable;3abmW-4f2aA:undetectable","3abmC-4f2aA:19.43;3abmJ-4f2aA:13.91"],["3AG3_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.25A","3ag3C-4f2aA:undetectable;3ag3J-4f2aA:undetectable","3abmP-4f2aA:19.43;3abmW-4f2aA:13.91"],["3OZU_A_X89A411_1","FLAVOHEMOPROTEIN","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",5,"ILE A  11;PHE A 263;LEU A 457;ALA A 373;LEU A 380","0SF A 610 (-3.2A);0SF A 610 ( 4.1A);2OB A 606 (-4.5A);2OB A 606 ( 3.8A);None","0.99A","3ozuA-4f2aA:undetectable","3ag3C-4f2aA:19.43;3ag3J-4f2aA:13.91"],["5MSD_A_BEZA1202_0","CARBOXYLIC ACID REDUCTASE","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"HIS A 232;ILE A 215;PHE A 263;ALA A 202","0SF A 610 (-3.3A);0SF A 610 (-3.4A);0SF A 610 ( 4.1A);0SF A 610 (-2.6A)","1.18A","5msdA-4f2aA:undetectable","3ozuA-4f2aA:21.78"],["5WAU_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.20A","5wauC-4f2aA:undetectable;5wauJ-4f2aA:undetectable","5msdA-4f2aA:17.44"],["5WAU_C_CHDC308_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.22A","5wauc-4f2aA:undetectable;5wauj-4f2aA:undetectable","5wauC-4f2aA:19.43;5wauJ-4f2aA:13.91"],["5XDQ_C_CHDC308_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.24A","5xdqC-4f2aA:undetectable;5xdqJ-4f2aA:undetectable","5wauc-4f2aA:19.43;5wauj-4f2aA:13.91"],["5XDQ_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4f2a","CHOLESTERYL ESTER TRANSFER PROTEIN","Homo sapiens",4,"PHE A 463;PHE A 461;LEU A 261;PHE A 263","2OB A 605 (-4.6A);2OB A 605 (-3.9A);0SF A 610 ( 4.3A);0SF A 610 ( 4.1A)","1.25A","5xdqP-4f2aA:undetectable;5xdqW-4f2aA:undetectable","5xdqC-4f2aA:19.43;5xdqJ-4f2aA:13.91"]]