SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0GA'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1I7Q_A_BEZA1501_0 (ANTHRANILATESYNTHASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 6 / 11 | GLU A 307ILE A 322GLY A 324THR A 325HIS A 388LEU A 416 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)0GA A 604 ( 4.7A) | 0.67A | 1i7qA-5cwaA:41.2 | 1i7qA-5cwaA:38.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1I7Q_A_BEZA1501_0 (ANTHRANILATESYNTHASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307ILE A 322THR A 325HIS A 388GLY A 474 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)0GA A 604 ( 4.4A) | 1.00A | 1i7qA-5cwaA:41.2 | 1i7qA-5cwaA:38.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1I7Q_A_BEZA1501_0 (ANTHRANILATESYNTHASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 6 / 11 | GLU A 307ILE A 322THR A 325HIS A 388LEU A 416GLY A 475 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)0GA A 604 ( 4.7A)None | 0.79A | 1i7qA-5cwaA:41.2 | 1i7qA-5cwaA:38.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1I7Q_A_BEZA1501_0 (ANTHRANILATESYNTHASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307LEU A 416GLY A 475GLU A 488LYS A 492 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.7A)None0GA A 604 ( 4.9A)0GA A 604 (-3.0A) | 0.80A | 1i7qA-5cwaA:41.2 | 1i7qA-5cwaA:38.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1I7Q_C_BEZC1502_0 (ANTHRANILATESYNTHASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 6 / 10 | GLU A 307ILE A 322GLY A 324THR A 325HIS A 388GLY A 475 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)None | 0.68A | 1i7qC-5cwaA:41.2 | 1i7qC-5cwaA:38.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1I7Q_C_BEZC1502_0 (ANTHRANILATESYNTHASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 10 | GLU A 307ILE A 322THR A 325HIS A 388GLY A 474 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)0GA A 604 ( 4.4A) | 0.95A | 1i7qC-5cwaA:41.2 | 1i7qC-5cwaA:38.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AZQ_A_PCFA954_0 (CATECHOL1,2-DIOXYGENASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 9 | LEU A 358GLU A 307HIS A 388ALA A 323GLU A 488 | None0GA A 604 ( 4.5A)0GA A 604 ( 4.3A)None0GA A 604 ( 4.9A) | 1.40A | 2azqA-5cwaA:undetectable | 2azqA-5cwaA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FN1_A_SALA506_1 (SALICYLATESYNTHETASE, IRP9) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307GLY A 324THR A 325HIS A 388GLY A 475 | 0GA A 604 ( 4.5A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)None | 0.72A | 2fn1A-5cwaA:38.4 | 2fn1A-5cwaA:28.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FN1_B_SALB503_1 (SALICYLATESYNTHETASE, IRP9) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307GLY A 324THR A 325HIS A 388THR A 415 | 0GA A 604 ( 4.5A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)None | 0.56A | 2fn1B-5cwaA:38.1 | 2fn1B-5cwaA:28.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FN1_B_SALB503_1 (SALICYLATESYNTHETASE, IRP9) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307THR A 325HIS A 388THR A 415GLY A 474 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)None0GA A 604 ( 4.4A) | 0.95A | 2fn1B-5cwaA:38.1 | 2fn1B-5cwaA:28.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FN1_B_SALB503_1 (SALICYLATESYNTHETASE, IRP9) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307THR A 325HIS A 388THR A 415GLY A 475 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A)NoneNone | 0.54A | 2fn1B-5cwaA:38.1 | 2fn1B-5cwaA:28.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BXO_A_SAMA238_1 (N,N-DIMETHYLTRANSFERASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 3 / 3 | TYR A 439GLU A 485ASP A 479 | 0GA A 604 ( 4.4A)NoneNone | 0.84A | 3bxoA-5cwaA:undetectable | 3bxoA-5cwaA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3R75_A_BEZA701_0 (ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 12 | GLU A 307ILE A 322GLY A 324THR A 325HIS A 388 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A) | 0.27A | 3r75A-5cwaA:34.5 | 3r75A-5cwaA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3R75_B_BEZB701_0 (ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 12 | GLU A 307ILE A 322GLY A 324THR A 325HIS A 388 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A) | 0.29A | 3r75B-5cwaA:33.8 | 3r75B-5cwaA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3R76_A_BEZA701_0 (ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307ILE A 322GLY A 324THR A 325HIS A 388 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A) | 0.27A | 3r76A-5cwaA:34.8 | 3r76A-5cwaA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3R76_B_BEZB701_0 (ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 11 | GLU A 307ILE A 322GLY A 324THR A 325HIS A 388 | 0GA A 604 ( 4.5A)0GA A 604 ( 4.2A)None0GA A 604 ( 4.6A)0GA A 604 ( 4.3A) | 0.29A | 3r76B-5cwaA:33.9 | 3r76B-5cwaA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4FGK_A_0TXA302_1 (RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE[QUINONE]) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 4 / 7 | GLY A 474GLY A 473TYR A 439GLU A 485 | 0GA A 604 ( 4.4A)0GA A 604 (-3.8A)0GA A 604 ( 4.4A)None | 1.08A | 4fgkB-5cwaA:undetectable | 4fgkB-5cwaA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4YDQ_A_HFGA802_1 (PROLINE--TRNA LIGASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 4 / 4 | THR A 415GLU A 307THR A 325HIS A 388 | None0GA A 604 ( 4.5A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A) | 1.47A | 4ydqA-5cwaA:undetectable | 4ydqA-5cwaA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5F9Z_A_HFGA702_1 (AMINOACYL-TRNASYNTHETASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 4 / 4 | THR A 415GLU A 307THR A 325HIS A 388 | None0GA A 604 ( 4.5A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A) | 1.43A | 5f9zA-5cwaA:undetectable | 5f9zA-5cwaA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5F9Z_B_HFGB703_1 (AMINOACYL-TRNASYNTHETASE) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 4 / 4 | THR A 415GLU A 307THR A 325HIS A 388 | None0GA A 604 ( 4.5A)0GA A 604 ( 4.6A)0GA A 604 ( 4.3A) | 1.43A | 5f9zB-5cwaA:undetectable | 5f9zB-5cwaA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6AWO_A_SREA701_1 (SODIUM-DEPENDENTSEROTONINTRANSPORTER) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 9 | ALA A 457ILE A 456GLY A 474SER A 417GLY A 440 | NoneNone0GA A 604 ( 4.4A)NoneNone | 1.29A | 6awoA-5cwaA:undetectable | 6awoA-5cwaA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6AWQ_A_SREA701_1 (SODIUM-DEPENDENTSEROTONINTRANSPORTER) |
5cwa | ANTHRANILATESYNTHASE COMPONENT 1 (Mycobacteriumtuberculosis) | 5 / 9 | ALA A 457ILE A 456GLY A 474SER A 417GLY A 440 | NoneNone0GA A 604 ( 4.4A)NoneNone | 1.29A | 6awqA-5cwaA:undetectable | 6awqA-5cwaA:20.79 |