SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '04M'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 11 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.77A 1rqjA-5hn7A:
28.1
1rqjA-5hn7A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 11 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.78A 1rqjB-5hn7A:
28.1
1rqjB-5hn7A:
25.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 11 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.73A 1yhlA-5hn7A:
43.4
1yhlA-5hn7A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 11 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.57A 1yhlA-5hn7A:
43.4
1yhlA-5hn7A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
10 / 11 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.71A 1yq7A-5hn7A:
43.5
1yq7A-5hn7A:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.70A 1yv5A-5hn7A:
43.8
1yv5A-5hn7A:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.71A 1zw5A-5hn7A:
43.9
1zw5A-5hn7A:
34.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
0.72A 2e91A-5hn7A:
25.0
2e91A-5hn7A:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
0.62A 2e91B-5hn7A:
24.2
2e91B-5hn7A:
27.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.50A 2f89F-5hn7A:
44.2
2f89F-5hn7A:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
10 / 11 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.71A 2f8cF-5hn7A:
44.1
2f8cF-5hn7A:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.72A 2f8zF-5hn7A:
43.9
2f8zF-5hn7A:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
11 / 12 ASP A 126
ASP A 130
ARG A 135
THR A 191
GLN A 195
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.8A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.59A 2f94F-5hn7A:
43.9
2f94F-5hn7A:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.69A 2f9kF-5hn7A:
43.8
2f9kF-5hn7A:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
7 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
0.70A 2o1oA-5hn7A:
36.8
2o1oA-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
7 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
0.84A 2o1oB-5hn7A:
36.9
2o1oB-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 310
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
None
1.33A 2o1oB-5hn7A:
36.9
2o1oB-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
6 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
GLN A 284
ASP A 288
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
None
None
0.88A 2q58A-5hn7A:
36.7
2q58A-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
7 / 10 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
GLN A 284
ASP A 288
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
0.77A 2q58A-5hn7A:
36.7
2q58A-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
6 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
None
0.89A 2q58B-5hn7A:
36.3
2q58B-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
LYS A 310
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
1.40A 2q58B-5hn7A:
36.3
2q58B-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
6 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
0.70A 2q58B-5hn7A:
36.3
2q58B-5hn7A:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.70A 2qisA-5hn7A:
43.5
2qisA-5hn7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.80A 3ez3A-5hn7A:
53.2
3ez3A-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.67A 3ez3A-5hn7A:
53.2
3ez3A-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.74A 3ez3B-5hn7A:
52.9
3ez3B-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.81A 3ez3C-5hn7A:
53.2
3ez3C-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.69A 3ez3D-5hn7A:
52.7
3ez3D-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 10 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.57A 3ez3D-5hn7A:
52.7
3ez3D-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
10 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.72A 3ibaA-5hn7A:
43.3
3ibaA-5hn7A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.82A 3ldwA-5hn7A:
53.4
3ldwA-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.76A 3ldwB-5hn7A:
53.0
3ldwB-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.80A 3ldwC-5hn7A:
53.3
3ldwC-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.76A 3ldwD-5hn7A:
53.0
3ldwD-5hn7A:
94.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
10 / 11 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.71A 3n45F-5hn7A:
43.8
3n45F-5hn7A:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.69A 3n46F-5hn7A:
43.5
3n46F-5hn7A:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.71A 4kfaA-5hn7A:
43.3
4kfaA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.71A 4kpdA-5hn7A:
43.5
4kpdA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.56A 4kpjA-5hn7A:
43.4
4kpjA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.74A 4kq5A-5hn7A:
43.7
4kq5A-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.70A 4kqsA-5hn7A:
43.3
4kqsA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
THR A 191
GLN A 195
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.8A)
04M  A 401 (-3.3A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.71A 4n9uA-5hn7A:
43.2
4n9uA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
10 / 12 ASP A 126
ASP A 130
ARG A 135
THR A 191
GLN A 195
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.8A)
04M  A 401 (-3.3A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.53A 4ng6A-5hn7A:
43.7
4ng6A-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.79A 4nkeA-5hn7A:
43.5
4nkeA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.58A 4nkfA-5hn7A:
43.3
4nkfA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.84A 4nuaA-5hn7A:
43.4
4nuaA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
8 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.55A 4oguA-5hn7A:
43.3
4oguA-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.73A 4p0vA-5hn7A:
44.0
4p0vA-5hn7A:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
10 / 11 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.73A 4p0wA-5hn7A:
43.9
4p0wA-5hn7A:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.71A 4q23A-5hn7A:
43.3
4q23A-5hn7A:
33.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.76A 4rxdA-5hn7A:
42.8
4rxdA-5hn7A:
31.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.75A 4rxdB-5hn7A:
42.8
4rxdB-5hn7A:
31.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
9 / 10 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.75A 4rxdC-5hn7A:
42.8
4rxdC-5hn7A:
31.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 8 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
0.72A 4umjA-5hn7A:
22.6
4umjA-5hn7A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
6 / 9 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
THR A 244
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
0.68A 4umjB-5hn7A:
22.9
4umjB-5hn7A:
22.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
11 / 12 ASP A 126
ASP A 130
ARG A 135
THR A 191
GLN A 195
LYS A 243
THR A 244
TYR A 247
GLN A 284
ASP A 287
LYS A 301
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.8A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
0.66A 5cg5A-5hn7A:
43.4
5cg5A-5hn7A:
34.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
11 / 12 PHE A 122
ASP A 126
ASP A 130
ARG A 135
THR A 191
GLN A 195
LYS A 243
THR A 244
GLN A 284
ASP A 287
LYS A 301
04M  A 401 (-4.0A)
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.8A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
04M  A 401 ( 3.8A)
None
None
04M  A 401 ( 3.9A)
0.68A 5cg6A-5hn7A:
44.0
5cg6A-5hn7A:
34.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
6 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
GLN A 284
ASP A 287
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
None
0.76A 5eroA-5hn7A:
27.3
5eroA-5hn7A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 9 ASP A 126
ARG A 135
LYS A 243
ASP A 288
LYS A 301
04M  A 401 ( 4.0A)
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
04M  A 401 ( 3.9A)
1.48A 5eroB-5hn7A:
27.4
5eroB-5hn7A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
7 / 9 ASP A 126
ASP A 130
ARG A 135
LYS A 243
GLN A 284
ASP A 287
ASP A 288
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
None
None
0.81A 5eroB-5hn7A:
27.4
5eroB-5hn7A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 10 ARG A 135
LYS A 243
GLN A 284
ASP A 288
LYS A 301
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
None
04M  A 401 ( 3.9A)
1.23A 5eroC-5hn7A:
27.4
5eroC-5hn7A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 10 ASP A 126
ARG A 135
LYS A 243
GLN A 284
LYS A 301
04M  A 401 ( 4.0A)
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
04M  A 401 ( 3.9A)
1.30A 5eroC-5hn7A:
27.4
5eroC-5hn7A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
7 / 10 ASP A 126
ASP A 127
ASP A 130
ARG A 135
LYS A 243
GLN A 284
ASP A 287
04M  A 401 ( 4.0A)
None
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
None
0.74A 5eroC-5hn7A:
27.4
5eroC-5hn7A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
7 / 10 ASP A 127
ASP A 130
ARG A 135
LYS A 243
GLN A 284
ASP A 287
ASP A 288
None
None
04M  A 401 (-3.5A)
04M  A 401 (-4.5A)
None
None
None
0.78A 5eroC-5hn7A:
27.4
5eroC-5hn7A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
6 / 7 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
None
0.76A 6g31A-5hn7A:
26.1
6g31A-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 6 ASP A 126
ASP A 130
ARG A 135
GLN A 195
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
None
0.81A 6g31B-5hn7A:
26.0
6g31B-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 5 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
0.89A 6g31C-5hn7A:
26.2
6g31C-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 7 ASP A 126
ASP A 130
ARG A 135
GLN A 195
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
None
0.69A 6g31D-5hn7A:
25.5
6g31D-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 5 ASP A 126
ASP A 130
ARG A 135
GLN A 195
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
None
0.98A 6g31F-5hn7A:
26.1
6g31F-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
6 / 7 ASP A 126
ASP A 130
ARG A 135
GLN A 195
LYS A 243
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
04M  A 401 (-4.5A)
None
0.77A 6g31G-5hn7A:
25.1
6g31G-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
4 / 5 ASP A 126
ASP A 130
GLN A 195
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.3A)
None
0.73A 6g31H-5hn7A:
25.1
6g31H-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_I_ZOLI401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
4 / 4 ASP A 126
ASP A 130
LYS A 243
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-4.5A)
None
0.73A 6g31I-5hn7A:
25.1
6g31I-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 6 ASP A 126
ASP A 130
ARG A 135
GLN A 195
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
None
0.96A 6g31J-5hn7A:
26.4
6g31J-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
4 / 4 ASP A 126
ASP A 130
ARG A 135
GLN A 195
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
0.58A 6g31K-5hn7A:
24.2
6g31K-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 6 ASP A 126
ASP A 130
ARG A 135
GLN A 195
GLN A 284
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
04M  A 401 (-3.3A)
None
1.00A 6g31L-5hn7A:
25.9
6g31L-5hn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax)
5 / 6 ASP A 126
ASP A 130
ARG A 135
GLN A 284
LYS A 310
04M  A 401 ( 4.0A)
None
04M  A 401 (-3.5A)
None
None
1.29A 6g31L-5hn7A:
25.9
6g31L-5hn7A:
13.10