SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '04C'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
ALA H  27
GLY H  47
ALA H  49
SER H 169
 04C  H 301 (-2.5A)
None
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
None
 1.21A 2f162-3unfH:
30.9		 2f162-3unfH:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.59A 2f162-3unfH:
30.9		 2f162-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  27
LYS H  33
ALA H  46
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
None
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.45A 2f16H-3unfH:
35.8
2f16I-3unfH:
28.7		 2f16H-3unfH:
45.92
2f16I-3unfH:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.60A 2f16K-3unfH:
30.6
2f16L-3unfH:
25.8		 2f16K-3unfH:
26.16
2f16L-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
ALA H  27
GLY H  47
ALA H  49
SER H 169
 04C  H 301 (-2.5A)
None
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
None
 1.22A 2f16N-3unfH:
30.9		 2f16N-3unfH:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.60A 2f16N-3unfH:
30.9		 2f16N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  27
LYS H  33
ALA H  46
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
None
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.46A 2f16V-3unfH:
35.7
2f16W-3unfH:
28.7		 2f16V-3unfH:
45.92
2f16W-3unfH:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.60A 2f16Y-3unfH:
17.5
2f16Z-3unfH:
25.5		 2f16Y-3unfH:
26.16
2f16Z-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.58A 3mg02-3unfH:
30.8
3mg0V-3unfH:
35.7		 3mg02-3unfH:
27.11
3mg0V-3unfH:
45.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
ALA H  46
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.51A 3mg0H-3unfH:
35.7
3mg0I-3unfH:
28.6		 3mg0H-3unfH:
45.92
3mg0I-3unfH:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		9 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
ALA H  46
GLY H  47
ALA H  49
SER H 129
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-2.9A)
 0.52A 3mg0K-3unfH:
30.6
3mg0L-3unfH:
25.8		 3mg0K-3unfH:
26.16
3mg0L-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.59A 3mg0N-3unfH:
30.9		 3mg0N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  27
LYS H  33
ALA H  46
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
None
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.43A 3mg0V-3unfH:
35.7
3mg0W-3unfH:
28.7		 3mg0V-3unfH:
45.92
3mg0W-3unfH:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		9 / 12 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
ALA H  46
GLY H  47
ALA H  49
SER H 129
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-2.9A)
 0.54A 3mg0Y-3unfH:
17.5
3mg0Z-3unfH:
25.4		 3mg0Y-3unfH:
26.16
3mg0Z-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		4 / 8 ALA H  46
ASP H  17
ASP H 166
SER H 169
 04C  H 301 ( 4.3A)
04C  H 301 ( 4.9A)
None
None
 1.02A 3qj7A-3unfH:
undetectable
3qj7D-3unfH:
undetectable		 3qj7A-3unfH:
21.71
3qj7D-3unfH:
21.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 4qvlV-3unfH:
35.7
4qvlb-3unfH:
31.0		 4qvlV-3unfH:
46.78
4qvlb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 9 THR H   1
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.47A 4qvlH-3unfH:
33.9
4qvlI-3unfH:
28.7		 4qvlH-3unfH:
46.78
4qvlI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.57A 4qvlK-3unfH:
30.7
4qvlL-3unfH:
25.7		 4qvlK-3unfH:
26.16
4qvlL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 4qvlH-3unfH:
33.9
4qvlN-3unfH:
30.9		 4qvlH-3unfH:
46.78
4qvlN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.48A 4qvlV-3unfH:
35.7
4qvlW-3unfH:
28.7		 4qvlV-3unfH:
46.78
4qvlW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.56A 4qvlY-3unfH:
17.6
4qvlZ-3unfH:
25.5		 4qvlY-3unfH:
26.16
4qvlZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 4qvmV-3unfH:
35.7
4qvmb-3unfH:
30.9		 4qvmV-3unfH:
46.78
4qvmb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
CYH H  31
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 4qvmH-3unfH:
33.9
4qvmI-3unfH:
28.5		 4qvmH-3unfH:
46.78
4qvmI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.57A 4qvmK-3unfH:
30.6
4qvmL-3unfH:
25.7		 4qvmK-3unfH:
26.16
4qvmL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.41A 4qvmH-3unfH:
33.9
4qvmN-3unfH:
30.9		 4qvmH-3unfH:
46.78
4qvmN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.68A 4qvmH-3unfH:
33.9
4qvmN-3unfH:
30.9		 4qvmH-3unfH:
46.78
4qvmN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
CYH H  31
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 4qvmV-3unfH:
35.7
4qvmW-3unfH:
28.6		 4qvmV-3unfH:
46.78
4qvmW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.57A 4qvmY-3unfH:
17.5
4qvmZ-3unfH:
25.4		 4qvmY-3unfH:
26.16
4qvmZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.63A 4qvnV-3unfH:
35.7
4qvnb-3unfH:
30.9		 4qvnV-3unfH:
46.78
4qvnb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.68A 4qvnH-3unfH:
33.9
4qvnI-3unfH:
28.7		 4qvnH-3unfH:
46.78
4qvnI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.57A 4qvnK-3unfH:
30.8
4qvnL-3unfH:
25.7		 4qvnK-3unfH:
26.16
4qvnL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.63A 4qvnH-3unfH:
33.9
4qvnN-3unfH:
30.9		 4qvnH-3unfH:
46.78
4qvnN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.47A 4qvnV-3unfH:
35.7
4qvnW-3unfH:
28.8		 4qvnV-3unfH:
46.78
4qvnW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.56A 4qvnY-3unfH:
17.6
4qvnZ-3unfH:
25.5		 4qvnY-3unfH:
26.16
4qvnZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 4qvpV-3unfH:
35.7
4qvpb-3unfH:
30.9		 4qvpV-3unfH:
46.78
4qvpb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.59A 4qvpH-3unfH:
33.9
4qvpI-3unfH:
28.6		 4qvpH-3unfH:
46.78
4qvpI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.55A 4qvpK-3unfH:
30.7
4qvpL-3unfH:
25.5		 4qvpK-3unfH:
26.16
4qvpL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 4qvpH-3unfH:
33.9
4qvpN-3unfH:
30.9		 4qvpH-3unfH:
46.78
4qvpN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 4qvpV-3unfH:
35.7
4qvpW-3unfH:
28.7		 4qvpV-3unfH:
46.78
4qvpW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.54A 4qvpY-3unfH:
17.5
4qvpZ-3unfH:
25.5		 4qvpY-3unfH:
26.16
4qvpZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 4qvqV-3unfH:
35.7
4qvqb-3unfH:
30.9		 4qvqV-3unfH:
46.78
4qvqb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.64A 4qvqH-3unfH:
33.9
4qvqI-3unfH:
28.6		 4qvqH-3unfH:
46.78
4qvqI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.55A 4qvqK-3unfH:
30.6
4qvqL-3unfH:
25.8		 4qvqK-3unfH:
26.16
4qvqL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 4qvqH-3unfH:
33.9
4qvqN-3unfH:
30.9		 4qvqH-3unfH:
46.78
4qvqN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.64A 4qvqV-3unfH:
35.7
4qvqW-3unfH:
28.6		 4qvqV-3unfH:
46.78
4qvqW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.54A 4qvqY-3unfH:
17.5
4qvqZ-3unfH:
25.5		 4qvqY-3unfH:
26.16
4qvqZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.74A 4qvvV-3unfH:
35.7
4qvvb-3unfH:
30.8		 4qvvV-3unfH:
46.78
4qvvb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 11 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 4qvvH-3unfH:
33.8		 4qvvH-3unfH:
46.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		4 / 8 THR H   1
THR H  21
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.49A 4qvvK-3unfH:
30.4
4qvvL-3unfH:
25.6		 4qvvK-3unfH:
25.74
4qvvL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.73A 4qvvH-3unfH:
33.8
4qvvN-3unfH:
30.8		 4qvvH-3unfH:
46.78
4qvvN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 11 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 4qvvV-3unfH:
35.7		 4qvvV-3unfH:
46.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		4 / 8 THR H   1
THR H  21
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.49A 4qvvY-3unfH:
15.2
4qvvZ-3unfH:
25.3		 4qvvY-3unfH:
25.74
4qvvZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 4qvwV-3unfH:
35.8
4qvwb-3unfH:
30.9		 4qvwV-3unfH:
46.78
4qvwb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.42A 4qvwH-3unfH:
33.9
4qvwI-3unfH:
28.7		 4qvwH-3unfH:
46.78
4qvwI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 1.11A 4qvwK-3unfH:
30.6
4qvwL-3unfH:
25.6		 4qvwK-3unfH:
25.74
4qvwL-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.44A 4qvwK-3unfH:
30.6
4qvwL-3unfH:
25.6		 4qvwK-3unfH:
25.74
4qvwL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 4qvwH-3unfH:
33.9
4qvwN-3unfH:
30.9		 4qvwH-3unfH:
46.78
4qvwN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.41A 4qvwV-3unfH:
35.8
4qvwW-3unfH:
28.7		 4qvwV-3unfH:
46.78
4qvwW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 1.11A 4qvwY-3unfH:
17.4
4qvwZ-3unfH:
25.4		 4qvwY-3unfH:
25.74
4qvwZ-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.43A 4qvwY-3unfH:
17.4
4qvwZ-3unfH:
25.4		 4qvwY-3unfH:
25.74
4qvwZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.76A 4qvyV-3unfH:
35.7
4qvyb-3unfH:
30.8		 4qvyV-3unfH:
46.78
4qvyb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 11 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 4qvyH-3unfH:
33.9		 4qvyH-3unfH:
46.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
 0.32A 4qvyK-3unfH:
30.4
4qvyL-3unfH:
25.6		 4qvyK-3unfH:
25.74
4qvyL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.76A 4qvyH-3unfH:
33.9
4qvyN-3unfH:
30.8		 4qvyH-3unfH:
46.78
4qvyN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.57A 4qvyV-3unfH:
35.7
4qvyW-3unfH:
28.7		 4qvyV-3unfH:
46.78
4qvyW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
 0.32A 4qvyY-3unfH:
22.8
4qvyZ-3unfH:
25.3		 4qvyY-3unfH:
25.74
4qvyZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.68A 4qw0V-3unfH:
35.6
4qw0b-3unfH:
30.8		 4qw0V-3unfH:
46.78
4qw0b-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.43A 4qw0H-3unfH:
33.8
4qw0I-3unfH:
28.6		 4qw0H-3unfH:
46.78
4qw0I-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		4 / 7 THR H   1
ALA H  20
THR H  21
LYS H  33
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
 0.39A 4qw0K-3unfH:
30.2		 4qw0K-3unfH:
25.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.68A 4qw0H-3unfH:
33.8
4qw0N-3unfH:
30.8		 4qw0H-3unfH:
46.78
4qw0N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.43A 4qw0V-3unfH:
35.6
4qw0W-3unfH:
28.6		 4qw0V-3unfH:
46.78
4qw0W-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		4 / 7 THR H   1
ALA H  20
THR H  21
LYS H  33
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
 0.39A 4qw0Y-3unfH:
22.7		 4qw0Y-3unfH:
25.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 4qw1V-3unfH:
35.8
4qw1b-3unfH:
31.0		 4qw1V-3unfH:
46.78
4qw1b-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 4qw1H-3unfH:
34.1
4qw1I-3unfH:
28.7		 4qw1H-3unfH:
46.78
4qw1I-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.53A 4qw1K-3unfH:
30.8
4qw1L-3unfH:
25.8		 4qw1K-3unfH:
25.74
4qw1L-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 4qw1H-3unfH:
34.1
4qw1N-3unfH:
31.0		 4qw1H-3unfH:
46.78
4qw1N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 4qw1V-3unfH:
35.8
4qw1W-3unfH:
28.7		 4qw1V-3unfH:
46.78
4qw1W-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.53A 4qw1Y-3unfH:
17.6
4qw1Z-3unfH:
25.5		 4qw1Y-3unfH:
25.74
4qw1Z-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.40A 4qw3V-3unfH:
35.6
4qw3b-3unfH:
30.8		 4qw3V-3unfH:
46.78
4qw3b-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 4qw3V-3unfH:
35.6
4qw3b-3unfH:
30.8		 4qw3V-3unfH:
46.78
4qw3b-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 10 THR H   1
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.46A 4qw3H-3unfH:
33.8
4qw3I-3unfH:
28.5		 4qw3H-3unfH:
46.78
4qw3I-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.57A 4qw3K-3unfH:
30.4
4qw3L-3unfH:
25.6		 4qw3K-3unfH:
26.16
4qw3L-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.40A 4qw3H-3unfH:
33.8
4qw3N-3unfH:
30.8		 4qw3H-3unfH:
46.78
4qw3N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 4qw3H-3unfH:
33.8
4qw3N-3unfH:
30.8		 4qw3H-3unfH:
46.78
4qw3N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.61A 4qw3V-3unfH:
35.6
4qw3W-3unfH:
28.5		 4qw3V-3unfH:
46.78
4qw3W-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 10 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.56A 4qw3Y-3unfH:
17.3
4qw3Z-3unfH:
25.3		 4qw3Y-3unfH:
26.16
4qw3Z-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.40A 4qwuV-3unfH:
35.8
4qwub-3unfH:
31.0		 4qwuV-3unfH:
46.78
4qwub-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.62A 4qwuV-3unfH:
35.8
4qwub-3unfH:
31.0		 4qwuV-3unfH:
46.78
4qwub-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.63A 4qwuH-3unfH:
33.9
4qwuI-3unfH:
28.8		 4qwuH-3unfH:
46.78
4qwuI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.34A 4qwuK-3unfH:
29.4
4qwuL-3unfH:
25.5		 4qwuK-3unfH:
26.16
4qwuL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.40A 4qwuH-3unfH:
33.9
4qwuN-3unfH:
31.0		 4qwuH-3unfH:
46.78
4qwuN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.62A 4qwuH-3unfH:
33.9
4qwuN-3unfH:
31.0		 4qwuH-3unfH:
46.78
4qwuN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.62A 4qwuV-3unfH:
35.8
4qwuW-3unfH:
28.8		 4qwuV-3unfH:
46.78
4qwuW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.34A 4qwuY-3unfH:
17.3
4qwuZ-3unfH:
25.5		 4qwuY-3unfH:
26.16
4qwuZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.37A 5bxnV-3unfH:
35.4
5bxnb-3unfH:
31.0		 5bxnV-3unfH:
46.35
5bxnb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 5bxnV-3unfH:
35.4
5bxnb-3unfH:
31.0		 5bxnV-3unfH:
46.35
5bxnb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.44A 5bxnH-3unfH:
35.3
5bxnI-3unfH:
28.7		 5bxnH-3unfH:
46.35
5bxnI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.56A 5bxnK-3unfH:
30.7
5bxnL-3unfH:
25.4		 5bxnK-3unfH:
26.16
5bxnL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.37A 5bxnH-3unfH:
35.3
5bxnN-3unfH:
30.9		 5bxnH-3unfH:
46.35
5bxnN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 5bxnH-3unfH:
35.3
5bxnN-3unfH:
30.9		 5bxnH-3unfH:
46.35
5bxnN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
ALA H  46
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.54A 5bxnV-3unfH:
35.4
5bxnW-3unfH:
28.7		 5bxnV-3unfH:
46.35
5bxnW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.56A 5bxnY-3unfH:
17.5
5bxnZ-3unfH:
25.4		 5bxnY-3unfH:
26.16
5bxnZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 9 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.71A 5cz7V-3unfH:
35.7
5cz7b-3unfH:
30.9		 5cz7V-3unfH:
46.78
5cz7b-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.63A 5cz7H-3unfH:
33.9
5cz7I-3unfH:
28.7		 5cz7H-3unfH:
46.78
5cz7I-3unfH:
23.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 5cz7H-3unfH:
33.9
5cz7N-3unfH:
30.9		 5cz7H-3unfH:
46.78
5cz7N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 5cz7V-3unfH:
35.7
5cz7W-3unfH:
28.7		 5cz7V-3unfH:
46.78
5cz7W-3unfH:
23.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 5d0xV-3unfH:
35.7
5d0xb-3unfH:
30.9		 5d0xV-3unfH:
46.78
5d0xb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.71A 5d0xH-3unfH:
33.9
5d0xI-3unfH:
28.6		 5d0xH-3unfH:
46.78
5d0xI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.55A 5d0xK-3unfH:
30.6
5d0xL-3unfH:
25.7		 5d0xK-3unfH:
25.74
5d0xL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.68A 5d0xH-3unfH:
33.9
5d0xN-3unfH:
30.8		 5d0xH-3unfH:
46.78
5d0xN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 11 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 5d0xV-3unfH:
35.7		 5d0xV-3unfH:
46.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.55A 5d0xY-3unfH:
17.4
5d0xZ-3unfH:
25.4		 5d0xY-3unfH:
25.74
5d0xZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.72A 5l5fV-3unfH:
35.7
5l5fb-3unfH:
30.9		 5l5fV-3unfH:
46.78
5l5fb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.52A 5l5fH-3unfH:
33.9
5l5fI-3unfH:
28.7		 5l5fH-3unfH:
46.78
5l5fI-3unfH:
23.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.72A 5l5fH-3unfH:
33.9
5l5fN-3unfH:
30.9		 5l5fH-3unfH:
46.78
5l5fN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.51A 5l5fV-3unfH:
35.7
5l5fW-3unfH:
28.7		 5l5fV-3unfH:
46.78
5l5fW-3unfH:
23.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.65A 5l5zV-3unfH:
35.8
5l5zb-3unfH:
30.9		 5l5zV-3unfH:
46.78
5l5zb-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 12 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.71A 5l5zH-3unfH:
33.8
5l5zI-3unfH:
28.8		 5l5zH-3unfH:
46.78
5l5zI-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 THR H   1
ALA H  20
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.54A 5l5zK-3unfH:
13.8
5l5zL-3unfH:
25.4		 5l5zK-3unfH:
26.69
5l5zL-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.43A 5l5zK-3unfH:
13.8
5l5zL-3unfH:
25.4		 5l5zK-3unfH:
26.69
5l5zL-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 5l5zH-3unfH:
34.0
5l5zN-3unfH:
30.9		 5l5zH-3unfH:
46.78
5l5zN-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 12 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.70A 5l5zV-3unfH:
35.8
5l5zW-3unfH:
28.8		 5l5zV-3unfH:
46.78
5l5zW-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 THR H   1
ALA H  20
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.54A 5l5zY-3unfH:
30.9
5l5zZ-3unfH:
25.4		 5l5zY-3unfH:
26.69
5l5zZ-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
 0.43A 5l5zY-3unfH:
30.9
5l5zZ-3unfH:
25.4		 5l5zY-3unfH:
26.69
5l5zZ-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.66A 5l66V-3unfH:
35.7
5l66b-3unfH:
30.9		 5l66V-3unfH:
46.78
5l66b-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.61A 5l66H-3unfH:
33.9
5l66I-3unfH:
28.7		 5l66H-3unfH:
46.78
5l66I-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 10 THR H   1
ALA H  20
THR H  21
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.65A 5l66K-3unfH:
31.1
5l66L-3unfH:
25.7		 5l66K-3unfH:
25.85
5l66L-3unfH:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 SER H  97
THR H  56
THR H  55
ALA H  46
THR H   1
 None
None
None
04C  H 301 ( 4.3A)
04C  H 301 (-2.5A)
 1.38A 5l66H-3unfH:
33.9
5l66N-3unfH:
30.9		 5l66H-3unfH:
46.78
5l66N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.67A 5l66H-3unfH:
33.9
5l66N-3unfH:
30.9		 5l66H-3unfH:
46.78
5l66N-3unfH:
27.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.61A 5l66V-3unfH:
35.7
5l66W-3unfH:
28.7		 5l66V-3unfH:
46.78
5l66W-3unfH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 10 THR H   1
ALA H  20
THR H  21
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.65A 5l66Y-3unfH:
31.1
5l66Z-3unfH:
25.4		 5l66Y-3unfH:
25.85
5l66Z-3unfH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 5lf3b-3unfH:
30.6		 5lf3b-3unfH:
27.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 10 THR H   1
ALA H  20
THR H  21
CYH H  31
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.63A 5lf3H-3unfH:
37.7
5lf3I-3unfH:
29.1		 5lf3H-3unfH:
57.69
5lf3I-3unfH:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  20
THR H  21
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.51A 5lf3K-3unfH:
31.8
5lf3L-3unfH:
27.0		 5lf3K-3unfH:
26.52
5lf3L-3unfH:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.57A 5lf3N-3unfH:
30.6		 5lf3N-3unfH:
27.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 10 THR H   1
ALA H  20
THR H  21
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.43A 5lf3V-3unfH:
37.6
5lf3W-3unfH:
29.2		 5lf3V-3unfH:
57.69
5lf3W-3unfH:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  20
THR H  21
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.53A 5lf3Y-3unfH:
31.8
5lf3Z-3unfH:
27.0		 5lf3Y-3unfH:
26.52
5lf3Z-3unfH:
26.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.54A 5lf7V-3unfH:
37.4
5lf7b-3unfH:
30.8		 5lf7V-3unfH:
57.69
5lf7b-3unfH:
27.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 11 THR H   1
ALA H  20
THR H  21
CYH H  31
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 5lf7H-3unfH:
37.5
5lf7I-3unfH:
29.2		 5lf7H-3unfH:
57.69
5lf7I-3unfH:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  20
THR H  21
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.38A 5lf7K-3unfH:
32.0
5lf7L-3unfH:
27.0		 5lf7K-3unfH:
26.52
5lf7L-3unfH:
26.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.53A 5lf7H-3unfH:
37.5
5lf7N-3unfH:
30.8		 5lf7H-3unfH:
57.69
5lf7N-3unfH:
27.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 11 THR H   1
ALA H  20
THR H  21
CYH H  31
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 ( 3.7A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 5lf7V-3unfH:
37.4
5lf7W-3unfH:
29.3		 5lf7V-3unfH:
57.69
5lf7W-3unfH:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		6 / 11 THR H   1
ALA H  20
THR H  21
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.39A 5lf7Y-3unfH:
32.0
5lf7Z-3unfH:
27.1		 5lf7Y-3unfH:
26.52
5lf7Z-3unfH:
26.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 6hwdV-3unfH:
35.6
6hwdb-3unfH:
31.0		 6hwdV-3unfH:
37.01
6hwdb-3unfH:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 12 THR H   1
ALA H  27
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
None
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.53A 6hwdH-3unfH:
33.6
6hwdI-3unfH:
28.7		 6hwdH-3unfH:
37.01
6hwdI-3unfH:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.52A 6hwdK-3unfH:
30.8
6hwdL-3unfH:
25.9		 6hwdK-3unfH:
19.47
6hwdL-3unfH:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
ALA H 161
ALA H 133
GLY H  15
ALA H   4
 04C  H 301 (-2.5A)
None
None
None
None
 0.94A 6hwdK-3unfH:
30.8
6hwdL-3unfH:
25.9		 6hwdK-3unfH:
19.47
6hwdL-3unfH:
13.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.58A 6hwdH-3unfH:
33.6
6hwdN-3unfH:
31.0		 6hwdH-3unfH:
37.01
6hwdN-3unfH:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		8 / 11 THR H   1
ALA H  27
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 04C  H 301 (-2.5A)
None
04C  H 301 ( 3.7A)
04C  H 301 (-3.5A)
04C  H 301 ( 4.3A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
04C  H 301 (-3.8A)
 0.53A 6hwdV-3unfH:
35.6		 6hwdV-3unfH:
37.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		7 / 11 THR H   1
ALA H  20
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 04C  H 301 (-2.5A)
04C  H 301 (-3.9A)
04C  H 301 (-3.9A)
None
04C  H 301 (-3.5A)
04C  H 301 (-3.7A)
04C  H 301 (-3.6A)
 0.52A 6hwdY-3unfH:
17.8
6hwdZ-3unfH:
25.7		 6hwdY-3unfH:
19.47
6hwdZ-3unfH:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3unf PROTEASOME SUBUNIT
BETA TYPE-10
(Mus
musculus) 		5 / 11 THR H   1
ALA H 161
ALA H 133
GLY H  15
ALA H   4
 04C  H 301 (-2.5A)
None
None
None
None
 0.95A 6hwdY-3unfH:
17.8
6hwdZ-3unfH:
25.7		 6hwdY-3unfH:
19.47
6hwdZ-3unfH:
13.39