SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '0EJ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 4nzm INOSITOL
HEXAKISPHOSPHATE AND
DIPHOSPHOINOSITOL-PE
NTAKISPHOSPHATE
KINASE 2
(Homo
sapiens) 		4 / 7 ARG A 262
ASP A 309
ASP A 321
TYR A 250
 0EJ  A 402 (-3.0A)
MG  A 404 ( 2.9A)
MG  A 403 (-2.0A)
None
 1.15A 1ceaB-4nzmA:
undetectable		 1ceaB-4nzmA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 4nzm INOSITOL
HEXAKISPHOSPHATE AND
DIPHOSPHOINOSITOL-PE
NTAKISPHOSPHATE
KINASE 2
(Homo
sapiens) 		4 / 7 ARG A 262
ASP A 309
ASP A 321
TYR A 250
 0EJ  A 402 (-3.0A)
MG  A 404 ( 2.9A)
MG  A 403 (-2.0A)
None
 1.11A 1cebA-4nzmA:
undetectable		 1cebA-4nzmA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4nzm INOSITOL
HEXAKISPHOSPHATE AND
DIPHOSPHOINOSITOL-PE
NTAKISPHOSPHATE
KINASE 2
(Homo
sapiens) 		3 / 3 TYR A 250
ARG A 262
LYS A 248
 None
0EJ  A 402 (-3.0A)
0EJ  A 402 ( 2.8A)
 1.40A 4wq5B-4nzmA:
undetectable		 4wq5B-4nzmA:
24.05