SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0GJ'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1AQ7_B_AG2B4_1 (TRYPSINAERUGINOSIN 98-B) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 6 / 8 | HIS A 57ASP A 189GLN A 192SER A 195GLY A 216GLY A 226 | 0GJ A 245 (-2.7A)0GJ A 245 (-3.1A)0GJ A 245 (-3.5A)0GJ A 245 (-1.4A)0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.70A | 1aq7A-1a5iA:31.5 | 1aq7A-1a5iA:37.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1AQ7_B_AG2B4_1 (TRYPSINAERUGINOSIN 98-B) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 6 / 8 | HIS A 57ASP A 189SER A 195VAL A 213GLY A 216GLY A 226 | 0GJ A 1 ( 2.7A)0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.64A | 1aq7A-1bqyA:34.7 | 1aq7A-1bqyA:42.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AQ7_B_AG2B4_1 (TRYPSINAERUGINOSIN 98-B) |
4bxw | FACTOR XA (Pseudonajatextilis) | 7 / 8 | HIS A 211ASP A 356GLN A 359SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.8A)0GJ A1411 (-2.7A)0GJ A1411 (-3.6A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.70A | 1aq7A-4bxwA:33.0 | 1aq7A-4bxwA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AV2_A_DVAA6_0 (GRAMICIDIN A) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | ALA A 55VAL A 99TRP A 215 | None0GJ A 1 ( 4.2A)None | 0.83A | 1av2A-1bqyA:undetectable1av2B-1bqyA:undetectable | 1av2A-1bqyA:7.011av2B-1bqyA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AV2_D_DVAD6_0 (GRAMICIDIN A) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | TRP A 215ALA A 55VAL A 99 | NoneNone0GJ A 1 ( 4.2A) | 0.77A | 1av2C-1bqyA:undetectable1av2D-1bqyA:undetectable | 1av2C-1bqyA:7.011av2D-1bqyA:7.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1BCU_H_PRLH280_0 (ALPHA-THROMBIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 6 / 9 | ASP A 189ALA A 190SER A 195TRP A 215GLY A 216GLY A 226 | 0GJ A 245 (-3.1A)0GJ A 245 (-3.4A)0GJ A 245 (-1.4A)None0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.31A | 1bcuH-1a5iA:16.5 | 1bcuH-1a5iA:32.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1BCU_H_PRLH280_0 (ALPHA-THROMBIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 6 / 9 | ASP A 189SER A 195VAL A 213TRP A 215GLY A 216GLY A 226 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)NoneNone0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.33A | 1bcuH-1bqyA:17.3 | 1bcuH-1bqyA:33.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1BCU_H_PRLH280_0 (ALPHA-THROMBIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 6 / 9 | ASP A 356ALA A 357SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.7A)0GJ A1411 (-3.4A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.37A | 1bcuH-4bxwA:34.2 | 1bcuH-4bxwA:25.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DWC_H_MITH1_1 (ALPHA-THROMBIN(LARGE SUBUNIT)) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 5 / 9 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 226 | 0GJ A 245 (-2.7A)0GJ A 245 (-3.1A)0GJ A 245 (-1.4A)None0GJ A 245 ( 4.2A) | 0.48A | 1dwcH-1a5iA:33.2 | 1dwcH-1a5iA:32.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DWC_H_MITH1_1 (ALPHA-THROMBIN(LARGE SUBUNIT)) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 9 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 226 | 0GJ A 1 ( 2.7A)0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 ( 4.3A) | 0.35A | 1dwcH-1bqyA:32.2 | 1dwcH-1bqyA:33.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETR_H_MITH1_1 (EPSILON-THROMBIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 6 / 12 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 216GLY A 226 | 0GJ A 245 (-2.7A)0GJ A 245 (-3.1A)0GJ A 245 (-1.4A)None0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.68A | 1etrH-1a5iA:32.8 | 1etrH-1a5iA:33.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETR_H_MITH1_1 (EPSILON-THROMBIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 7 / 12 | HIS A 57ASP A 189SER A 195VAL A 213TRP A 215GLY A 216GLY A 226 | 0GJ A 1 ( 2.7A)0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)NoneNone0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.61A | 1etrH-1bqyA:32.2 | 1etrH-1bqyA:32.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETR_H_MITH1_1 (EPSILON-THROMBIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 6 / 12 | HIS A 211ASP A 356SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.8A)0GJ A1411 (-2.7A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.69A | 1etrH-4bxwA:32.9 | 1etrH-4bxwA:38.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1F5L_A_AMRA301_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 8 | ASP A 189SER A 195GLY A 216GLY A 226 | 0GJ A 245 (-3.1A)0GJ A 245 (-1.4A)0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.37A | 1f5lA-1a5iA:35.8 | 1f5lA-1a5iA:39.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1F5L_A_AMRA301_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 8 | ASP A 189SER A 195VAL A 213GLY A 216GLY A 226 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.44A | 1f5lA-1bqyA:32.6 | 1f5lA-1bqyA:32.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1F5L_A_AMRA301_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 8 | ASP A 356SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.7A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.39A | 1f5lA-4bxwA:31.7 | 1f5lA-4bxwA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 10 | SER A 362SER A 381ILE A 379GLY A 378GLY A 393 | 0GJ A1411 (-1.4A)NoneNoneNone0GJ A1411 (-3.3A) | 1.24A | 1mehA-4bxwA:undetectable | 1mehA-4bxwA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MXD_A_ACRA732_1 (ALPHA AMYLASE) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 9 | GLY A 184GLU A 224GLY A 223GLY A 216GLY A 217 | NoneNoneNone0GJ A 1 (-3.5A)0GJ A 1 (-4.1A) | 1.07A | 1mxdA-1bqyA:0.0 | 1mxdA-1bqyA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MXG_A_ACRA442_1 (ALPHA AMYLASE) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 11 | GLY A 184GLU A 224GLY A 223GLY A 216GLY A 217 | NoneNoneNone0GJ A 1 (-3.5A)0GJ A 1 (-4.1A) | 1.03A | 1mxgA-1bqyA:undetectable | 1mxgA-1bqyA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RQP_B_SAMB500_1 (5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE) |
4bxw | FACTOR XA (Pseudonajatextilis) | 4 / 8 | ASP A 265PHE A 248SER A 362ALA A 267 | NoneNone0GJ A1411 (-1.4A)None | 1.09A | 1rqpC-4bxwA:undetectable | 1rqpC-4bxwA:21.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TNL_A_TPAA900_1 (TRYPSIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 6 | ASP A 189SER A 195GLY A 216GLY A 226 | 0GJ A 245 (-3.1A)0GJ A 245 (-1.4A)0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.38A | 1tnlA-1a5iA:31.4 | 1tnlA-1a5iA:36.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TNL_A_TPAA900_1 (TRYPSIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 6 | ASP A 189SER A 195VAL A 213GLY A 216GLY A 226 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.40A | 1tnlA-1bqyA:35.5 | 1tnlA-1bqyA:42.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1TNL_A_TPAA900_1 (TRYPSIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 6 | ASP A 356SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.7A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.34A | 1tnlA-4bxwA:32.8 | 1tnlA-4bxwA:25.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W5U_A_DVAA6_0 (GRAMICIDIN D) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | ALA A 55VAL A 99TRP A 215 | None0GJ A 1 ( 4.2A)None | 0.80A | 1w5uA-1bqyA:undetectable1w5uB-1bqyA:undetectable | 1w5uA-1bqyA:7.011w5uB-1bqyA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W5U_B_DVAB6_0 (GRAMICIDIN D) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | TRP A 215ALA A 55VAL A 99 | NoneNone0GJ A 1 ( 4.2A) | 0.76A | 1w5uA-1bqyA:undetectable1w5uB-1bqyA:undetectable | 1w5uA-1bqyA:7.011w5uB-1bqyA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2IZQ_A_DVAA6_0 (GRAMICIDIN D) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | ALA A 55VAL A 99TRP A 215 | None0GJ A 1 ( 4.2A)None | 0.76A | 2izqA-1bqyA:undetectable2izqB-1bqyA:undetectable | 2izqA-1bqyA:7.012izqB-1bqyA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2IZQ_D_DVAD6_0 (GRAMICIDIN D) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | TRP A 215ALA A 55VAL A 99 | NoneNone0GJ A 1 ( 4.2A) | 0.87A | 2izqC-1bqyA:undetectable2izqD-1bqyA:undetectable | 2izqC-1bqyA:7.012izqD-1bqyA:7.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 6 | ASP A 189SER A 195GLY A 216GLY A 226 | 0GJ A 245 (-3.1A)0GJ A 245 (-1.4A)0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.32A | 2otvA-1a5iA:11.7 | 2otvA-1a5iA:37.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 6 | ASP A 189SER A 195VAL A 213GLY A 216GLY A 226 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.29A | 2otvA-1bqyA:35.8 | 2otvA-1bqyA:42.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 6 | ASP A 356SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.7A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.21A | 2otvA-4bxwA:33.0 | 2otvA-4bxwA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OXT_D_SAMD300_0 (NUCLEOSIDE-2'-O-METHYLTRANSFERASE) |
4bxw | FACTOR XA (Pseudonajatextilis) | 6 / 12 | GLY A 308GLY A 198GLY A 363GLY A 360THR A 208LEU A 207 | NoneNoneNone0GJ A1411 (-3.8A)NoneNone | 1.45A | 2oxtD-4bxwA:undetectable | 2oxtD-4bxwA:19.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2P16_A_GG2A298_1 (COAGULATION FACTOR X(EC 3.4.21.6)(STUART FACTOR)(STUART-PROWERFACTOR)) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 8 / 12 | TYR A 99ASP A 189ALA A 190SER A 195TRP A 215GLY A 216GLY A 226TYR A 228 | 0GJ A 245 (-3.9A)0GJ A 245 (-3.1A)0GJ A 245 (-3.4A)0GJ A 245 (-1.4A)None0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A)None | 0.44A | 2p16A-1a5iA:32.5 | 2p16A-1a5iA:35.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2P16_A_GG2A298_1 (COAGULATION FACTOR X(EC 3.4.21.6)(STUART FACTOR)(STUART-PROWERFACTOR)) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 7 / 12 | ASP A 189SER A 195VAL A 213TRP A 215GLY A 216GLY A 226TYR A 228 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)NoneNone0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A)None | 0.37A | 2p16A-1bqyA:13.0 | 2p16A-1bqyA:28.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2P16_A_GG2A298_1 (COAGULATION FACTOR X(EC 3.4.21.6)(STUART FACTOR)(STUART-PROWERFACTOR)) |
4bxw | FACTOR XA (Pseudonajatextilis) | 8 / 12 | TYR A 262ASP A 356ALA A 357SER A 362VAL A 380GLY A 383GLY A 393TYR A 395 | 0GJ A1411 ( 3.5A)0GJ A1411 (-2.7A)0GJ A1411 (-3.4A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A)None | 0.42A | 2p16A-4bxwA:38.9 | 2p16A-4bxwA:55.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VIN_A_505A1247_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR CHAIN B) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 8 | ASP A 189SER A 195GLY A 216GLY A 226 | 0GJ A 245 (-3.1A)0GJ A 245 (-1.4A)0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.43A | 2vinA-1a5iA:36.3 | 2vinA-1a5iA:39.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VIN_A_505A1247_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR CHAIN B) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 8 | ASP A 189SER A 195VAL A 213GLY A 216GLY A 226 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.48A | 2vinA-1bqyA:10.1 | 2vinA-1bqyA:32.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2VIN_A_505A1247_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR CHAIN B) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 8 | ASP A 356SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.7A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.40A | 2vinA-4bxwA:9.5 | 2vinA-4bxwA:22.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2W26_A_RIVA1001_1 (ACTIVATED FACTOR XAHEAVY CHAIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 9 / 12 | TYR A 99ASP A 189ALA A 190SER A 195TRP A 215GLY A 216GLY A 219GLY A 226TYR A 228 | 0GJ A 245 (-3.9A)0GJ A 245 (-3.1A)0GJ A 245 (-3.4A)0GJ A 245 (-1.4A)None0GJ A 245 (-3.5A)0GJ A 245 (-3.8A)0GJ A 245 ( 4.2A)None | 0.47A | 2w26A-1a5iA:32.5 | 2w26A-1a5iA:35.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2W26_A_RIVA1001_1 (ACTIVATED FACTOR XAHEAVY CHAIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 7 / 12 | ASP A 189SER A 195VAL A 213TRP A 215GLY A 216GLY A 217TYR A 228 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)NoneNone0GJ A 1 (-3.5A)0GJ A 1 (-4.1A)None | 0.86A | 2w26A-1bqyA:11.8 | 2w26A-1bqyA:28.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2W26_A_RIVA1001_1 (ACTIVATED FACTOR XAHEAVY CHAIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 7 / 12 | ASP A 189SER A 195VAL A 213TRP A 215GLY A 216GLY A 226TYR A 228 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)NoneNone0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A)None | 0.33A | 2w26A-1bqyA:11.8 | 2w26A-1bqyA:28.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2W26_A_RIVA1001_1 (ACTIVATED FACTOR XAHEAVY CHAIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 9 / 12 | TYR A 262ASP A 356ALA A 357SER A 362VAL A 380GLY A 383GLY A 385GLY A 393TYR A 395 | 0GJ A1411 ( 3.5A)0GJ A1411 (-2.7A)0GJ A1411 (-3.4A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)None0GJ A1411 (-3.3A)None | 0.39A | 2w26A-4bxwA:38.8 | 2w26A-4bxwA:55.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CLA_A_CLMA221_0 (TYPE IIICHLORAMPHENICOLACETYLTRANSFERASE) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 5 / 9 | ALA A 190SER A 139LEU A 209VAL A 231ILE A 45 | 0GJ A 245 (-3.4A)NoneNoneNoneNone | 1.39A | 3claA-1a5iA:0.0 | 3claA-1a5iA:19.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GY3_A_PNTA246_0 (CATIONIC TRYPSIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 7 / 11 | HIS A 57ASP A 189GLN A 192SER A 195TRP A 215GLY A 216GLY A 226 | 0GJ A 245 (-2.7A)0GJ A 245 (-3.1A)0GJ A 245 (-3.5A)0GJ A 245 (-1.4A)None0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.57A | 3gy3A-1a5iA:11.4 | 3gy3A-1a5iA:37.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GY3_A_PNTA246_0 (CATIONIC TRYPSIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 6 / 11 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 216GLY A 226 | 0GJ A 1 ( 2.7A)0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.48A | 3gy3A-1bqyA:34.1 | 3gy3A-1bqyA:42.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3GY3_A_PNTA246_0 (CATIONIC TRYPSIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 6 / 11 | HIS A 211ASP A 356GLN A 359SER A 362GLY A 383GLY A 393 | 0GJ A1411 (-2.8A)0GJ A1411 (-2.7A)0GJ A1411 (-3.6A)0GJ A1411 (-1.4A)0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.62A | 3gy3A-4bxwA:32.7 | 3gy3A-4bxwA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK6_B_HCZB800_1 (GLUTAMATE RECEPTOR 2) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 5 / 10 | LEU A 209ILE A 45SER A 195SER A 214GLY A 196 | NoneNone0GJ A 245 (-1.4A)NoneNone | 1.33A | 3ik6B-1a5iA:undetectable3ik6E-1a5iA:undetectable | 3ik6B-1a5iA:20.793ik6E-1a5iA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3L8L_B_DVAB6_0 (GRAMICIDIN D) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | TRP A 215ALA A 55VAL A 99 | NoneNone0GJ A 1 ( 4.2A) | 1.01A | 3l8lA-1bqyA:undetectable3l8lB-1bqyA:undetectable | 3l8lA-1bqyA:7.013l8lB-1bqyA:8.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3L8L_D_DVAD6_0 (GRAMICIDIN D) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 3 / 3 | TRP A 215ALA A 55VAL A 99 | NoneNone0GJ A 1 ( 4.2A) | 0.87A | 3l8lC-1bqyA:undetectable3l8lD-1bqyA:undetectable | 3l8lC-1bqyA:7.013l8lD-1bqyA:8.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RXF_A_4APA9_1 (CATIONIC TRYPSIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 6 | SER A 195TRP A 215GLY A 216GLY A 226 | 0GJ A 245 (-1.4A)None0GJ A 245 (-3.5A)0GJ A 245 ( 4.2A) | 0.35A | 3rxfA-1a5iA:11.4 | 3rxfA-1a5iA:37.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RXF_A_4APA9_1 (CATIONIC TRYPSIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 6 | SER A 195VAL A 213TRP A 215GLY A 216GLY A 226 | 0GJ A 1 ( 1.4A)NoneNone0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.30A | 3rxfA-1bqyA:15.3 | 3rxfA-1bqyA:42.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3RXF_A_4APA9_1 (CATIONIC TRYPSIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 4 / 6 | SER A 362VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-1.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.34A | 3rxfA-4bxwA:13.5 | 3rxfA-4bxwA:23.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RXH_A_HSMA7_1 (CATIONIC TRYPSIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 4 / 5 | ASP A 189SER A 195VAL A 213GLY A 226 | 0GJ A 1 (-3.1A)0GJ A 1 ( 1.4A)None0GJ A 1 ( 4.3A) | 0.41A | 3rxhA-1bqyA:35.4 | 3rxhA-1bqyA:42.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3RXH_A_HSMA7_1 (CATIONIC TRYPSIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 4 / 5 | ASP A 356SER A 362VAL A 380GLY A 393 | 0GJ A1411 (-2.7A)0GJ A1411 (-1.4A)None0GJ A1411 (-3.3A) | 0.39A | 3rxhA-4bxwA:33.0 | 3rxhA-4bxwA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3S43_A_478A401_1 (PROTEASE) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 9 | ALA A 183ILE A 138VAL A 213GLY A 216ILE A 160 | NoneNoneNone0GJ A 1 (-3.5A)None | 0.99A | 3s43A-1bqyA:undetectable | 3s43A-1bqyA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3T01_A_PPFA503_1 (PHOSPHONOACETATEHYDROLASE) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 7 | THR A 229ASP A 102HIS A 57ILE A 213 | NoneNone0GJ A 245 (-2.7A)None | 0.98A | 3t01A-1a5iA:undetectable | 3t01A-1a5iA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TNE_B_RITB401_2 (SECRETED ASPARTICPROTEASE) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 4 / 7 | SER A 195THR A 229THR A 180TYR A 234 | 0GJ A 1 ( 1.4A)NoneNoneNone | 0.80A | 3tneB-1bqyA:undetectable | 3tneB-1bqyA:21.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FU8_A_ACTA302_0 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 5 | HIS A 57GLN A 192GLY A 193SER A 195 | 0GJ A 245 (-2.7A)0GJ A 245 (-3.5A)0GJ A 245 (-3.7A)0GJ A 245 (-1.4A) | 0.86A | 4fu8A-1a5iA:35.9 | 4fu8A-1a5iA:40.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FU8_A_ACTA302_0 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 5 | HIS A 57TYR A 151GLY A 193SER A 195 | 0GJ A 245 (-2.7A)None0GJ A 245 (-3.7A)0GJ A 245 (-1.4A) | 0.49A | 4fu8A-1a5iA:35.9 | 4fu8A-1a5iA:40.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4FU8_A_ACTA302_0 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
4bxw | FACTOR XA (Pseudonajatextilis) | 4 / 5 | HIS A 211GLN A 359GLY A 360SER A 362 | 0GJ A1411 (-2.8A)0GJ A1411 (-3.6A)0GJ A1411 (-3.8A)0GJ A1411 (-1.4A) | 0.96A | 4fu8A-4bxwA:31.9 | 4fu8A-4bxwA:21.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4HFP_D_15UD402_1 (PROTHROMBIN) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 5 / 12 | HIS A 57ASP A 189ALA A 190TRP A 215GLY A 226 | 0GJ A 245 (-2.7A)0GJ A 245 (-3.1A)0GJ A 245 (-3.4A)None0GJ A 245 ( 4.2A) | 0.31A | 4hfpD-1a5iA:32.8 | 4hfpD-1a5iA:32.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4HFP_D_15UD402_1 (PROTHROMBIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 12 | HIS A 57ASP A 189VAL A 213TRP A 215GLY A 226 | 0GJ A 1 ( 2.7A)0GJ A 1 (-3.1A)NoneNone0GJ A 1 ( 4.3A) | 0.26A | 4hfpD-1bqyA:31.9 | 4hfpD-1bqyA:32.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HFP_D_15UD402_1 (PROTHROMBIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 12 | HIS A 211ASP A 356ALA A 357VAL A 380GLY A 393 | 0GJ A1411 (-2.8A)0GJ A1411 (-2.7A)0GJ A1411 (-3.4A)None0GJ A1411 (-3.3A) | 0.27A | 4hfpD-4bxwA:33.1 | 4hfpD-4bxwA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4N48_A_SAMA601_0 (CAP-SPECIFIC MRNA(NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 12 | GLY A 364PRO A 365LEU A 187THR A 216GLY A 360 | NoneNoneNoneNone0GJ A1411 (-3.8A) | 1.27A | 4n48A-4bxwA:undetectable | 4n48A-4bxwA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN) |
1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) | 5 / 12 | HIS A 57VAL A 213TRP A 215GLY A 216GLY A 226 | 0GJ A 1 ( 2.7A)NoneNone0GJ A 1 (-3.5A)0GJ A 1 ( 4.3A) | 0.38A | 4rn6B-1bqyA:27.4 | 4rn6B-1bqyA:29.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN) |
4bxw | FACTOR XA (Pseudonajatextilis) | 5 / 12 | HIS A 211ALA A 357VAL A 380GLY A 383GLY A 393 | 0GJ A1411 (-2.8A)0GJ A1411 (-3.4A)None0GJ A1411 (-3.7A)0GJ A1411 (-3.3A) | 0.84A | 4rn6B-4bxwA:29.1 | 4rn6B-4bxwA:27.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ECL_A_ILEA602_0 (JASMONIC ACID-AMIDOSYNTHETASE JAR1) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 4 / 6 | ALA A 56VAL A 90TYR A 88HIS A 57 | NoneNoneNone0GJ A 245 (-2.7A) | 0.98A | 5eclA-1a5iA:undetectable | 5eclA-1a5iA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6C2M_C_SUEC1203_0 (NS3 PROTEASE) |
1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) | 5 / 12 | HIS A 57ASP A 102GLY A 193SER A 195VAL A 217 | 0GJ A 245 (-2.7A)None0GJ A 245 (-3.7A)0GJ A 245 (-1.4A)0GJ A 245 ( 4.9A) | 0.90A | 6c2mC-1a5iA:4.4 | 6c2mC-1a5iA:15.38 |