SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0FG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 8 SER C 190
SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.64A 1aq7A-1afqC:
9.3		 1aq7A-1afqC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 9 SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
 0FG  C 301 ( 3.0A)
None
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.26A 1bcuH-1afqC:
9.7		 1bcuH-1afqC:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 12 SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
 0FG  C 301 ( 3.0A)
None
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.43A 1etrH-1afqC:
8.5		 1etrH-1afqC:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 8 SER C 190
SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.57A 1f5lA-1afqC:
12.5		 1f5lA-1afqC:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TNL_A_TPAA900_1
(TRYPSIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 6 SER C 190
SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.54A 1tnlA-1afqC:
11.3		 1tnlA-1afqC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 6 SER C 190
SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.51A 2otvA-1afqC:
11.5		 2otvA-1afqC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		6 / 12 SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
TYR C 228
 0FG  C 301 ( 3.0A)
None
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
None
 0.35A 2p16A-1afqC:
12.6		 2p16A-1afqC:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 8 SER C 190
SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.57A 2vinA-1afqC:
11.1		 2vinA-1afqC:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		6 / 12 SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
TYR C 228
 0FG  C 301 ( 3.0A)
None
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
None
 0.31A 2w26A-1afqC:
11.0		 2w26A-1afqC:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		5 / 11 SER C 190
SER C 195
TRP C 215
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.58A 3gy3A-1afqC:
11.2		 3gy3A-1afqC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		6 / 6 SER C 190
SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.61A 3rxfA-1afqC:
9.4		 3rxfA-1afqC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		4 / 5 SER C 190
SER C 195
VAL C 213
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 ( 4.4A)
 0.67A 3rxhA-1afqC:
11.5		 3rxhA-1afqC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1afq BOVINE
GAMMA-CHYMOTRYPSIN
(Bos
taurus) 		4 / 4 LEU C 160
GLY C 184
SER C 189
SER C 190
 None
None
0FG  C 301 (-3.6A)
None
 0.97A 5uunA-1afqC:
undetectable		 5uunA-1afqC:
15.30