SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '097'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 5 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.32A 1os2A-1r55A:
10.0		 1os2A-1r55A:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.28A 1os2D-1r55A:
10.0		 1os2D-1r55A:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5jb3 30S RIBOSOMAL
PROTEIN S9
(Pyrococcus
abyssi) 		4 / 8 ILE K  45
LEU K  49
LYS K  23
GLY K  24
 None
None
G  21097 ( 3.7A)
None
 0.84A 1os6A-5jb3K:
undetectable		 1os6A-5jb3K:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.31A 1uttA-1r55A:
10.3		 1uttA-1r55A:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.34A 1utzA-1r55A:
10.2		 1utzA-1r55A:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.34A 1utzB-1r55A:
10.3		 1utzB-1r55A:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 6 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.29A 1y93A-1r55A:
10.3		 1y93A-1r55A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.26A 2hu6A-1r55A:
10.2		 2hu6A-1r55A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1r55 ADAM 33
(Homo
sapiens) 		5 / 9 THR A 342
HIS A 345
GLU A 346
HIS A 349
HIS A 355
 097  A 518 (-3.5A)
ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.28A 2jihA-1r55A:
25.6		 2jihA-1r55A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1r55 ADAM 33
(Homo
sapiens) 		5 / 8 THR A 342
HIS A 345
GLU A 346
HIS A 349
HIS A 355
 097  A 518 (-3.5A)
ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.29A 2jihB-1r55A:
25.5		 2jihB-1r55A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 6 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.39A 2ow9A-1r55A:
9.8		 2ow9A-1r55A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.38A 2ow9B-1r55A:
9.7		 2ow9B-1r55A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.41A 2ozrC-1r55A:
8.5		 2ozrC-1r55A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.39A 2ozrD-1r55A:
9.6		 2ozrD-1r55A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.39A 2ozrE-1r55A:
9.7		 2ozrE-1r55A:
24.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1r55 ADAM 33
(Homo
sapiens) 		5 / 9 THR A 342
HIS A 345
GLU A 346
HIS A 349
HIS A 355
 097  A 518 (-3.5A)
ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.24A 3hy7A-1r55A:
26.0		 3hy7A-1r55A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1r55 ADAM 33
(Homo
sapiens) 		5 / 9 THR A 342
HIS A 345
GLU A 346
HIS A 349
HIS A 355
 097  A 518 (-3.5A)
ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.25A 3hy7B-1r55A:
25.5		 3hy7B-1r55A:
30.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 5 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.35A 3kecA-1r55A:
9.7		 3kecA-1r55A:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 5 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.30A 3likA-1r55A:
10.3		 3likA-1r55A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.31A 3lilA-1r55A:
10.3		 3lilA-1r55A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 5 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.28A 3ljgA-1r55A:
10.4		 3ljgA-1r55A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 5 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.26A 3lkaA-1r55A:
10.2		 3lkaA-1r55A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 5jb3 30S RIBOSOMAL
PROTEIN S9
(Pyrococcus
abyssi) 		4 / 8 ILE K  45
LEU K  49
LYS K  23
GLY K  24
 None
None
G  21097 ( 3.7A)
None
 0.93A 3selX-5jb3K:
undetectable		 3selX-5jb3K:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5g15 MB1 MONOBODY
(synthetic
construct) 		5 / 12 ILE B  76
VAL B  78
TYR B  38
TYR B  42
ILE B  65
 None
None
None
SO4  B1097 (-4.9A)
SO4  B1097 (-4.8A)
 1.13A 3vrjA-5g15B:
4.4
3vrjC-5g15B:
undetectable		 3vrjA-5g15B:
14.86
3vrjC-5g15B:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 6 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.47A 4a7bA-1r55A:
9.6		 4a7bA-1r55A:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5jb3 30S RIBOSOMAL
PROTEIN S9
(Pyrococcus
abyssi) 		4 / 7 ILE K  45
LEU K  49
LYS K  23
GLY K  24
 None
None
G  21097 ( 3.7A)
None
 0.74A 4hbfA-5jb3K:
undetectable		 4hbfA-5jb3K:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5jb3 30S RIBOSOMAL
PROTEIN S9
(Pyrococcus
abyssi) 		4 / 7 ILE K  45
LEU K  49
LYS K  23
GLY K  24
 None
None
G  21097 ( 3.7A)
None
 0.79A 4hc3A-5jb3K:
undetectable		 4hc3A-5jb3K:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 8 LEU A 149
THR A 226
TYR A 299
GLN A 194
 None
GLC  A3097 ( 3.0A)
GLC  A3097 ( 4.1A)
None
 1.19A 5hbsA-1fbwA:
0.0		 5hbsA-1fbwA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 4 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.28A 5n5jA-1r55A:
10.3		 5n5jA-1r55A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1r55 ADAM 33
(Homo
sapiens) 		4 / 5 HIS A 345
GLU A 346
HIS A 349
HIS A 355
 ZN  A 201 ( 3.3A)
097  A 518 (-2.9A)
ZN  A 201 ( 3.2A)
ZN  A 201 ( 3.3A)
 0.30A 5n5kA-1r55A:
10.3		 5n5kA-1r55A:
25.33