SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0HK'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 10 ALA A 111
ASN A 115
ALA A  70
ALA A 108
SER A 109
 None
None
None
None
0HK  A 501 (-3.1A)
 1.45A 2r2vC-5cxvA:
undetectable
2r2vF-5cxvA:
undetectable
2r2vG-5cxvA:
undetectable		 2r2vC-5cxvA:
7.18
2r2vF-5cxvA:
7.18
2r2vG-5cxvA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 SER A  78
TYR A 408
ILE A  73
ASP A 105
 None
0HK  A 501 (-4.7A)
None
0HK  A 501 (-3.0A)
 1.22A 2x45B-5cxvA:
undetectable		 2x45B-5cxvA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 SER A  85
TYR A 439
ILE A  81
ASP A 112
 None
0HK  A1201 (-3.6A)
None
0HK  A1201 (-4.0A)
 1.26A 2x45B-5dsgA:
undetectable		 2x45B-5dsgA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 SER A  78
TYR A 408
ILE A  73
ASP A 105
 None
0HK  A 501 (-4.7A)
None
0HK  A 501 (-3.0A)
 1.21A 2x45C-5cxvA:
undetectable		 2x45C-5cxvA:
15.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 105
TYR A 106
SER A 109
TRP A 157
TRP A 378
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
 1.24A 3rzeA-5cxvA:
35.4		 3rzeA-5cxvA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 105
TYR A 106
SER A 109
TRP A 157
TYR A 408
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.7A)
 0.77A 3rzeA-5cxvA:
35.4		 3rzeA-5cxvA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 112
TYR A 113
SER A 116
TRP A 164
TYR A 443
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
OLC  A1208 ( 4.0A)
0HK  A1201 (-4.5A)
 0.90A 3rzeA-5dsgA:
31.2		 3rzeA-5dsgA:
48.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		5 / 12 ASP A 147
TYR A 148
ALA A 235
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 ( 3.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.43A 4dajA-4u14A:
48.5		 4dajA-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		12 / 12 ASP A 147
TYR A 148
SER A 151
ASN A 152
TRP A 199
THR A 231
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 ( 4.7A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.46A 4dajA-4u14A:
48.5		 4dajA-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 ASP A 147
TYR A 148
THR A 234
TRP A 503
ASN A 507
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
None
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-3.9A)
 1.38A 4dajA-4u14A:
48.5		 4dajA-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 105
TYR A 106
SER A 109
TRP A 157
THR A 189
ALA A 196
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.58A 4dajA-5cxvA:
43.3		 4dajA-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.22A 4dajA-5cxvA:
43.3		 4dajA-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 112
TYR A 113
SER A 116
ASN A 117
TRP A 164
THR A 196
ALA A 203
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
OLC  A1208 ( 3.6A)
OLC  A1208 ( 4.0A)
P6G  A1205 (-4.6A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.62A 4dajA-5dsgA:
42.2		 4dajA-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 112
TYR A 113
THR A 199
TRP A 413
ASN A 417
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 (-4.4A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
 1.41A 4dajA-5dsgA:
42.2		 4dajA-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TYR A 113
THR A 199
TRP A 413
TYR A 416
CYH A 442
 0HK  A1201 ( 3.2A)
OLC  A1208 (-4.4A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-3.6A)
 1.46A 4dajA-5dsgA:
42.2		 4dajA-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		12 / 12 ASP A 147
TYR A 148
SER A 151
TRP A 199
THR A 231
THR A 234
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
None
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.40A 4dajB-4u14A:
48.1		 4dajB-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 ASP A 147
TYR A 148
THR A 231
ALA A 235
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 ( 3.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.37A 4dajB-4u14A:
48.1		 4dajB-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		7 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.39A 4dajB-4u14A:
48.1		 4dajB-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		5 / 12 SER A 151
TRP A 503
TYR A 529
TYR A 533
CYH A 532
 0HK  A2000 (-3.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
None
0HK  A2000 (-3.9A)
 1.39A 4dajB-4u14A:
48.1		 4dajB-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 ASP A 105
TYR A 106
SER A 109
THR A 189
ALA A 196
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.4A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.59A 4dajB-5cxvA:
43.4		 4dajB-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.22A 4dajB-5cxvA:
43.4		 4dajB-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 105
TYR A 106
TRP A 157
THR A 189
THR A 192
ALA A 196
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.45A 4dajB-5cxvA:
43.4		 4dajB-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 112
TYR A 113
SER A 116
THR A 196
THR A 199
ALA A 203
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
P6G  A1205 (-4.6A)
OLC  A1208 (-4.4A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.64A 4dajB-5dsgA:
42.1		 4dajB-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 112
TYR A 113
THR A 196
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
P6G  A1205 (-4.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.46A 4dajB-5dsgA:
42.1		 4dajB-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 112
TYR A 113
TRP A 164
THR A 196
THR A 199
ALA A 203
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 ( 4.0A)
P6G  A1205 (-4.6A)
OLC  A1208 (-4.4A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.51A 4dajB-5dsgA:
42.1		 4dajB-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TYR A 113
THR A 196
ALA A 200
TYR A 439
CYH A 442
 0HK  A1201 ( 3.2A)
P6G  A1205 (-4.6A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.30A 4dajB-5dsgA:
42.1		 4dajB-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		12 / 12 ASP A 147
TYR A 148
SER A 151
ASN A 152
TRP A 199
THR A 231
THR A 234
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 ( 4.7A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
None
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.44A 4dajC-4u14A:
48.3		 4dajC-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		7 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.49A 4dajC-4u14A:
48.3		 4dajC-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 SER A 151
ASN A 152
TRP A 503
TYR A 529
TYR A 533
CYH A 532
 0HK  A2000 (-3.3A)
0HK  A2000 ( 4.7A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
None
0HK  A2000 (-3.9A)
 1.43A 4dajC-4u14A:
48.3		 4dajC-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 ASP A 105
TYR A 106
SER A 109
THR A 189
THR A 192
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.66A 4dajC-5cxvA:
43.1		 4dajC-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.19A 4dajC-5cxvA:
43.1		 4dajC-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 ASP A 105
TYR A 106
TRP A 157
THR A 189
THR A 192
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.54A 4dajC-5cxvA:
43.1		 4dajC-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 112
TYR A 113
ASN A 117
TRP A 164
THR A 196
THR A 199
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 ( 3.6A)
OLC  A1208 ( 4.0A)
P6G  A1205 (-4.6A)
OLC  A1208 (-4.4A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.55A 4dajC-5dsgA:
41.9		 4dajC-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 112
TYR A 113
SER A 116
ASN A 117
THR A 196
THR A 199
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
OLC  A1208 ( 3.6A)
P6G  A1205 (-4.6A)
OLC  A1208 (-4.4A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.67A 4dajC-5dsgA:
41.9		 4dajC-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 112
TYR A 113
THR A 199
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 (-4.4A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.39A 4dajC-5dsgA:
41.9		 4dajC-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		12 / 12 ASP A 147
TYR A 148
SER A 151
ASN A 152
TRP A 199
THR A 231
THR A 234
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 ( 4.7A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
None
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.43A 4dajD-4u14A:
48.9		 4dajD-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		7 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.47A 4dajD-4u14A:
48.9		 4dajD-4u14A:
95.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 105
TYR A 106
SER A 109
TRP A 157
THR A 189
THR A 192
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.61A 4dajD-5cxvA:
43.0		 4dajD-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.22A 4dajD-5cxvA:
43.0		 4dajD-5cxvA:
74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 112
TYR A 113
SER A 116
ASN A 117
TRP A 164
THR A 196
THR A 199
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
OLC  A1208 ( 3.6A)
OLC  A1208 ( 4.0A)
P6G  A1205 (-4.6A)
OLC  A1208 (-4.4A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.57A 4dajD-5dsgA:
42.1		 4dajD-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 112
TYR A 113
THR A 196
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
P6G  A1205 (-4.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.49A 4dajD-5dsgA:
42.1		 4dajD-5dsgA:
66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 105
TYR A 106
THR A 192
ALA A 196
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.28A 4u14A-5cxvA:
42.6		 4u14A-5cxvA:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ILE A  74
ASP A 105
TYR A 106
SER A 109
THR A 189
ALA A 193
ALA A 196
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 None
0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.4A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.64A 4u14A-5cxvA:
42.6		 4u14A-5cxvA:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 ILE A  74
ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 None
0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.25A 4u14A-5cxvA:
42.6		 4u14A-5cxvA:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ILE A  74
ASP A 105
TYR A 106
TRP A 157
THR A 189
ALA A 193
ALA A 196
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 None
0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.55A 4u14A-5cxvA:
42.6		 4u14A-5cxvA:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 112
TYR A 113
THR A 199
ALA A 203
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 (-4.4A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.38A 4u14A-5dsgA:
41.2		 4u14A-5dsgA:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ILE A  81
ASP A 112
TYR A 113
SER A 116
THR A 196
ALA A 200
ALA A 203
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 None
0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
P6G  A1205 (-4.6A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.71A 4u14A-5dsgA:
41.2		 4u14A-5dsgA:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 ILE A  81
ASP A 112
TYR A 113
THR A 199
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 None
0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 (-4.4A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.45A 4u14A-5dsgA:
41.2		 4u14A-5dsgA:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ILE A  81
ASP A 112
TYR A 113
TRP A 164
THR A 196
ALA A 200
ALA A 203
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 None
0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 ( 4.0A)
P6G  A1205 (-4.6A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.64A 4u14A-5dsgA:
41.2		 4u14A-5dsgA:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 4 ASN A 117
LEU A 190
PHE A 204
TYR A 416
 OLC  A1208 ( 3.6A)
P6G  A1205 (-4.6A)
None
0HK  A1201 (-4.2A)
 0.31A 4u14A-5dsgA:
41.2		 4u14A-5dsgA:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		11 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
THR A 234
ALA A 235
ALA A 238
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 (-4.3A)
None
0HK  A2000 ( 3.9A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.58A 4u15A-4u14A:
40.3		 4u15A-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 ASP A 147
TYR A 148
THR A 231
ALA A 235
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 ( 3.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.27A 4u15A-4u14A:
40.3		 4u15A-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		7 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.39A 4u15A-4u14A:
40.3		 4u15A-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		5 / 12 ASP A 147
TYR A 148
THR A 234
ALA A 238
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
None
0HK  A2000 ( 3.8A)
0HK  A2000 (-3.9A)
 1.42A 4u15A-4u14A:
40.3		 4u15A-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		11 / 12 ASP A 147
TYR A 148
TRP A 199
THR A 231
THR A 234
ALA A 235
ALA A 238
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
None
0HK  A2000 ( 3.9A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.36A 4u15A-4u14A:
40.3		 4u15A-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
SER A 109
THR A 189
TRP A 378
ASN A 382
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.7A)
 1.47A 4u15A-5cxvA:
40.5		 4u15A-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 105
TYR A 106
SER A 109
TRP A 157
THR A 189
THR A 192
ALA A 193
ALA A 196
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.50A 4u15A-5cxvA:
40.5		 4u15A-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 105
TYR A 106
THR A 189
ALA A 193
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.4A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.7A)
 1.24A 4u15A-5cxvA:
40.5		 4u15A-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.24A 4u15A-5cxvA:
40.5		 4u15A-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TYR A 106
THR A 192
ALA A 196
TYR A 404
CYH A 407
 0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.22A 4u15A-5cxvA:
40.5		 4u15A-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 112
TYR A 113
ALA A 203
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.43A 4u15A-5dsgA:
43.6		 4u15A-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 112
TYR A 113
SER A 116
TRP A 164
THR A 196
THR A 199
ALA A 200
ALA A 203
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
OLC  A1208 ( 4.0A)
P6G  A1205 (-4.6A)
OLC  A1208 (-4.4A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.44A 4u15A-5dsgA:
43.6		 4u15A-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 112
TYR A 113
THR A 196
TRP A 413
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
P6G  A1205 (-4.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.43A 4u15A-5dsgA:
43.6		 4u15A-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 112
TYR A 113
THR A 199
ALA A 203
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 (-4.4A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.44A 4u15A-5dsgA:
43.6		 4u15A-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TYR A 113
THR A 196
ALA A 200
TYR A 439
CYH A 442
 0HK  A1201 ( 3.2A)
P6G  A1205 (-4.6A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.25A 4u15A-5dsgA:
43.6		 4u15A-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TYR A 113
TRP A 164
TRP A 413
TYR A 416
CYH A 442
 0HK  A1201 ( 3.2A)
OLC  A1208 ( 4.0A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-3.6A)
 1.50A 4u15A-5dsgA:
43.6		 4u15A-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		3 / 3 ASN A 152
PHE A 239
TYR A 506
 0HK  A2000 ( 4.7A)
None
0HK  A2000 (-4.1A)
 0.14A 4u15A-4u14A:
40.4		 4u15A-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 ASN A 117
PHE A 204
TYR A 416
 OLC  A1208 ( 3.6A)
None
0HK  A1201 (-4.2A)
 0.11A 4u15A-5dsgA:
43.6		 4u15A-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		12 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
THR A 234
ALA A 235
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 (-4.3A)
None
0HK  A2000 ( 3.9A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.35A 4u15B-4u14A:
40.9		 4u15B-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		8 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.36A 4u15B-4u14A:
40.9		 4u15B-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 ASP A 147
TYR A 148
THR A 231
ALA A 235
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 ( 3.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.33A 4u15B-4u14A:
40.9		 4u15B-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 ASP A 147
TYR A 148
THR A 234
ALA A 238
TRP A 503
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
None
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-3.9A)
 1.35A 4u15B-4u14A:
40.9		 4u15B-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 105
TYR A 106
SER A 109
THR A 189
THR A 192
ALA A 193
ALA A 196
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.47A 4u15B-5cxvA:
41.1		 4u15B-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 105
TYR A 106
THR A 189
ALA A 193
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.4A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.7A)
 1.30A 4u15B-5cxvA:
41.1		 4u15B-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 105
TYR A 106
THR A 192
ALA A 196
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.27A 4u15B-5cxvA:
41.1		 4u15B-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.19A 4u15B-5cxvA:
41.1		 4u15B-5cxvA:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 112
TYR A 113
SER A 116
THR A 196
THR A 199
ALA A 200
ALA A 203
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
P6G  A1205 (-4.6A)
OLC  A1208 (-4.4A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.48A 4u15B-5dsgA:
44.9		 4u15B-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 112
TYR A 113
THR A 199
ALA A 203
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
OLC  A1208 (-4.4A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.38A 4u15B-5dsgA:
44.9		 4u15B-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TYR A 113
THR A 196
ALA A 200
TYR A 439
CYH A 442
 0HK  A1201 ( 3.2A)
P6G  A1205 (-4.6A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.27A 4u15B-5dsgA:
44.9		 4u15B-5dsgA:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		4 / 4 ASN A 152
TRP A 199
LEU A 225
PHE A 239
 0HK  A2000 ( 4.7A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.5A)
None
 0.30A 4u15B-4u14A:
40.9		 4u15B-4u14A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		5 / 12 ASP A 147
TYR A 148
ALA A 235
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 ( 3.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.31A 5cxvA-4u14A:
42.6		 5cxvA-4u14A:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		10 / 12 ASP A 147
TYR A 148
SER A 151
ALA A 235
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 ( 3.9A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.61A 5cxvA-4u14A:
42.6		 5cxvA-4u14A:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		10 / 12 ASP A 147
TYR A 148
TRP A 199
ALA A 235
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.5A)
0HK  A2000 ( 3.9A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.47A 5cxvA-4u14A:
42.6		 5cxvA-4u14A:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 112
TYR A 113
ALA A 203
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 1.37A 5cxvA-5dsgA:
42.1		 5cxvA-5dsgA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 112
TYR A 113
SER A 116
TRP A 164
ALA A 200
ALA A 203
TRP A 413
TYR A 416
ASN A 417
TYR A 439
CYH A 442
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
OLC  A1208 ( 4.0A)
0HK  A1201 ( 4.2A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
0HK  A1201 (-4.2A)
0HK  A1201 (-2.8A)
0HK  A1201 (-3.6A)
0HK  A1201 (-3.6A)
 0.38A 5cxvA-5dsgA:
42.1		 5cxvA-5dsgA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		3 / 3 THR A 231
THR A 234
PHE A 239
 0HK  A2000 (-4.3A)
None
None
 0.52A 5cxvA-4u14A:
42.6		 5cxvA-4u14A:
73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		11 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
THR A 234
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 (-4.3A)
None
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.63A 5dsgA-4u14A:
41.2		 5dsgA-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 ASP A 147
TYR A 148
THR A 231
ALA A 235
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 ( 3.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.38A 5dsgA-4u14A:
41.2		 5dsgA-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		7 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.42A 5dsgA-4u14A:
41.2		 5dsgA-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		11 / 12 ASP A 147
TYR A 148
TRP A 199
THR A 231
THR A 234
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-3.2A)
0HK  A2000 (-2.8A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
None
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.51A 5dsgA-4u14A:
41.2		 5dsgA-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 105
TYR A 106
ALA A 193
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.37A 5dsgA-5cxvA:
42.1		 5dsgA-5cxvA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 105
TYR A 106
SER A 109
TRP A 157
THR A 189
THR A 192
ALA A 196
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.44A 5dsgA-5cxvA:
42.1		 5dsgA-5cxvA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 105
TYR A 106
THR A 189
ALA A 193
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.4A)
0HK  A 501 (-3.9A)
0HK  A 501 (-3.7A)
 1.34A 5dsgA-5cxvA:
42.1		 5dsgA-5cxvA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 105
TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.25A 5dsgA-5cxvA:
42.1		 5dsgA-5cxvA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		5 / 12 LEU A 144
TRP A 503
TYR A 529
TYR A 533
CYH A 532
 None
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
None
0HK  A2000 (-3.9A)
 1.46A 5dsgB-4u14A:
37.8		 5dsgB-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		10 / 12 TYR A 148
SER A 151
LEU A 225
THR A 231
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-2.8A)
0HK  A2000 (-3.3A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.59A 5dsgB-4u14A:
37.8		 5dsgB-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		5 / 12 TYR A 148
THR A 231
ALA A 235
TYR A 529
CYH A 532
 0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 ( 3.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.31A 5dsgB-4u14A:
37.8		 5dsgB-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		6 / 12 TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-2.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.3A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 1.49A 5dsgB-4u14A:
37.8		 5dsgB-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		11 / 12 TYR A 148
TRP A 199
LEU A 225
THR A 231
THR A 234
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
 0HK  A2000 (-2.8A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.5A)
0HK  A2000 (-4.3A)
None
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
0HK  A2000 (-4.1A)
0HK  A2000 (-2.9A)
0HK  A2000 (-4.1A)
0HK  A2000 (-3.9A)
 0.44A 5dsgB-4u14A:
37.8		 5dsgB-4u14A:
67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 TYR A 106
SER A 109
TRP A 157
LEU A 183
THR A 189
THR A 192
ALA A 196
TRP A 378
TYR A 381
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
None
0HK  A 501 (-4.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-3.6A)
0HK  A 501 (-4.4A)
0HK  A 501 (-4.1A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 0.38A 5dsgB-5cxvA:
40.4		 5dsgB-5cxvA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TYR A 106
THR A 192
TRP A 378
ASN A 382
TYR A 404
CYH A 407
 0HK  A 501 (-3.4A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
0HK  A 501 (-2.8A)
0HK  A 501 (-3.6A)
0HK  A 501 (-3.7A)
 1.28A 5dsgB-5cxvA:
40.4		 5dsgB-5cxvA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Escherichia
virus
T4;
Rattus
norvegicus) 		3 / 3 ASP A 147
ASN A 152
PHE A 239
 0HK  A2000 (-3.2A)
0HK  A2000 ( 4.7A)
None
 0.59A 5dsgB-4u14A:
37.8		 5dsgB-4u14A:
67.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Rattus
norvegicus;
Escherichia
virus
T4) 		3 / 3 LEU A 144
TYR A 529
SER A 120
 None
0HK  A2000 (-4.1A)
None
 0.76A 5iktA-4u14A:
0.2		 5iktA-4u14A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3
(Rattus
norvegicus;
Escherichia
virus
T4) 		5 / 12 TRP A 143
LEU A 144
SER A 151
ALA A 238
TRP A 503
 None
None
0HK  A2000 (-3.3A)
0HK  A2000 ( 3.8A)
0HK  A2000 (-4.3A)
 1.49A 6drxA-4u14A:
27.3		 6drxA-4u14A:
28.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 TRP A 108
LEU A 109
SER A 116
ALA A 203
TRP A 413
 None
P6G  A1205 (-4.7A)
0HK  A1201 (-3.3A)
0HK  A1201 (-3.6A)
0HK  A1201 (-4.3A)
 1.22A 6drxA-5dsgA:
27.4		 6drxA-5dsgA:
29.55