Ligand ID: X6X


Drugbank ID:
DB01296
(Glucosamine)


Indication:
Glucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question.

Get human targets for X6X in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'X6X' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.54A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A  29
GLY A 146
VAL A  42
HIS A 164
1.79A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.52A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.60A17.00
None
None
ELL  D   3 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.58A17.00
None
None
ELL  D   3 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.44A16.94
N0A  D   2 ( 4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.57A16.94
None
None
ELL  D   3 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.56A16.94
None
None
ELL  D   3 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY C 146
VAL C 114
HIS C 163
HIS C 164
1.59A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.45A16.83
3WL  A 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.59A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS B  41
VAL B  42
ASP B 187
HIS B 164
1.69A16.83
3WL  B 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.59A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.43A16.83
3WL  A 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY B 146
VAL B 114
HIS B 163
HIS B 164
1.57A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY C 146
VAL C 114
HIS C 163
HIS C 164
1.59A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY B 146
VAL B 114
HIS B 163
HIS B 164
1.57A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.56A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.55A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 678
GLY A 679
VAL A 667
1.58A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
HIS A 572
HIS A 642
1.46A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
HIS A 599
GLY A 596
GLY A 597
VAL A 827
1.32A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 678
GLY A 679
VAL A 667
1.58A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 679
VAL A 667
ASP A 684
1.63A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 679
VAL A 667
ASP A 684
1.63A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
HIS A 572
GLY A 485
GLY A 486
HIS A 642
1.42A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
HIS A 572
GLY A 485
GLY A 486
HIS A 642
1.40A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLY A 596
GLY A 597
VAL A 827
HIS A 599
1.57A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
HIS A 572
HIS A 642
1.41A10.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.44A
None
NHE  B 203 (-4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.43A
None
NHE  B 203 (-4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
HIS B  59
GLY B  60
ASP C  82
HIS C 145
1.30A23.03
 ZN  C 201 ( 3.1A)
None
ZN  C 201 ( 2.1A)
ZN  C 201 ( 3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w4h NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.14A16.89
SAM  A7102 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.20A
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.58A
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.13A
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.56A
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.56A
None
None
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.56A
None
None
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.62A19.79
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6869
VAL C6916
ASP C6895
HIS C6867
1.62A19.79
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6869
VAL C6916
ASP C6895
HIS C6867
1.59A19.79
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.23A19.79
SAM  A7102 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
VAL C6876
ASP C6895
HIS C6867
1.22A19.79
SAM  C7105 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.16A19.79
SAM  A7102 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
VAL C6876
ASP C6895
HIS C6867
1.15A19.79
SAM  C7105 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.60A19.79
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
GLU C  51
HIS C  50
VAL C   7
HIS C  47
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
GLU B 263
HIS B 272
GLY B 266
GLY B 271
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
GLU B 263
HIS B 272
GLY B 266
GLY B 271
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
GLU C  51
HIS C  50
VAL C   7
HIS C  47
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wcf NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wcf NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.53A
None
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wcf NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.53A
None
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wcf NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wen NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wen NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wen NSP3
(SARS-CoV-2)		4 / 8
GLY A  47
GLY A  46
VAL A  49
HIS A  45
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wen NSP3
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wen NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wey NSP3
(SARS-CoV-2)		4 / 8
HIS A 249
GLY A 251
GLY A 250
VAL A 253
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wey NSP3
(SARS-CoV-2)		4 / 8
GLY A 289
VAL A 286
HIS A 298
HIS A 290
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wey NSP3
(SARS-CoV-2)		4 / 8
GLY A 289
VAL A 286
HIS A 298
HIS A 290
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wey NSP3
(SARS-CoV-2)		4 / 8
HIS A 249
GLY A 251
GLY A 250
VAL A 253
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY C6869
VAL C6916
ASP C6895
HIS C6867
1.64A
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.58A
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.23A
SAH  A7102 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.61A
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY C6879
VAL C6876
ASP C6895
HIS C6867
1.16A
SAH  C7102 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY C6879
VAL C6876
ASP C6895
HIS C6867
1.22A
SAH  C7102 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY C6869
VAL C6916
ASP C6895
HIS C6867
1.61A
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.17A
SAH  A7102 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
HIS B 145
GLY A  60
HIS A  59
ASP B  82
1.68A
 ZN  B 202 (-3.3A)
None
ZN  B 202 (-2.6A)
ZN  B 202 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6869
VAL C6916
ASP C6895
HIS C6867
1.62A
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.61A
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
VAL C6876
ASP C6895
HIS C6867
1.15A
SFG  C7103 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
VAL C6876
ASP C6895
HIS C6867
1.22A
SFG  C7103 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.17A
SFG  A7103 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.23A
SFG  A7103 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.58A
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6869
VAL C6916
ASP C6895
HIS C6867
1.59A
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
HIS A 250
GLY A 239
VAL A 295
HIS A 235
1.41A
U5P  A 401 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
HIS B 250
GLY B 239
VAL B 295
HIS B 235
1.38A
U5P  B 401 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
HIS A 250
GLY A 239
VAL A 295
HIS A 235
1.43A
U5P  A 401 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
HIS B 250
GLY B 239
VAL B 295
HIS B 235
1.40A
U5P  B 401 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.42A
U5G  A 401 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.65A
None
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
APR  A 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS D  45
GLY D  47
GLY D  46
VAL D  49
1.69A
None
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY D  85
VAL D  82
HIS D  94
HIS D  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.65A
None
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.63A
None
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 103
VAL A  77
ASP B 135
HIS B 138
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 103
VAL A  77
ASP B 135
HIS B 138
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.68A
None
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY D  85
VAL D  82
HIS D  94
HIS D  86
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.21A
SAH  A7101 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.61A
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
VAL A6876
ASP A6895
HIS A6867
1.15A
SAH  A7101 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6869
VAL A6916
ASP A6895
HIS A6867
1.58A
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS B  41
VAL B  42
ASP B 187
HIS B 164
1.34A16.83
O6K  B 401 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.53A18.60
None
None
DMS  A 405 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A  29
GLY A 146
VAL A  42
HIS A 164
1.79A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.53A18.60
None
None
DMS  A 405 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.53A
None
None
P6N  A 502 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.54A
None
None
P6N  A 502 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.54A
None
None
DMS  A 403 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.42A
PK8  A 401 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.53A
None
None
DMS  A 403 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY D  85
VAL D  82
HIS D  94
HIS D  86
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  45
GLY D  47
GLY D  46
VAL D  49
1.51A
None
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
EDO  D 209 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  45
GLY D  47
GLY D  46
VAL D  49
1.50A
None
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
EDO  D 209 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY E  85
VAL E  82
HIS E  94
HIS E  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  45
GLY E  47
GLY E  46
VAL E  49
1.49A
None
EPE  E 202 (-4.3A)
EPE  E 202 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY E  85
VAL E  82
HIS E  94
HIS E  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY D  85
VAL D  82
HIS D  94
HIS D  86
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  45
GLY E  47
GLY E  46
VAL E  49
1.49A
None
EPE  E 202 (-4.3A)
EPE  E 202 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  45
GLY E  47
GLY E  46
VAL E  49
1.66A
None
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
APR  E 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.56A
None
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.55A
None
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  45
GLY D  47
GLY D  46
VAL D  49
1.65A
None
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.60A
None
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY E  85
VAL E  82
HIS E  94
HIS E  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY D  85
VAL D  82
HIS D  94
HIS D  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.53A
None
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY D  85
VAL D  82
HIS D  94
HIS D  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.62A
None
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.54A
None
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY E  85
VAL E  82
HIS E  94
HIS E  86
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.49A
None
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.42A
None
EDO  B 203 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY C  85
VAL C  82
HIS C  94
HIS C  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.50A
None
MES  C 201 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
GLY C  47
GLY C  46
VAL C  49
1.50A
None
MES  C 201 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  85
VAL B  82
HIS B  94
HIS B  86
1.41A
None
EDO  B 203 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
GLY A  47
GLY A  46
VAL A  49
1.50A
None
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
GLY B  47
GLY B  46
VAL B  49
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY A  85
VAL A  82
HIS A  94
HIS A  86
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.52A
None
None
PJE  C   5 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A  41
VAL A  42
ASP A 187
HIS A 164
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.53A
None
None
PJE  C   5 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 683
VAL A 662
ASP A 623
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
HIS A 599
GLY A 596
GLY A 597
VAL A 827
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLY A 596
GLY A 597
VAL A 827
HIS A 599
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 559
GLY A 503
VAL A 667
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 683
VAL A 662
ASP A 623
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
HIS A 599
GLY A 596
GLY A 597
VAL A 827
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 559
GLY A 503
VAL A 667
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.60A
None
None
DMS  A 402 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 146
VAL A 114
HIS A 163
HIS A 164
1.58A
None
None
DMS  A 402 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLY A 596
GLY A 597
VAL A 827
HIS A 599
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
HIS A 599
GLY A 596
GLY A 597
VAL A 827
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
HIS A 599
GLY A 596
GLY A 597
VAL A 827
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 679
VAL A 667
ASP A 684
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 679
VAL A 667
ASP A 684
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 678
GLY A 679
VAL A 667
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLY A 596
GLY A 597
VAL A 827
HIS A 599
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 678
GLY A 679
VAL A 667
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
HIS A 599
GLY A 596
GLY A 597
VAL A 827
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 678
GLY A 679
VAL A 667
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
GLU A 665
GLY A 679
VAL A 667
ASP A 684
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
HIS A 599
GLY A 596
GLY A 597
VAL A 827
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 8
GLU A 665
GLY A 678
GLY A 679
VAL A 667
ASP A 684
1.65A
None