Ligand ID: YMZ


Drugbank ID:
DB00358
(Mefloquine)


Indication:
For the treatment of mild to moderate acute malaria caused by Mefloquineuine-susceptible strains of Plasmodium falciparum (both chloroquine-susceptible and resistant strains) or by Plasmodium vivax. Also for the prophylaxis of Plasmodium falciparum and Plasmodium vivax malaria infections, including prophylaxis of chloroquine-resistant strains of Plasmodium falciparum.

Get human targets for YMZ in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'YMZ' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.72A20.51
15.33
None
None
None
DMS  A 402 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.70A19.80

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
VAL B 524
TYR B 365
VAL B 382
ASP B 389
PRO B 384
1.71A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.70A19.40

None
None
None
DMS  A 404 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ASN D 203
ALA D 206
VAL D 202
ASP D 295
1.71A19.60

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ASN B 203
ALA B 206
VAL B 202
ASP B 295
1.71A19.60

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ASN C 203
ALA C 206
VAL C 202
ASP C 295
1.72A19.60

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.75A19.60

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.72A19.60

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ASN A 215
VAL A  96
ASP A 211
TYR A 217
1.65A8.57

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
LEU A 636
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.64A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
LEU A 470
ILE A 466
ASN A 312
GLU A 350
LEU A 663
1.70A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
LEU A 308
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.31A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
LEU A 127
ILE A 244
TYR A 787
PHE A 134
LEU A 247
1.46A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6m71 NSP12
(SARS-CoV-2)		4 / 6
PRO A 243
VAL A 128
ASP A  36
TYR A 732
1.65A8.57

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
LEU A 247
ILE A 244
GLU A 180
LEU A 261
LEU A 127
1.77A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
VAL B 524
TYR B 365
VAL B 382
ASP B 389
PRO B 384
1.73A11.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
LEU C 117
ILE C 231
LEU C 270
ILE C 119
LEU C 229
1.68A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ALA B 890
PRO A1069
ASP A1041
TYR A1047
1.47A6.91
15.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASN B  37
ALA B  38
PRO B 125
VAL B  36
1.52A23.53
19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
VAL C 524
TYR C 365
VAL C 382
ASP C 389
PRO C 384
1.79A11.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
LEU A 229
ILE A 231
GLU A 132
PHE A 133
ILE A 119
1.51A9.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
ASN C 388
ALA C 363
ASP C 364
TYR C 365
1.79A22.15
16.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.60A22.56
19.73
None
AMP  A 201 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN B  37
ALA B  38
PRO B 125
VAL B  36
1.63A22.56
19.73
None
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  72
ALA A  70
PRO A  74
ASP A  67
1.69A22.56
19.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE C6951
PHE C7003
LEU C6848
ILE C6969
LEU C6978
1.77A20.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ASN A 177
ALA A 176
PRO A 129
ASP A 179
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA B 288
PRO B  96
VAL B  98
ASP B 286
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
LEU C 152
ILE C 151
TYR C  95
GLU C 143
LEU C 117
1.45A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ASN A 156
ALA A 153
ASP A  76
TYR A 154
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA C 288
PRO C  96
VAL C  98
ASP C 286
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ASN B 177
ALA B 176
PRO B 129
ASP B 179
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ASN B 156
ALA B 153
ASP B  76
TYR B 154
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
LEU A 152
ILE A 151
TYR A  95
GLU A 143
LEU A 117
1.33A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wcf NSP3
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.60A
None
MES  A 201 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  72
ALA A  70
PRO A  74
ASP A  67
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 241
ALA A 242
PRO A 329
VAL A 240
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 276
ALA A 274
PRO A 278
ASP A 271
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
LYS C  50
TYR C 112
PHE C  53
LEU C 159
ILE C 146
1.78A20.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.61A
None
APR  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  72
ALA D  70
PRO D  74
ASP D  67
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  37
ALA D  38
PRO D 125
VAL D  36
1.60A
None
APR  D 201 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN B  37
ALA B  38
PRO B 125
VAL B  36
1.64A
None
APR  B 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN C  37
ALA C  38
PRO C 125
VAL C  36
1.61A
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wqd NSP8
(SARS-CoV-2)		4 / 6
ALA B 110
PRO B 116
VAL B 131
ASP B 112
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wqd NSP8
(SARS-CoV-2)		4 / 6
ALA D 110
PRO D 116
VAL D 131
ASP D 112
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ASN A 156
ALA A 153
ASP A  76
TYR A 154
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ASN A 177
ALA A 176
PRO A 129
ASP A 179
1.59A
None
None
PO4  A 504 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6y2f REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.69A19.60
19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.71A20.51
15.33
None
None
None
DMS  A 403 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN E 388
ALA E 363
ASP E 364
TYR E 365
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.67A
PEG  A 405 ( 4.9A)
None
PEG  A 405 (-4.1A)
CL  A 406 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN A  72
ALA A  70
PRO A  74
ASP A  67
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  72
ALA B  70
PRO B  74
ASP B  67
1.67A
None
None
None
EDO  C 203 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  37
ALA B  38
PRO B 125
VAL B  36
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  37
ALA D  38
PRO D 125
VAL D  36
1.62A
None
EDO  D 205 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  37
ALA C  38
PRO C 125
VAL C  36
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.60A
None
EDO  A 202 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN E  37
ALA E  38
PRO E 125
VAL E  36
1.58A
None
EPE  E 202 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
LEU B  12
ILE B  18
LEU B 109
ARG B 141
LEU B 164
1.45A23.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.61A
None
APR  A 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN E  37
ALA E  38
PRO E 125
VAL E  36
1.58A
None
APR  E 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  37
ALA C  38
PRO C 125
VAL C  36
1.61A
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  37
ALA B  38
PRO B 125
VAL B  36
1.60A
None
APR  B 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  37
ALA D  38
PRO D 125
VAL D  36
1.60A
None
APR  D 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
LEU B  12
ILE B  18
LEU B 109
ARG B 141
LEU B 164
1.46A23.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  37
ALA C  38
PRO C 125
VAL C  36
1.60A
None
MES  C 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN A  37
ALA A  38
PRO A 125
VAL A  36
1.60A
None
MES  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  37
ALA B  38
PRO B 125
VAL B  36
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 470
ILE A 466
ASN A 312
GLU A 350
LEU A 663
1.72A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7btf NSP12
(SARS-CoV-2)		5 / 11
TYR A 921
GLU A 919
PHE A 920
ILE A 888
LEU A 885
1.59A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7btf NSP12
(SARS-CoV-2)		4 / 6
PRO A 243
VAL A 128
ASP A  36
TYR A 732
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 127
ILE A 244
TYR A 787
PHE A 134
LEU A 247
1.49A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		7btf NSP12
(SARS-CoV-2)		5 / 9
VAL A 667
GLY A 683
VAL A 557
MET A 542
ASP A 684
1.75A14.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 636
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.68A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 308
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.32A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
ASN A 203
ALA A 206
VAL A 202
ASP A 295
1.73A
None
None
None
DMS  A 406 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
LEU A 247
ILE A 244
GLU A 180
LEU A 261
LEU A 127
1.57A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
LEU A 178
ILE A 244
TYR A 787
PHE A 134
LEU A 247
1.63A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
LEU A 636
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.67A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
VAL A 667
GLY A 683
VAL A 557
MET A 542
ASP A 684
1.63A14.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
PRO A 243
VAL A 128
ASP A  36
TYR A 732
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
LEU A 127
ILE A 244
TYR A 787
PHE A 134
LEU A 247
1.49A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7bv1 NSP8
(SARS-CoV-2)		4 / 6
ASN B 140
PRO B 133
ASP B 143
TYR B 138
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A 215
VAL A  96
ASP A 211
TYR A 217
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
LEU A 308
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.32A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ASN A 198
ALA A 199
PRO A 227
ASP A  92
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
LEU A 636
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.73A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
PRO A 243
VAL A 128
ASP A  36
TYR A 732
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
LEU A 470
ILE A 466
ASN A 312
GLU A 350
LEU A 663
1.76A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
LEU A 247
ILE A 244
GLU A 180
LEU A 261
LEU A 127
1.65A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
LEU A 127
ILE A 244
TYR A 787
PHE A 134
LEU A 247
1.47A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_K_YMZK301_1
(60S RIBOSOMAL
PROTEIN L13,
PUTATIVE)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
LEU A 308
ILE A 307
ILE A 632
ARG A 631
LEU A 351
1.33A13.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ASN A 198
ALA A 195
PRO A 232
ASP A  92
1.79A
None