SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0L1'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 5d2j 4-OXALOCROTONATE
DECARBOXYLASE NAHK
(Pseudomonas
putida) 		5 / 12 ASP A  99
ARG A 147
SER A 164
ILE A 144
PHE A 151
 None
None
0L1  A 303 (-2.6A)
0L1  A 303 ( 4.6A)
None
 1.37A 3ua1A-5d2jA:
undetectable		 3ua1A-5d2jA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 5d2j 4-OXALOCROTONATE
DECARBOXYLASE NAHK
(Pseudomonas
putida) 		4 / 8 SER A 164
SER A 146
HIS A 105
ILE A  27
 0L1  A 303 (-2.6A)
0L1  A 303 ( 4.7A)
None
None
 1.29A 4ms4A-5d2jA:
undetectable		 4ms4A-5d2jA:
21.24